8E40

Full-length APOBEC3G in complex with HIV-1 Vif, CBF-beta, and fork RNA

Summary for 8E40

• Entry DOI: 10.2210/pdb8e40/pdb
• EMDB information: 27875 27885 27887
• Descriptor: DNA dC->dU-editing enzyme APOBEC-3G, Virion infectivity factor, Core-binding factor subunit beta, ... (6 entities in total)
• Functional Keywords: viral protein - human protein complex, ribonucleoprotein complex, viral protein-rna complex, viral protein/rna
• Biological source: Macaca mulatta (Rhesus monkey); More
• Total number of polymer chains: 5
• Total formula weight: 99974.35

Authors

Ito, F.,Alvarez-Cabrera, A.L.,Liu, S.,Yang, H.,Shiriaeva, A.,Zhou, Z.H.,Chen, X.S. (deposition date: 2022-08-17, release date: 2023-01-11)

• Primary citation: Ito, F.,Alvarez-Cabrera, A.L.,Liu, S.,Yang, H.,Shiriaeva, A.,Zhou, Z.H.,Chen, X.S.; Structural basis for HIV-1 antagonism of host APOBEC3G via Cullin E3 ligase.; Sci Adv, 9:eade3168-eade3168, 2023; PubMed: 36598981; DOI: 10.1126/sciadv.ade3168

Experimental method

ELECTRON MICROSCOPY (3.57 Å)