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7BWD
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BU of 7bwd by Molmil
Structure of Dot1L-H2BK34ub Nucleosome Complex
分子名称: DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ...
著者Lou, Z.Y, Liu, L, Cao, L, Ai, H.S, Sun, Z.X.
登録日2020-04-14
公開日2021-04-14
実験手法ELECTRON MICROSCOPY (4.32 Å)
主引用文献Structure of the Dot1L-H2BK34ub Nucleosome Complex Reveals an Unprecedented Crosstalk Activation Mechanism through Nucleosome Shape Distortion
To Be Published
6WJD
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BU of 6wjd by Molmil
SA-like state of human 26S Proteasome with non-cleavable M1-linked hexaubiquitin and E3 ubiquitin ligase E6AP/UBE3A
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
著者Chen, X, Walters, K.J.
登録日2020-04-13
公開日2020-08-05
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Cryo-EM Reveals Unanchored M1-Ubiquitin Chain Binding at hRpn11 of the 26S Proteasome.
Structure, 28, 2020
7BU0
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BU of 7bu0 by Molmil
Crystal structure of a OTU deubiquitinase in complex with Ub-PA
分子名称: Polyubiquitin-B, Uncharacterized protein, prop-2-en-1-amine
著者Ouyang, S.Y, Zhen, X.K.
登録日2020-04-03
公開日2020-11-18
最終更新日2023-04-05
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Interplay between bacterial deubiquitinase and ubiquitin E3 ligase regulates ubiquitin dynamics on Legionella phagosomes.
Elife, 9, 2020
6W9S
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BU of 6w9s by Molmil
Crystal structure of an OTU deubiquitinase from Escherichia albertii bound to ubiquitin
分子名称: FORMIC ACID, OTU domain-containing protein EschOTU, Ubiquitin
著者Schubert, A.F, Pruneda, J.N, Komander, D.
登録日2020-03-23
公開日2020-07-01
最終更新日2020-08-12
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Identification and characterization of diverse OTU deubiquitinases in bacteria.
Embo J., 39, 2020
6W9R
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BU of 6w9r by Molmil
Crystal structure of an OTU deubiquitinase from Wolbachia pipientis wMel bound to ubiquitin
分子名称: CITRATE ANION, OTU domain-containing protein wMelOTU, Ubiquitin
著者Schubert, A.F, Pruneda, J.N, Komander, D.
登録日2020-03-23
公開日2020-07-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Identification and characterization of diverse OTU deubiquitinases in bacteria.
Embo J., 39, 2020
6W9D
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BU of 6w9d by Molmil
RNF12 RING domain in complex with a Ube2d2~Ub conjugate
分子名称: E3 ubiquitin-protein ligase RLIM, IODIDE ION, Ubiquitin, ...
著者Middleton, A.J, Day, C.L.
登録日2020-03-22
公開日2020-05-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献The RING Domain of RING Finger 12 Efficiently Builds Degradative Ubiquitin Chains.
J.Mol.Biol., 432, 2020
6YBS
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BU of 6ybs by Molmil
Structure of a human 48S translational initiation complex - head
分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S12, ...
著者Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V.
登録日2020-03-17
公開日2020-09-16
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structure of a human 48Stranslational initiation complex.
Science, 369, 2020
6YAN
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BU of 6yan by Molmil
Mammalian 48S late-stage translation initiation complex with histone 4 mRNA
分子名称: 18S ribosomal RNA, 40S ribosomal protein S12, 40S ribosomal protein S21, ...
著者Bochler, A, Simonetti, A, Guca, E, Hashem, Y.
登録日2020-03-12
公開日2020-04-08
最終更新日2020-04-22
実験手法ELECTRON MICROSCOPY (3.48 Å)
主引用文献Structural Insights into the Mammalian Late-Stage Initiation Complexes.
Cell Rep, 31, 2020
6YAM
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BU of 6yam by Molmil
Mammalian 48S late-stage translation initiation complex (LS48S+eIF3 IC) with beta-globin mRNA
分子名称: 18S ribosomal RNA, 40S ribosomal protein eS1, 40S ribosomal protein eS10, ...
著者Bochler, A, Simonetti, A, Guca, E, Hashem, Y.
登録日2020-03-12
公開日2020-04-08
最終更新日2020-04-22
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural Insights into the Mammalian Late-Stage Initiation Complexes.
Cell Rep, 31, 2020
6YAL
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BU of 6yal by Molmil
Mammalian 48S late-stage initiation complex with beta-globin mRNA
分子名称: 18S ribosomal RNA, 40S Ribosomal protein uS3, 40S Ribosomal protein uS7, ...
著者Bochler, A, Simonetti, A, Guca, E, Hashem, Y.
登録日2020-03-12
公開日2020-04-08
最終更新日2020-04-22
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural Insights into the Mammalian Late-Stage Initiation Complexes.
Cell Rep, 31, 2020
6W2T
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BU of 6w2t by Molmil
Structure of the Cricket Paralysis Virus 5-UTR IRES (CrPV 5-UTR-IRES) bound to the small ribosomal subunit in the closed state (Class 2)
分子名称: 18S rRNA, CrPV 5'-UTR IRES, Eukaryotic translation initiation factor 3 subunit A, ...
著者Neupane, R, Pisareva, V, Rodriguez, C.F, Pisarev, A, Fernandez, I.S.
登録日2020-03-08
公開日2020-04-22
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献A complex IRES at the 5'-UTR of a viral mRNA assembles a functional 48S complex via an uAUG intermediate.
Elife, 9, 2020
6W2S
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BU of 6w2s by Molmil
Structure of the Cricket Paralysis Virus 5-UTR IRES (CrPV 5-UTR-IRES) bound to the small ribosomal subunit in the open state (Class 1)
分子名称: 18S rRNA, CrPV 5'-UTR IRES, Eukaryotic translation initiation factor 3 subunit A, ...
著者Neupane, R, Pisareva, V, Rodriguez, C.F, Pisarev, A, Fernandez, I.S.
登録日2020-03-08
公開日2020-04-22
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献A complex IRES at the 5'-UTR of a viral mRNA assembles a functional 48S complex via an uAUG intermediate.
Elife, 9, 2020
6Y5Q
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BU of 6y5q by Molmil
human 17S U2 snRNP
分子名称: HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, Probable ATP-dependent RNA helicase DDX46, ...
著者Zhang, Z, Will, C.L, Bertram, K, Luehrmann, R, Stark, H.
登録日2020-02-25
公開日2020-06-17
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (7.1 Å)
主引用文献Molecular architecture of the human 17S U2 snRNP.
Nature, 583, 2020
6Y57
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BU of 6y57 by Molmil
Structure of human ribosome in hybrid-PRE state
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A.
登録日2020-02-25
公開日2020-04-15
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes.
Cell Rep, 31, 2020
6Y53
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BU of 6y53 by Molmil
human 17S U2 snRNP low resolution part
分子名称: HIV Tat-specific factor 1, Probable ATP-dependent RNA helicase DDX46, Small nuclear ribonucleoprotein E, ...
著者Zhang, Z, Will, C.L, Bertram, K, Luehrmann, R, Stark, H.
登録日2020-02-24
公開日2020-06-17
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (7.1 Å)
主引用文献Molecular architecture of the human 17S U2 snRNP.
Nature, 583, 2020
6VW2
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BU of 6vw2 by Molmil
Cryo-EM structure of human islet amyloid polypeptide (hIAPP, or amylin) fibrils
分子名称: Islet amyloid polypeptide (SUMO-tagged)
著者Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S.
登録日2020-02-18
公開日2020-06-10
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structure and inhibitor design of human IAPP (amylin) fibrils.
Nat.Struct.Mol.Biol., 27, 2020
6Y2L
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BU of 6y2l by Molmil
Structure of human ribosome in POST state
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ...
著者Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A.
登録日2020-02-16
公開日2020-04-15
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes.
Cell Rep, 31, 2020
6Y0G
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BU of 6y0g by Molmil
Structure of human ribosome in classical-PRE state
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ...
著者Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A.
登録日2020-02-07
公開日2020-04-15
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes.
Cell Rep, 31, 2020
6XZ1
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BU of 6xz1 by Molmil
Conjugate of the HECT domain of HUWE1 with ubiquitin
分子名称: HECT, UBA and WWE domain containing 1, isoform CRA_a, ...
著者Liu, B, Seenivasan, A, Nair, R, Chen, D, Lowe, E.D, Lorenz, S.
登録日2020-01-31
公開日2021-08-25
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Reconstitution and Structural Analysis of a HECT Ligase-Ubiquitin Complex via an Activity-Based Probe.
Acs Chem.Biol., 16, 2021
6TXB
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BU of 6txb by Molmil
Crystal structure of Mindy1 mutant (P138A) in complex with Lys48 linked di-ubiquitin
分子名称: CHLORIDE ION, Polyubiquitin-C, SODIUM ION, ...
著者Abdul Rehman, S.A, Kulathu, Y.
登録日2020-01-14
公開日2021-01-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2.
Mol.Cell, 81, 2021
6LQM
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BU of 6lqm by Molmil
Cryo-EM structure of a pre-60S ribosomal subunit - state C
分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N.
登録日2020-01-14
公開日2020-08-26
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献Structural snapshots of human pre-60S ribosomal particles before and after nuclear export.
Nat Commun, 11, 2020
6TUV
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BU of 6tuv by Molmil
Crystal structure of Mindy1 in complex with Lys48 linked di-ubiquitin
分子名称: Polyubiquitin-C, SULFATE ION, Ubiquitin carboxyl-terminal hydrolase MINDY-1
著者Abdul Rehman, S.A, Kulathu, Y.
登録日2020-01-08
公開日2021-01-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2.
Mol.Cell, 81, 2021
6LP2
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BU of 6lp2 by Molmil
Structure of Lpg2148/UBE2N-Ub complex
分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 N, Uncharacterized protein lpg2148
著者Feng, Y, Wang, Y, Huang, Y, Li, D.
登録日2020-01-08
公開日2021-01-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.479 Å)
主引用文献Structure of Lpg2148/UBE2N-Ub complex
To Be Published
6VEL
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BU of 6vel by Molmil
Crystal Structure of Human E-cadherin bound by mouse monoclonal antibody 66E8Fab
分子名称: 66E8 Fab Heavy Chain, 66E8 Fab Light Chain, CALCIUM ION, ...
著者Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2020-01-02
公開日2020-01-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Regulation of multiple dimeric states of E-cadherin by adhesion activating antibodies revealed through Cryo-EM and X-ray crystallography.
Pnas Nexus, 1, 2022
6VEN
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BU of 6ven by Molmil
Yeast COMPASS in complex with a ubiquitinated nucleosome
分子名称: 601 DNA (146-MER), COMPASS component BRE2, COMPASS component SDC1, ...
著者Worden, E.J, Wolberger, C.
登録日2020-01-02
公開日2020-01-15
最終更新日2020-01-22
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Structural basis for COMPASS recognition of an H2B-ubiquitinated nucleosome.
Elife, 9, 2020

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