PDB: 697 件ウェブページステータス検索Chemie searchBIRD

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1MY4	crystal structure of glutamate receptor ligand-binding core in complex with iodo-willardiine in the Zn crystal form 分子名称: 2-AMINO-3-(5-IODO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, GLUTAMATE RECEPTOR 2, ZINC ION 著者 Jin, R, Gouaux, E. 登録日 2002-10-03 公開日 2003-06-10 最終更新日 2017-08-23 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal Biochemistry, 42, 2003
1MXZ	crystal titration experiments (AMPA co-crystals soaked in 1 uM BrW) 分子名称: GLUTAMATE RECEPTOR 2, ZINC ION 著者 Jin, R, Gouaux, E. 登録日 2002-10-03 公開日 2003-06-10 最終更新日 2017-08-23 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal. Biochemistry, 42, 2003
7RZ8	Structure of the complex of LBD-TMD part of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to agonist quisqualate 分子名称: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Glutamate receptor 2 著者 Klykov, O.V, Gangwar, S.P, Yelshanskaya, M.V, Sobolevsky, A.I. 登録日 2021-08-27 公開日 2021-10-27 最終更新日 2022-02-16 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L. Mol.Cell, 81, 2021
7RZA	Structure of the complex of AMPA receptor GluA2 with auxiliary subunit GSG1L bound to agonist quisqualate 分子名称: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 2 著者 Gangwar, S.P, Klykov, O.V, Yelshanskaya, M.V, Sobolevsky, A.I. 登録日 2021-08-27 公開日 2021-10-27 最終更新日 2022-02-16 実験手法 ELECTRON MICROSCOPY (4.26 Å) 主引用文献 Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L. Mol.Cell, 81, 2021
7RYZ	Structure of the complex of LBD-TMD part of AMPA receptor GluA2 with auxiliary subunit GSG1L bound to agonist quisqualate 分子名称: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 2 著者 Gangwar, S.P, Klykov, O.V, Yelshanskaya, M.V, Sobolevsky, A.I. 登録日 2021-08-26 公開日 2021-10-27 最終更新日 2022-02-16 実験手法 ELECTRON MICROSCOPY (4.15 Å) 主引用文献 Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L. Mol.Cell, 81, 2021
7RZ6	Structure of the complex of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to agonist glutamate 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, GLUTAMIC ACID, Glutamate receptor 2 著者 Klykov, O.V, Gangwar, S.P, Yelshanskaya, M.V, Sobolevsky, A.I. 登録日 2021-08-27 公開日 2021-10-27 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L. Mol.Cell, 81, 2021
7RZ5	Structure of the complex of LBD-TMD part of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK 200775 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Glutamate receptor 2, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid 著者 Gangwar, S.P, Klykov, O.V, Yelshanskaya, M.V, Sobolevsky, A.I. 登録日 2021-08-27 公開日 2021-10-27 最終更新日 2022-02-16 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L. Mol.Cell, 81, 2021
7RYY	Structure of the complex of LBD-TMD part of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to agonist glutamate 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, GLUTAMIC ACID, Glutamate receptor 2 著者 Klykov, O.V, Gangwar, S.P, Yelshanskaya, M.V, Sobolevsky, A.I. 登録日 2021-08-26 公開日 2021-10-27 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L. Mol.Cell, 81, 2021
7RZ9	Structure of the complex of AMPA receptor GluA2 with auxiliary subunit GSG1L in the apo state 分子名称: Glutamate receptor 2 著者 Gangwar, S.P, Klykov, O.V, Yelshanskaya, M.V, Sobolevsky, A.I. 登録日 2021-08-27 公開日 2021-10-27 最終更新日 2022-02-16 実験手法 ELECTRON MICROSCOPY (4.15 Å) 主引用文献 Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L. Mol.Cell, 81, 2021
7RZ4	Structure of the complex of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK 200775 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2, ... 著者 Gangwar, S.P, Klykov, O.V, Yelshanskaya, M.V, Sobolevsky, A.I. 登録日 2021-08-27 公開日 2021-10-27 最終更新日 2022-02-16 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L. Mol.Cell, 81, 2021
7RZ7	Structure of the complex of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to agonist Quisqualate 分子名称: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 2 著者 Klykov, O.V, Gangwar, S.P, Yelshanskaya, M.V, Sobolevsky, A.I. 登録日 2021-08-27 公開日 2021-10-27 最終更新日 2022-02-16 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L. Mol.Cell, 81, 2021
7SAB	Phencyclidine-bound GluN1a-GluN2B NMDA receptors 分子名称: 1-(PHENYL-1-CYCLOHEXYL)PIPERIDINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Chou, T.-H, Furukawa, H. 登録日 2021-09-22 公開日 2022-07-20 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Structural insights into binding of therapeutic channel blockers in NMDA receptors. Nat.Struct.Mol.Biol., 29, 2022
7SAD	Memantine-bound GluN1a-GluN2B NMDA receptors 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... 著者 Chou, T.-H, Furukawa, H. 登録日 2021-09-22 公開日 2022-07-20 実験手法 ELECTRON MICROSCOPY (3.96 Å) 主引用文献 Structural insights into binding of therapeutic channel blockers in NMDA receptors. Nat.Struct.Mol.Biol., 29, 2022
7SAA	Glycine and glutamate bound GluN1a-GluN2B NMDA receptors in non-active 1 conformation at 2.97 Angstrom resolution 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ... 著者 Chou, T.-H, Furukawa, H. 登録日 2021-09-22 公開日 2022-07-20 実験手法 ELECTRON MICROSCOPY (2.97 Å) 主引用文献 Structural insights into binding of therapeutic channel blockers in NMDA receptors. Nat.Struct.Mol.Biol., 29, 2022
7SAC	S-(+)-ketamine bound GluN1a-GluN2B NMDA receptors at 3.69 Angstrom resolution 分子名称: (2~{S})-2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Chou, T.-H, Furukawa, H. 登録日 2021-09-22 公開日 2022-07-20 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (3.69 Å) 主引用文献 Structural insights into binding of therapeutic channel blockers in NMDA receptors. Nat.Struct.Mol.Biol., 29, 2022
7TE9	Cryo-EM structure of GluN1b-2B NMDAR complexed to Fab2 class1 分子名称: Fab2 heavy chain, Fab2 light chain, Glutamate receptor ionotropic, ... 著者 Tajima, N, Furukawa, H. 登録日 2022-01-04 公開日 2022-03-02 実験手法 ELECTRON MICROSCOPY (3.92 Å) 主引用文献 Development and characterization of functional antibodies targeting NMDA receptors. Nat Commun, 13, 2022
7TES	Cryo-EM structure of GluN1b-2B NMDAR in complex with Fab5 in Non-active1 conformation 分子名称: Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ... 著者 Tajima, N, Furukawa, H. 登録日 2022-01-05 公開日 2022-03-02 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Development and characterization of functional antibodies targeting NMDA receptors. Nat Commun, 13, 2022
7TEB	Cryo-EM structure of GluN1b-2B NMDAR complexed to Fab2 non-active1-like 分子名称: Fab2 heavy chain, Fab2 light chain, Glutamate receptor ionotropic, ... 著者 Tajima, N, Furukawa, H. 登録日 2022-01-04 公開日 2022-03-02 実験手法 ELECTRON MICROSCOPY (4.23 Å) 主引用文献 Development and characterization of functional antibodies targeting NMDA receptors. Nat Commun, 13, 2022
7TER	Cryo-EM structure of GluN1b-2B NMDAR in complex with Fab5 non-active2 conformation 分子名称: Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ... 著者 Tajima, N, Furukawa, H. 登録日 2022-01-05 公開日 2022-03-02 実験手法 ELECTRON MICROSCOPY (5.23 Å) 主引用文献 Development and characterization of functional antibodies targeting NMDA receptors. Nat Commun, 13, 2022
7TEE	Cryo-EM structure of GluN1b-2B NMDAR complexed to Fab2 Non-active2-like 分子名称: Fab2 heavy chain, Fab2 light chain, Glutamate receptor ionotropic, ... 著者 Tajima, N, Furukawa, H. 登録日 2022-01-04 公開日 2022-03-02 実験手法 ELECTRON MICROSCOPY (6.59 Å) 主引用文献 Development and characterization of functional antibodies targeting NMDA receptors. Nat Commun, 13, 2022
7TET	Cryo-EM structure of GluN1b-2B NMDAR in complex with Fab5 in non-active2-like conformation 分子名称: Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ... 著者 Tajima, N, Furukawa, H. 登録日 2022-01-05 公開日 2022-03-02 実験手法 ELECTRON MICROSCOPY (4.45 Å) 主引用文献 Development and characterization of functional antibodies targeting NMDA receptors. Nat Commun, 13, 2022
7TEQ	Cryo-EM structure of GluN1b-2B NMDAR in complex with Fab5 active conformation 分子名称: Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ... 著者 Tajima, N, Furukawa, H. 登録日 2022-01-05 公開日 2022-03-02 実験手法 ELECTRON MICROSCOPY (7.51 Å) 主引用文献 Development and characterization of functional antibodies targeting NMDA receptors. Nat Commun, 13, 2022
7TNK	Complex GNNN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM) 分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera 著者 Yelshanskaya, M.V, Sobolevsky, A.I. 登録日 2022-01-21 公開日 2022-04-20 最終更新日 2022-05-18 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Opening of glutamate receptor channel to subconductance levels. Nature, 605, 2022
7TNM	Complex GNGN2 of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM) 分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera 著者 Yelshanskaya, M.V, Sobolevsky, A.I. 登録日 2022-01-21 公開日 2022-04-20 最終更新日 2022-05-18 実験手法 ELECTRON MICROSCOPY (4.74 Å) 主引用文献 Opening of glutamate receptor channel to subconductance levels. Nature, 605, 2022
7TNO	Complex GGGN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM) 分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera 著者 Yelshanskaya, M.V, Sobolevsky, A.I. 登録日 2022-01-21 公開日 2022-04-20 最終更新日 2022-05-18 実験手法 ELECTRON MICROSCOPY (4.02 Å) 主引用文献 Opening of glutamate receptor channel to subconductance levels. Nature, 605, 2022

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