8F30
 
 | | LSD1-CoREST in complex with AW2, long soaking | | 分子名称: | Lysine-specific histone demethylase 1A, REST corepressor 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2R,3S,4S)-5-{5-[3-([1,1'-biphenyl]-4-yl)propanoyl]-7,8-dimethyl-2,4-dioxo-1,3,4,5-tetrahydrobenzo[g]pteridin-10(2H)-yl}-2,3,4-trihydroxypentyl dihydrogen diphosphate (non-preferred name) | | 著者 | Caroli, J, Mattevi, A. | | 登録日 | 2022-11-09 | | 公開日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Distal drug resistance mutations promote covalent inhibitor-adduct Grob fragmentation in LSD1
to be published
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8F2Z
 | | LSD1-CoREST in complex with AW2, short soaking | | 分子名称: | Lysine-specific histone demethylase 1A, REST corepressor 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2R,3S,4S)-5-[(1R,3S,3aS,13R)-3-([1,1'-biphenyl]-4-yl)-1-hydroxy-10,11-dimethyl-4,6-dioxo-2,3,5,6-tetrahydro-1H-benzo[g]pyrrolo[2,1-e]pteridin-8(4H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate (non-preferred name) | | 著者 | Caroli, J, Mattevi, A. | | 登録日 | 2022-11-09 | | 公開日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Distal drug resistance mutations promote covalent inhibitor-adduct Grob fragmentation in LSD1
to be published
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8F28
 | | Lysozyme Structures from Single-Entity Crystallization Method NanoAC | | 分子名称: | ACETATE ION, CHLORIDE ION, Lysozyme C, ... | | 著者 | Yang, R, Sankaran, B, Ogbonna, E, Wang, G. | | 登録日 | 2022-11-07 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | A Single-Entity Method for Actively Controlled Nucleation and High-Quality Protein Crystal Synthesis.
Anal.Chem., 95, 2023
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8F1G
 | | Crystal structure of human WDR5 in complex with compound WM662 | | 分子名称: | (2S)-2-({(2S)-3-(3'-chloro[1,1'-biphenyl]-4-yl)-1-oxo-1-[(1H-tetrazol-5-yl)amino]propan-2-yl}oxy)propanoic acid, GLYCEROL, SULFATE ION, ... | | 著者 | Liu, H. | | 登録日 | 2022-11-05 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Discovery of Potent Small-Molecule Inhibitors of WDR5-MYC Interaction.
Acs Chem.Biol., 18, 2023
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8EW1
 | | Structure of Bacple_01703-E145L | | 分子名称: | ACETATE ION, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Ulaganathan, T, Cygler, M. | | 登録日 | 2022-10-21 | | 公開日 | 2023-05-10 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The porphyran degradation system of the human gut microbiota is complete, phylogenetically diverse and geographically structured across Asian populations
Biorxiv, 2023
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8EVJ
 | | CX3CR1 nucleosome bound PU.1 and C/EBPa | | 分子名称: | DNA (167-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... | | 著者 | Guan, R, Bai, Y, Lian, T. | | 登録日 | 2022-10-20 | | 公開日 | 2023-11-01 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural mechanism of synergistic targeting of the CX3CR1 nucleosome by PU.1 and C/EBP alpha.
Nat.Struct.Mol.Biol., 31, 2024
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8EVI
 | | CX3CR1 nucleosome and PU.1 complex containing disulfide bond mutations | | 分子名称: | DNA (167-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... | | 著者 | Lian, T, Guan, R, Bai, Y. | | 登録日 | 2022-10-20 | | 公開日 | 2023-11-01 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (2.64 Å) | | 主引用文献 | Structural mechanism of synergistic targeting of the CX3CR1 nucleosome by PU.1 and C/EBP alpha.
Nat.Struct.Mol.Biol., 31, 2024
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8EVH
 | | CX3CR1 nucleosome and wild type PU.1 complex | | 分子名称: | DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... | | 著者 | Lian, T, Guan, R, Bai, Y. | | 登録日 | 2022-10-20 | | 公開日 | 2023-11-01 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | | 主引用文献 | Structural mechanism of synergistic targeting of the CX3CR1 nucleosome by PU.1 and C/EBP alpha.
Nat.Struct.Mol.Biol., 31, 2024
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8EVG
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8EUJ
 | | Class2 of the INO80-Nucleosome complex | | 分子名称: | DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ... | | 著者 | Wu, H, Munoz, E, Gourdet, M, Narlikar, G, Cheng, Y.F. | | 登録日 | 2022-10-18 | | 公開日 | 2023-07-12 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.36 Å) | | 主引用文献 | Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility.
Science, 381, 2023
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8EUE
 | | Class1 of the INO80-Nucleosome complex | | 分子名称: | DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ... | | 著者 | Wu, H, Munoz, E, Gourdet, M, Narlikar, G, Cheng, Y.F. | | 登録日 | 2022-10-18 | | 公開日 | 2023-07-12 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | | 主引用文献 | Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility.
Science, 381, 2023
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8EU2
 | | Class3 of the INO80-Hexasome complex | | 分子名称: | DNA (110-MER), Histone H2A type 1, Histone H2B 1.1, ... | | 著者 | Wu, H, Munoz, E, Gourdet, M, Cheng, Y.F, Narlikar, G. | | 登録日 | 2022-10-18 | | 公開日 | 2023-07-12 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | | 主引用文献 | Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility.
Science, 381, 2023
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8ETV
 | | Class2 of the INO80-Hexasome complex | | 分子名称: | DNA (110-MER), Histone H2A type 1, Histone H2B 1.1, ... | | 著者 | Wu, H, Munoz, E, Gourdet, M, Cheng, Y.F, Narlikar, G. | | 登録日 | 2022-10-17 | | 公開日 | 2023-07-12 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | | 主引用文献 | Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility.
Science, 381, 2023
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8ETT
 | | Class1 of the INO80-Hexasome complex | | 分子名称: | DNA (110-MER), Histone H2A type 1, Histone H2B 1.1, ... | | 著者 | Wu, H, Munoz, E, Gourdet, M, Cheng, Y.F, Narlikar, G. | | 登録日 | 2022-10-17 | | 公開日 | 2023-07-12 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (6.68 Å) | | 主引用文献 | Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility.
Science, 381, 2023
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8ETB
 | | the crystal structure of a rationally designed zinc sensor based on maltose binding protein - Zn binding conformation | | 分子名称: | ACETATE ION, ZINC ION, Zinc Sensor protein | | 著者 | Zhao, Z, Zhou, M, Zemerov, S.D, Marmorstein, R, Dmochowski, I.J. | | 登録日 | 2022-10-16 | | 公開日 | 2023-03-22 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Rational design of a genetically encoded NMR zinc sensor.
Chem Sci, 14, 2023
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8ESX
 | | HIV protease in complex with benzoxaborolone analog of darunavir | | 分子名称: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | | 著者 | Windsor, I.W, Graham, B.J, Raines, R.T. | | 登録日 | 2022-10-15 | | 公開日 | 2023-02-08 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Inhibition of HIV-1 Protease by a Boronic Acid with High Oxidative Stability.
Acs Med.Chem.Lett., 14, 2023
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8ESC
 | | Structure of the Yeast NuA4 Histone Acetyltransferase Complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin-related protein 4, ... | | 著者 | Patel, A.B, Zukin, S.A, Nogales, E. | | 登録日 | 2022-10-13 | | 公開日 | 2022-11-16 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structure and flexibility of the yeast NuA4 histone acetyltransferase complex.
Elife, 11, 2022
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8EPV
 | | 2.2 A crystal structure of the lipocalin cat allergen Fel d 7 | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Fel d 7 allergen, ... | | 著者 | Min, J, Pedersen, L.C, Geoffrey, M.A. | | 登録日 | 2022-10-06 | | 公開日 | 2023-04-05 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Structural and ligand binding analysis of the pet allergens Can f 1 and Fel d 7.
Front Allergy, 4, 2023
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8EP4
 | | Structure of Bacple_01703 | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, CALCIUM ION, ... | | 著者 | Ulaganathan, T, Cygler, M. | | 登録日 | 2022-10-05 | | 公開日 | 2022-11-09 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | The porphyran degradation system of the human gut microbiota is complete, phylogenetically diverse and geographically structured across Asian populations
Biorxiv, 2023
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8EMI
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8EMG
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8ELH
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8ELG
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8EIM
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8EHN
 | | PRRSV-1 PLP2 domain | | 分子名称: | ACETATE ION, Papain-like protease 2, ZINC ION | | 著者 | Bailey-Elkin, B.A, Mark, B.L. | | 登録日 | 2022-09-14 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-01-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Demonstrating the importance of porcine reproductive and respiratory syndrome virus papain-like protease 2 deubiquitinating activity in viral replication by structure-guided mutagenesis.
Plos Pathog., 19, 2023
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