PDB: 5425 件ウェブページステータス検索Chemie searchBIRD

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3BJF	Pyruvate kinase M2 is a phosphotyrosine binding protein 分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, MAGNESIUM ION, OXALATE ION, ... 著者 Wu, N. 登録日 2007-12-03 公開日 2008-03-04 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Pyruvate kinase M2 is a phosphotyrosine-binding protein. Nature, 452, 2008
3AZM	Crystal Structure of Human Nucleosome Core Particle Containing H4K79Q mutation 分子名称: 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ... 著者 Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H. 登録日 2011-05-25 公開日 2011-09-21 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains Biochemistry, 50, 2011
3AZN	Crystal Structure of Human Nucleosome Core Particle Containing H4K91Q mutation 分子名称: 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ... 著者 Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H. 登録日 2011-05-25 公開日 2011-09-21 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains Biochemistry, 50, 2011
1SC7	Human DNA Topoisomerase I (70 Kda) In Complex With The Indenoisoquinoline MJ-II-38 and Covalent Complex With A 22 Base Pair DNA Duplex 分子名称: 4-(5,11-DIOXO-5H-INDENO[1,2-C]ISOQUINOLIN-6(11H)-YL)BUTANOATE, 5'-D(*(TGP)P*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3', 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*T)-3', ... 著者 Staker, B.L, Feese, M.D, Cushman, M, Pommier, Y, Zembower, D, Stewart, L, Burgin, A.B. 登録日 2004-02-11 公開日 2005-04-19 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structures of three classes of anticancer agents bound to the human topoisomerase I-DNA covalent complex J.Med.Chem., 48, 2005
3AZF	Crystal Structure of Human Nucleosome Core Particle Containing H3K79Q mutation 分子名称: 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ... 著者 Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H. 登録日 2011-05-25 公開日 2011-09-21 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains Biochemistry, 50, 2011
3AZH	Crystal Structure of Human Nucleosome Core Particle Containing H3K122Q mutation 分子名称: 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ... 著者 Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H. 登録日 2011-05-25 公開日 2011-09-21 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.49 Å) 主引用文献 Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains Biochemistry, 50, 2011
3ME3	Activator-Bound Structure of Human Pyruvate Kinase M2 分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, 3-{[4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-1,4-diazepan-1-yl]sulfonyl}aniline, Pyruvate kinase isozymes M1/M2, ... 著者 Hong, B, Dimov, S, Tempel, W, Auld, D, Thomas, C, Boxer, M, Jianq, J.-K, Skoumbourdis, A, Min, S, Southall, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Inglese, J, Park, H, Structural Genomics Consortium (SGC) 登録日 2010-03-31 公開日 2010-04-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis. Nat.Chem.Biol., 8, 2012
3AV1	The human nucleosome structure containing the histone variant H3.2 分子名称: 146-MER DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ... 著者 Tachiwana, H, Osakabe, A, Shiga, T, Miya, Y, Kimura, H, Kagawa, W, Kurumizaka, H. 登録日 2011-02-18 公開日 2011-06-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structures of human nucleosomes containing major histone H3 variants Acta Crystallogr.,Sect.D, 67, 2011
3AV2	The human nucleosome structure containing the histone variant H3.3 分子名称: 146-MER DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ... 著者 Tachiwana, H, Osakabe, A, Shiga, T, Miya, M, Kimura, H, Kagawa, W, Kurumizaka, H. 登録日 2011-02-18 公開日 2011-06-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structures of human nucleosomes containing major histone H3 variants Acta Crystallogr.,Sect.D, 67, 2011
3AZE	Crystal Structure of Human Nucleosome Core Particle Containing H3K64Q mutation 分子名称: 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ... 著者 Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H. 登録日 2011-05-25 公開日 2011-09-21 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains Biochemistry, 50, 2011
1D4U	INTERACTIONS OF HUMAN NUCLEOTIDE EXCISION REPAIR PROTEIN XPA WITH RPA70 AND DNA: CHEMICAL SHIFT MAPPING AND 15N NMR RELAXATION STUDIES 分子名称: NUCLEOTIDE EXCISION REPAIR PROTEIN XPA (XPA-MBD), ZINC ION 著者 Buchko, G.W, Daughdrill, G.W, de Lorimier, R, Rao, S, Isern, N.G, Lingbeck, J, Taylor, J, Wold, M.S, Gochin, M, Spicer, L.D, Lowry, D.F, Kennedy, M.A. 登録日 1999-10-06 公開日 1999-10-17 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Interactions of human nucleotide excision repair protein XPA with DNA and RPA70 Delta C327: chemical shift mapping and 15N NMR relaxation studies. Biochemistry, 38, 1999
1FJE	SOLUTION STRUCTURE OF NUCLEOLIN RBD12 IN COMPLEX WITH SNRE RNA 分子名称: NUCLEOLIN RBD12, SNRE RNA 著者 Allain, F.H.T, Bouvet, P, Dieckmann, T, Feigon, J. 登録日 2000-08-08 公開日 2001-01-03 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Molecular basis of sequence-specific recognition of pre-ribosomal RNA by nucleolin. EMBO J., 19, 2000
3AZG	Crystal Structure of Human Nucleosome Core Particle Containing H3K115Q mutation 分子名称: 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ... 著者 Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H. 登録日 2011-05-25 公開日 2011-09-21 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains Biochemistry, 50, 2011
3AYW	Crystal Structure of Human Nucleosome Core Particle Containing H3K56Q mutation 分子名称: 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ... 著者 Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H. 登録日 2011-05-19 公開日 2011-09-21 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains Biochemistry, 50, 2011
3AZI	Crystal Structure of Human Nucleosome Core Particle Containing H4K31Q mutation 分子名称: 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ... 著者 Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H. 登録日 2011-05-25 公開日 2011-09-21 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains Biochemistry, 50, 2011
1FJ7	SOLUTION STRUCTURE OF NUCLEOLIN RBD1 分子名称: NUCLEOLIN RBD1 著者 Allain, F.H.-T, Gilbert, D.E, Bouvet, P, Feigon, J. 登録日 2000-08-07 公開日 2000-10-16 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of the two N-terminal RNA-binding domains of nucleolin and NMR study of the interaction with its RNA target. J.Mol.Biol., 303, 2000
3N25	The structure of muscle pyruvate kinase in complex with proline, pyruvate, and Mn2+ 分子名称: 1,2-ETHANEDIOL, GLYCEROL, MANGANESE (II) ION, ... 著者 Fenton, A.W, Johnson, T.A, Holyoak, T. 登録日 2010-05-17 公開日 2010-07-28 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 The pyruvate kinase model system, a cautionary tale for the use of osmolyte perturbations to support conformational equilibria in allostery. Protein Sci., 19, 2010
1T8I	Human DNA Topoisomerase I (70 Kda) In Complex With The Poison Camptothecin and Covalent Complex With A 22 Base Pair DNA Duplex 分子名称: 4-ETHYL-4-HYDROXY-1,12-DIHYDRO-4H-2-OXA-6,12A-DIAZA-DIBENZO[B,H]FLUORENE-3,13-DIONE, 5'-D(*(TGP)P*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3', 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*T)-3', ... 著者 Staker, B.L, Feese, M.D, Cushman, M, Pommier, Y, Zembower, D, Stewart, L, Burgin, A.B. 登録日 2004-05-12 公開日 2005-05-31 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structures of three classes of anticancer agents bound to the human topoisomerase I-DNA covalent complex J.Med.Chem., 48, 2005
2ZU6	crystal structure of the eIF4A-PDCD4 complex 分子名称: 1,2-ETHANEDIOL, ACETIC ACID, Eukaryotic initiation factor 4A-I, ... 著者 Cho, Y, Chang, J.H, Sohn, S.Y. 登録日 2008-10-13 公開日 2009-02-24 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of the eIF4A-PDCD4 complex Proc.Natl.Acad.Sci.Usa, 106, 2009
1RRJ	Structural Mechanisms of Camptothecin Resistance by Mutations in Human Topoisomerase I 分子名称: (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE, 2-(1-DIMETHYLAMINOMETHYL-2-HYDROXY-8-HYDROXYMETHYL-9-OXO-9,11-DIHYDRO-INDOLIZINO[1,2-B]QUINOLIN-7-YL)-2-HYDROXY-BUTYRIC ACID, 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*T*GP*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3', ... 著者 Chrencik, J.E, Staker, B.L, Burgin, A.B, Stewart, L, Redinbo, M.R. 登録日 2003-12-08 公開日 2004-07-06 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Mechanisms of camptothecin resistance by human topoisomerase I mutations J.Mol.Biol., 339, 2004
1RKJ	Solution structure of the complex formed by the two N-terminal RNA-binding domains of nucleolin and a pre-rRNA target 分子名称: 5'-R(*GP*GP*AP*UP*GP*CP*CP*UP*CP*CP*CP*GP*AP*GP*UP*GP*CP*AP*UP*CP*C)-3', Nucleolin 著者 Johansson, C, Finger, L.D, Trantirek, L, Mueller, T.D, Kim, S, Laird-Offringa, I.A, Feigon, J. 登録日 2003-11-21 公開日 2004-04-27 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of the complex formed by the two N-terminal RNA-binding domains of nucleolin and a pre-rRNA target. J.Mol.Biol., 337, 2004
1RW2	Three-dimensional structure of Ku80 CTD 分子名称: ATP-dependent DNA helicase II, 80 kDa subunit 著者 Zhang, Z, Hu, W, Cano, L, Lee, T.D, Chen, D.J, Chen, Y. 登録日 2003-12-15 公開日 2003-12-30 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of the C-terminal domain of Ku80 suggests important sites for protein-protein interactions. STRUCTURE, 12, 2004
3BJT	Pyruvate kinase M2 is a phosphotyrosine binding protein 分子名称: MAGNESIUM ION, OXALATE ION, Pyruvate kinase isozymes M1/M2 著者 Wu, N. 登録日 2007-12-04 公開日 2008-03-04 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Pyruvate kinase M2 is a phosphotyrosine-binding protein. Nature, 452, 2008
3AZK	Crystal Structure of Human Nucleosome Core Particle Containing H4K59Q mutation 分子名称: 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ... 著者 Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H. 登録日 2011-05-25 公開日 2011-09-21 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains Biochemistry, 50, 2011
3AZJ	Crystal Structure of Human Nucleosome Core Particle Containing H4K44Q mutation 分子名称: 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ... 著者 Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H. 登録日 2011-05-25 公開日 2011-09-21 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains Biochemistry, 50, 2011

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