9B17
Crystal Structure of human Tryptophan 2,3-dioxygenase in complex with PAN1 inhibitor
This is a non-PDB format compatible entry.
Summary for 9B17
Entry DOI | 10.2210/pdb9b17/pdb |
Related | 8VTQ 8VUG 8W1H 8W2K 9AT2 |
Descriptor | Tryptophan 2,3-dioxygenase, PROTOPORPHYRIN IX CONTAINING FE, (5P)-5-(1H-indol-3-yl)-1-[2-(piperazin-1-yl)ethyl]-1H-1,2,3-benzotriazole, ... (5 entities in total) |
Functional Keywords | inhibitor, oxidoreductase, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 185454.81 |
Authors | |
Primary citation | Geeraerts, Z.,Ishigami, I.,Lewis-Ballester, A.,Pham, K.N.,Kozlova, A.,Mathieu, C.,Frederick, R.,Yeh, S.R. Structural Insights into Protein-Inhibitor Interactions in Human Tryptophan Dioxygenase. J.Med.Chem., 2024 Cited by PubMed: 39106326DOI: 10.1021/acs.jmedchem.4c01360 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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