3ZI4
 
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4R39
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2EGU
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1OOY
 | | SUCCINYL-COA:3-KETOACID COA TRANSFERASE FROM PIG HEART | | 分子名称: | PHOSPHATE ION, POTASSIUM ION, Succinyl-CoA:3-ketoacid-coenzyme A transferase, ... | | 著者 | Coros, A.M, Swenson, L, Wolodko, W.T, Fraser, M.E. | | 登録日 | 2003-03-04 | | 公開日 | 2004-04-27 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure of the CoA transferase from pig heart to 1.7 A resolution.
Acta Crystallogr.,Sect.D, 60, 2004
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3WZT
 | | Crystal structure of Trx3 domain of UGGT (detergent-unbound form) | | 分子名称: | UDP-glucose-glycoprotein glucosyltransferase-like protein | | 著者 | Zhu, T, Satoh, T, Kato, K. | | 登録日 | 2014-10-03 | | 公開日 | 2014-12-03 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structural insight into substrate recognition by the endoplasmic reticulum folding-sensor enzyme: crystal structure of third thioredoxin-like domain of UDP-glucose:glycoprotein glucosyltransferase
Sci Rep, 4, 2014
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4IRR
 | | Crystal Structure of C.elegans Thymidylate Synthase in Complex with dUMP | | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Thymidylate synthase | | 著者 | Wilk, P, Dowiercial, A, Banaszak, K, Jarmula, A, Rypniewski, W, Rode, W. | | 登録日 | 2013-01-15 | | 公開日 | 2014-01-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Crystal Structure of C.elegans Thymidylate Synthase in Complex with dUMP
To be Published
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4ISK
 | | Crystal structure of E.coli thymidylate synthase with dUMP and the BGC 945 inhibitor | | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2'-deoxy-5'-uridylic acid, MAGNESIUM ION, ... | | 著者 | Tochowicz, A, Finer-Moore, J, Stroud, R.M. | | 登録日 | 2013-01-16 | | 公開日 | 2013-12-25 | | 最終更新日 | 2014-02-12 | | 実験手法 | X-RAY DIFFRACTION (1.752 Å) | | 主引用文献 | Development and Binding Mode Assessment of N-[4-[2-Propyn-1-yl[(6S)-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-3H-cyclopenta[g]quinazolin-6-yl]amino]benzoyl]-l-gamma-glutamyl-d-glutamic Acid (BGC 945), a Novel Thymidylate Synthase Inhibitor That Targets Tumor Cells.
J.Med.Chem., 56, 2013
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1XET
 | | Crystal structure of stilbene synthase from Pinus sylvestris, complexed with methylmalonyl CoA | | 分子名称: | 3-(1H-INDOL-3-YL)-2-OXOPROPANOIC ACID, Dihydropinosylvin synthase, METHYLMALONYL-COENZYME A | | 著者 | Ng, S.H, Chirgadze, D, Spiteller, D, Li, T.L, Spencer, J.B, Blundell, T.L. | | 登録日 | 2004-09-12 | | 公開日 | 2006-04-11 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of stilbene synthase from Pinus sylvestris, complexed with methylmalonyl CoA
To be Published
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3X43
 | | Crystal structure of O-ureido-L-serine synthase | | 分子名称: | O-ureido-L-serine synthase, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Matoba, Y, Uda, N, Oda, K, Sugiyama, M. | | 登録日 | 2015-03-13 | | 公開日 | 2015-07-29 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | The structural and mutational analyses of O-ureido-L-serine synthase necessary for D-cycloserine biosynthesis.
Febs J., 282, 2015
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1XVT
 | | Crystal Structure of Native CaiB in complex with coenzyme A | | 分子名称: | COENZYME A, Crotonobetainyl-CoA:carnitine CoA-transferase | | 著者 | Rangarajan, E.S, Li, Y, Iannuzzi, P, Cygler, M, Matte, A. | | 登録日 | 2004-10-28 | | 公開日 | 2005-03-15 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structure of Escherichia coli Crotonobetainyl-CoA: Carnitine CoA-Transferase (CaiB) and Its Complexes with CoA and Carnitinyl-CoA.
Biochemistry, 44, 2005
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1OGV
 | | Lipidic cubic phase crystal structure of the photosynthetic reaction centre from Rhodobacter sphaeroides | | 分子名称: | BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, CARDIOLIPIN, ... | | 著者 | Katona, G, Andreasson, U, Landau, E.M, Andreasson, L.-E, Neutze, R. | | 登録日 | 2003-05-13 | | 公開日 | 2003-08-05 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Lipidic Cubic Phase Crystal Structure of the Photosynthetic Reaction Centre from Rhodobacter Sphaeroides at 2.35 A Resolution
J.Mol.Biol., 331, 2003
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3ZET
 | | Structure of a Salmonella typhimurium YgjD-YeaZ heterodimer. | | 分子名称: | ADENOSINE MONOPHOSPHATE, CADMIUM ION, PROBABLE TRNA THREONYLCARBAMOYLADENOSINE BIOSYNTHESIS PROTEIN GCP, ... | | 著者 | Nichols, C.E, Lamb, H.K, Thompson, P, El Omari, K, Lockyer, M, Charles, I, Hawkins, A.R, Stammers, D.K. | | 登録日 | 2012-12-07 | | 公開日 | 2013-03-20 | | 最終更新日 | 2013-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Crystal Structure of the Dimer of Two Essential Salmonella Typhimurium Proteins, Ygjd & Yeaz and Calorimetric Evidence for the Formation of a Ternary Ygjd-Yeaz-Yjee Complex.
Protein Sci., 22, 2013
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4R87
 | | Crystal structure of spermidine N-acetyltransferase from Vibrio cholerae in complex with CoA and spermine | | 分子名称: | COENZYME A, DI(HYDROXYETHYL)ETHER, SPERMINE, ... | | 著者 | Filippova, E.V, Minasov, G, Kiryukhina, O, Kuhn, M.L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2014-08-29 | | 公開日 | 2015-03-25 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | A Novel Polyamine Allosteric Site of SpeG from Vibrio cholerae Is Revealed by Its Dodecameric Structure.
J.Mol.Biol., 427, 2015
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3B1P
 | | Structure of Burkholderia thailandensis nucleoside kinase (BthNK) in complex with ADP-inosine | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, INOSINE, Ribokinase, ... | | 著者 | Yasutake, Y, Ota, H, Hino, E, Sakasegawa, S, Tamura, T. | | 登録日 | 2011-07-05 | | 公開日 | 2011-11-02 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structures of Burkholderia thailandensis nucleoside kinase: implications for the catalytic mechanism and nucleoside selectivity
Acta Crystallogr.,Sect.D, 67, 2011
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4IQB
 | | High Resolution Crystal Structure of C.elegans Thymidylate Synthase | | 分子名称: | SULFATE ION, Thymidylate synthase | | 著者 | Wilk, P, Dowiercial, A, Banaszak, K, Jarmula, A, Rypniewski, W, Rode, W. | | 登録日 | 2013-01-11 | | 公開日 | 2014-01-22 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.13 Å) | | 主引用文献 | Crystal structures of nematode (parasitic T. spiralis and free living C. elegans), compared to mammalian, thymidylate synthases (TS). Molecular docking and molecular dynamics simulations in search for nematode-specific inhibitors of TS.
J. Mol. Graph. Model., 77, 2017
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5W8O
 | | Homoserine transacetylase MetX from Mycobacterium hassiacum | | 分子名称: | CALCIUM ION, GLYCEROL, Homoserine O-acetyltransferase, ... | | 著者 | Reed, R.W, Rodriguez, E.S, Li, J, Korotkov, K.V. | | 登録日 | 2017-06-22 | | 公開日 | 2017-07-12 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | | 主引用文献 | Structural analysis of mycobacterial homoserine transacetylases central to methionine biosynthesis reveals druggable active site.
Sci Rep, 9, 2019
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1M1T
 | | Biosynthetic thiolase, Q64A mutant | | 分子名称: | Acetyl-CoA acetyltransferase, GLYCEROL, SULFATE ION | | 著者 | Kursula, P, Ojala, J, Lambeir, A.-M, Wierenga, R.K. | | 登録日 | 2002-06-20 | | 公開日 | 2002-11-29 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | The catalytic cycle of biosynthetic thiolase: A conformational
journey of an acetyl group through four binding modes and two oxyanion holes
Biochemistry, 41, 2002
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3ZBK
 | | Crystal structure of SCP2 thiolase from Leishmania mexicana: The C123A mutant. | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3-KETOACYL-COA THIOLASE-LIKE PROTEIN, CHLORIDE ION, ... | | 著者 | Harijan, R.K, Kiema, T.-R, Weiss, M.S, Michels, P.A.M, Wierenga, R.K. | | 登録日 | 2012-11-10 | | 公開日 | 2013-08-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal Structures of Scp2-Thiolases of Trypanosomatidae, Human Pathogens Causing Widespread Tropical Diseases: The Importance for Catalysis of the Cysteine of the Unique Hdcf Loop.
Biochem.J., 455, 2013
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3B9H
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1M3Z
 | | Biosynthetic thiolase, C89A mutant, complexed with acetyl coenzyme A | | 分子名称: | ACETYL COENZYME *A, Acetyl-CoA acetyltransferase, SULFATE ION | | 著者 | Kursula, P, Ojala, J, Lambeir, A.-M, Wierenga, R.K. | | 登録日 | 2002-07-03 | | 公開日 | 2002-11-29 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | The catalytic cycle of biosynthetic thiolase: A conformational
journey of an acetyl group through four binding modes and two oxyanion holes
Biochemistry, 41, 2002
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4LS7
 | | Crystal structure of Bacillus subtilis beta-ketoacyl-ACP synthase II (FabF) in a non-covalent complex with cerulenin | | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] synthase 2, Cerulenin, GLYCEROL, ... | | 著者 | Trajtenberg, F, Larrieux, N, Buschiazzo, A. | | 登録日 | 2013-07-22 | | 公開日 | 2014-04-02 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.674 Å) | | 主引用文献 | Structural insights into bacterial resistance to cerulenin.
Febs J., 281, 2014
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4H99
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4HBH
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5XUN
 | | Crystal structure of Y145F mutant of KacT | | 分子名称: | ACETATE ION, ACETYL COENZYME *A, Acetyltransferase | | 著者 | Qian, H.L, Yao, Q.Q, Gan, J.H, Ou, H.Y. | | 登録日 | 2017-06-23 | | 公開日 | 2017-07-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Identification and characterization of acetyltransferase-type toxin-antitoxin locus in Klebsiella pneumoniae
Mol. Microbiol., 108, 2018
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1FJ4
 | | THE STRUCTURE OF BETA-KETOACYL-[ACYL CARRIER PROTEIN] SYNTHASE I IN COMPLEX WITH THIOLACTOMYCIN, IMPLICATIONS FOR DRUG DESIGN | | 分子名称: | BETA-KETOACYL-[ACYL CARRIER PROTEIN] SYNTHASE I, THIOLACTOMYCIN | | 著者 | Price, A.C, Choi, K, Heath, R.J, Li, Z, White, S.W, Rock, C.O. | | 登録日 | 2000-08-07 | | 公開日 | 2000-08-23 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Inhibition of beta-ketoacyl-acyl carrier protein synthases by thiolactomycin and cerulenin. Structure and mechanism.
J.Biol.Chem., 276, 2001
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