8ZYN

Cryo-EM Structure of inhibitor-free hERG Channel

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Potassium voltage-gated channel subfamily H member 2	polymer	820	91792.1	4	UniProt (Q12809) Pfam (PF13426) Pfam (PF00520) Pfam (PF07885) Pfam (PF00027)	Homo sapiens (human)	Eag homolog,Ether-a-go-go-related gene potassium channel 1,ERG-1,Eag-related protein 1,Ether-a-go-go-related protein 1,H-ERG,hERG-1,hERG1,Voltage-gated potassium channel subunit Kv11.1

Sequence modifications

A, B, C, D: 211 - 350 (UniProt: Q12809)
A, B, C, D: 351 - 870 (UniProt: Q12809)
A, B, C, D: 871 - 1024 (UniProt: Q12809)

PDB	External Database	Details
Leu 1025	-	expression tag
Glu 1026	-	expression tag
Val 1027	-	expression tag
Leu 1028	-	expression tag
Phe 1029	-	expression tag
Gln 1030	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	367168.3
All*	Total formula weight	367168.3

*Water molecules are not included.