2W5U

Flavodoxin from Helicobacter pylori in complex with the C3 inhibitor

Summary for 2W5U

• Entry DOI: 10.2210/pdb2w5u/pdb
• Related: 2BMV
• Descriptor: Flavodoxin, FLAVIN MONONUCLEOTIDE, [2-(5-amino-4-cyano-1H-pyrazol-1-yl)-5-(trifluoromethyl)phenyl](hydroxy)oxoammonium, ... (4 entities in total)
• Functional Keywords: drug discovery, electron transport, protein hinhibitor, fmn, transport, flavodoxin, flavoprotein
• Biological source: HELICOBACTER PYLORI
• Total number of polymer chains: 2
• Total formula weight: 36291.53

Authors

Cremades, N.,Perez-Dorado, I.,Hermoso, J.A.,Martinez-Julvez, M.,Sancho, J. (deposition date: 2008-12-12, release date: 2009-12-22, Last modification date: 2023-12-13)

• Primary citation: Cremades, N.,Velazquez-Campoy, A.,Martinez-Julvez, M.,Neira, J.L.,Perez-Dorado, I.,Hermoso, J.,Jimenez, P.,Lanas, A.,Hoffman, P.S.,Sancho, J.; Discovery of Specific Flavodoxin Inhibitors as Potential Therapeutic Agents Against Helicobacter Pylori Infection.; Acs Chem.Biol., 4:928-, 2009; PubMed: 19725577; DOI: 10.1021/CB900166Q

Experimental method

X-RAY DIFFRACTION (2.62 Å)