PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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4LCH	Crystal structure of the Pseudomonas aeruginosa LPXC/LPC-051 complex 分子名称: (betaS)-Nalpha-{4-[4-(4-aminophenyl)buta-1,3-diyn-1-yl]benzoyl}-N,beta-dihydroxy-beta-methyl-L-tyrosinamide, NITRATE ION, UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase, ... 著者 Lee, C.-J, Zhou, P. 登録日 2013-06-21 公開日 2013-08-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.596 Å) 主引用文献 Synthesis, Structure, and Antibiotic Activity of Aryl-Substituted LpxC Inhibitors. J.Med.Chem., 56, 2013
4DA6	Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in complex with ganciclovir 分子名称: 9-(1,3-DIHYDROXY-PROPOXYMETHANE)GUANINE, CHLORIDE ION, DIMETHYL SULFOXIDE, ... 著者 Martins, N.H, Giuseppe, P.O, Meza, A.N, Murakami, M.T. 登録日 2012-01-12 公開日 2012-09-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
4DJT	Crystal structure of a nuclear GTP-binding protein from Encephalitozoon cuniculi bound to GDP-Mg2+ 分子名称: GTP-binding nuclear protein GSP1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-02-02 公開日 2012-02-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of a nuclear GTP-binding protein from Encephalitozoon cuniculi bound to GDP-Mg2+ To be Published
4DAO	Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in complex with adenine 分子名称: ADENINE, GLYCEROL, Purine nucleoside phosphorylase deoD-type 著者 Giuseppe, P.O, Martins, N.H, Meza, A.N, Murakami, M.T. 登録日 2012-01-13 公開日 2012-09-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
4DK3	Structure of Editosome protein 分子名称: RNA-editing complex protein MP81, single domain antibody VHH 著者 Park, Y.-J, Hol, W. 登録日 2012-02-03 公開日 2012-07-04 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 The structure of the C-terminal domain of the largest editosome interaction protein and its role in promoting RNA binding by RNA-editing ligase L2. Nucleic Acids Res., 40, 2012
4DKA	Structure of Editosome protein 分子名称: RNA-editing complex protein MP81, SODIUM ION, single domain antibody VHH 著者 Park, Y.-J, Hol, W. 登録日 2012-02-03 公開日 2012-07-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 The structure of the C-terminal domain of the largest editosome interaction protein and its role in promoting RNA binding by RNA-editing ligase L2. Nucleic Acids Res., 40, 2012
4DN7	CRYSTAL STRUCTURE OF putative ABC transporter, ATP-binding protein from Methanosarcina mazei Go1 分子名称: ABC transporter, ATP-binding protein, PENTAETHYLENE GLYCOL 著者 Malashkevich, V.N, Bhosle, R, Toro, R, Seidel, R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2012-02-08 公開日 2012-02-22 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 CRYSTAL STRUCTURE OF putative ABC transporter, ATP-binding protein from Methanosarcina mazei Go1 To be Published
4DOJ	Crystal structure of BetP in outward-facing conformation 分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, CHLORIDE ION, CHOLINE ION, ... 著者 Perez, C, Ziegler, C. 登録日 2012-02-09 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Alternating-access mechanism in conformationally asymmetric trimers of the betaine transporter BetP. Nature, 490, 2012
4M0F	Structure of human acetylcholinesterase in complex with territrem B 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Cheung, J, Gary, E.N, Shiomi, K, Rosenberry, T.L. 登録日 2013-08-01 公開日 2013-10-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.304 Å) 主引用文献 Structures of human acetylcholinesterase bound to dihydrotanshinone I and territrem B show peripheral site flexibility. ACS Med Chem Lett, 4, 2013
4M4O	Crystal structure of the aptamer minE-lysozyme complex 分子名称: Lysozyme C, MAGNESIUM ION, RNA (59-MER), ... 著者 Malashkevich, V.N, Padlan, F.C, Toro, R, Girvin, M, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2013-08-07 公開日 2013-12-18 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of the aptamer minE-lysozyme complex to be published
4M21	Crystal Structure of small molecule acrylamide 11 covalently bound to K-Ras G12C 分子名称: 1-(4-{[(4,5-dichloro-2-methoxyphenyl)amino]acetyl}piperazin-1-yl)propan-1-one, GUANOSINE-5'-DIPHOSPHATE, K-Ras GTPase 著者 Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M. 登録日 2013-08-05 公開日 2013-11-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions. Nature, 503, 2013
4M7W	Crystal structure of purine nucleoside phosphorylase from Leptotrichia buccalis C-1013-b, NYSGRC Target 029767. 分子名称: PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type 著者 Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2013-08-12 公開日 2013-08-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of purine nucleoside phosphorylase from Leptotrichia buccalis C-1013-b, NYSGRC Target 029767. To be Published
4DUQ	The Structure of Ca2+-loaded S100A2 at 1.3A resolution 分子名称: CALCIUM ION, POLYETHYLENE GLYCOL (N=34), Protein S100-A2 著者 Koch, M, Fritz, G. 登録日 2012-02-22 公開日 2012-03-07 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 The structure of Ca2+-loaded S100A2 at 1.3- angstrom resolution. Febs J., 279, 2012
4DPF	BACE-1 in complex with a HEA-macrocyclic type inhibitor 分子名称: Beta-secretase 1, N-[(4S,8E,11S)-4-[(1R)-1-hydroxy-2-{[3-(propan-2-yl)benzyl]amino}ethyl]-2,13-dioxo-11-phenyl-6-oxa-3,12-diazabicyclo[12.3.1]octadeca-1(18),8,14,16-tetraen-16-yl]-N-methylmethanesulfonamide 著者 Lindberg, J, Borkakoti, N, Derbyshire, D. 登録日 2012-02-13 公開日 2012-07-11 最終更新日 2013-01-02 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Highly potent macrocyclic BACE-1 inhibitors incorporating a hydroxyethylamine core: design, synthesis and X-ray crystal structures of enzyme inhibitor complexes. Bioorg.Med.Chem., 20, 2012
4MCI	Crystal structure of uridine phosphorylase from vibrio fischeri es114 complexed with DMSO, NYSGRC Target 029520. 分子名称: DIMETHYL SULFOXIDE, SULFATE ION, Uridine phosphorylase 著者 Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2013-08-21 公開日 2013-09-04 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Crystal structure of uridine phosphorylase from vibrio fischeri es114 complexed with DMSO, NYSGRC Target 029520. To be Published
4MCV	Star 12 bound to analog-sensitive Src kinase 分子名称: (7S)-12-(4-aminobutyl)-7-(2-methylpropyl)-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one, Proto-oncogene tyrosine-protein kinase Src 著者 Lopez, M.S, Shokat, K.M. 登録日 2013-08-21 公開日 2013-11-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.73 Å) 主引用文献 Staurosporine-derived inhibitors broaden the scope of analog-sensitive kinase technology. J.Am.Chem.Soc., 135, 2013
4MB3	Crystal structure of E153Q mutant of cold-adapted chitinase from Moritella marina 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Chitinase 60, ... 著者 Malecki, P.H, Vorgias, C.E, Rypniewski, W. 登録日 2013-08-19 公開日 2014-03-19 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Crystal structures of substrate-bound chitinase from the psychrophilic bacterium Moritella marina and its structure in solution Acta Crystallogr.,Sect.D, 70, 2014
4D8L	Crystal structure of the 2-pyrone-4,6-dicarboxylic acid hydrolase from sphingomonas paucimobilis 分子名称: 2-pyrone-4,6-dicarbaxylate hydrolase 著者 Malashkevich, V.N, Toro, R, Bonanno, J, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2012-01-10 公開日 2012-01-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure and Catalytic Mechanism of LigI: Insight into the Amidohydrolase Enzymes of cog3618 and Lignin Degradation. Biochemistry, 51, 2012
4D8V	Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis at pH 4.2 分子名称: ADENINE, Purine nucleoside phosphorylase deoD-type, SULFATE ION 著者 Santos, C.R, Meza, A.N, Martins, N.H, Giuseppe, P.O, Murakami, M.T. 登録日 2012-01-11 公開日 2012-09-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
4D9J	Structure of a 16 nm protein cage designed by fusing symmetric oligomeric domains 分子名称: Designed 16nm tetrahedral protein cage containing Non-haem bromoperoxidase BPO-A2 and Matrix protein 1 著者 Lai, Y.-T, Cascio, D, Yeates, T.O. 登録日 2012-01-11 公開日 2012-06-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.92 Å) 主引用文献 Structure of a 16-nm cage designed by using protein oligomers. Science, 336, 2012
4LOG	The crystal structure of the orphan nuclear receptor PNR ligand binding domain fused with MBP 分子名称: Maltose ABC transporter periplasmic protein and NR2E3 protein chimeric construct 著者 Tan, M.E, Zhou, X.E, Soon, F.-F, Li, X, Li, J, Yong, E.-L, Melcher, K, Xu, H.E. 登録日 2013-07-12 公開日 2013-10-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The Crystal Structure of the Orphan Nuclear Receptor NR2E3/PNR Ligand Binding Domain Reveals a Dimeric Auto-Repressed Conformation. Plos One, 8, 2013
4LRZ	Crystal Structure of the E.coli DhaR(N)-DhaL complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PTS-dependent dihydroxyacetone kinase operon regulatory protein, ... 著者 Shi, R, McDonald, L, Cygler, M, Ekiel, I. 登録日 2013-07-21 公開日 2014-01-29 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 Coiled-Coil Helix Rotation Selects Repressing or Activating State of Transcriptional Regulator DhaR. Structure, 22, 2014
4D8O	Crystal Structure of the ankyrin-B ZU5-ZU5-UPA-DD tandem 分子名称: Ankyrin-2 著者 Wei, Z, Wang, C, Yu, C, Zhang, M. 登録日 2012-01-11 公開日 2012-03-28 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.203 Å) 主引用文献 Structure of the ZU5-ZU5-UPA-DD tandem of ankyrin-B reveals interaction surfaces necessary for ankyrin function Proc.Natl.Acad.Sci.USA, 109, 2012
4LST	Crystal structure of broadly and potently neutralizing antibody VRC01 in complex with HIV-1 clade C strain ZM176.66 gp120 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ENVELOPE GLYCOPROTEIN GP120 of HIV-1 clade C, HEAVY CHAIN OF ANTIBODY VRC01, ... 著者 Zhou, T, Moquin, S, Kwong, P.D. 登録日 2013-07-23 公開日 2013-08-21 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies. Immunity, 39, 2013
4LUD	Crystal Structure of HCK in complex with the fluorescent compound SKF86002 分子名称: 6-(4-fluorophenyl)-5-(pyridin-4-yl)-2,3-dihydroimidazo[2,1-b][1,3]thiazole, CALCIUM ION, CHLORIDE ION, ... 著者 Parker, L.J, Tanaka, A, Handa, N, Honda, K, Tomabechi, Y, Shirouzu, M, Yokoyama, S. 登録日 2013-07-25 公開日 2014-02-12 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Kinase crystal identification and ATP-competitive inhibitor screening using the fluorescent ligand SKF86002. Acta Crystallogr.,Sect.D, 70, 2014

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