4M0F

Structure of human acetylcholinesterase in complex with territrem B

Summary for 4M0F

• Entry DOI: 10.2210/pdb4m0f/pdb
• Related: 4M0E
• Descriptor: Acetylcholinesterase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, territrem B, ... (7 entities in total)
• Functional Keywords: acetylcholinesterase, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 121619.87

Authors

Cheung, J.,Gary, E.N.,Shiomi, K.,Rosenberry, T.L. (deposition date: 2013-08-01, release date: 2013-10-16, Last modification date: 2023-09-20)

• Primary citation: Cheung, J.,Gary, E.N.,Shiomi, K.,Rosenberry, T.L.; Structures of human acetylcholinesterase bound to dihydrotanshinone I and territrem B show peripheral site flexibility.; ACS Med Chem Lett, 4:1091-1096, 2013; PubMed: 24900610; DOI: 10.1021/ml400304w

Experimental method

X-RAY DIFFRACTION (2.304 Å)