PDB: 36667 件ウェブページステータス検索Chemie searchBIRD

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7RLF	Cryo-EM structure of human p97-E470D mutant bound to ATPgS. 分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase 著者 Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. 登録日 2021-07-23 公開日 2021-09-22 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation. J.Biol.Chem., 297, 2021
7RLJ	Cryo-EM structure of human p97 bound to CB-5083 and ATPgS. 分子名称: 1-[4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indole-4-carboxamide, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... 著者 Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. 登録日 2021-07-23 公開日 2021-09-22 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation. J.Biol.Chem., 297, 2021
7RLD	Cryo-EM structure of human p97-E470D mutant bound to ADP. 分子名称: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase 著者 Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. 登録日 2021-07-23 公開日 2021-09-22 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation. J.Biol.Chem., 297, 2021
7RLI	Cryo-EM structure of human p97 bound to CB-5083 and ADP. 分子名称: 1-[4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indole-4-carboxamide, ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase 著者 Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. 登録日 2021-07-23 公開日 2021-09-22 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation. J.Biol.Chem., 297, 2021
7RL2	Crystal Structure of the Human Cytochrome P450 2C9*8 (CYP2C9*8) Genetic Variant in Complex with the Drug Losartan 分子名称: Cytochrome P450 2C9, PHOSPHATE ION, POTASSIUM ION, ... 著者 Shah, M.B. 登録日 2021-07-23 公開日 2021-10-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Insights into the Genetic Variations of Human Cytochrome P450 2C9: Structural Analysis, Characterization and Comparison. Int J Mol Sci, 22, 2021
7P92	TmHydABC- T. maritima bifurcating hydrogenase with bridge domain up 分子名称: FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, Fe-hydrogenase, ... 著者 Furlan, C, Chongdar, N, Gupta, P, Lubitz, W, Ogata, H, Blaza, J.N, Birrell, J.A. 登録日 2021-07-23 公開日 2022-09-14 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Structural insight on the mechanism of an electron-bifurcating [FeFe] hydrogenase. Elife, 11, 2022
7P8N	TmHydABC- T. maritima hydrogenase with bridge closed 分子名称: FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, Fe-hydrogenase, ... 著者 Furlan, C, Chongdar, N, Gupta, P, Lubitz, W, Ogata, H, Blaza, J.N, Birrell, J.A. 登録日 2021-07-23 公開日 2022-09-14 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural insight on the mechanism of an electron-bifurcating [FeFe] hydrogenase. Elife, 11, 2022
7P91	TmHydABC- T. maritima bifurcating hydrogenase with bridge domain closed 分子名称: FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, Fe-hydrogenase, ... 著者 Furlan, C, Chongdar, N, Gupta, P, Lubitz, W, Ogata, H, Blaza, J.N, Birrell, J.A. 登録日 2021-07-23 公開日 2022-09-14 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural insight on the mechanism of an electron-bifurcating [FeFe] hydrogenase. Elife, 11, 2022
7FFL	Cryo-EM structure of VEEV VLP-LDLRAD3-D1 complex at the 2-fold axes 分子名称: CALCIUM ION, Capsid protein, Low-density lipoprotein receptor class A domain-containing protein 3, ... 著者 Zhang, X, Xiang, Y, Ma, J, Ma, B, Huang, C. 登録日 2021-07-23 公開日 2021-10-20 最終更新日 2021-11-17 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structure of Venezuelan equine encephalitis virus with its receptor LDLRAD3. Nature, 598, 2021
7FFF	Structure of Venezuelan equine encephalitis virus with the receptor LDLRAD3 分子名称: CALCIUM ION, Capsid protein, Low-density lipoprotein receptor class A domain-containing protein 3, ... 著者 Zhang, X, Xiang, Y, Ma, J, Ma, B, Huang, C. 登録日 2021-07-23 公開日 2021-10-20 最終更新日 2021-11-17 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structure of Venezuelan equine encephalitis virus with its receptor LDLRAD3. Nature, 598, 2021
7FFN	Cryo-EM structure of VEEV VLP-LDLRAD3-D1 complex at the 5-fold axes 分子名称: CALCIUM ION, Capsid protein, Low-density lipoprotein receptor class A domain-containing protein 3, ... 著者 Zhang, X, Xiang, Y, Ma, J, Ma, B, Huang, C. 登録日 2021-07-23 公開日 2021-10-20 最終更新日 2021-11-17 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structure of Venezuelan equine encephalitis virus with its receptor LDLRAD3. Nature, 598, 2021
7FFK	The 0.84 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with palmitoleic acid 分子名称: Fatty acid-binding protein, heart, HEXAETHYLENE GLYCOL, ... 著者 Sugiyama, S, Kakinouchi, K, Matsuoka, S, Tsuchikawa, H, Sonoyama, M, Inoue, Y, Hayashi, F, Murata, M. 登録日 2021-07-23 公開日 2022-07-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (0.84 Å) 主引用文献 The 0.84 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with palmitoleic acid To Be Published
7FF9	Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and Cl(triethylphosphine)gold(I) 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CHLORIDE ION, GOLD ION, ... 著者 Chew, B.L.A, Luo, D. 登録日 2021-07-23 公開日 2022-07-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Inhibitory mechanism of gold analogues against Pseudomonas global virulence factor regulator Vfr To Be Published
7RKA	Crystal structure analysis of Colorado potato beetle glutathione-S transferase LdGSTu1 分子名称: GLUTATHIONE, glutathione S-transferase u1 著者 Moural, T.W, Zhu, F. 登録日 2021-07-22 公開日 2022-07-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural and Functional Characterization of One Unclassified Glutathione S-Transferase in Xenobiotic Adaptation of Leptinotarsa decemlineata. Int J Mol Sci, 22, 2021
7RKT	Naegleria fowleri CYP51 (NfCYP51) complex with (S)-1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethyl 3-(trifluoromethyl)benzoate 分子名称: (1S)-1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethyl 3-(trifluoromethyl)benzoate, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Sharma, V, Podust, L.M. 登録日 2021-07-22 公開日 2022-07-27 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Miconazole-like Scaffold is a Promising Lead for Naegleria fowleri -Specific CYP51 Inhibitors. J.Med.Chem., 2023
7RKR	Naegleria fowleri CYP51 (NfCYP51) complex with (S)-1-(4-fluorophenyl)-2-(1H-imidazol-1-yl)ethyl 3-(trifluoromethyl)benzoate 分子名称: (1S)-1-(4-fluorophenyl)-2-(1H-imidazol-1-yl)ethyl 3-(trifluoromethyl)benzoate, CALCIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Sharma, V, Podust, L.M. 登録日 2021-07-22 公開日 2022-07-27 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Miconazole-like Scaffold is a Promising Lead for Naegleria fowleri -Specific CYP51 Inhibitors. J.Med.Chem., 2023
7RKW	Naegleria fowleri CYP51(NfCYP51) complex with (S)-1-(4-fluorophenyl)-2-(1H-imidazol-1-yl)ethyl 3,5-dichlorobenzoate 分子名称: (1S)-1-(4-fluorophenyl)-2-(1H-imidazol-1-yl)ethyl 3,5-dichlorobenzoate, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Sharma, V, Podust, L.M. 登録日 2021-07-22 公開日 2022-07-27 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Miconazole-like Scaffold is a Promising Lead for Naegleria fowleri -Specific CYP51 Inhibitors. J.Med.Chem., 2023
7RKD	X-Ray structure of Insulin Analog GLULISINE 分子名称: Insulin B chain analog, Insulin chain A, ZINC ION 著者 Reyes-Grajeda, J.P. 登録日 2021-07-22 公開日 2022-07-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Insulin ANALOGS To Be Published
7RKN	Structure of CX3CL1-US28-Gi-scFv16 in OC-state 分子名称: Antibody fragment scFv16, Fractalkine, G-protein coupled receptor homolog US28, ... 著者 Tsutsumi, N, Qu, Q, Jude, K.M, Skiniotis, G, Garcia, K.C. 登録日 2021-07-22 公開日 2022-01-26 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins Sci Adv, 8, 2022
7RKY	Binding mode of US27-Gi-scFv16 in OCL-state 分子名称: Antibody fragment scFv16, G-protein coupled receptor homolog US27, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Tsutsumi, N, Jude, K.M, Garcia, K.C. 登録日 2021-07-22 公開日 2022-01-26 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins Sci Adv, 8, 2022
7RKX	Structure of US27-Gi-scFv16 in CL-state 分子名称: Antibody fragment scFv16, G-protein coupled receptor homolog US27, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Tsutsumi, N, Jude, K.M, Garcia, K.C. 登録日 2021-07-22 公開日 2022-01-26 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins Sci Adv, 8, 2022
7RKF	Structure of CX3CL1-US28-G11iN18-scFv16 in TL-state 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody fragment scFv16, Fractalkine, ... 著者 Tsutsumi, N, Maeda, S, Qu, Q, Skiniotis, G, Kobilka, B.K, Garcia, K.C. 登録日 2021-07-22 公開日 2022-01-26 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins Sci Adv, 8, 2022
7RKM	Structure of CX3CL1-US28-Gi-scFv16 in C-state 分子名称: Antibody fragment scFv16, CHOLESTEROL, Fractalkine, ... 著者 Tsutsumi, N, Qu, Q, Jude, K.M, Skiniotis, G, Garcia, K.C. 登録日 2021-07-22 公開日 2022-01-26 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins Sci Adv, 8, 2022
7FEZ	The 0.76 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with petroselinic acid 分子名称: Fatty acid-binding protein, heart, PENTAETHYLENE GLYCOL, ... 著者 Sugiyama, S, Kakinouchi, K, Nakano, R, Matsuoka, S, Tsuchikawa, H, Sonoyama, M, Inoue, Y, Hayashi, F, Murata, M. 登録日 2021-07-22 公開日 2022-07-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (0.76 Å) 主引用文献 The 0.76 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with petroselinic acid To Be Published
7FEW	Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and auranofin gold analogues 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SULFATE ION, cAMP-activated global transcriptional regulator Vfr 著者 Chew, B.L.A, Luo, D. 登録日 2021-07-22 公開日 2022-07-27 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural basis for the inhibitory mechanism of auranofin and gold(I) analogues against Pseudomonas aeruginosa global virulence factor regulator Vfr. Comput Struct Biotechnol J, 21, 2023

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