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5K8D
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BU of 5k8d by Molmil
Crystal structure of rFVIIIFc
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COPPER (II) ION, ...
著者Leksa, N, Quan, C.
登録日2016-05-29
公開日2017-06-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (4.19 Å)
主引用文献The structural basis for the functional comparability of factor VIII and the long-acting variant recombinant factor VIII Fc fusion protein.
J. Thromb. Haemost., 15, 2017
3L8Q
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BU of 3l8q by Molmil
Structure analysis of the type II cohesin dyad from the adaptor ScaA scaffoldin of Acetivibrio cellulolyticus
分子名称: 1,2-ETHANEDIOL, 1,3-PROPANDIOL, Cellulosomal scaffoldin adaptor protein B, ...
著者Noach, I, Frolow, F, Bayer, E.A.
登録日2010-01-03
公開日2010-05-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Modular Arrangement of a Cellulosomal Scaffoldin Subunit Revealed from the Crystal Structure of a Cohesin Dyad
J.Mol.Biol., 399, 2010
3UKD
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BU of 3ukd by Molmil
UMP/CMP KINASE FROM SLIME MOLD COMPLEXED WITH ADP, CMP, AND ALF3
分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CYTIDINE-5'-MONOPHOSPHATE, ...
著者Schlichting, I, Reinstein, J.
登録日1997-05-20
公開日1998-05-20
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of active conformations of UMP kinase from Dictyostelium discoideum suggest phosphoryl transfer is associative.
Biochemistry, 36, 1997
8XT1
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BU of 8xt1 by Molmil
Cryo-EM structure of the human 39S mitoribosome with 5uM Tigecycline
分子名称: 16s rRNA, 39S ribosomal protein L22, mitochondrial, ...
著者Li, X, Wang, M, Cheng, J.
登録日2024-01-10
公開日2024-07-10
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
8XT3
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Cryo-EM structure of the human 39S mitoribosome with 10uM Tigecycline
分子名称: 16s rRNA, 39S ribosomal protein L22, mitochondrial, ...
著者Li, X, Wang, M, Cheng, J.
登録日2024-01-10
公開日2024-07-10
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
8XT2
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BU of 8xt2 by Molmil
Cryo-EM structure of the human 55S mitoribosome with 10uM Tigecycline
分子名称: 12s rRNA, 16s rRNA, 39S ribosomal protein L22, ...
著者Li, X, Wang, M, Cheng, J.
登録日2024-01-10
公開日2024-07-10
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
8XT0
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BU of 8xt0 by Molmil
Cryo-EM structure of the human 55S mitoribosome with 5um Tigecycline
分子名称: 12s rRNA, 16s rRNA, 39S ribosomal protein L22, ...
著者Li, X, Wang, M, Cheng, J.
登録日2024-01-10
公開日2024-07-10
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
3LAD
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BU of 3lad by Molmil
REFINED CRYSTAL STRUCTURE OF LIPOAMIDE DEHYDROGENASE FROM AZOTOBACTER VINELANDII AT 2.2 ANGSTROMS RESOLUTION. A COMPARISON WITH THE STRUCTURE OF GLUTATHIONE REDUCTASE
分子名称: DIHYDROLIPOAMIDE DEHYDROGENASE, FLAVIN-ADENINE DINUCLEOTIDE
著者Mattevi, A, Schierbeek, A.J, Hol, W.G.J.
登録日1991-12-11
公開日1994-01-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Refined crystal structure of lipoamide dehydrogenase from Azotobacter vinelandii at 2.2 A resolution. A comparison with the structure of glutathione reductase.
J.Mol.Biol., 220, 1991
8VJ7
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GluA2 bound to GYKI-52466 and Glutamate, Inhibited State 2
分子名称: 4-[(5S,8R)-8-methyl-6,7,8,9-tetrahydro-2H,5H-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-5-yl]aniline, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2
著者Hale, W.D, Montano Romero, A, Huganir, R.L, Twomey, E.C.
登録日2024-01-05
公開日2024-06-05
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (4.85 Å)
主引用文献Allosteric competition and inhibition in AMPA receptors.
Nat.Struct.Mol.Biol., 2024
9BER
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BU of 9ber by Molmil
Cryo-EM structure of the HIV-1 JR-FL IDL Env trimer in complex with PGT122 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
著者Gorman, J, Kwong, P.D.
登録日2024-04-16
公開日2024-07-31
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Design of soluble HIV-1 envelope trimers free of covalent gp120-gp41 bonds with prevalent native-like conformation.
Cell Rep, 43, 2024
6VP6
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BU of 6vp6 by Molmil
Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
分子名称: GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, MAGNESIUM ION
著者Leschziner, A, Deniston, C, Lahiri, I.
登録日2020-02-01
公開日2020-08-26
最終更新日2020-12-23
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Nature, 588, 2020
6WLN
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BU of 6wln by Molmil
hc16 ligase product models, 10.0 Angstrom resolution
分子名称: RNA (349-MER)
著者Kappel, K, Zhang, K, Su, Z, Watkins, A.M, Kladwang, W, Li, S, Pintilie, G, Topkar, V.V, Rangan, R, Zheludev, I.N, Yesselman, J.D, Chiu, W, Das, R.
登録日2020-04-20
公開日2020-07-08
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (10 Å)
主引用文献Accelerated cryo-EM-guided determination of three-dimensional RNA-only structures.
Nat.Methods, 17, 2020
3PPS
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BU of 3pps by Molmil
Crystal structure of an ascomycete fungal laccase from Thielavia arenaria
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, ...
著者Kallio, J.P, Rouvinen, J, Hakulinen, N.
登録日2010-11-25
公開日2011-05-18
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of an ascomycete fungal laccase from Thielavia arenaria--common structural features of asco-laccases.
Febs J., 278, 2011
9B17
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BU of 9b17 by Molmil
Crystal Structure of human Tryptophan 2,3-dioxygenase in complex with PAN1 inhibitor
分子名称: (5P)-5-(1H-indol-3-yl)-1-[2-(piperazin-1-yl)ethyl]-1H-1,2,3-benzotriazole, PROTOPORPHYRIN IX CONTAINING FE, Tryptophan 2,3-dioxygenase, ...
著者Geeraerts, Z, Yeh, S.-R.
登録日2024-03-13
公開日2024-08-21
最終更新日2024-09-11
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural Insights into Protein-Inhibitor Interactions in Human Tryptophan Dioxygenase.
J.Med.Chem., 67, 2024
9B1Q
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Crystal Structure of human Tryptophan 2,3-dioxygenase in complex with PYN1 inhibitor
分子名称: (5P)-1-[(imidazolidin-1-yl)methyl]-5-(1H-indol-3-yl)-1H-1,2,3-benzotriazole, PROTOPORPHYRIN IX CONTAINING FE, Tryptophan 2,3-dioxygenase, ...
著者Geeraerts, Z, Yeh, S.-R.
登録日2024-03-13
公開日2024-08-21
最終更新日2024-09-11
実験手法X-RAY DIFFRACTION (2.624 Å)
主引用文献Structural Insights into Protein-Inhibitor Interactions in Human Tryptophan Dioxygenase.
J.Med.Chem., 67, 2024
4L1E
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BU of 4l1e by Molmil
Crystal structure of C-Phycocyanin from Leptolyngbya sp. N62DM
分子名称: BILIVERDINE IX ALPHA, PHYCOCYANOBILIN, Phycocyanin alpha chain, ...
著者Singh, N.K, Raj, I, Gourinath, S, Madamwar, D.
登録日2013-06-03
公開日2014-05-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Crystal Structure and Interaction of Phycocyanin with beta-Secretase: A Putative Therapy for Alzheimer's Disease.
CNS Neurol Disord Drug Targets, 13, 2014
721P
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BU of 721p by Molmil
THREE-DIMENSIONAL STRUCTURES OF H-RAS P21 MUTANTS: MOLECULAR BASIS FOR THEIR INABILITY TO FUNCTION AS SIGNAL SWITCH MOLECULES
分子名称: H-RAS P21 PROTEIN, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
著者Krengel, U, Scherer, A, Kabsch, W, Wittinghofer, A, Pai, E.F.
登録日1991-06-06
公開日1994-01-31
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Three-dimensional structures of H-ras p21 mutants: molecular basis for their inability to function as signal switch molecules.
Cell(Cambridge,Mass.), 62, 1990
8AB3
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BU of 8ab3 by Molmil
Crystal Structure of the Lactate Dehydrogenase of Cyanobacterium Aponinum in complex with oxamate, NADH and FBP.
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 1,6-di-O-phosphono-beta-D-fructofuranose, L-lactate dehydrogenase, ...
著者Robin, A.Y, Girard, E, Madern, D.
登録日2022-07-04
公開日2022-07-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.616 Å)
主引用文献Deciphering Evolutionary Trajectories of Lactate Dehydrogenases Provides New Insights into Allostery.
Mol.Biol.Evol., 40, 2023
8B3X
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BU of 8b3x by Molmil
High resolution crystal structure of dimeric SUDV VP40
分子名称: Matrix protein VP40
著者Werner, A.-D, Norris, M, Saphire, E.O, Becker, S.
登録日2022-09-17
公開日2023-06-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.531 Å)
主引用文献The C-terminus of Sudan ebolavirus VP40 contains a functionally important CX n C motif, a target for redox modifications.
Structure, 31, 2023
3PE0
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BU of 3pe0 by Molmil
Structure of the central region of the plakin domain of plectin
分子名称: CALCIUM ION, Plectin
著者Ortega, E, de Pereda, J.M.
登録日2010-10-25
公開日2011-02-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献The Structure of the Plakin Domain of Plectin Reveals a Non-canonical SH3 Domain Interacting with Its Fourth Spectrin Repeat.
J.Biol.Chem., 286, 2011
8FCS
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BU of 8fcs by Molmil
Structure of pre-miR-31 reveals an active role in Dicer processing
分子名称: microRNA 31
著者Kotar, A, Ma, S, Keane, S.
登録日2022-12-01
公開日2023-02-22
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure of pre-miR-31 reveals an active role in Dicer processing.
Biorxiv, 2023
1EJD
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BU of 1ejd by Molmil
Crystal structure of unliganded mura (type1)
分子名称: CYCLOHEXYLAMMONIUM ION, PHOSPHATE ION, UDP-N-ACETYLGLUCOSAMINE ENOLPYRUVYLTRANSFERASE
著者Eschenburg, S, Schonbrunn, E.
登録日2000-03-02
公開日2000-10-25
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Comparative X-ray analysis of the un-liganded fosfomycin-target murA.
Proteins, 40, 2000
1EXW
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BU of 1exw by Molmil
CRYSTAL STRUCTURE OF PALMITOYL PROTEIN THIOESTERASE 1 COMPLEXED WITH HEXADECYLSULFONYL FLUORIDE
分子名称: 1-HEXADECANOSULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Bellizzi III, J.J, Clardy, J.
登録日2000-05-04
公開日2000-08-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for the insensitivity of a serine enzyme (palmitoyl-protein thioesterase) to phenylmethylsulfonyl fluoride.
J.Biol.Chem., 275, 2000
1EA7
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Sphericase
分子名称: CALCIUM ION, SERINE PROTEASE
著者Almog, O, Gonzalez, A, Klein, D, Braun, S, Shoham, G.
登録日2001-07-10
公開日2002-07-04
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (0.93 Å)
主引用文献The 0.93A Crystal Structure of Sphericase: A Calcium-Loaded Serine Protease from Bacillus Sphaericus
J.Mol.Biol., 332, 2003
1E5A
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BU of 1e5a by Molmil
Structure of human transthyretin complexed with bromophenols: a new mode of binding
分子名称: 2,4,6-TRIBROMOPHENOL, TRANSTHYRETIN
著者Ghosh, M, Meerts, I.A.T.M, Cook, A, Bergman, A, Brouwer, A, Johnson, L.N.
登録日2000-07-20
公開日2000-08-29
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of Human Transthyretin Complexed with Bromophenols : A New Mode of Binding
Acta Crystallogr.,Sect.D, 56, 2000

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