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3ZKB
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CRYSTAL STRUCTURE OF THE ATPASE REGION OF Mycobacterium tuberculosis GyrB WITH AMPPNP
分子名称: DNA GYRASE SUBUNIT B, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Agrawal, A, Roue, M, Spitzfaden, C, Petrella, S, Aubry, A, Volker, C, Mossakowska, D, Hann, M, Bax, B, Mayer, C.
登録日2013-01-22
公開日2013-09-18
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Mycobacterium Tuberculosis DNA Gyrase ATPase Domain Structures Suggest a Dissociative Mechanism that Explains How ATP Hydrolysis is Coupled to Domain Motion.
Biochem.J., 456, 2013
1GCB
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GAL6, YEAST BLEOMYCIN HYDROLASE DNA-BINDING PROTEASE (THIOL)
分子名称: GAL6 HG (EMTS) DERIVATIVE, GLYCEROL, MERCURY (II) ION, ...
著者Joshua-Tor, L, Xu, H.E, Johnston, S.A, Rees, D.C.
登録日1995-07-18
公開日1995-10-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of a conserved protease that binds DNA: the bleomycin hydrolase, Gal6.
Science, 269, 1995
3BV0
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Crystal Structure of PLP Bound 7,8-Diaminopelargonic Acid Synthase in Mycobacterium Tuberculosis
分子名称: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, PYRIDOXAL-5'-PHOSPHATE
著者Dey, S, Sacchettini, J.C.
登録日2008-01-04
公開日2008-02-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Structural characterization of the Mycobacterium tuberculosis biotin biosynthesis enzymes 7,8-diaminopelargonic acid synthase and dethiobiotin synthetase .
Biochemistry, 49, 2010
4RPI
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Crystal Structure of Nicotinate Mononucleotide Adenylyltransferase from Mycobacterium tuberculosis
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, nicotinate-nucleotide adenylyltransferase
著者Rodionova, I, Zuccola, H, Sorci, L, Aleshin, A.E, Kazanov, M, Sergienko, E, Rubin, E, Locher, C, Osterman, A.
登録日2014-10-30
公開日2015-01-28
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.417 Å)
主引用文献Mycobacterial nicotinate mononucleotide adenylyltransferase: structure, mechanism, and implications for drug discovery.
J. Biol. Chem., 290, 2015
4FEH
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Mycobacterium tuberculosis DprE1 - hexagonal crystal form
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, oxidoreductase DprE1
著者Batt, S.M, Besra, G.S, Futterer, K.
登録日2012-05-30
公開日2012-07-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.035 Å)
主引用文献Structural basis of inhibition of Mycobacterium tuberculosis DprE1 by benzothiazinone inhibitors.
Proc.Natl.Acad.Sci.USA, 109, 2012
4FF6
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Mycobacterium tuberculosis DprE1 in complex with CT325 - monoclinic crystal form
分子名称: 3-(hydroxyamino)-N-[(1R)-1-phenylethyl]-5-(trifluoromethyl)benzamide, FLAVIN-ADENINE DINUCLEOTIDE, IMIDAZOLE, ...
著者Batt, S.M, Besra, G.S, Futterer, K.
登録日2012-05-31
公開日2012-07-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis of inhibition of Mycobacterium tuberculosis DprE1 by benzothiazinone inhibitors.
Proc.Natl.Acad.Sci.USA, 109, 2012
4CGE
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Crystal structure of Mycobacterium tuberculosis Resuscitation promoting factor E
分子名称: RESUSCITATION-PROMOTING FACTOR RPFE
著者Mavrici, D, Prigozhin, D.M, Alber, T.
登録日2013-11-23
公開日2014-02-05
最終更新日2014-04-02
実験手法X-RAY DIFFRACTION (2.756 Å)
主引用文献Mycobacterium Tuberculosis Rpfe Crystal Structure Reveals a Positively Charged Catalytic Cleft.
Protein Sci., 23, 2014
4IF7
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Mycobacterium Tuberculosis Methionine aminopeptidase Type 1c in complex with homocysteine-methyl disulfide
分子名称: (2S)-2-amino-4-(methyldisulfanyl)butanoic acid, COBALT (II) ION, Methionine aminopeptidase 2
著者Reddi, R, Gumpena, R, Kishor, C, Addlagatta, A.
登録日2012-12-14
公開日2013-12-18
最終更新日2019-11-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents
Febs J., 281, 2014
4IDY
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Mycobacterium Tuberculosis Methionine aminopeptidase Type 1c in complex with 2-hydroxyethyl disulfide
分子名称: 2-HYDROXYETHYL DISULFIDE, Methionine aminopeptidase 2, POTASSIUM ION
著者Reddi, R, Gumpena, R, Kishor, C, Addlagatta, A.
登録日2012-12-13
公開日2013-12-18
最終更新日2015-02-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents
Febs J., 281, 2014
4FFA
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Sulfatase from Mycobacterium tuberculosis
分子名称: NITRATE ION, Rv3406 alkyl sulfatase
著者Sogi, K.M, Gartner, Z.J, Breidenbach, M.A, Bertozzi, C.R.
登録日2012-05-31
公開日2013-06-05
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mycobacterium tuberculosis Rv3406 Is a Type II Alkyl Sulfatase Capable of Sulfate Scavenging.
Plos One, 8, 2013
4FDN
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Mycobacterium tuberculosis DprE1 in complex with CT325 - hexagonal crystal form
分子名称: 3-(hydroxyamino)-N-[(1R)-1-phenylethyl]-5-(trifluoromethyl)benzamide, FLAVIN-ADENINE DINUCLEOTIDE, oxidoreductase DprE1
著者Batt, S.M, Besra, G.S, Futterer, K.
登録日2012-05-29
公開日2012-07-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of inhibition of Mycobacterium tuberculosis DprE1 by benzothiazinone inhibitors.
Proc.Natl.Acad.Sci.USA, 109, 2012
4FDP
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BU of 4fdp by Molmil
Mycobacterium tuberculosis DprE1 - monoclinic crystal form
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, IMIDAZOLE, oxidoreductase DprE1
著者Batt, S.M, Besra, G.S, Futterer, K.
登録日2012-05-29
公開日2012-07-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Structural basis of inhibition of Mycobacterium tuberculosis DprE1 by benzothiazinone inhibitors.
Proc.Natl.Acad.Sci.USA, 109, 2012
4FDO
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BU of 4fdo by Molmil
Mycobacterium tuberculosis DprE1 in complex with CT319
分子名称: 3-nitro-N-[(1R)-1-phenylethyl]-5-(trifluoromethyl)benzamide, FLAVIN-ADENINE DINUCLEOTIDE, oxidoreductase DprE1
著者Batt, S.M, Besra, G.S, Futterer, K.
登録日2012-05-29
公開日2012-07-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.403 Å)
主引用文献Structural basis of inhibition of Mycobacterium tuberculosis DprE1 by benzothiazinone inhibitors.
Proc.Natl.Acad.Sci.USA, 109, 2012
3CXV
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BU of 3cxv by Molmil
Crystal structure of the Cytochrome P450 CYP121 A233G mutant from Mycobacterium tuberculosis
分子名称: Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
著者Leys, D.
登録日2008-04-25
公開日2008-09-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Characterization of active site structure in CYP121. A cytochrome P450 essential for viability of Mycobacterium tuberculosis H37Rv.
J.Biol.Chem., 283, 2008
2VZW
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BU of 2vzw by Molmil
X-ray structure of the heme-bound GAF domain of sensory histidine kinase DosT of Mycobacterium tuberculosis
分子名称: ACETATE ION, OXYGEN MOLECULE, PROBABLE HISTIDINE KINASE RESPONSE REGULATOR, ...
著者Podust, L.M, Ioanoviciu, A, Ortiz de Montellano, P.R.
登録日2008-08-06
公開日2009-03-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献2.3 A X-Ray Structure of the Heme-Bound Gaf Domain of Sensory Histidine Kinase Dost of Mycobacterium Tuberculosis.
Biochemistry, 47, 2008
3QUO
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Crystal structure of fosfomycin resistance kinase FomA from Streptomyces wedmorensis complexed with ATP and fosfomycin
分子名称: ADENOSINE-5'-TRIPHOSPHATE, FOSFOMYCIN, FomA protein
著者Pakhomova, S, Bartlett, S.G, Doerner, P.A, Newcomer, M.E.
登録日2011-02-24
公開日2011-07-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Structural and biochemical insights into the mechanism of fosfomycin phosphorylation by fosfomycin resistance kinase FomA.
Biochemistry, 50, 2011
4Q6U
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BU of 4q6u by Molmil
Crystal structure of a putative uncharacterized protein from Mycobacterium tuberculosis
分子名称: PENTAETHYLENE GLYCOL, Uncharacterized protein
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2014-04-23
公開日2014-06-18
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Mycobacterium tuberculosis Rv3651 is a triple sensor-domain protein.
Protein Sci., 27, 2018
2WM5
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X-ray structure of the substrate-free Mycobacterium tuberculosis cytochrome P450 CYP124
分子名称: PROTOPORPHYRIN IX CONTAINING FE, PUTATIVE CYTOCHROME P450 124
著者Johnston, J.B, Kells, P.M, Podust, L.M, Ortiz de Montellano, P.R.
登録日2009-06-30
公開日2009-10-06
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Biochemical and structural characterization of CYP124: a methyl-branched lipid omega-hydroxylase from Mycobacterium tuberculosis.
Proc. Natl. Acad. Sci. U.S.A., 106, 2009
2WM4
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X-ray structure of Mycobacterium tuberculosis cytochrome P450 CYP124 in complex with phytanic acid
分子名称: (3R,7S,11S)-3,7,11,15-tetramethylhexadecanoic acid, CALCIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Johnston, J.B, Kells, P.M, Podust, L.M, Ortiz de Montellano, P.R.
登録日2009-06-30
公開日2009-10-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Biochemical and structural characterization of CYP124: a methyl-branched lipid omega-hydroxylase from Mycobacterium tuberculosis.
Proc. Natl. Acad. Sci. U.S.A., 106, 2009
2YW6
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Structural studies of N terminal deletion mutant of Dps from Mycobacterium smegmatis
分子名称: DNA protection during starvation protein
著者Roy, S, Saraswathi, R, Gupta, S, Sekar, K, Chatterji, D, Vijayan, M.
登録日2007-04-19
公開日2007-07-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Role of N and C-terminal Tails in DNA Binding and Assembly in Dps: Structural Studies of Mycobacterium smegmatis Dps Deletion Mutants
J.Mol.Biol., 370, 2007
2ZW4
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BU of 2zw4 by Molmil
Crystal structure of bleomycin N-acetyltransferase complexed with coenzyme A in the orthorhombic crystal
分子名称: Bleomycin acetyltransferase, COENZYME A, SULFATE ION
著者Oda, K, Matoba, Y, Sugiyama, M.
登録日2008-12-01
公開日2009-11-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Catalytic mechanism of bleomycin N-acetyltransferase proposed on the basis of its crystal structure.
J.Biol.Chem., 285, 2010
1D17
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DNA-NOGALAMYCIN INTERACTIONS
分子名称: DNA (5'-D(*(5CM)P*GP*TP*AP*(5CM)P*G)-3'), NOGALAMYCIN
著者Egli, M, Williams, L.D, Frederick, C.A, Rich, A.
登録日1990-08-08
公開日1991-07-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献DNA-nogalamycin interactions.
Biochemistry, 30, 1991
2ZW5
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Crystal structure of bleomycin N-acetyltransferase complexed with coenzyme A in the trigonal crystal
分子名称: Bleomycin acetyltransferase, COENZYME A
著者Oda, K, Matoba, Y, Sugiyama, M.
登録日2008-12-01
公開日2009-11-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Catalytic mechanism of bleomycin N-acetyltransferase proposed on the basis of its crystal structure.
J.Biol.Chem., 285, 2010
3UOF
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BU of 3uof by Molmil
Mycobacterium tuberculosis bacterioferritin, BfrA
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bacterioferritin, FE (III) ION, ...
著者McMath, L.M, Goulding, C.W, TB Structural Genomics Consortium (TBSGC)
登録日2011-11-16
公開日2012-11-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.902 Å)
主引用文献Mycobacterium tuberculosis bacterioferritin, BfrA
To be Published
7CU9
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Crystal structure of the soluble domain of TiME protein from Mycobacterium smegmatis
分子名称: GLYCEROL, MAGNESIUM ION, Tube-forming protein in Mycobacterial Envelpe, ...
著者Gong, W, Cai, X, Liu, L, Wen, C.
登録日2020-08-21
公開日2021-08-25
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Identification and architecture of a putative secretion tube across mycobacterial outer envelope.
Sci Adv, 7, 2021

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