8ZYN

Cryo-EM Structure of inhibitor-free hERG Channel

Summary for 8ZYN

Entry DOI	10.2210/pdb8zyn/pdb
EMDB information	60573
Descriptor	Potassium voltage-gated channel subfamily H member 2 (1 entity in total)
Functional Keywords	drug toxicity, potassium ion, herg, cryo-em, membrane protein, transport protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	367168.34
Authors	Miyashita, Y.,Moriya, T.,Kato, T.,Kawasaki, M.,Yasuda, Y.,Adachi, N.,Suzuki, K.,Ogasawara, S.,Saito, T.,Senda, T.,Murata, T. (deposition date: 2024-06-18, release date: 2024-09-18, Last modification date: 2024-10-09)
Primary citation	Miyashita, Y.,Moriya, T.,Kato, T.,Kawasaki, M.,Yasuda, S.,Adachi, N.,Suzuki, K.,Ogasawara, S.,Saito, T.,Senda, T.,Murata, T. Improved higher resolution cryo-EM structures reveal the binding modes of hERG channel inhibitors. Structure, 2024 Cited by PubMed: 39321803 DOI: 10.1016/j.str.2024.08.021 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.27 Å)

Structure validation