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1MA7
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Crystal structure of Cre site-specific recombinase complexed with a mutant DNA substrate, LoxP-A8/T27
分子名称: CRE RECOMBINASE, LOXP
著者Martin, S.S, Chu, V.C, Baldwin, E.P.
登録日2002-08-01
公開日2003-07-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Modulation of the active complex assembly and turnover rate by protein-DNA interactions in Cre-LoxP recombination
Biochemistry, 42, 2003
8H3Q
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BU of 8h3q by Molmil
Cryo-EM Structure of the CAND1-Cul3-Rbx1 complex
分子名称: Cullin-3, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ...
著者Hu, Y, Mao, Q, Chen, Z, Sun, L.
登録日2022-10-09
公開日2023-10-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.76 Å)
主引用文献Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2.
Nat.Struct.Mol.Biol., 31, 2024
8GQ6
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Cryo-EM Structure of the KBTBD2-CUL3-Rbx1 dimeric complex
分子名称: Cullin-3, E3 ubiquitin-protein ligase RBX1, Kelch repeat and BTB domain-containing protein 2, ...
著者Sun, L, Chen, Z, Hu, Y, Mao, Q.
登録日2022-08-29
公開日2023-09-06
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.96 Å)
主引用文献Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2.
Nat.Struct.Mol.Biol., 31, 2024
8K9I
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Structure of CUL3-RBX1-KLHL22 complex without CUL3 NA motif
分子名称: Cullin-3, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ...
著者Wang, W, Ling, L, Dai, Z, Zuo, P, Yin, Y.
登録日2023-08-01
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献A conserved N-terminal motif of CUL3 contributes to assembly and E3 ligase activity of CRL3 KLHL22.
Nat Commun, 15, 2024
8H33
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Cryo-EM Structure of the KBTBD2-Cul3-Rbx1 tetrameric complex
分子名称: Cullin-3, E3 ubiquitin-protein ligase RBX1, Kelch repeat and BTB domain-containing protein 2, ...
著者Hu, Y, Mao, Q, Chen, Z, Sun, L.
登録日2022-10-07
公開日2023-10-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (7.86 Å)
主引用文献Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2.
Nat.Struct.Mol.Biol., 31, 2024
8H35
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Cryo-EM Structure of the KBTBD2-Cul3-Rbx1 octameric complex
分子名称: Cullin-3, E3 ubiquitin-protein ligase RBX1, Kelch repeat and BTB domain-containing protein 2, ...
著者Hu, Y, Mao, Q, Chen, Z, Sun, L.
登録日2022-10-08
公開日2023-10-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (7.41 Å)
主引用文献Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2.
Nat.Struct.Mol.Biol., 31, 2024
8H34
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Cryo-EM Structure of the KBTBD2-Cul3-Rbx1 hexameric complex
分子名称: Cullin-3, E3 ubiquitin-protein ligase RBX1, Kelch repeat and BTB domain-containing protein 2, ...
著者Hu, Y, Mao, Q, Chen, Z, Sun, L.
登録日2022-10-07
公開日2023-10-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (7.99 Å)
主引用文献Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2.
Nat.Struct.Mol.Biol., 31, 2024
8H3R
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Cryo-EM Structure of the KBTBD2-CRL3~N8 dimeric complex
分子名称: Cullin-3, E3 ubiquitin-protein ligase RBX1, Kelch repeat and BTB domain-containing protein 2, ...
著者Hu, Y, Mao, Q, Chen, Z, Sun, L.
登録日2022-10-09
公開日2023-10-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (6.36 Å)
主引用文献Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2.
Nat.Struct.Mol.Biol., 31, 2024
4F52
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Structure of a Glomulin-RBX1-CUL1 complex
分子名称: Cullin-1, E3 ubiquitin-protein ligase RBX1, Glomulin, ...
著者Duda, D.M, Olszewski, J.L, Schulman, B.A.
登録日2012-05-11
公開日2012-09-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of a Glomulin-RBX1-CUL1 Complex: Inhibition of a RING E3 Ligase through Masking of Its E2-Binding Surface.
Mol.Cell, 47, 2012
6NDL
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BU of 6ndl by Molmil
Crystal structure of Staphylococcus aureus biotin protein ligase in complex with a sulfonamide inhibitor
分子名称: 1-[4-(6-aminopurin-9-yl)butylsulfamoyl]-3-[4-[(4~{S})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]butyl]urea, Biotin Protein Ligase, GLYCEROL
著者Marshall, A.C, Polyak, S.W, Bruning, J.B, Lee, K.
登録日2018-12-13
公開日2019-12-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Sulfonamide-Based Inhibitors of Biotin Protein Ligase as New Antibiotic Leads.
Acs Chem.Biol., 14, 2019
7V8F
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Crystal structure of UBE2L3 bound to HOIP RING1 domain.
分子名称: E3 ubiquitin-protein ligase RNF31, Ubiquitin-conjugating enzyme E2 L3, ZINC ION
著者Liu, J, Wang, Y, Pan, L.
登録日2021-08-22
公開日2022-03-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri.
Proc.Natl.Acad.Sci.USA, 119, 2022
7Z8R
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BU of 7z8r by Molmil
CAND1-CUL1-RBX1
分子名称: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ...
著者Baek, K, Schulman, B.A.
登録日2022-03-18
公開日2023-04-19
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.
Cell, 186, 2023
8E40
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Full-length APOBEC3G in complex with HIV-1 Vif, CBF-beta, and fork RNA
分子名称: Core-binding factor subunit beta, DNA dC->dU-editing enzyme APOBEC-3G, RNA, ...
著者Ito, F, Alvarez-Cabrera, A.L, Liu, S, Yang, H, Shiriaeva, A, Zhou, Z.H, Chen, X.S.
登録日2022-08-17
公開日2023-01-11
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.57 Å)
主引用文献Structural basis for HIV-1 antagonism of host APOBEC3G via Cullin E3 ligase.
Sci Adv, 9, 2023
1E8C
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BU of 1e8c by Molmil
Structure of MurE the UDP-N-acetylmuramyl tripeptide synthetase from E. coli
分子名称: 2,6-DIAMINOPIMELIC ACID, CHLORIDE ION, UDP-N-ACETYLMURAMOYLALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE, ...
著者Gordon, E.J, Chantala, L, Dideberg, O.
登録日2000-09-19
公開日2001-09-13
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of Udp-N-Acetylmuramoyl-L-Alanyl-D-Glutamate: Meso-Diaminopimelate Ligase from Escherichia Coli
J.Biol.Chem., 276, 2001
3CRX
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BU of 3crx by Molmil
CRE RECOMBINASE/DNA COMPLEX INTERMEDIATE I
分子名称: CRE RECOMBINASE, DNA 35-MER
著者Gopaul, D.N, Guo, F, Vanduyne, G.D.
登録日1998-06-19
公開日1999-12-14
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the Holliday junction intermediate in Cre-loxP site-specific recombination.
EMBO J., 17, 1998
5IAY
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BU of 5iay by Molmil
NMR structure of UHRF1 Tandem Tudor Domains in a complex with Spacer peptide
分子名称: E3 ubiquitin-protein ligase UHRF1, Spacer
著者Fang, J, Cheng, J, Wang, J, Zhang, Q, Liu, M, Gong, R, Wang, P, Zhang, X, Feng, Y, Lan, W, Gong, Z, Tang, C, Wong, J, Yang, H, Cao, C, Xu, Y.
登録日2016-02-22
公開日2016-04-20
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Hemi-methylated DNA opens a closed conformation of UHRF1 to facilitate its histone recognition
Nat Commun, 7, 2016
6FE8
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BU of 6fe8 by Molmil
Cryo-EM structure of the core Centromere Binding Factor 3 complex
分子名称: Centromere DNA-binding protein complex CBF3 subunit B, Centromere DNA-binding protein complex CBF3 subunit C, Suppressor of kinetochore protein 1
著者Zhang, W.J, Lukoynova, N, Miah, S, Vaughan, C.K.
登録日2017-12-30
公開日2018-08-01
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Insights into Centromere DNA Bending Revealed by the Cryo-EM Structure of the Core Centromere Binding Factor 3 with Ndc10.
Cell Rep, 24, 2018
7XZZ
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BU of 7xzz by Molmil
Cryo-EM structure of the nucleosome in complex with p53
分子名称: Cellular tumor antigen p53, DNA (169-MER), Histone H2A type 1-B/E, ...
著者Nishimura, M, Nozawa, K, Takizawa, Y, Kurumizaka, H.
登録日2022-06-03
公開日2022-10-12
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (4.07 Å)
主引用文献Structural basis for p53 binding to its nucleosomal target DNA sequence.
Pnas Nexus, 1, 2022
2LGV
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BU of 2lgv by Molmil
Rbx1
分子名称: E3 ubiquitin-protein ligase RBX1, ZINC ION
著者Spratt, D.E, Shaw, G.S.
登録日2011-08-02
公開日2012-03-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Selective recruitment of an e2~ubiquitin complex by an e3 ubiquitin ligase.
J.Biol.Chem., 287, 2012
8AG4
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BU of 8ag4 by Molmil
Vaccinia C16 protein bound to Ku70/Ku80
分子名称: Protein C10, X-ray repair cross-complementing protein 5, X-ray repair cross-complementing protein 6
著者Rivera-Calzada, A, Arribas-Bosacoma, R, Pearl, L.H, Llorca, O.
登録日2022-07-19
公開日2022-11-09
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.46 Å)
主引用文献Structural basis for the inactivation of cytosolic DNA sensing by the vaccinia virus.
Nat Commun, 13, 2022
8AG5
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Vaccinia C16 protein bound to Ku70/Ku80
分子名称: Ku70-Xrcc6, Protein C10, X-ray repair cross-complementing protein 5
著者Rivera-Calzada, A, Arribas-Bosacoma, R, Pearl, L.H, Llorca, O.
登録日2022-07-19
公開日2022-11-09
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Structural basis for the inactivation of cytosolic DNA sensing by the vaccinia virus.
Nat Commun, 13, 2022
2B5N
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BU of 2b5n by Molmil
Crystal Structure of the DDB1 BPB Domain
分子名称: ISOPROPYL ALCOHOL, damage-specific DNA binding protein 1
著者Li, T, Chen, X, Garbutt, K.C, Zhou, P, Zheng, N.
登録日2005-09-28
公開日2006-02-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of DDB1 in complex with a paramyxovirus V protein: viral hijack of a propeller cluster in ubiquitin ligase.
Cell(Cambridge,Mass.), 124, 2006
8RAS
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Plastid-encoded RNA polymerase transcription elongation complex
分子名称: DNA (81-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Webster, M.W, Pramanick, I, Vergara-Cruces, A.
登録日2023-12-01
公開日2024-03-06
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (2.62 Å)
主引用文献Structure of the plant plastid-encoded RNA polymerase.
Cell, 187, 2024
8RDJ
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Plastid-encoded RNA polymerase transcription elongation complex (Integrated model)
分子名称: DNA (81-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Webster, M.W, Pramanick, I, Vergara-Cruces, A.
登録日2023-12-08
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (2.62 Å)
主引用文献Structure of the plant plastid-encoded RNA polymerase.
Cell, 187, 2024
8OL1
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cGAS-Nucleosome in complex with SPSB3-ELOBC (composite structure)
分子名称: Cyclic GMP-AMP synthase, DNA (145-MER), Elongin-B, ...
著者Xu, P.B, Ablasser, A.
登録日2023-03-29
公開日2024-02-14
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献The CRL5-SPSB3 ubiquitin ligase targets nuclear cGAS for degradation.
Nature, 627, 2024

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