3EAX
 
 | | Crystal structure PTP1B complex with small molecule compound LZP-6 | | 分子名称: | 4,4'-piperazine-1,4-diylbis{1-[3-(benzyloxy)phenyl]-4-oxobutane-1,3-dione}, Tyrosine-protein phosphatase non-receptor type 1 | | 著者 | Zhang, Z.-Y, Liu, S, Zhang, L.-F, Yu, X, Xue, T, Gunawan, A.M, Long, Y.-Q. | | 登録日 | 2008-08-26 | | 公開日 | 2009-07-07 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Targeting inactive enzyme conformation: aryl diketoacid derivatives as a new class of PTP1B inhibitors.
J.Am.Chem.Soc., 130, 2008
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1OUW
 | | Crystal structure of Calystegia sepium agglutinin | | 分子名称: | 1,2-ETHANEDIOL, D-MALATE, IMIDAZOLE, ... | | 著者 | Bourne, Y, Roig-Zamboni, V, Barre, A, Peumans, W.J, Astoul, C.H, van Damme, E.J.M, Rouge, P. | | 登録日 | 2003-03-25 | | 公開日 | 2003-11-11 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | | 主引用文献 | The crystal structure of the Calystegia sepium agglutinin reveals a novel quaternary arrangement of lectin subunits with a beta-prism fold
J.Biol.Chem., 279, 2004
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1P7T
 | | Structure of Escherichia coli malate synthase G:pyruvate:acetyl-Coenzyme A abortive ternary complex at 1.95 angstrom resolution | | 分子名称: | ACETYL COENZYME *A, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | | 著者 | Anstrom, D.M, Kallio, K, Remington, S.J. | | 登録日 | 2003-05-05 | | 公開日 | 2003-09-09 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structure of the Escherichia Coli Malate Synthase G:pyruvate:acetyl-coenzyme A Abortive Ternary Complex at 1.95 Angstrom Resolution
Protein Sci., 12, 2003
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1POY
 | | SPERMIDINE/PUTRESCINE-BINDING PROTEIN COMPLEXED WITH SPERMIDINE (DIMER FORM) | | 分子名称: | SPERMIDINE, SPERMIDINE/PUTRESCINE-BINDING PROTEIN | | 著者 | Sugiyama, S, Vassylyev, D.G, Matsushima, M, Morikawa, K. | | 登録日 | 1996-02-02 | | 公開日 | 1996-07-11 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of PotD, the primary receptor of the polyamine transport system in Escherichia coli.
J.Biol.Chem., 271, 1996
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1GAN
 | | COMPLEX OF TOAD OVARY GALECTIN WITH N-ACETYLGALACTOSE | | 分子名称: | GALECTIN-1, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose | | 著者 | Amzel, L.M, Bianchet, M.A, Ahmed, H, Vasta, G.R. | | 登録日 | 1996-11-06 | | 公開日 | 1997-09-04 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Soluble beta-galactosyl-binding lectin (galectin) from toad ovary: crystallographic studies of two protein-sugar complexes.
Proteins, 40, 2000
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5OY3
 | | The structural basis of the histone demethylase KDM6B histone 3 lysine 27 specificity | | 分子名称: | 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, FE (III) ION, ... | | 著者 | Jones, S.E, Olsen, L, Gajhede, M. | | 登録日 | 2017-09-07 | | 公開日 | 2017-09-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.136 Å) | | 主引用文献 | Structural Basis of Histone Demethylase KDM6B Histone 3 Lysine 27 Specificity.
Biochemistry, 57, 2018
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3TNG
 | | The crystal structure of a possible phosphate acetyl/butaryl transferase from Listeria monocytogenes EGD-e. | | 分子名称: | DI(HYDROXYETHYL)ETHER, Lmo1369 protein, NICKEL (II) ION | | 著者 | Tan, K, Zhou, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2011-09-01 | | 公開日 | 2011-09-21 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | The crystal structure of a possible phosphate acetyl/butaryl transferase from Listeria monocytogenes EGD-e.
To be Published
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4M90
 | | crystal structure of oxidized hN33/Tusc3 | | 分子名称: | Tumor suppressor candidate 3 | | 著者 | Mohorko, E, Owen, R.L, Malojcic, G, Brozzo, M.S, Aebi, M, Glockshuber, R. | | 登録日 | 2013-08-14 | | 公開日 | 2014-03-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural basis of substrate specificity of human oligosaccharyl transferase subunit n33/tusc3 and its role in regulating protein N-glycosylation.
Structure, 22, 2014
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1BJT
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2OQN
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3X21
 | | Crystal structure of Escherichia coli nitroreductase NfsB mutant T41L/N71S/F124W | | 分子名称: | FLAVIN MONONUCLEOTIDE, Oxygen-insensitive NAD(P)H nitroreductase | | 著者 | Bai, J, Yang, J, Zhou, Y, Yang, Q. | | 登録日 | 2014-12-06 | | 公開日 | 2015-05-20 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.002 Å) | | 主引用文献 | Altering the regioselectivity of a nitroreductase in the synthesis of arylhydroxylamines by structure-based engineering.
Chembiochem, 16, 2015
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3S72
 | | The origin of the hydrophobic effect in the molecular recognition of arylsulfonamides by carbonic anhydrase | | 分子名称: | 1H-benzimidazole-2-sulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... | | 著者 | Snyder, P.W, Heroux, A, Whitesides, G.W. | | 登録日 | 2011-05-26 | | 公開日 | 2011-10-19 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Mechanism of the hydrophobic effect in the biomolecular recognition of arylsulfonamides by carbonic anhydrase.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3S78
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3S77
 | | The origin of the hydrophobic effect in the molecular recognition of arylsulfonamides by carbonic anhydrase | | 分子名称: | 1,3-thiazole-2-sulfonamide, Carbonic anhydrase 2, ZINC ION | | 著者 | Snyder, P.W, Heroux, A, Whitesides, G.W. | | 登録日 | 2011-05-26 | | 公開日 | 2011-10-19 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Mechanism of the hydrophobic effect in the biomolecular recognition of arylsulfonamides by carbonic anhydrase.
Proc.Natl.Acad.Sci.USA, 108, 2011
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2YIW
 | | triazolopyridine inhibitors of p38 kinase | | 分子名称: | 1-(3-tert-butyl-1-phenyl-1H-pyrazol-5-yl)-3-(2-{[3-(1-methylethyl)[1,2,4]triazolo[4,3-a]pyridin-6-yl]sulfanyl}benzyl)urea, 2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine, MITOGEN-ACTIVATED PROTEIN KINASE 14 | | 著者 | Millan, D.S, Anderson, M, Bunnage, M.E, Burrows, J.L, Butcher, K.J, Dodd, P.G, Evans, T.J, Fairman, D.A, Hughes, S.J, Irving, S.L, Kilty, I.C, Lemaitre, A, Lewthwaite, R.A, Mahnke, A, Mathais, J.P, Philip, J, Phillips, C, Smith, R.T, Stefamiak, M.H, Yeadon, M. | | 登録日 | 2011-05-17 | | 公開日 | 2011-11-30 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Design and Synthesis of Inhaled P38 Inhibitors for the Treatment of Chronic Obstructive Pulmonary Disease.
J.Med.Chem., 54, 2011
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4IJG
 | | Crystal structure of monomeric bacteriophytochrome | | 分子名称: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Bacteriophytochrome, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Auldridge, M.E. | | 登録日 | 2012-12-21 | | 公開日 | 2013-12-25 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.701 Å) | | 主引用文献 | Origins of fluorescence in evolved bacteriophytochromes.
J.Biol.Chem., 289, 2014
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256B
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3S74
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4ITZ
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3C62
 | | Tetrameric Cytochrome cb562 (H59/D62/H63/H73/A74/H77) Assembly Stabilized by Interprotein Zinc Coordination | | 分子名称: | CALCIUM ION, PROTOPORPHYRIN IX CONTAINING FE, Soluble cytochrome b562, ... | | 著者 | Tezcan, F.A, Salgado, E.N, Lewis, R.A, Faraone-Mennella, J. | | 登録日 | 2008-02-02 | | 公開日 | 2008-05-06 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Metal-mediated self-assembly of protein superstructures: influence of secondary interactions on protein oligomerization and aggregation.
J.Am.Chem.Soc., 130, 2008
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4OQ1
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1HML
 | | ALPHA_LACTALBUMIN POSSESSES A DISTINCT ZINC BINDING SITE | | 分子名称: | ALPHA-LACTALBUMIN, CALCIUM ION, SULFATE ION, ... | | 著者 | Ren, J, Stuart, D.I, Acharya, K.R. | | 登録日 | 1994-09-29 | | 公開日 | 1995-01-26 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Alpha-lactalbumin possesses a distinct zinc binding site.
J.Biol.Chem., 268, 1993
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2WYM
 | | Structure of a metallo-b-lactamase | | 分子名称: | CITRATE ANION, GLYCEROL, L-ASCORBATE-6-PHOSPHATE LACTONASE ULAG, ... | | 著者 | Garces, F, Fernandez, F.J, Penya-Soler, E, Aguilar, J, Baldoma, L, Coll, M, Badia, J, Vega, M.C. | | 登録日 | 2009-11-16 | | 公開日 | 2010-04-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Molecular Architecture of the Mn(2+)Dependent Lactonase Ulag Reveals an Rnase-Like Metallo-Beta-Lactamase Fold and a Novel Quaternary Structure.
J.Mol.Biol., 398, 2010
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1HDR
 | | THE CRYSTALLOGRAPHIC STRUCTURE OF A HUMAN DIHYDROPTERIDINE REDUCTASE NADH BINARY COMPLEX EXPRESSED IN ESCHERICHIA COLI BY A CDNA CONSTRUCTED FROM ITS RAT HOMOLOGUE | | 分子名称: | DIHYDROPTERIDINE REDUCTASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Varughese, K.I, Su, Y, Xuong, N.H, Whiteley, J.M. | | 登録日 | 1993-08-18 | | 公開日 | 1994-08-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The crystallographic structure of a human dihydropteridine reductase NADH binary complex expressed in Escherichia coli by a cDNA constructed from its rat homologue.
J.Biol.Chem., 268, 1993
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2X7T
 | | Structures of human carbonic anhydrase II inhibitor complexes reveal a second binding site for steroidal and non-steroidal inhibitors. | | 分子名称: | (9BETA,13ALPHA,14BETA,17ALPHA)-2-ETHYLESTRA-1(10),2,4-TRIENE-3,17-DIYL DISULFAMATE, CARBONIC ANHYDRASE 2, GLYCEROL, ... | | 著者 | Cozier, G.E, Leese, M.P, Lloyd, M.D, Baker, M.D, Thiyagarajan, N, Acharya, K.R, Potter, B.V.L. | | 登録日 | 2010-03-03 | | 公開日 | 2010-03-31 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Structures of Human Carbonic Anhydrase II/Inhibitor Complexes Reveal a Second Binding Site for Steroidal and Non-Steroidal Inhibitors.
Biochemistry, 49, 2010
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