7NIV
 
 | | Nanodisc reconstituted human ABCB4 in complex with 4B1-Fab and QA2-Fab (phosphatidylcholine-bound, occluded conformation) | | 分子名称: | 1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 4B1 Fab-fragment light chain, CHOLESTEROL, ... | | 著者 | Nosol, K, Locher, K.P. | | 登録日 | 2021-02-14 | | 公開日 | 2021-08-25 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structures of ABCB4 provide insight into phosphatidylcholine translocation.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7NIW
 | | Nanodisc reconstituted human ABCB4 in complex with 4B1-Fab (posaconazole-bound, inward-open conformation) | | 分子名称: | 1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 4B1 Fab-fragment heavy chain, 4B1 Fab-fragment light chain, ... | | 著者 | Nosol, K, Locher, K.P. | | 登録日 | 2021-02-14 | | 公開日 | 2021-08-25 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structures of ABCB4 provide insight into phosphatidylcholine translocation.
Proc.Natl.Acad.Sci.USA, 118, 2021
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8IZ8
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8IZ7
 | | cryo-EM structure of sulindac-bound hMRP4 | | 分子名称: | ATP-binding cassette sub-family C member 4, [(1Z)-5-fluoro-2-methyl-1-{4-[methylsulfinyl]benzylidene}-1H-inden-3-yl]acetic acid | | 著者 | Liu, Z.M, Huang, Y. | | 登録日 | 2023-04-06 | | 公開日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | cryo-EM structure of sulindac-bound hMRP4
To Be Published
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1BLN
 | | ANTI-P-GLYCOPROTEIN FAB MRK-16 | | 分子名称: | PROTEIN (MONOCLONAL ANTIBODY MRK-16 (HEAVY CHAIN)), PROTEIN (MONOCLONAL ANTIBODY MRK-16 (LIGHT CHAIN)) | | 著者 | Vasudevan, S, Tsuruo, T, Rose, D.R. | | 登録日 | 1998-07-16 | | 公開日 | 1998-10-28 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Mode of binding of anti-P-glycoprotein antibody MRK-16 to its antigen. A crystallographic and molecular modeling study.
J.Biol.Chem., 273, 1998
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6ZME
 | | SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complex | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | | 著者 | Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | | 登録日 | 2020-07-02 | | 公開日 | 2020-08-12 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Science, 369, 2020
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2AP2
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5T83
 | | Structure of a guanidine-I riboswitch from S. acidophilus | | 分子名称: | GUANIDINE, IRIDIUM HEXAMMINE ION, MAGNESIUM ION, ... | | 著者 | Reiss, C.W, Xiong, Y, Strobel, S.A. | | 登録日 | 2016-09-06 | | 公開日 | 2017-01-11 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | Structural Basis for Ligand Binding to the Guanidine-I Riboswitch.
Structure, 25, 2017
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7JU3
 | | MtrR bound to the mtrCDE operator from Neisseria gonorrhoeae | | 分子名称: | CALCIUM ION, DNA (5'-D(*AP*CP*AP*TP*AP*CP*AP*CP*GP*AP*TP*TP*GP*CP*AP*CP*GP*GP*AP*TP*A)-3'), DNA (5'-D(*TP*AP*TP*CP*CP*GP*TP*GP*CP*AP*AP*TP*CP*GP*TP*GP*TP*AP*TP*GP*T)-3'), ... | | 著者 | Beggs, G.A, Shafer, W.M, Brennan, R.G. | | 登録日 | 2020-08-19 | | 公開日 | 2021-03-24 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structures of Neisseria gonorrhoeae MtrR-operator complexes reveal molecular mechanisms of DNA recognition and antibiotic resistance-conferring clinical mutations.
Nucleic Acids Res., 49, 2021
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7JNP
 | | MtrR bound to the rpoH operator from Neisseria gonorrhoeae | | 分子名称: | CALCIUM ION, DNA (5'-D(*TP*AP*CP*AP*TP*AP*CP*GP*TP*GP*GP*TP*TP*GP*TP*AP*TP*GP*TP*AP*A)-3'), DNA (5'-D(*TP*TP*AP*CP*AP*TP*AP*CP*AP*AP*CP*CP*AP*CP*GP*TP*AP*TP*GP*TP*A)-3'), ... | | 著者 | Beggs, G.A, Shafer, W.M, Brennan, R.G. | | 登録日 | 2020-08-05 | | 公開日 | 2021-03-24 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structures of Neisseria gonorrhoeae MtrR-operator complexes reveal molecular mechanisms of DNA recognition and antibiotic resistance-conferring clinical mutations.
Nucleic Acids Res., 49, 2021
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6ZVJ
 | | Structure of a human ABCE1-bound 43S pre-initiation complex - State II | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | | 著者 | Kratzat, H, Mackens-Kiani, T, Ameismeier, A, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | | 登録日 | 2020-07-24 | | 公開日 | 2020-10-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
Embo J., 40, 2021
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7A09
 | | Structure of a human ABCE1-bound 43S pre-initiation complex - State III | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | | 著者 | Kratzat, H, Mackens-Kiani, T, Ameismeier, A, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | | 登録日 | 2020-08-07 | | 公開日 | 2020-10-14 | | 最終更新日 | 2021-01-13 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
Embo J., 40, 2021
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4ESF
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4ESB
 | | Crystal structure of PadR-like transcriptional regulator (BC4206) from Bacillus cereus strain ATCC 14579 | | 分子名称: | GLYCEROL, SULFATE ION, Transcriptional regulator, ... | | 著者 | Fibriansah, G, Kovacs, A.T, Kuipers, O.P, Thunnissen, A.M.W.H. | | 登録日 | 2012-04-23 | | 公開日 | 2012-12-05 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal Structures of Two Transcriptional Regulators from Bacillus cereus Define the Conserved Structural Features of a PadR Subfamily.
Plos One, 7, 2012
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6TV1
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6MH4
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6MH5
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4U8D
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6WXI
 | | Colicin E1 fragment in nanodisc-embedded TolC | | 分子名称: | Outer membrane protein TolC | | 著者 | Kaelber, J.T, Budiardjo, S.J, Firlar, E, Ikujuni, A.P, Slusky, J.S.G. | | 登録日 | 2020-05-10 | | 公開日 | 2021-05-12 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | | 主引用文献 | Colicin E1 opens its hinge to plug TolC.
Elife, 11, 2022
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6WXH
 | | Colicin E1 fragment in nanodisc-embedded TolC | | 分子名称: | Colicin-E1, Outer membrane protein TolC | | 著者 | Kaelber, J.T, Budiardjo, S.J, Firlar, E, Case, D.A, Ikujuni, A.P, Slusky, J.S.G. | | 登録日 | 2020-05-10 | | 公開日 | 2021-05-12 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | | 主引用文献 | Colicin E1 opens its hinge to plug TolC.
Elife, 11, 2022
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8QOI
 | | Structure of the human 80S ribosome at 1.9 A resolution - the molecular role of chemical modifications and ions in RNA | | 分子名称: | 18S rRNA (1740-MER), 28S rRNA (3773-MER), 40S ribosomal protein S10, ... | | 著者 | Holvec, S, Barchet, C, Frechin, L, Hazemann, I, von Loeffelholz, O, Klaholz, B.P. | | 登録日 | 2023-09-29 | | 公開日 | 2024-06-12 | | 最終更新日 | 2024-08-28 | | 実験手法 | ELECTRON MICROSCOPY (1.9 Å) | | 主引用文献 | The structure of the human 80S ribosome at 1.9 angstrom resolution reveals the molecular role of chemical modifications and ions in RNA.
Nat.Struct.Mol.Biol., 31, 2024
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6ABT
 | | Crystal structure of transcription factor from Listeria monocytogenes | | 分子名称: | PadR family transcriptional regulator | | 著者 | Lee, C, Hong, M. | | 登録日 | 2018-07-23 | | 公開日 | 2019-06-05 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure-based molecular characterization and regulatory mechanism of the LftR transcription factor from Listeria monocytogenes: Conformational flexibilities and a ligand-induced regulatory mechanism.
Plos One, 14, 2019
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6ABQ
 | | Crystal structure of transcription factor from Listeria monocytogenes | | 分子名称: | CHLORIDE ION, PadR family transcriptional regulator | | 著者 | Lee, C, Hong, M. | | 登録日 | 2018-07-23 | | 公開日 | 2019-06-05 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure-based molecular characterization and regulatory mechanism of the LftR transcription factor from Listeria monocytogenes: Conformational flexibilities and a ligand-induced regulatory mechanism.
Plos One, 14, 2019
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6ZTB
 | | Crystal Structure of human P-Cadherin EC1_EC2 | | 分子名称: | CALCIUM ION, Cadherin-3, SODIUM ION | | 著者 | Rondeau, J.M, Lehmann, S. | | 登録日 | 2020-07-17 | | 公開日 | 2021-05-05 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | PCA062, a P-cadherin Targeting Antibody-Drug Conjugate, Displays Potent Antitumor Activity Against P-cadherin-expressing Malignancies.
Mol.Cancer Ther., 20, 2021
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6ZTF
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