PDB: 245011 件ウェブページステータス検索Chemie searchBIRD

---

5E2M	Crystal structure of human carbonic anhydrase isozyme I with 3-(cyclooctylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide 分子名称: 3-(cyclooctylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide, ACETATE ION, Carbonic anhydrase 1, ... 著者 Manakova, E, Smirnov, A, Grazulis, S. 登録日 2015-10-01 公開日 2016-10-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 Intrinsic Thermodynamics and Structures of 2,4- and 3,4-Substituted Fluorinated Benzenesulfonamides Binding to Carbonic Anhydrases. ChemMedChem, 12, 2017
9CEC	SARS-CoV-2 3CL Protease complexed with covalent inhibitor BC671 分子名称: 3C-like proteinase nsp5, DIMETHYL SULFOXIDE, N-[(2S)-1-{[(2S)-1-hydroxy-3-(2-oxo-1,2-dihydropyridin-3-yl)propan-2-yl]amino}-4-methyl-1-oxopentan-2-yl]-1H-indole-2-carboxamide 著者 Farzandh, S, Hoffpauir, Z.A, Meneely, K.M, Lamb, A.L. 登録日 2024-06-26 公開日 2025-01-15 最終更新日 2025-01-22 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Dual Inhibitors of SARS-CoV-2 3CL Protease and Human Cathepsin L Containing Glutamine Isosteres Are Anti-CoV-2 Agents. J.Am.Chem.Soc., 147, 2025
6TAH	Crystal structure of a Nu-class Glutathione-S-Transferase from Pseudomonas aeruginosa PACS2 bound to glutathione 分子名称: 1,2-ETHANEDIOL, GLYCEROL, Glutathione S-transferase, ... 著者 Feiler, C.G, Blankenfeldt, W. 登録日 2019-10-29 公開日 2020-09-16 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structure of nu-class glutathione transferase from Pseudomonas aeruginosa related to YfcG from E. coli To Be Published
5WLR	Carbonic Anhydrase IX-mimic in complex with aryloxy-2-hydroxypropylammine sulfonamide 分子名称: 4-{(2S)-2-hydroxy-3-[(propan-2-yl)amino]propoxy}benzene-1-sulfonamide, Carbonic Anhydrase IX-mimic, GLYCEROL, ... 著者 Lomelino, C.L, Andring, J.T, McKenna, R. 登録日 2017-07-27 公開日 2018-08-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Hybrids for multitargeted therapy Beta Adrenergic Receptor modulators CAIs To Be Published
7G9W	PanDDA analysis group deposition -- Crystal Structure of Zika virus NS3 Helicase in complex with Z444860982 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, N-[(3,5-dimethyl-1H-pyrazol-4-yl)methyl]cyclohexanamine, ... 著者 Godoy, A.S, Noske, G.D, Fairhead, M, Lithgo, R.M, Koekemoer, L, Aschenbrenner, J.C, Balcomb, B.H, Marples, P.G, Ni, X, Tomlinson, C.W.E, Wild, C, Mesquita, N.C.M.R, Oliva, G, Fearon, D, Walsh, M.A, von Delft, F. 登録日 2023-07-03 公開日 2023-07-26 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.855 Å) 主引用文献 PanDDA analysis group deposition To Be Published
7G9Z	PanDDA analysis group deposition -- Crystal Structure of Zika virus NS3 Helicase in complex with Z1216822028 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 2-(propan-2-yl)-1H-pyrrolo[3,2-b]pyridine, ... 著者 Godoy, A.S, Noske, G.D, Fairhead, M, Lithgo, R.M, Koekemoer, L, Aschenbrenner, J.C, Balcomb, B.H, Marples, P.G, Ni, X, Tomlinson, C.W.E, Wild, C, Mesquita, N.C.M.R, Oliva, G, Fearon, D, Walsh, M.A, von Delft, F. 登録日 2023-07-03 公開日 2023-07-26 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.622 Å) 主引用文献 PanDDA analysis group deposition To Be Published
7GA4	PanDDA analysis group deposition -- Crystal Structure of Zika virus NS3 Helicase in complex with Z56823075 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, PHOSPHATE ION, ... 著者 Godoy, A.S, Noske, G.D, Fairhead, M, Lithgo, R.M, Koekemoer, L, Aschenbrenner, J.C, Balcomb, B.H, Marples, P.G, Ni, X, Tomlinson, C.W.E, Wild, C, Mesquita, N.C.M.R, Oliva, G, Fearon, D, Walsh, M.A, von Delft, F. 登録日 2023-07-03 公開日 2023-07-26 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.749 Å) 主引用文献 PanDDA analysis group deposition To Be Published
5T3N	Sp-2Cl-cAMPS bound to PKAR CBD2 分子名称: (2S,4aR,6R,7R,7aS)-6-(6-amino-2-chloro-9H-purin-9-yl)-7-hydroxy-2-sulfanyltetrahydro-2H,4H-2lambda~5~-furo[3,2-d][1,3,2]dioxaphosphinin-2-one, IODIDE ION, cAMP-dependent protein kinase regulatory subunit 著者 Littler, D.R, Gilson, P. 登録日 2016-08-26 公開日 2016-10-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Disrupting the Allosteric Interaction between the Plasmodium falciparum cAMP-dependent Kinase and Its Regulatory Subunit. J. Biol. Chem., 291, 2016
7G9Q	PanDDA analysis group deposition -- Crystal Structure of Zika virus NS3 Helicase in complex with Z751811134 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, N,N-dimethylpyridine-3-sulfonamide, ... 著者 Godoy, A.S, Noske, G.D, Fairhead, M, Lithgo, R.M, Koekemoer, L, Aschenbrenner, J.C, Balcomb, B.H, Marples, P.G, Ni, X, Tomlinson, C.W.E, Wild, C, Mesquita, N.C.M.R, Oliva, G, Fearon, D, Walsh, M.A, von Delft, F. 登録日 2023-07-03 公開日 2023-07-26 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.131 Å) 主引用文献 PanDDA analysis group deposition To Be Published
9E9C	Mouse mitoribosome large subunit assembly intermediate bound to NSUN4, METRF4, GTPBP7, GTPBP10 and the MALSU1-L0R8F8-mt-ACP complex (without uL16m), State B1 (SAMC knock-out) 分子名称: 5-cytosine rRNA methyltransferase NSUN4, Acyl carrier protein, mitochondrial, ... 著者 Singh, V, Rorbach, J, Freyer, C, Amunts, A, Wredenberg, A. 登録日 2024-11-08 公開日 2025-08-06 実験手法 ELECTRON MICROSCOPY (3.62 Å) 主引用文献 The mitochondrial methylation potential gates mitoribosome assembly. Nat Commun, 16, 2025
7G9V	PanDDA analysis group deposition -- Crystal Structure of Zika virus NS3 Helicase in complex with Z383202616 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, N-(1H-indazol-6-yl)acetamide, ... 著者 Godoy, A.S, Noske, G.D, Fairhead, M, Lithgo, R.M, Koekemoer, L, Aschenbrenner, J.C, Balcomb, B.H, Marples, P.G, Ni, X, Tomlinson, C.W.E, Wild, C, Mesquita, N.C.M.R, Oliva, G, Fearon, D, Walsh, M.A, von Delft, F. 登録日 2023-07-03 公開日 2023-07-26 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 PanDDA analysis group deposition To Be Published
3FDS	Structural insight into recruitment of translesion DNA polymerase Dpo4 to sliding clamp PCNA 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA polymerase IV, ... 著者 Ling, H. 登録日 2008-11-26 公開日 2009-01-20 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural insight into recruitment of translesion DNA polymerase Dpo4 to sliding clamp PCNA Mol.Microbiol., 71, 2009
6MDW	Mechanism of protease dependent DPC repair 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, CITRATE ANION, ... 著者 Li, F, Raczynska, J, Chen, Z, Yu, H. 登録日 2018-09-05 公開日 2019-04-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural Insight into DNA-Dependent Activation of Human Metalloprotease Spartan. Cell Rep, 26, 2019
9E8P	Crystal Structure of GABARAP-ATG3 conjugate 分子名称: 1,2-ETHANEDIOL, Gamma-aminobutyric acid receptor-associated protein, SULFATE ION, ... 著者 Ohashi, K, Otomo, T. 登録日 2024-11-05 公開日 2025-08-06 最終更新日 2025-08-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural Insights into the GABARAP-ATG3 Backside Interaction and Apo ATG3 Conformation. Biochemistry, 64, 2025
7G9P	PanDDA analysis group deposition -- Crystal Structure of Zika virus NS3 Helicase in complex with Z1619958679 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 3-fluoro-N-(2-hydroxy-6-methylphenyl)pyridine-4-carboxamide, ... 著者 Godoy, A.S, Noske, G.D, Fairhead, M, Lithgo, R.M, Koekemoer, L, Aschenbrenner, J.C, Balcomb, B.H, Marples, P.G, Ni, X, Tomlinson, C.W.E, Wild, C, Mesquita, N.C.M.R, Oliva, G, Fearon, D, Walsh, M.A, von Delft, F. 登録日 2023-07-03 公開日 2023-07-26 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.743 Å) 主引用文献 PanDDA analysis group deposition To Be Published
4CZT	Crystal structure of the kinase domain of CIPK23 分子名称: 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, CBL-INTERACTING SERINE/THREONINE-PROTEIN KINASE 23, SULFATE ION 著者 Chaves-Sanjuan, A, Sanchez-Barrena, M.J, Albert, A. 登録日 2014-04-22 公開日 2014-10-15 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural Basis of the Regulatory Mechanism of the Plant Cipk Family of Protein Kinases Controlling Ion Homeostasis and Abiotic Stress Proc.Natl.Acad.Sci.USA, 111, 2014
1ASU	AVIAN SARCOMA VIRUS INTEGRASE CATALYTIC CORE DOMAIN CRYSTALLIZED FROM 2% PEG 400, 2M AMMONIUM SULFATE, HEPES PH 7.5 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AVIAN SARCOMA VIRUS INTEGRASE 著者 Bujacz, G, Jaskolski, M, Alexandratos, J, Wlodawer, A. 登録日 1995-08-25 公開日 1995-11-14 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 High-resolution structure of the catalytic domain of avian sarcoma virus integrase. J.Mol.Biol., 253, 1995
7TQO	Structure of human TREX1 分子名称: Three-prime repair exonuclease 1 著者 Zhou, W, Richmond-Buccola, D, Kranzusch, P.J. 登録日 2022-01-26 公開日 2022-08-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Structural basis of human TREX1 DNA degradation and autoimmune disease. Nat Commun, 13, 2022
7TQN	Structure of human TREX1 分子名称: Three-prime repair exonuclease 1 著者 Zhou, W, Richmond-Buccola, D, Kranzusch, P.J. 登録日 2022-01-26 公開日 2022-08-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis of human TREX1 DNA degradation and autoimmune disease. Nat Commun, 13, 2022
9E9B	Crystal structure of L. monocytogenes MenD with Mg2+ and ThDP bound 分子名称: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, MAGNESIUM ION, THIAMINE DIPHOSPHATE 著者 Klein, M, Given, F.M, Ho, N.A.T, Allison, T.M, Johnston, J.M. 登録日 2024-11-08 公開日 2025-07-30 最終更新日 2025-08-13 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Structures of Listeria monocytogenes MenD in ThDP-bound and in-crystallo captured intermediate I-bound forms. Acta Crystallogr.,Sect.F, 81, 2025
6LYK	Crystal Structure of R1263A mutant of Formylglycinamidine Synthetase 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLUTAMINE, ... 著者 Sharma, N, Tanwar, A.S, Anand, R. 登録日 2020-02-14 公開日 2021-02-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Mechanism of Coordinated Gating and Signal Transduction in Purine Biosynthetic Enzyme Formylglycinamidine Synthetase. Acs Catalysis, 12, 2022
5WBU	Crystal structure of mTOR(deltaN)-mLST8-PRAS40(alpha-helix & beta-strand) complex 分子名称: Proline-rich AKT1 substrate 1, Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8 著者 Pavletich, N.P, Yang, H. 登録日 2017-06-29 公開日 2017-12-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.42 Å) 主引用文献 Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40. Nature, 552, 2017
7TQP	Structure of human TREX1 分子名称: SULFATE ION, Three-prime repair exonuclease 1 著者 Zhou, W, Richmond-Buccola, D, Kranzusch, P.J. 登録日 2022-01-26 公開日 2022-08-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural basis of human TREX1 DNA degradation and autoimmune disease. Nat Commun, 13, 2022
5C9O	Crystal structure of recombinant PLL lectin from Photorhabdus luminescens at 1.5 A resolution 分子名称: GLYCEROL, PLL lectin 著者 Kumar, A, Sykorova, P, Demo, G, Dobes, P, Hyrsl, P, Wimmerova, M. 登録日 2015-06-28 公開日 2016-10-19 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 A Novel Fucose-binding Lectin from Photorhabdus luminescens (PLL) with an Unusual Heptabladed beta-Propeller Tetrameric Structure. J.Biol.Chem., 291, 2016
2R9L	Polymerase Domain from Mycobacterium tuberculosis Ligase D in complex with DNA 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*DGP*DCP*DCP*DGP*DCP*DAP*DAP*DCP*DGP*DCP*DA)-3'), ... 著者 Brissett, N.C, Fox, G.C, Pitcher, R.S, Doherty, A.J. 登録日 2007-09-13 公開日 2008-01-08 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of a NHEJ polymerase-mediated DNA synaptic complex Science, 318, 2007

<2184218521862187218821892190219121922193219421952196219721982199>