3KP6
| Staphylococcus epidermidis TcaR in complex with salicylate | 分子名称: | 2-HYDROXYBENZOIC ACID, CACODYLATE ION, Transcriptional regulator TcaR | 著者 | Chang, Y.M, Chen, C.K, Yeh, Y.J, Wang, A.H. | 登録日 | 2009-11-15 | 公開日 | 2010-09-29 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Structural study of TcaR and its complexes with multiple antibiotics from Staphylococcus epidermidis. Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
2W5U
| Flavodoxin from Helicobacter pylori in complex with the C3 inhibitor | 分子名称: | FLAVIN MONONUCLEOTIDE, Flavodoxin, [2-(5-amino-4-cyano-1H-pyrazol-1-yl)-5-(trifluoromethyl)phenyl](hydroxy)oxoammonium | 著者 | Cremades, N, Perez-Dorado, I, Hermoso, J.A, Martinez-Julvez, M, Sancho, J. | 登録日 | 2008-12-12 | 公開日 | 2009-12-22 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | Discovery of Specific Flavodoxin Inhibitors as Potential Therapeutic Agents Against Helicobacter Pylori Infection. Acs Chem.Biol., 4, 2009
|
|
3HZS
| S. aureus monofunctional glycosyltransferase (MtgA)in complex with moenomycin | 分子名称: | MOENOMYCIN, Monofunctional glycosyltransferase, PHOSPHATE ION | 著者 | Heaslet, H, Miller, A.A, Shaw, B, Mistry, A. | 登録日 | 2009-06-24 | 公開日 | 2009-07-07 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Characterization of the active site of S. aureus monofunctional glycosyltransferase (Mtg) by site-directed mutation and structural analysis of the protein complexed with moenomycin J.Struct.Biol., 167, 2009
|
|
2X0E
| Complex structure of WsaF with dTDP | 分子名称: | GLYCEROL, THYMIDINE-5'-DIPHOSPHATE, WSAF | 著者 | Steiner, K, Hagelueken, G, Naismith, J.H. | 登録日 | 2009-12-08 | 公開日 | 2010-02-02 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Structural Basis of Substrate Binding in Wsaf, a Rhamnosyltransferase from Geobacillus Stearothermophilus. J.Mol.Biol., 397, 2010
|
|
2WRZ
| Crystal structure of an arabinose binding protein with designed serotonin binding site in open, ligand-free state | 分子名称: | L-ARABINOSE-BINDING PERIPLASMIC PROTEIN | 著者 | Schreier, B, Stumpp, C, Wiesner, S, Hocker, B. | 登録日 | 2009-09-03 | 公開日 | 2009-10-13 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The Computational Design of Ligand Binding is not a Solved Problem Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
2X2L
| Crystal Structure of phosphorylated RET tyrosine kinase domain with inhibitor | 分子名称: | (3Z)-5-AMINO-3-[(4-METHOXYPHENYL)METHYLIDENE]-1,3-DIHYDRO-2H-INDOL-2-ONE, FORMIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET | 著者 | Knowles, P.P, Murray-Rust, J, Kjaer, S, McDonald, N.Q. | 登録日 | 2010-01-13 | 公開日 | 2010-02-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Synthesis, structure-activity relationship and crystallographic studies of 3-substituted indolin-2-one RET inhibitors. Bioorg. Med. Chem., 18, 2010
|
|
2XPU
| TetR(D) in complex with anhydrotetracycline. | 分子名称: | 5A,6-ANHYDROTETRACYCLINE, CHLORIDE ION, SULFATE ION, ... | 著者 | Dalm, D, Palm, G.J, Hinrichs, W. | 登録日 | 2010-08-30 | 公開日 | 2011-09-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Tetracycline Repressor Allostery Does not Depend on Divalent Metal Recognition. Biochemistry, 53, 2014
|
|
3LPC
| Crystal structure of a subtilisin-like protease | 分子名称: | ACETATE ION, AprB2, CALCIUM ION, ... | 著者 | Porter, C.J, Wong, W, Whisstock, J.C, Rood, J.I, Kennan, R.M. | 登録日 | 2010-02-05 | 公開日 | 2010-12-08 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The Subtilisin-Like Protease AprV2 Is Required for Virulence and Uses a Novel Disulphide-Tethered Exosite to Bind Substrates Plos Pathog., 6, 2010
|
|
2XSB
| OgOGA PUGNAc complex | 分子名称: | 2-(acetylamido)-2-deoxy-D-glucono-1,5-lactone, CHLORIDE ION, HYALURONOGLUCOSAMINIDASE | 著者 | Schuttelkopf, A.W, van Aalten, D.M.F. | 登録日 | 2010-09-27 | 公開日 | 2011-03-23 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Human Oga Binds Substrates in a Conserved Peptide Recognition Groove. Biochem.J., 432, 2010
|
|
2XYP
| Caspase-3:CAS26049945 | 分子名称: | CASPASE-3 SUBUNIT P12, CASPASE-3 SUBUNIT P17, PHENYLMETHYL N-[(2S)-4-CHLORO-3-OXO-1-PHENYL-BUTAN-2-YL]CARBAMATE | 著者 | Ganesan, R, Jelakovic, S, Grutter, M.G, Mittl, P.R. | 登録日 | 2010-11-18 | 公開日 | 2011-08-17 | 最終更新日 | 2017-06-28 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | In Silico Identification and Crystal Structure Validation of Caspase-3 Inhibitors without a P1 Aspartic Acid Moiety. Acta Crystallogr.,Sect.F, 67, 2011
|
|
3KOB
| |
3KP2
| |
3KP7
| Staphylococcus epidermidis TcaR (apo form) | 分子名称: | Transcriptional regulator TcaR | 著者 | Chang, Y.M, Chen, C.K, Yeh, Y.J, Ko, T.P, Wang, A.H. | 登録日 | 2009-11-15 | 公開日 | 2010-06-09 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural study of TcaR and its complexes with multiple antibiotics from Staphylococcus epidermidis. Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
3KO4
| |
3KOC
| |
3GMY
| |
2VFW
| Rv1086 native | 分子名称: | SHORT-CHAIN Z-ISOPRENYL DIPHOSPHATE SYNTHETASE, SULFATE ION | 著者 | Naismith, J.H, Wang, W, Dong, C. | 登録日 | 2007-11-05 | 公開日 | 2007-11-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The structural basis of chain length control in Rv1086. J. Mol. Biol., 381, 2008
|
|
3GTC
| AmpC beta-lactamase in complex with Fragment-based Inhibitor | 分子名称: | (1R,2S)-2-(5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)cyclohexanecarboxylic acid, Beta-lactamase, PHOSPHATE ION | 著者 | Teotico, D.T, Shoichet, B.K. | 登録日 | 2009-03-27 | 公開日 | 2009-04-14 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Docking for fragment inhibitors of AmpC beta-lactamase Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
3KNF
| |
3KRD
| |
3KXH
| Crystal structure of Z. mays CK2 kinase alpha subunit in complex with the inhibitor (2-dymethylammino-4,5,6,7-tetrabromobenzoimidazol-1yl-acetic acid (K66) | 分子名称: | Casein kinase II subunit alpha, DI(HYDROXYETHYL)ETHER, [4,5,6,7-tetrabromo-2-(dimethylamino)-1H-benzimidazol-1-yl]acetic acid | 著者 | Papinutto, E, Franchin, C, Battistutta, R. | 登録日 | 2009-12-03 | 公開日 | 2010-11-17 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | ATP site-directed inhibitors of protein kinase CK2: an update. Curr Top Med Chem, 11, 2011
|
|
3GTA
| Structure of an ML-IAP/XIAP chimera bound to a peptidomimetic | 分子名称: | 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Baculoviral IAP repeat-containing 7, ... | 著者 | Franklin, M.C, Fairbrother, W.J, Cohen, F. | 登録日 | 2009-03-27 | 公開日 | 2010-03-09 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Antagonists of inhibitor of apoptosis proteins based on thiazole amide isosteres. Bioorg.Med.Chem.Lett., 20, 2010
|
|
3KXN
| Crystal structure of Z. mays CK2 kinase alpha subunit in complex with the inhibitor tetraiodobenzimidazole (K88) | 分子名称: | 4,5,6,7-tetraiodo-1H-benzimidazole, Casein kinase II subunit alpha | 著者 | Papinutto, E, Franchin, C, Battistutta, R. | 登録日 | 2009-12-03 | 公開日 | 2010-11-17 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | ATP site-directed inhibitors of protein kinase CK2: an update. Curr Top Med Chem, 11, 2011
|
|
3KP4
| |
3FNG
| Crystal structure of InhA bound to triclosan derivative | 分子名称: | 5-(cyclohexylmethyl)-2-(2,4-dichlorophenoxy)phenol, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Wang, F. | 登録日 | 2008-12-24 | 公開日 | 2009-01-20 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Triclosan Derivatives: Towards Potent Inhibitors of Drug-Sensitive and Drug-Resistant Mycobacterium tuberculosis. Chemmedchem, 4, 2009
|
|