PDB: 6485 件ウェブページステータス検索Chemie searchBIRD

---

5SOA	PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with Z1613492358 分子名称: (2R)-4-(1H-pyrazol-1-yl)butan-2-ol, 3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, ... 著者 Brenk, R, Georgiou, C. 登録日 2022-05-30 公開日 2023-12-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 PanDDA analysis group deposition Chemrxiv, 2023
5SNU	PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with Z2856434770 分子名称: 1-(3-chlorophenyl)-N-methylmethanamine, 3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, ... 著者 Brenk, R, Georgiou, C. 登録日 2022-05-30 公開日 2023-12-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 PanDDA analysis group deposition Chemrxiv, 2023
5SO8	PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with Z85895198 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, N-(4-fluorobenzoyl)-N-methylglycine, ... 著者 Brenk, R, Georgiou, C. 登録日 2022-05-30 公開日 2023-12-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 PanDDA analysis group deposition Chemrxiv, 2023
5SN6	PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with Z2856434942 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, PHOSPHATE ION, ... 著者 Brenk, R, Georgiou, C. 登録日 2022-05-30 公開日 2023-12-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 PanDDA analysis group deposition Chemrxiv, 2023
5SNN	PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with Z1954800564 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, 5-methoxy-1,3-benzothiazol-2-amine, DIMETHYL SULFOXIDE, ... 著者 Brenk, R, Georgiou, C. 登録日 2022-05-30 公開日 2023-12-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 PanDDA analysis group deposition Chemrxiv, 2023
5SO5	PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with JKH93B 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, PHOSPHATE ION, ... 著者 Brenk, R, Georgiou, C. 登録日 2022-05-30 公開日 2023-12-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 PanDDA analysis group deposition Chemrxiv, 2023
5SO1	PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with Z30620520 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, PHOSPHATE ION, ... 著者 Brenk, R, Georgiou, C. 登録日 2022-05-30 公開日 2023-12-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 PanDDA analysis group deposition Chemrxiv, 2023
5SOH	PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with Z31432226 分子名称: (azepan-1-yl)(2H-1,3-benzodioxol-5-yl)methanone, 3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, ... 著者 Brenk, R, Georgiou, C. 登録日 2022-05-30 公開日 2023-12-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 PanDDA analysis group deposition Chemrxiv, 2023
4K8T	Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with ethyl 3,4-diaminobenzoate 分子名称: ADENOSINE, DIMETHYL SULFOXIDE, POTASSIUM ION, ... 著者 Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2013-04-18 公開日 2013-05-01 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with ethyl 3,4-diaminobenzoate To be Published
4KAM	X-ray crystal structure of O-acetylhomoserine sulfhydrylase MetC from Mycobacterium marinum ATCC BAA-535 / M 分子名称: O-acetylhomoserine sulfhydrylase MetC, SULFATE ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2013-04-22 公開日 2013-05-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
5SXO	1.35 angstrom resolution crystal structure of beta-ketoacyl-ACP synthase II (FabF) from Listeria monocytogenes 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2 著者 Soares da Costa, T.P, Nanson, J.D, Forwood, J.K. 登録日 2016-08-09 公開日 2016-11-02 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 1.35 angstrom resolution crystal structure of beta-ketoacyl-ACP synthase II (FabF) from Listeria monocytogenes To Be Published
5XCN	Crystal structure of M120A mutant of O-acetyl-L-serine sulfahydrylase from Haemophilus influenzae 分子名称: Cysteine synthase 著者 Abhishek, K, Kumaran, S. 登録日 2017-03-23 公開日 2018-05-02 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Molecular Mechanism of Selective Substrate Engagement and Inhibitor Dis-engagement of Cysteine Synthase. J.Biol.Chem., 2020
3ALE	A type III polyketide synthase that produces diarylheptanoid 分子名称: Os07g0271500 protein 著者 Morita, H, Kato, R, Sugio, S, Abe, I. 登録日 2010-08-03 公開日 2010-11-03 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for the one-pot formation of the diarylheptanoid scaffold by curcuminoid synthase from Oryza sativa Proc.Natl.Acad.Sci.USA, 107, 2010
1TQY	The Actinorhodin Ketosynthase/Chain Length Factor 分子名称: ACETYL GROUP, Actinorhodin polyketide putative beta-ketoacyl synthase 1, Actinorhodin polyketide putative beta-ketoacyl synthase 2, ... 著者 Keatinge-Clay, A.T, Maltby, D.A, Medzihradszky, K.F, Khosla, C, Stroud, R.M. 登録日 2004-06-18 公開日 2004-07-27 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 An antibiotic factory caught in action. Nat.Struct.Mol.Biol., 11, 2004
5T0L	Crystal structure of Toxoplasma gondii TS-DHFR complexed with NADPH, dUMP, PDDF and 5-(4-(3,4-dichlorophenyl)piperazin-1-yl)pyrimidine-2,4-diamine (TRC-15) 分子名称: 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5-[4-(3,4-dichlorophenyl)piperazin-1-yl]pyrimidine-2,4-diamine, ... 著者 Thomas, S.B, Chen, Z, Lu, H, Li, Y. 登録日 2016-08-16 公開日 2016-09-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.13 Å) 主引用文献 Discovery of Potent and Selective Leads against Toxoplasma gondii Dihydrofolate Reductase via Structure-Based Design. ACS Med Chem Lett, 7, 2016
1TRG	E. COLI THYMIDYLATE SYNTHASE IN SYMMETRIC COMPLEX WITH CB3717 AND 2'-DEOXYURIDINE 5'-MONOPHOSPHATE (DUMP) 分子名称: 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE 著者 Stout, T.J, Sage, C.R, Stroud, R.M. 登録日 1998-05-21 公開日 1998-08-12 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The additivity of substrate fragments in enzyme-ligand binding. Structure, 6, 1998
6A2L	Crystal structure of quadruple mutant (N51I+C59R+S108N+I164L) Plasmodium falciparum DHFR-TS complexed with BT1, NADPH, and dUMP 分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5-(3-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)-6-ethylpyrimidine-2,4-diamine, Bifunctional dihydrofolate reductase-thymidylate synthase, ... 著者 Chitnumsub, P, Jaruwat, A, Tarnchampoo, B, Yuthavong, Y. 登録日 2018-06-12 公開日 2019-04-24 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Hybrid Inhibitors of Malarial Dihydrofolate Reductase with Dual Binding Modes That Can Forestall Resistance. ACS Med Chem Lett, 9, 2018
1LCE	LACTOBACILLUS CASEI THYMIDYLATE SYNTHASE TERNARY COMPLEX WITH DUMP AND CH2THF 分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5,10-METHYLENE-6-HYDROFOLIC ACID, THYMIDYLATE SYNTHASE 著者 Birdsall, D.L, Finer-Moore, J, Stroud, R.M. 登録日 1995-06-22 公開日 1995-10-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Refined structures of substrate-bound and phosphate-bound thymidylate synthase from Lactobacillus casei. J.Mol.Biol., 232, 1993
4MY0	Crystal Structure of GCN5-related N-acetyltransferase from Kribbella flavida 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETYL COENZYME *A, GCN5-related N-acetyltransferase, ... 著者 Kim, Y, Mack, J, Endres, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2013-09-26 公開日 2013-11-06 実験手法 X-RAY DIFFRACTION (2.101 Å) 主引用文献 Crystal Structure of GCN5-related N-acetyltransferase from Kribbella flavida To be Published
4KPW	Crystal structure of His-tagged human thymidylate synthase R175A mutant 分子名称: 1,2-ETHANEDIOL, SULFATE ION, Thymidylate synthase 著者 Pozzi, C, Mangani, S. 登録日 2013-05-14 公開日 2014-05-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Hotspots in an obligate homodimeric anticancer target. Structural and functional effects of interfacial mutations in human thymidylate synthase. J.Med.Chem., 58, 2015
4KQ5	Crystal Structure of Human Farnesyl Pyrophosphate Synthase Mutant (Y204A) Complexed with Mg and Zoledronate 分子名称: 1,2-ETHANEDIOL, Farnesyl pyrophosphate synthase, MAGNESIUM ION, ... 著者 Barnett, B.L, Tsoumpra, M.K, Muniz, J.R.C. 登録日 2013-05-14 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of Human Farnesyl Pyrophosphate Synthase Mutant (Y204A) Complexed with Mg and Zoledronate To be Published
1LL0	Crystal Structure of Rabbit Muscle Glycogenin 分子名称: GLYCOGENIN-1 著者 Gibbons, B.J, Roach, P.J, Hurley, T.D. 登録日 2002-04-26 公開日 2002-05-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.43 Å) 主引用文献 Crystal structure of the autocatalytic initiator of glycogen biosynthesis, glycogenin. J.Mol.Biol., 319, 2002
1LL3	Crystal Structure of Rabbit Muscle Glycogenin 分子名称: GLYCEROL, GLYCOGENIN-1 著者 Gibbons, B.J, Roach, P.J, Hurley, T.D. 登録日 2002-04-26 公開日 2002-05-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of the autocatalytic initiator of glycogen biosynthesis, glycogenin. J.Mol.Biol., 319, 2002
1ULQ	Crystal structure of tt0182 from Thermus thermophilus HB8 分子名称: putative acetyl-CoA acetyltransferase 著者 Ago, H, Hamada, K, Ida, K, Kanda, H, Sugahara, M, Yamamoto, M, Kuroishi, C, Kuramitsu, S, Yokoyama, S, Miyano, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2003-09-16 公開日 2004-11-02 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of tt0182 from Thermus thermophilus HB8 To be Published
1UMX	PHOTOSYNTHETIC REACTION CENTER MUTANT WITH ARG M267 REPLACED WITH LEU (CHAIN M, R267L) 分子名称: BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN B, FE (III) ION, ... 著者 Fyfe, P.K, Isaacs, N.W, Cogdell, R.J, Jones, M.R. 登録日 2003-09-02 公開日 2004-06-29 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Disruption of a specific molecular interaction with a bound lipid affects the thermal stability of the purple bacterial reaction centre. Biochim.Biophys.Acta, 1608, 2004

<230231232233234235236237238239240241242243244245>