8FZQ
| Dehosphorylated, ATP-bound human cystic fibrosis transmembrane conductance regulator (CFTR) | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION | 著者 | Levring, J, Terry, D.S, Kilic, Z, Fitzgerald, G.A, Blanchard, S.C, Chen, J. | 登録日 | 2023-01-29 | 公開日 | 2023-03-29 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | CFTR function, pathology and pharmacology at single-molecule resolution. Nature, 616, 2023
|
|
8DYP
| |
7D87
| |
4M7A
| Crystal structure of Lsm2-8 complex bound to the 3' end sequence of U6 snRNA | 分子名称: | U6 snRNA, U6 snRNA-associated Sm-like protein LSm2, U6 snRNA-associated Sm-like protein LSm3, ... | 著者 | Zhou, L, Hang, J, Zhou, Y, Wan, R, Lu, G, Yan, C, Shi, Y. | 登録日 | 2013-08-12 | 公開日 | 2013-11-13 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.781 Å) | 主引用文献 | Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA. Nature, 506, 2014
|
|
6XZT
| Crystal structure of helicase Pif1 from Thermus oshimai mutant G110C-E410C | 分子名称: | PIF1 helicase | 著者 | Dai, Y.X, Chen, W.F, Teng, F.Y, Liu, N.N, Hou, X.M, Dou, S.X, Rety, S, Xi, X.G. | 登録日 | 2020-02-05 | 公開日 | 2021-02-17 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (3.341 Å) | 主引用文献 | Structural and functional studies of SF1B Pif1 from Thermus oshimai reveal dimerization-induced helicase inhibition. Nucleic Acids Res., 49, 2021
|
|
7ZFG
| VDR complex with aromatic D-ring analog | 分子名称: | (1R,3S,5Z)-4-methylidene-5-[(E)-9-methyl-3-[3-(6-methyl-6-oxidanyl-heptyl)phenyl]-9-oxidanyl-dec-2-enylidene]cyclohexane-1,3-diol, ACETATE ION, Nuclear receptor coactivator 1, ... | 著者 | Rochel, N. | 登録日 | 2022-04-01 | 公開日 | 2022-11-23 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | Design, Synthesis, Biological Activity, and Structural Analysis of Novel Des-C-Ring and Aromatic-D-Ring Analogues of 1 alpha ,25-Dihydroxyvitamin D 3. J.Med.Chem., 65, 2022
|
|
4JKC
| Open and closed forms of T1800E human PRP8 RNase H-like domain with bound Mg ion | 分子名称: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | 著者 | Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M. | 登録日 | 2013-03-09 | 公開日 | 2013-05-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation. Nat.Struct.Mol.Biol., 20, 2013
|
|
4JK7
| Open and closed forms of wild-type human PRP8 RNase H-like domain with bound Mg ion | 分子名称: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | 著者 | Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K, MacMillan, A.M. | 登録日 | 2013-03-09 | 公開日 | 2013-05-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation. Nat.Struct.Mol.Biol., 20, 2013
|
|
4JKD
| Open and closed forms of I1790Y human PRP8 RNase H-like domain with bound Mg ion | 分子名称: | CHLORIDE ION, MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8 | 著者 | Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M. | 登録日 | 2013-03-09 | 公開日 | 2013-05-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation. Nat.Struct.Mol.Biol., 20, 2013
|
|
8E3S
| |
3EE4
| R2-like ligand binding Mn/Fe oxidase from M. tuberculosis | 分子名称: | FE (III) ION, MANGANESE (III) ION, MYRISTIC ACID, ... | 著者 | Andersson, C.S, Jones, T.A, Hogbom, M. | 登録日 | 2008-09-04 | 公開日 | 2009-04-07 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A Mycobacterium tuberculosis ligand-binding Mn/Fe protein reveals a new cofactor in a remodeled R2-protein scaffold Proc.Natl.Acad.Sci.Usa, 106, 2009
|
|
1UST
| YEAST HISTONE H1 GLOBULAR DOMAIN I, HHO1P GI, SOLUTION NMR STRUCTURES | 分子名称: | HISTONE H1 | 著者 | Ali, T, Coles, P, Stevens, T.J, Stott, K, Thomas, J.O. | 登録日 | 2003-11-30 | 公開日 | 2004-04-01 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Two Homologous Domains of Similar Structure But Different Stability in the Yeast Linker Histone, Hho1P J.Mol.Biol., 338, 2004
|
|
1USS
| YEAST HISTONE H1 GLOBULAR DOMAIN II, HHO1P GII, SOLUTION NMR STRUCTURES | 分子名称: | HISTONE H1 | 著者 | Ali, T, Coles, P, Stevens, T.J, Stott, K, Thomas, J.O. | 登録日 | 2003-11-30 | 公開日 | 2004-04-01 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Two Homologous Domains of Similar Structure But Different Stability in the Yeast Linker Histone, Hho1P J.Mol.Biol., 338, 2004
|
|
6ZJK
| |
7MMT
| |
7MMV
| |
7MMP
| |
7MMS
| |
7MMR
| |
7MMQ
| |
7MMW
| |
7MMU
| |
7KJV
| Structure of HIV-1 reverse transcriptase initiation complex core | 分子名称: | HIV-1 viral RNA fragment, MAGNESIUM ION, Reverse transcriptase/ribonuclease H, ... | 著者 | Ha, B, Larsen, K.P, Zhang, J, Fu, Z, Montabana, E, Jackson, L.N, Chen, D.H, Puglisi, E.V. | 登録日 | 2020-10-26 | 公開日 | 2021-03-17 | 最終更新日 | 2024-10-23 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | High-resolution view of HIV-1 reverse transcriptase initiation complexes and inhibition by NNRTI drugs. Nat Commun, 12, 2021
|
|
4JK9
| Open and closed forms of wild-type human PRP8 RNase H-like domain with bound Co ion | 分子名称: | CHLORIDE ION, COBALT (II) ION, GLYCEROL, ... | 著者 | Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M. | 登録日 | 2013-03-09 | 公開日 | 2013-05-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation. Nat.Struct.Mol.Biol., 20, 2013
|
|
4JKH
| Open and closed forms of D1781E human PRP8 RNase H-like domain with bound Mg ion | 分子名称: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | 著者 | Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M. | 登録日 | 2013-03-09 | 公開日 | 2013-05-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation. Nat.Struct.Mol.Biol., 20, 2013
|
|