8E40
Full-length APOBEC3G in complex with HIV-1 Vif, CBF-beta, and fork RNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | DNA dC->dU-editing enzyme APOBEC-3G | polymer | 386 | 45187.4 | 1 | UniProt (Q7YR23) Pfam (PF18750) Pfam (PF18782) In PDB | Macaca mulatta (Rhesus monkey) | Deoxycytidine deaminase |
| 2 | B | Virion infectivity factor | polymer | 178 | 21136.4 | 1 | UniProt (B2CPZ0) Pfam (PF00559) UniProt (by SIFTS) (P12504) In PDB | Human immunodeficiency virus 1 | Vif,SOR protein |
| 3 | C | Core-binding factor subunit beta | polymer | 157 | 18643.8 | 1 | UniProt (Q13951) Pfam (PF02312) In PDB | Homo sapiens (human) | CBF-beta,Polyomavirus enhancer-binding protein 2 beta subunit,PEA2-beta,PEBP2-beta,SL3-3 enhancer factor 1 subunit beta,SL3/AKV core-binding factor beta subunit |
| 4 | R | RNA | polymer | 22 | 6875.0 | 1 | Escherichia coli | ||
| 5 | r | RNA | polymer | 25 | 8000.9 | 1 | Escherichia coli | ||
| 6 | A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence modifications
A: 8 - 377 (UniProt: Q7YR23)
B: 1 - 177 (UniProt: B2CPZ0)
| PDB | External Database | Details |
|---|---|---|
| Gly -6 | - | expression tag |
| Pro -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Met 1 | - | expression tag |
| Lys 2 | - | expression tag |
| Pro 3 | - | expression tag |
| Gln 4 | - | expression tag |
| Ile 5 | - | expression tag |
| Arg 6 | - | expression tag |
| Asn 7 | - | expression tag |
| Asp 31 | Asn 24 | conflict |
| Pro 60 | Ser 53 | conflict |
| Asp 128 | Lys 121 | conflict |
| - | Cys 132 | deletion |
| - | Gln 133 | deletion |
| - | Lys 134 | deletion |
| - | Arg 135 | deletion |
| Ala 139 | Gly 136 | conflict |
| Glu 140 | Gly 137 | conflict |
| Ala 141 | Pro 138 | conflict |
| Gly 142 | His 139 | conflict |
| Trp 175 | Arg 168 | conflict |
| Gln 259 | Glu 252 | conflict |
| Thr 326 | Ala 319 | conflict |
| Leu 378 | - | expression tag |
| Gln 379 | - | expression tag |
| Asn 380 | - | expression tag |
| Gln 381 | - | expression tag |
| Gly 382 | - | expression tag |
| Asn 383 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 99843.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 99974.4 |
