PDB: 217477 件ウェブページステータス検索Chemie searchBIRD

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3GFE	Crystal Structure of p38a Mitogen-Activated Protein Kinase in Complex with a Pyrazolopyridinone Inhibitor 分子名称: Mitogen-activated protein kinase 14, N-cyclopropyl-3-{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-4-yl]amino}-4-methylbenzamide 著者 Mohr, C, Jordan, S. 登録日 2009-02-26 公開日 2009-07-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Part 1: Structure-Activity Relationship (SAR) investigations of fused pyrazoles as potent, selective and orally available inhibitors of p38alpha mitogen-activated protein kinase. Bioorg.Med.Chem.Lett., 19, 2009
1BXD	NMR STRUCTURE OF THE HISTIDINE KINASE DOMAIN OF THE E. COLI OSMOSENSOR ENVZ 分子名称: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PROTEIN (OSMOLARITY SENSOR PROTEIN (ENVZ)) 著者 Tanaka, T, Saha, S.K, Tomomori, C, Ishima, R, Liu, D, Tong, K.I, Park, H, Dutta, R, Qin, L, Swindells, M.B, Yamazaki, T, Ono, A.M, Kainosho, M, Inouye, M, Ikura, M. 登録日 1998-10-02 公開日 1999-10-02 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 NMR structure of the histidine kinase domain of the E. coli osmosensor EnvZ. Nature, 396, 1998
1BTW	Episelection: novel KI ~nanomolar inhibitors of serine proteases selected by binding or chemistry on an enzyme surface 分子名称: BETA-TRYPSIN, CALCIUM ION, N-(tert-butoxycarbonyl)-L-alanyl-N-{(1S)-5-ammonio-1-[hydroxy(3-hydroxypropoxy)boranyl]pentyl}-L-valinamide 著者 Stroud, R.M, Katz, B.A, Finer-Moore, J. 登録日 1995-05-17 公開日 1995-10-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Episelection: novel Ki approximately nanomolar inhibitors of serine proteases selected by binding or chemistry on an enzyme surface. Biochemistry, 34, 1995
3DTX	Crystal structure of HLA-B*2705 complexed with the double citrullinated vasoactive intestinal peptide type 1 receptor (VIPR) peptide (residues 400-408) 分子名称: Beta-2-microglobulin, Double citrullinated vasoactive intestinal polypeptide receptor, MHC class I antigen (Fragment) 著者 Beltrami, A, Gabdulkhakov, A, Rossmann, M, Ziegler, A, Uchanska-Ziegler, B, Saenger, W. 登録日 2008-07-16 公開日 2009-05-05 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Citrullination-and mhc polymorphism-dependent conformational changes of a self peptide To be Published
4NLU	Poliovirus Polymerase - G289A Loop Mutant 分子名称: ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ... 著者 Sholders, A.J, Peersen, O.B. 登録日 2013-11-14 公開日 2014-01-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Distinct conformations of a putative translocation element in poliovirus polymerase. J.Mol.Biol., 426, 2014
2O6R	Structural diversity of the hagfish Variable Lymphocyte Receptors B61 分子名称: Variable lymphocyte receptor B 著者 Lee, J.O, Kim, H.M, Oh, S.C. 登録日 2006-12-08 公開日 2006-12-26 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural diversity of the hagfish variable lymphocyte receptors J.Biol.Chem., 282, 2007
4NLS	Poliovirus Polymerase - S288A Loop Mutant 分子名称: ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ... 著者 Sholders, A.J, Peersen, O.B. 登録日 2013-11-14 公開日 2014-01-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Distinct conformations of a putative translocation element in poliovirus polymerase. J.Mol.Biol., 426, 2014
4NLQ	Poliovirus Polymerase - C290F Loop Mutant 分子名称: ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ... 著者 Sholders, A.J, Peersen, O.B. 登録日 2013-11-14 公開日 2014-01-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Distinct conformations of a putative translocation element in poliovirus polymerase. J.Mol.Biol., 426, 2014
1IN2	Peptide Antagonist of IGFBP1, (i,i+7) Covalently Restrained Analog 分子名称: IGFBP-1 antagonist, PENTANE 著者 Skelton, N.J, Chen, Y.M, Dubree, N, Quan, C, Jackson, D.Y, Cochran, A.G, Zobel, K, Deshayes, K, Baca, M, Pisabarro, M.T, Lowman, H.B. 登録日 2001-05-11 公開日 2001-05-30 最終更新日 2011-07-13 実験手法 SOLUTION NMR 主引用文献 Structure-function analysis of a phage display-derived peptide that binds to insulin-like growth factor binding protein 1. Biochemistry, 40, 2001
3IYR	tmRNA-SmpB: a journey to the center of the bacterial ribosome 分子名称: SsrA-binding protein, tmRNA 著者 Weis, F, Bron, P, Giudice, E, Rolland, J.P, Thomas, D, Felden, B, Gillet, R. 登録日 2010-04-16 公開日 2010-10-20 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (13 Å) 主引用文献 tmRNA-SmpB: a journey to the centre of the bacterial ribosome. Embo J., 29, 2010
3GE8	Toluene 4-monooxygenase HD T201A diferric, resting state complex 分子名称: ACETATE ION, FE (III) ION, Toluene-4-monooxygenase system protein A, ... 著者 Elsen, N.L, Bailey, L.J, Hauser, A.D, Fox, B.G. 登録日 2009-02-25 公開日 2009-07-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Role for threonine 201 in the catalytic cycle of the soluble diiron hydroxylase toluene 4-monooxygenase. Biochemistry, 48, 2009
1K1C	Solution Structure of Crh, the Bacillus subtilis Catabolite Repression HPr 分子名称: catabolite repression HPr-like protein 著者 Favier, A, Brutscher, B, Blackledge, M, Galinier, A, Deutscher, J, Penin, F, Marion, D. 登録日 2001-09-25 公開日 2001-10-17 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure and dynamics of Crh, the Bacillus subtilis catabolite repression HPr. J.Mol.Biol., 317, 2002
2F1R	Crystal Structure of molybdopterin-guanine biosynthesis protein B (mobB) 分子名称: CHLORIDE ION, PRASEODYMIUM ION, molybdopterin-guanine dinucleotide biosynthesis protein B (mobB) 著者 Damodharan, L, Eswaramoorthy, S, Kumaran, D, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2005-11-15 公開日 2005-12-06 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of molybdopterin-guanine dinucleotide biosynthesis protein B (mobB) To be Published
1AGS	A SURFACE MUTANT (G82R) OF A HUMAN ALPHA-GLUTATHIONE S-TRANSFERASE SHOWS DECREASED THERMAL STABILITY AND A NEW MODE OF MOLECULAR ASSOCIATION IN THE CRYSTAL 分子名称: GLUTATHIONE S-TRANSFERASE ALPHA, S-HEXYLGLUTATHIONE 著者 Zeng, K, Rose, J.P, Wang, B.C. 登録日 1995-01-23 公開日 1995-07-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A surface mutant (G82R) of a human alpha-glutathione S-transferase shows decreased thermal stability and a new mode of molecular association in the crystal. Proteins, 20, 1994
2EWY	Crystal structure of human BACE2 in complex with a hydroxyethylenamine transition-state inhibitor 分子名称: Beta-secretase 2, N-{(1S,2R)-1-BENZYL-2-HYDROXY-3-[(3-METHYLBENZYL)AMINO]PROPYL}DIBENZO[B,F]OXEPINE-10-CARBOXAMIDE 著者 Ostermann, N. 登録日 2005-11-07 公開日 2006-11-07 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Crystal structure of human BACE2 in complex with a hydroxyethylamine transition state inhibitor J.Mol.Biol., 355, 2006
4NLV	Poliovirus Polymerase - G289A/C290F Loop Mutant 分子名称: ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ... 著者 Sholders, A.J, Peersen, O.B. 登録日 2013-11-14 公開日 2014-01-22 最終更新日 2014-03-26 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Distinct conformations of a putative translocation element in poliovirus polymerase. J.Mol.Biol., 426, 2014
4QTH	Crystal structure of anti-uPAR Fab 8B12 分子名称: anti-uPAR antibody, heavy chain, light chain 著者 Zhao, B, Yuan, C, Luo, Z, Huang, M. 登録日 2014-07-08 公開日 2015-02-25 最終更新日 2022-08-24 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Stabilizing a flexible interdomain hinge region harboring the SMB binding site drives uPAR into its closed conformation. J.Mol.Biol., 427, 2015
4NLW	Poliovirus Polymerase - G289A/C290I Loop Mutant 分子名称: ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ... 著者 Sholders, A.J, Peersen, O.B. 登録日 2013-11-14 公開日 2014-01-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Distinct conformations of a putative translocation element in poliovirus polymerase. J.Mol.Biol., 426, 2014
4NLY	Poliovirus Polymerase - C290E Loop Mutant 分子名称: ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ... 著者 Sholders, A.J, Peersen, O.B. 登録日 2013-11-14 公開日 2014-01-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Distinct conformations of a putative translocation element in poliovirus polymerase. J.Mol.Biol., 426, 2014
4NLR	Poliovirus Polymerase - C290S Loop Mutant 分子名称: ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ... 著者 Sholders, A.J, Peersen, O.B. 登録日 2013-11-14 公開日 2014-01-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Distinct conformations of a putative translocation element in poliovirus polymerase. J.Mol.Biol., 426, 2014
4NLO	Poliovirus Polymerase - C290I Loop Mutant 分子名称: ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ... 著者 Sholders, A.J, Peersen, O.B. 登録日 2013-11-14 公開日 2014-01-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Distinct conformations of a putative translocation element in poliovirus polymerase. J.Mol.Biol., 426, 2014
1JNV	The Conformation of the Epsilon and Gamma Subunits within the E. coli F1 ATPase 分子名称: ATP SYNTHASE ALPHA CHAIN, ATP SYNTHASE BETA CHAIN, ATP SYNTHASE EPSILON CHAIN, ... 著者 Hausrath, A.C, Capaldi, R.A, Matthews, B.W. 登録日 2001-07-25 公開日 2001-12-21 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (4.4 Å) 主引用文献 The conformation of the epsilon- and gamma-subunits within the Escherichia coli F(1) ATPase. J.Biol.Chem., 276, 2001
1AXR	COOPERATIVITY BETWEEN HYDROGEN-BONDING AND CHARGE-DIPOLE INTERACTIONS IN THE INHIBITION OF BETA-GLYCOSIDASES BY AZOLOPYRIDINES: EVIDENCE FROM A STUDY WITH GLYCOGEN PHOSPHORYLASE B 分子名称: 4,5,6-TRIHYDROXY-7-HYDROXYMETHYL-4,5,6,7-TETRAHYDRO-1H-[1,2,3]TRIAZOLO[1,5-A]PYRIDIN-8-YLIUM, GLYCOGEN PHOSPHORYLASE, PHOSPHATE ION, ... 著者 Oikonomakos, N.G, Heightman, T.D. 登録日 1997-10-20 公開日 1998-01-28 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Cooperative interactions of the catalytic nucleophile and the catalytic acid in the inhibition of beta-glycosidases. Calculations and their validation by comparative kinetic and structural studies of the inhibition of glycogen phosphorylase b. HELV.CHIM.ACTA, 81, 1998
5S4J	PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 Nsp3 macrodomain in complex with SF054 分子名称: 6-chlorotetrazolo[1,5-b]pyridazine, Non-structural protein 3 著者 Fearon, D, Schuller, M, Rangel, V.L, Douangamath, A, Rack, J.G.M, Zhu, K, Aimon, A, Brandao-Neto, J, Dias, A, Dunnet, L, Gorrie-Stone, T.J, Powell, A.J, Krojer, T, Skyner, R, Thompson, W, Ahel, I, von Delft, F. 登録日 2020-11-02 公開日 2021-01-13 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.124 Å) 主引用文献 Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking. Sci Adv, 7, 2021
1B9Z	BACILLUS CEREUS BETA-AMYLASE COMPLEXED WITH MALTOSE 分子名称: ACETATE ION, CALCIUM ION, PROTEIN (BETA-AMYLASE), ... 著者 Mikami, B, Adachi, M, Kage, T, Sarikaya, E, Nanmori, T, Shinke, R, Utsumi, S. 登録日 1999-03-06 公開日 1999-03-15 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of raw starch-digesting Bacillus cereus beta-amylase complexed with maltose. Biochemistry, 38, 1999

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