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8FZQ
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Dehosphorylated, ATP-bound human cystic fibrosis transmembrane conductance regulator (CFTR)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION
著者Levring, J, Terry, D.S, Kilic, Z, Fitzgerald, G.A, Blanchard, S.C, Chen, J.
登録日2023-01-29
公開日2023-03-29
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献CFTR function, pathology and pharmacology at single-molecule resolution.
Nature, 616, 2023
8DYP
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BU of 8dyp by Molmil
Crystal structure of human cystine transporter cystinosin
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Cystinosin, Nanobody P10, ...
著者Guo, X, Feng, L.
登録日2022-08-04
公開日2022-11-16
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structure and mechanism of human cystine exporter cystinosin.
Cell, 185, 2022
7D87
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BU of 7d87 by Molmil
Crystal Structure of zebrafish PHF14-PZP in complex with H3(1-25)
分子名称: CALCIUM ION, Gene for histone H3 (germline gene), PHD finger protein 14, ...
著者Li, H, Zheng, S.
登録日2020-10-07
公開日2021-07-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Molecular basis for bipartite recognition of histone H3 by the PZP domain of PHF14.
Nucleic Acids Res., 49, 2021
4M7A
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BU of 4m7a by Molmil
Crystal structure of Lsm2-8 complex bound to the 3' end sequence of U6 snRNA
分子名称: U6 snRNA, U6 snRNA-associated Sm-like protein LSm2, U6 snRNA-associated Sm-like protein LSm3, ...
著者Zhou, L, Hang, J, Zhou, Y, Wan, R, Lu, G, Yan, C, Shi, Y.
登録日2013-08-12
公開日2013-11-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.781 Å)
主引用文献Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA.
Nature, 506, 2014
6XZT
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BU of 6xzt by Molmil
Crystal structure of helicase Pif1 from Thermus oshimai mutant G110C-E410C
分子名称: PIF1 helicase
著者Dai, Y.X, Chen, W.F, Teng, F.Y, Liu, N.N, Hou, X.M, Dou, S.X, Rety, S, Xi, X.G.
登録日2020-02-05
公開日2021-02-17
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.341 Å)
主引用文献Structural and functional studies of SF1B Pif1 from Thermus oshimai reveal dimerization-induced helicase inhibition.
Nucleic Acids Res., 49, 2021
7ZFG
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BU of 7zfg by Molmil
VDR complex with aromatic D-ring analog
分子名称: (1R,3S,5Z)-4-methylidene-5-[(E)-9-methyl-3-[3-(6-methyl-6-oxidanyl-heptyl)phenyl]-9-oxidanyl-dec-2-enylidene]cyclohexane-1,3-diol, ACETATE ION, Nuclear receptor coactivator 1, ...
著者Rochel, N.
登録日2022-04-01
公開日2022-11-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Design, Synthesis, Biological Activity, and Structural Analysis of Novel Des-C-Ring and Aromatic-D-Ring Analogues of 1 alpha ,25-Dihydroxyvitamin D 3.
J.Med.Chem., 65, 2022
4JKC
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BU of 4jkc by Molmil
Open and closed forms of T1800E human PRP8 RNase H-like domain with bound Mg ion
分子名称: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ...
著者Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M.
登録日2013-03-09
公開日2013-05-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation.
Nat.Struct.Mol.Biol., 20, 2013
4JK7
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BU of 4jk7 by Molmil
Open and closed forms of wild-type human PRP8 RNase H-like domain with bound Mg ion
分子名称: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ...
著者Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K, MacMillan, A.M.
登録日2013-03-09
公開日2013-05-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation.
Nat.Struct.Mol.Biol., 20, 2013
4JKD
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BU of 4jkd by Molmil
Open and closed forms of I1790Y human PRP8 RNase H-like domain with bound Mg ion
分子名称: CHLORIDE ION, MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8
著者Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M.
登録日2013-03-09
公開日2013-05-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation.
Nat.Struct.Mol.Biol., 20, 2013
8E3S
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BU of 8e3s by Molmil
CryoEM structure of yeast Arginyltransferase 1 (ATE1)
分子名称: Arginyl-tRNA--protein transferase 1, ZINC ION
著者Huang, W, Zhang, Y, Taylor, D.J.
登録日2022-08-17
公開日2023-04-26
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献The structural basis of tRNA recognition by arginyl-tRNA-protein transferase.
Nat Commun, 14, 2023
3EE4
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BU of 3ee4 by Molmil
R2-like ligand binding Mn/Fe oxidase from M. tuberculosis
分子名称: FE (III) ION, MANGANESE (III) ION, MYRISTIC ACID, ...
著者Andersson, C.S, Jones, T.A, Hogbom, M.
登録日2008-09-04
公開日2009-04-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A Mycobacterium tuberculosis ligand-binding Mn/Fe protein reveals a new cofactor in a remodeled R2-protein scaffold
Proc.Natl.Acad.Sci.Usa, 106, 2009
1UST
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BU of 1ust by Molmil
YEAST HISTONE H1 GLOBULAR DOMAIN I, HHO1P GI, SOLUTION NMR STRUCTURES
分子名称: HISTONE H1
著者Ali, T, Coles, P, Stevens, T.J, Stott, K, Thomas, J.O.
登録日2003-11-30
公開日2004-04-01
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Two Homologous Domains of Similar Structure But Different Stability in the Yeast Linker Histone, Hho1P
J.Mol.Biol., 338, 2004
1USS
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BU of 1uss by Molmil
YEAST HISTONE H1 GLOBULAR DOMAIN II, HHO1P GII, SOLUTION NMR STRUCTURES
分子名称: HISTONE H1
著者Ali, T, Coles, P, Stevens, T.J, Stott, K, Thomas, J.O.
登録日2003-11-30
公開日2004-04-01
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Two Homologous Domains of Similar Structure But Different Stability in the Yeast Linker Histone, Hho1P
J.Mol.Biol., 338, 2004
6ZJK
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BU of 6zjk by Molmil
Ribonucleotide reductase R2 subunit from Clostridium botulinum
分子名称: FE (III) ION, GLYCEROL, Ribonucleoside-diphosphate reductase subunit beta
著者Martinez-Carranza, M, Stenmark, P.
登録日2020-06-29
公開日2020-09-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A ribonucleotide reductase from Clostridium botulinum reveals distinct evolutionary pathways to regulation via the overall activity site.
J.Biol.Chem., 295, 2020
7MMT
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BU of 7mmt by Molmil
Crystal Structure of the Class Ie Ribonucleotide Reductase Beta Subunit from Aerococcus urinae with Cu(I) bound (Cu chloride soak)
分子名称: CHLORIDE ION, COPPER (I) ION, GLYCEROL, ...
著者Palowitch, G.M, Boal, A.K.
登録日2021-04-30
公開日2022-05-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Ribonucleotide Reductase
To be published
7MMV
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BU of 7mmv by Molmil
Crystal Structure of the Class Ie Ribonucleotide Reductase Beta Subunit from Aerococcus urinae with Cu(I) bound (Cu sulfate soak)
分子名称: CHLORIDE ION, COPPER (I) ION, GLYCEROL, ...
著者Palowitch, G.M, Boal, A.K.
登録日2021-04-30
公開日2022-05-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Ribonucleotide Reductas
To be published
7MMP
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BU of 7mmp by Molmil
Crystal Structure of the Class Ie Ribonucleotide Reductase
分子名称: CALCIUM ION, FLAVIN MONONUCLEOTIDE, Protein NrdI, ...
著者Palowitch, G.M, Boal, A.K.
登録日2021-04-30
公開日2022-05-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Ribonucleotide Reductase
To be published
7MMS
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BU of 7mms by Molmil
Crystal Structure of the Class Ie Ribonucleotide Reductase Beta-NrdI complex from Aerococcus urinae in Semiquinone Form with Cu(I) bound
分子名称: 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, CALCIUM ION, COPPER (I) ION, ...
著者Palowitch, G.M, Boal, A.K.
登録日2021-04-30
公開日2022-05-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Ribonucleotide Reductase
To be published
7MMR
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BU of 7mmr by Molmil
Crystal Structure of the Class Ie Ribonucleotide Reductase Beta-NrdI complex from Aerococcus urinae in Oxidized Form with Cu(I) bound
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, COPPER (I) ION, ...
著者Palowitch, G.M, Boal, A.K.
登録日2021-04-30
公開日2022-05-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Ribonucleotide Reductase
To be published
7MMQ
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BU of 7mmq by Molmil
Crystal Structure of the Class Ie Ribonucleotide Reductase Beta-NrdI complex from Aerococcus urinae in Reduced Hydroquinone Form
分子名称: FLAVIN MONONUCLEOTIDE, GLYCEROL, Protein NrdI, ...
著者Palowitch, G.M, Boal, A.K.
登録日2021-04-30
公開日2022-05-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Ribonucleotide Reductase
To be published
7MMW
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BU of 7mmw by Molmil
Crystal Structure of the Class Ie Ribonucleotide Reductase Beta Subunit from Aerococcus urinae (in alternate conformation)
分子名称: CALCIUM ION, Ribonucleoside-diphosphate reductase
著者Palowitch, G.M, Boal, A.K.
登録日2021-04-30
公開日2022-05-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Ribonucleotide Reductase
To be published
7MMU
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BU of 7mmu by Molmil
Crystal Structure of the Class Ie Ribonucleotide Reductase Beta Subunit from Aerococcus urinae with Cu(I) bound (Cu acetonitrile soak)
分子名称: CHLORIDE ION, COPPER (I) ION, Ribonucleoside-diphosphate reductase
著者Palowitch, G.M, Boal, A.K.
登録日2021-04-30
公開日2022-05-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Ribonucleotide Reductase
To be published
7KJV
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BU of 7kjv by Molmil
Structure of HIV-1 reverse transcriptase initiation complex core
分子名称: HIV-1 viral RNA fragment, MAGNESIUM ION, Reverse transcriptase/ribonuclease H, ...
著者Ha, B, Larsen, K.P, Zhang, J, Fu, Z, Montabana, E, Jackson, L.N, Chen, D.H, Puglisi, E.V.
登録日2020-10-26
公開日2021-03-17
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献High-resolution view of HIV-1 reverse transcriptase initiation complexes and inhibition by NNRTI drugs.
Nat Commun, 12, 2021
4JK9
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BU of 4jk9 by Molmil
Open and closed forms of wild-type human PRP8 RNase H-like domain with bound Co ion
分子名称: CHLORIDE ION, COBALT (II) ION, GLYCEROL, ...
著者Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M.
登録日2013-03-09
公開日2013-05-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation.
Nat.Struct.Mol.Biol., 20, 2013
4JKH
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BU of 4jkh by Molmil
Open and closed forms of D1781E human PRP8 RNase H-like domain with bound Mg ion
分子名称: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ...
著者Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M.
登録日2013-03-09
公開日2013-05-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation.
Nat.Struct.Mol.Biol., 20, 2013

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件を2024-11-06に公開中

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