5HRX
 
 | | Crystal structure of the fifth bromodomain of human PB1 in complex with 1-butylisochromeno[3,4-c]pyrazol-5(2H)-one) compound | | 分子名称: | 1,2-ETHANEDIOL, 1-butylisochromeno[3,4-c]pyrazol-5(3H)-one, Protein polybromo-1 | | 著者 | Tallant, C, Myrianthopoulos, V, Gaboriaud-Kolar, N, Newman, J.A, Picaud, S, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Mikros, E, Knapp, S. | | 登録日 | 2016-01-24 | | 公開日 | 2016-10-12 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Discovery and Optimization of a Selective Ligand for the Switch/Sucrose Nonfermenting-Related Bromodomains of Polybromo Protein-1 by the Use of Virtual Screening and Hydration Analysis.
J.Med.Chem., 59, 2016
|
|
5HRW
 | | Crystal structure of the fifth bromodomain of human PB1 in complex with 1-propylisochromeno[3,4-c]pyrazol-5(2H)-one) compound | | 分子名称: | 1,2-ETHANEDIOL, 1-propylisochromeno[3,4-c]pyrazol-5(3H)-one, Protein polybromo-1, ... | | 著者 | Tallant, C, Myrianthopoulos, V, Gaboriaud-Kolar, N, Newman, J.A, Picaud, S, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Mikros, E, Knapp, S. | | 登録日 | 2016-01-24 | | 公開日 | 2016-10-12 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Discovery and Optimization of a Selective Ligand for the Switch/Sucrose Nonfermenting-Related Bromodomains of Polybromo Protein-1 by the Use of Virtual Screening and Hydration Analysis.
J.Med.Chem., 59, 2016
|
|
5JRG
 | | Crystal structure of the nucleosome containing the DNA with tetrahydrofuran (THF) | | 分子名称: | CHLORIDE ION, DNA (145-MER), Histone H2A type 1-B/E, ... | | 著者 | Osakabe, A, Arimura, Y, Horikoshi, N, Kurumizaka, H. | | 登録日 | 2016-05-06 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Polymorphism of apyrimidinic DNA structures in the nucleosome
Sci Rep, 7, 2017
|
|
2YT4
 | |
1TGZ
 | | Structure of human Senp2 in complex with SUMO-1 | | 分子名称: | SULFATE ION, Sentrin-specific protease 2, Ubiquitin-like protein SMT3C | | 著者 | Reverter, D, Lima, C.D. | | 登録日 | 2004-05-31 | | 公開日 | 2004-09-14 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | A basis for SUMO protease specificity provided by analysis of human Senp2 and a
Senp2-SUMO complex
Structure, 12, 2004
|
|
1WXP
 | | Solution structure of the death domain of nuclear matrix protein p84 | | 分子名称: | THO complex subunit 1 | | 著者 | Niraula, T.N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-01-28 | | 公開日 | 2005-07-28 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the death domain of nuclear matrix protein p84
To be Published
|
|
1WF1
 | | Solution structure of RRM domain in RNA-binding protein NP_057951 | | 分子名称: | RNA-binding protein Raly | | 著者 | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2004-05-25 | | 公開日 | 2004-11-25 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of RRM domain in RNA-binding protein NP_057951
To be Published
|
|
3LQV
 | |
1X5P
 | | Solution structure of RRM domain in Parp14 | | 分子名称: | Negative elongation factor E | | 著者 | Dang, W, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-05-16 | | 公開日 | 2005-11-16 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of RRM domain in Parp14
To be Published
|
|
1X4F
 | | Solution structure of the second RRM domain in Matrin 3 | | 分子名称: | Matrin 3 | | 著者 | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-05-14 | | 公開日 | 2005-11-14 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the second RRM domain in Matrin 3
To be Published
|
|
1UFG
 | | Solution structure of immunoglobulin like domain of mouse nuclear lamin | | 分子名称: | Lamin A | | 著者 | Kobayashi, N, Kigawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-05-29 | | 公開日 | 2004-06-22 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of immunoglobulin like domain of mouse nuclear lamin
To be Published
|
|
3O36
 | |
1F3W
 | | RECOMBINANT RABBIT MUSCLE PYRUVATE KINASE | | 分子名称: | MANGANESE (II) ION, POTASSIUM ION, PYRUVATE KINASE, ... | | 著者 | Wooll, J.O, Friesen, R.H.E, White, M.A, Watowich, S.J, Fox, R.O, Lee, J.C, Czerwinski, E.W. | | 登録日 | 2000-06-06 | | 公開日 | 2001-10-03 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural and functional linkages between subunit interfaces in mammalian pyruvate kinase.
J.Mol.Biol., 312, 2001
|
|
3NQU
 | |
1R49
 | | Human topoisomerase I (Topo70) double mutant K532R/Y723F | | 分子名称: | 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*TP*AP*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3', 5'-D(P*AP*AP*AP*AP*AP*TP*TP*TP*TP*TP*CP*TP*AP*AP*GP*TP*CP*TP*TP*TP*TP*T)-3', DNA topoisomerase I | | 著者 | Interthal, H, Quigley, P.M, Hol, W.G, Champoux, J.J. | | 登録日 | 2003-10-03 | | 公開日 | 2003-12-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.13 Å) | | 主引用文献 | The role of lysine 532 in the catalytic mechanism of human topoisomerase I.
J.Biol.Chem., 279, 2004
|
|
1F3X
 | | S402P MUTANT OF RABBIT MUSCLE PYRUVATE KINASE | | 分子名称: | MANGANESE (II) ION, POTASSIUM ION, PYRUVATE KINASE, ... | | 著者 | Wooll, J.O, Friesen, R.H.E, White, M.A, Watowich, S.J, Fox, R.O, Lee, J.C, Czerwinski, E.W. | | 登録日 | 2000-06-06 | | 公開日 | 2001-10-03 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural and functional linkages between subunit interfaces in mammalian pyruvate kinase.
J.Mol.Biol., 312, 2001
|
|
3A6N
 | | The nucleosome containing a testis-specific histone variant, human H3T | | 分子名称: | 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ... | | 著者 | Tachiwana, H, Kagawa, W, Osakabe, A, Koichiro, K, Shiga, T, Kimura, H, Kurumizaka, H. | | 登録日 | 2009-09-04 | | 公開日 | 2010-05-26 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis of instability of the nucleosome containing a testis-specific histone variant, human H3T
Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
1SEU
 | | Human DNA Topoisomerase I (70 Kda) In Complex With The Indolocarbazole SA315F and Covalent Complex With A 22 Base Pair DNA Duplex | | 分子名称: | 2,10-DIHYDROXY-12-(BETA-D-GLUCOPYRANOSYL)-6,7,12,13-TETRAHYDROINDOLO[2,3-A]PYRROLO[3,4-C]CARBAZOLE-5,7-DIONE, 5'-D(*(TGP)P*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3', 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*T)-3', ... | | 著者 | Staker, B.L, Feese, M.D, Cushman, M, Pommier, Y, Zembower, D, Stewart, L, Burgin, A.B. | | 登録日 | 2004-02-18 | | 公開日 | 2005-04-19 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structures of three classes of anticancer agents bound to the human topoisomerase I-DNA covalent complex
J.Med.Chem., 48, 2005
|
|
1T5A
 | | Human Pyruvate Kinase M2 | | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Dombrauckas, J.D, Santarsiero, B.D, Mesecar, A.D. | | 登録日 | 2004-05-03 | | 公開日 | 2005-07-12 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis for tumor pyruvate kinase M2 allosteric regulation and catalysis.
Biochemistry, 44, 2005
|
|
1X6E
 | | Solution structures of the C2H2 type zinc finger domain of human Zinc finger protein 24 | | 分子名称: | ZINC ION, Zinc finger protein 24 | | 著者 | Sato, M, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-05-17 | | 公開日 | 2005-11-17 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the C2H2 type zinc finger domain of human Zinc finger protein 24
To be Published
|
|
3AFA
 | | The human nucleosome structure | | 分子名称: | 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ... | | 著者 | Tachiwana, H, Kagawa, W, Osakabe, A, Koichiro, K, Shiga, T, Kimura, H, Kurumizaka, H. | | 登録日 | 2010-02-24 | | 公開日 | 2010-05-26 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis of instability of the nucleosome containing a testis-specific histone variant, human H3T
Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
5T2C
 | | CryoEM structure of the human ribosome at 3.6 Angstrom resolution | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | | 著者 | Zhang, X, Lai, M, Zhou, Z.H. | | 登録日 | 2016-08-23 | | 公開日 | 2017-01-25 | | 最終更新日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes.
Nat Commun, 7, 2016
|
|
3O33
 | |
1U9B
 | | MURINE/HUMAN UBIQUITIN-CONJUGATING ENZYME UBC9 | | 分子名称: | UBIQUITIN-CONJUGATING ENZYME E9 | | 著者 | Tong, H, Hateboer, G, Perrakis, A, Bernards, R, Sixma, T.K. | | 登録日 | 1997-05-20 | | 公開日 | 1997-07-07 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of murine/human Ubc9 provides insight into the variability of the ubiquitin-conjugating system.
J.Biol.Chem., 272, 1997
|
|
3AZL
 | | Crystal Structure of Human Nucleosome Core Particle Containing H4K77Q mutation | | 分子名称: | 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ... | | 著者 | Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H. | | 登録日 | 2011-05-25 | | 公開日 | 2011-09-21 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains
Biochemistry, 50, 2011
|
|
