PDB: 2897 件ウェブページステータス検索Chemie searchBIRD

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6V3G	Cryo-EM structure of Ca2+-free hsSlo1 channel 分子名称: Calcium-activated potassium channel subunit alpha-1 著者 Tao, X, MacKinnon, R. 登録日 2019-11-25 公開日 2019-12-25 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Molecular structures of the human Slo1 K + channel in complex with beta 4. Elife, 8, 2019
6V38	Cryo-EM structure of Ca2+-bound hsSlo1 channel 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, CHOLESTEROL, ... 著者 Tao, X, MacKinnon, R. 登録日 2019-11-25 公開日 2019-12-25 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Molecular structures of the human Slo1 K + channel in complex with beta 4. Elife, 8, 2019
2BKP	STRUCTURE ANALYSIS OF UNKNOWN FUNCTION PROTEIN 分子名称: HYPOTHETICAL PROTEIN PH0236, POTASSIUM ION 著者 Inagaki, E, Tahirov, T.H. 登録日 2005-02-18 公開日 2006-06-28 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Analysis of Putative Potassium Channel Related Protein from Pyrococcus Horikoshii To be Published
4J7C	KtrAB potassium transporter from Bacillus subtilis 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Ktr system potassium uptake protein A, Ktr system potassium uptake protein B, ... 著者 Vieira-Pires, R.S, Morais-Cabral, J.H. 登録日 2013-02-13 公開日 2013-04-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 The structure of the KtrAB potassium transporter Nature, 496, 2013
5J7E	hEAG PAS domain 分子名称: Potassium voltage-gated channel subfamily H member 1 著者 Xue, T, Juan, S, Xiaohong, Q. 登録日 2016-04-06 公開日 2016-05-04 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure of PAS domain from the hEAG Potassium Channel To Be Published
8ZYN	Cryo-EM Structure of inhibitor-free hERG Channel 分子名称: Potassium voltage-gated channel subfamily H member 2 著者 Miyashita, Y, Moriya, T, Kato, T, Kawasaki, M, Yasuda, Y, Adachi, N, Suzuki, K, Ogasawara, S, Saito, T, Senda, T, Murata, T. 登録日 2024-06-18 公開日 2024-09-18 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (3.27 Å) 主引用文献 Improved higher resolution cryo-EM structures reveal the binding modes of hERG channel inhibitors. Structure, 2024
8ZYP	Cryo-EM Structure of E-4031-bound hERG Channel 分子名称: Potassium voltage-gated channel subfamily H member 2, ~{N}-[4-[1-[2-(6-methylpyridin-2-yl)ethyl]piperidin-4-yl]carbonylphenyl]methanesulfonamide 著者 Miyashita, Y, Moriya, T, Kato, T, Kawasaki, M, Yasuda, Y, Adachi, N, Suzuki, K, Ogasawara, S, Saito, T, Senda, T, Murata, T. 登録日 2024-06-18 公開日 2024-09-18 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (3.19 Å) 主引用文献 Improved higher resolution cryo-EM structures reveal the binding modes of hERG channel inhibitors. Structure, 2024
7YIH	Human KCNH5 open state 分子名称: POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5 著者 Zhang, M.F. 登録日 2022-07-16 公開日 2023-04-05 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel. Nat Commun, 14, 2023
7YIJ	Human KCNH5 pore dilation but the non-conducting state 分子名称: POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5 著者 Zhang, M.F. 登録日 2022-07-16 公開日 2023-04-05 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel. Nat Commun, 14, 2023
7YID	Human KCNH5 closed state 1 分子名称: POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5 著者 Zhang, M.F. 登録日 2022-07-16 公開日 2023-04-05 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel. Nat Commun, 14, 2023
7YIF	Human KCNH5 pre-open state 1 分子名称: POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5 著者 Zhang, M.F. 登録日 2022-07-16 公開日 2023-04-05 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel. Nat Commun, 14, 2023
7YIG	Human KCNH5 pre-open state 2 分子名称: POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5 著者 Zhang, M.F. 登録日 2022-07-16 公開日 2023-04-05 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel. Nat Commun, 14, 2023
7YIE	Human KCNH5-closed state 2 分子名称: POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5 著者 Zhang, M.F. 登録日 2022-07-16 公開日 2023-04-05 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel. Nat Commun, 14, 2023
8IZY	Human KCNQ2-CaM in complex with HN37 分子名称: Potassium voltage-gated channel subfamily KQT member 2, methyl N-[4-[(4-fluorophenyl)methyl-prop-2-ynyl-amino]-2,6-dimethyl-phenyl]carbamate 著者 Ma, D, Li, X, Guo, J. 登録日 2023-04-09 公開日 2023-11-29 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Ligand activation mechanisms of human KCNQ2 channel. Nat Commun, 14, 2023
7RE5	Crystal Structure of The Tetramerization Domain (29-147) From Human Voltage-gated Potassium Channel Kv2.1 in P 41 21 2 Space Group 分子名称: Potassium voltage-gated channel subfamily B member 1, ZINC ION 著者 Xu, Z, Schnicker, N, Baker, S. 登録日 2021-07-12 公開日 2022-06-08 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Pentameric assembly of the Kv2.1 tetramerization domain. Acta Crystallogr D Struct Biol, 78, 2022
5U76	Chicken Slo2.2 in a closed conformation vitrified in the presence of 300 mM NaCl 分子名称: Potassium channel subfamily T member 1 著者 Hite, R.K, MacKinnon, R. 登録日 2016-12-11 公開日 2017-02-08 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.76 Å) 主引用文献 Structural Titration of Slo2.2, a Na(+)-Dependent K(+) Channel. Cell, 168, 2017
5U70	Chicken Slo2.2 in an open conformation vitrified in the presence of 300 mM NaCl 分子名称: Potassium channel subfamily T member 1 著者 Hite, R.K, MacKinnon, R. 登録日 2016-12-09 公開日 2017-02-08 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.76 Å) 主引用文献 Structural Titration of Slo2.2, a Na(+)-Dependent K(+) Channel. Cell, 168, 2017
7CR2	human KCNQ2 in complex with retigabine 分子名称: Potassium voltage-gated channel subfamily KQT member 2, ethyl N-[2-azanyl-4-[(4-fluorophenyl)methylamino]phenyl]carbamate 著者 Li, X, Lv, D, Wang, J, Ye, S, Guo, J. 登録日 2020-08-12 公開日 2020-09-16 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Molecular basis for ligand activation of the human KCNQ2 channel. Cell Res., 31, 2021
7CR0	human KCNQ2 in apo state 分子名称: Potassium voltage-gated channel subfamily KQT member 2 著者 Li, X, Lv, D, Wang, J, Ye, S, Guo, J. 登録日 2020-08-12 公開日 2020-09-16 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Molecular basis for ligand activation of the human KCNQ2 channel. Cell Res., 31, 2021
5U6O	Structure of the human HCN1 hyperpolarization-activated cyclic nucleotide-gated ion channel 分子名称: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 著者 Lee, C.-H, MacKinnon, R. 登録日 2016-12-08 公開日 2017-01-25 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structures of the Human HCN1 Hyperpolarization-Activated Channel. Cell, 168, 2017
6MIE	Solution NMR structure of the KCNQ1 voltage-sensing domain 分子名称: Potassium voltage-gated channel subfamily KQT member 1 著者 Taylor, K.C, Kuenze, G, Smith, J.A, Meiler, J, McFeeters, R.L, Sanders, C.R. 登録日 2018-09-19 公開日 2020-03-04 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structure and physiological function of the human KCNQ1 channel voltage sensor intermediate state. Elife, 9, 2020
4HPF	Structure of the human SLO3 gating ring 分子名称: Potassium channel subfamily U member 1 著者 Leonetti, M.D, Yuan, P, MacKinnon, R. 登録日 2012-10-23 公開日 2012-11-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Functional and structural analysis of the human SLO3 pH- and voltage-gated K+ channel. Proc.Natl.Acad.Sci.USA, 109, 2012
8WTZ	potassium outward rectifier channel SKOR 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Potassium channel SKOR 著者 Gao, X, Sun, T, Lu, Y, Jia, Y, Xu, X, Zhang, Y, Fu, P, Yang, G. 登録日 2023-10-19 公開日 2024-04-10 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural changes in the conversion of an Arabidopsis outward-rectifying K + channel into an inward-rectifying channel. Plant Commun., 5, 2024
2ZXE	Crystal structure of the sodium - potassium pump in the E2.2K+.Pi state 分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... 著者 Shinoda, T, Ogawa, H, Cornelius, F, Toyoshima, C. 登録日 2008-12-22 公開日 2009-05-19 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of the sodium - potassium pump at 2.4 A resolution Nature, 459, 2009
1UJL	Solution Structure of the HERG K+ channel S5-P extracellular linker 分子名称: Potassium voltage-gated channel subfamily H member 2 著者 Torres, A.M, Bansal, P.S, Sunde, M, Clarke, C.E, Bursill, J.A, Smith, D.J, Bauskin, A, Breit, S.N, Campbell, T.J, Alewood, P.F, Kuchel, P.W, Vandenberg, J.I. 登録日 2003-08-05 公開日 2003-11-04 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Structure of the HERG K+ channel S5P extracellular linker: role of an amphipathic alpha-helix in C-type inactivation. J.Biol.Chem., 278, 2003

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