PDB: 5653 件ウェブページステータス検索Chemie searchBIRD

---

7TX7	Cryo-EM structure of the human reduced folate carrier 分子名称: Digitonin, Reduced folate transporter,Soluble cytochrome b562 著者 Wright, N.J, Fedor, J.G, Lee, S.-Y. 登録日 2022-02-07 公開日 2022-09-21 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Methotrexate recognition by the human reduced folate carrier SLC19A1. Nature, 609, 2022
7TX6	Cryo-EM structure of the human reduced folate carrier in complex with methotrexate 分子名称: Digitonin, METHOTREXATE, Reduced folate transporter,Soluble cytochrome b562 著者 Wright, N.J, Fedor, J.G, Lee, S.-Y. 登録日 2022-02-07 公開日 2022-09-21 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Methotrexate recognition by the human reduced folate carrier SLC19A1. Nature, 609, 2022
7U0M	Crystal structure of a enoyl-[acyl-carrier-protein] reductase (InhA) from Mycobacterium abscessus bound to NAD and NITD-916 分子名称: 6-[(4,4-dimethylcyclohexyl)methyl]-4-hydroxy-3-phenylpyridin-2(1H)-one, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2022-02-18 公開日 2022-10-05 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Efficacy and Mode of Action of a Direct Inhibitor of Mycobacterium abscessus InhA. Acs Infect Dis., 8, 2022
1NZK	Crystal Structure of a Multiple Mutant (L44F, L73V, V109L, L111I, C117V) of Human Acidic Fibroblast Growth Factor 分子名称: Acidic Fibroblast Growth Factor, FORMIC ACID, SULFATE ION 著者 Brych, S.R, Kim, J, Logan, T.M, Blaber, M. 登録日 2003-02-18 公開日 2004-03-02 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Accommodation of a highly symmetric core within a symmetric protein superfold. Protein Sci., 12, 2003
1KJI	Crystal structure of glycinamide ribonucleotide transformylase in complex with Mg-AMPPCP 分子名称: 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CHLORIDE ION, ... 著者 Thoden, J.B, Firestine, S.M, Benkovic, S.J, Holden, H.M. 登録日 2001-12-04 公開日 2002-06-28 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 PurT-encoded glycinamide ribonucleotide transformylase. Accommodation of adenosine nucleotide analogs within the active site. J.Biol.Chem., 277, 2002
3BM5	Crystal structure of O-acetyl-serine sulfhydrylase from Entamoeba histolytica in complex with cysteine 分子名称: CYSTEINE, Cysteine synthase, PYRIDOXAL-5'-PHOSPHATE, ... 著者 Krishna, C, Kumar, M, Kumar, S, Gourinath, S. 登録日 2007-12-12 公開日 2008-04-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of native O-acetyl-serine sulfhydrylase from Entamoeba histolytica and its complex with cysteine: structural evidence for cysteine binding and lack of interactions with serine acetyl transferase. Proteins, 72, 2008
4C6F	Crystal structure of the dihydroorotase domain of human CAD bound to substrate at pH 6.5 分子名称: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, DIHYDROOROTASE, FORMIC ACID, ... 著者 Ramon-Maiques, S, Lallous, N, Grande-Garcia, A. 登録日 2013-09-18 公開日 2014-02-05 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.261 Å) 主引用文献 Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad. Structure, 22, 2014
1KGP	R2F from Corynebacterium Ammoniagenes in its Mn substituted form 分子名称: MANGANESE (II) ION, Ribonucleotide reductase protein R2F 著者 Hogbom, M, Huque, Y, Sjoberg, B.M, Nordlund, P. 登録日 2001-11-28 公開日 2001-12-21 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of the di-iron/radical protein of ribonucleotide reductase from Corynebacterium ammoniagenes. Biochemistry, 41, 2002
1KJ9	Crystal structure of purt-encoded glycinamide ribonucleotide transformylase complexed with Mg-ATP 分子名称: 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Thoden, J.B, Firestine, S.M, Benkovic, S.J, Holden, H.M. 登録日 2001-12-04 公開日 2002-06-28 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 PurT-encoded glycinamide ribonucleotide transformylase. Accommodation of adenosine nucleotide analogs within the active site. J.Biol.Chem., 277, 2002
1KSZ	ENTRAPMENT OF 6-THIOPHOSPHORYL-IMP IN THE ACTIVE SITE OF CRYSTALLINE ADENYLOSUCCINATE SYNTHETASE FROM ESCHERICHIA COLI, DATA COLLECTED AT 298K 分子名称: 2-DEAZO-6-THIOPHOSPHATE GUANOSINE-5'-MONOPHOSPHATE, ADENYLOSUCCINATE SYNTHETASE, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Poland, B.W, Bruns, C.A, Fromm, H.J, Honzatko, R.B. 登録日 1997-01-14 公開日 1997-10-08 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Entrapment of 6-thiophosphoryl-IMP in the active site of crystalline adenylosuccinate synthetase from Escherichia coli. J.Biol.Chem., 272, 1997
1KJ8	Crystal Structure of PurT-Encoded Glycinamide Ribonucleotide Transformylase in Complex with Mg-ATP and GAR 分子名称: 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Thoden, J.B, Firestine, S.M, Benkovic, S.J, Holden, H.M. 登録日 2001-12-04 公開日 2002-06-28 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 PurT-encoded glycinamide ribonucleotide transformylase. Accommodation of adenosine nucleotide analogs within the active site. J.Biol.Chem., 277, 2002
1LNY	Crystal structure of the recombinant mouse-muscle adenylosuccinate synthetase complexed with 6-phosphoryl-IMP, GDP and Mg 分子名称: 6-O-PHOSPHORYL INOSINE MONOPHOSPHATE, Adenylosuccinate Synthetase, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Iancu, C.V, Borza, T, Fromm, H.J, Honzatko, R.B. 登録日 2002-05-04 公開日 2002-08-28 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 IMP, GTP, and 6-phosphoryl-IMP complexes of recombinant mouse muscle adenylosuccinate synthetase. J.Biol.Chem., 277, 2002
4C5J	Structure of the pyridoxal kinase from Staphylococcus aureus 分子名称: PHOSPHOMETHYLPYRIMIDINE KINASE, SULFATE ION 著者 Nodwell, M, Alte, F, Sieber, S.A, Schneider, S. 登録日 2013-09-12 公開日 2014-03-19 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 A Subfamily of Bacterial Ribokinases Utilizes a Hemithioacetal for Pyridoxal Phosphate Salvage. J.Am.Chem.Soc., 136, 2014
3HCX	Crystal structure of E. coli HPPK(N10A) 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, CHLORIDE ION 著者 Blaszczyk, J, Li, Y, Yan, H, Ji, X. 登録日 2009-05-06 公開日 2010-05-19 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Role of loop coupling in enzymatic catalysis and conformational dynamics To be Published
1OGH	Structure of the bifunctional dCTP deaminase-dUTPase from Methanocaldococcus jannaschii 分子名称: BIFUNCTIONAL DEAMINASE/DIPHOSPHATASE 著者 Johansson, E, Bjornberg, O, Nyman, P.O, Larsen, S. 登録日 2003-05-02 公開日 2003-06-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Structure of the Bifunctional Dctp Deaminase-Dutpase from Methanocaldococcus Jannaschii and its Relation to Other Homotrimeric Dutpases J.Biol.Chem., 278, 2003
3BL3	tRNA guanine transglycosylase V233G mutant apo structure 分子名称: GLYCEROL, Queuine tRNA-ribosyltransferase, ZINC ION 著者 Tidten, N, Heine, A, Reuter, K, Klebe, G. 登録日 2007-12-10 公開日 2008-12-16 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Investigation of Specificity Determinants in Bacterial tRNA-Guanine Transglycosylase Reveals Queuine, the Substrate of Its Eucaryotic Counterpart, as Inhibitor Plos One, 8, 2013
1QGN	CYSTATHIONINE GAMMA-SYNTHASE FROM NICOTIANA TABACUM 分子名称: PROTEIN (CYSTATHIONINE GAMMA-SYNTHASE), PYRIDOXAL-5'-PHOSPHATE 著者 Steegborn, C, Messerschmidt, A, Laber, B, Streber, W, Huber, R, Clausen, T. 登録日 1999-05-02 公開日 1999-08-25 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The crystal structure of cystathionine gamma-synthase from Nicotiana tabacum reveals its substrate and reaction specificity. J.Mol.Biol., 290, 1999
1QF9	PH INFLUENCES FLUORIDE COORDINATION NUMBER OF THE ALFX PHOSPHORYL TRANSFER TRANSITION STATE ANALOG IN UMP/CMP KINASE 分子名称: ADENOSINE-5'-DIPHOSPHATE, CYTIDINE-5'-MONOPHOSPHATE, MAGNESIUM ION, ... 著者 Schlichting, I, Reinstein, J. 登録日 1999-04-07 公開日 1999-08-16 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 pH influences fluoride coordination number of the AlFx phosphoryl transfer transition state analog. Nat.Struct.Biol., 6, 1999
3TP4	Crystal Structure of engineered protein at the resolution 1.98A, Northeast Structural Genomics Consortium Target OR128 分子名称: ACETIC ACID, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... 著者 Kuzin, A, Su, M, Seetharaman, J, Rajagopalan, S, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Baker, D, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) 登録日 2011-09-07 公開日 2011-10-05 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.979 Å) 主引用文献 Design of activated serine-containing catalytic triads with atomic-level accuracy. Nat.Chem.Biol., 10, 2014
1JKX	Unexpected formation of an epoxide-derived multisubstrate adduct inhibitor on the active site of GAR transformylase 分子名称: N-[5'-O-PHOSPHONO-RIBOFURANOSYL]-2-[2-HYDROXY-2-[4-[GLUTAMIC ACID]-N-CARBONYLPHENYL]-3-[2-AMINO-4-HYDROXY-QUINAZOLIN-6-YL]-PROPANYLAMINO]-ACETAMIDE, PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE 著者 Greasley, S.E, Marsilje, T.H, Cai, H, Baker, S, Benkovic, S.J, Boger, D.L, Wilson, I.A. 登録日 2001-07-13 公開日 2001-11-30 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Unexpected formation of an epoxide-derived multisubstrate adduct inhibitor on the active site of GAR transformylase. Biochemistry, 40, 2001
3BLL	TGT mutant in complex with Boc-preQ1 分子名称: GLYCEROL, Queuine tRNA-ribosyltransferase, ZINC ION, ... 著者 Tidten, N, Heine, A, Reuter, K, Klebe, G. 登録日 2007-12-11 公開日 2008-12-16 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.26 Å) 主引用文献 Investigation of Specificity Determinants in Bacterial tRNA-Guanine Transglycosylase Reveals Queuine, the Substrate of Its Eucaryotic Counterpart, as Inhibitor Plos One, 8, 2013
1P63	Human Acidic Fibroblast Growth Factor. 140 Amino Acid Form with Amino Terminal His Tag and Leu111 Replaced with Ile (L111I) 分子名称: ACIDIC FIBROBLAST GROWTH FACTOR, FORMIC ACID, SULFATE ION 著者 Brych, S.R, Kim, J, Logan, T.M, Blaber, M. 登録日 2003-04-28 公開日 2004-05-11 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Accommodation of a highly symmetric core within a symmetric protein superfold Protein Sci., 12, 2003
3BLO	TGT mutant in complex with queuine 分子名称: 2-amino-5-({[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino}methyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, GLYCEROL, Queuine tRNA-ribosyltransferase, ... 著者 Tidten, N, Heine, A, Reuter, K, Klebe, G. 登録日 2007-12-11 公開日 2008-12-16 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Investigation of Specificity Determinants in Bacterial tRNA-Guanine Transglycosylase Reveals Queuine, the Substrate of Its Eucaryotic Counterpart, as Inhibitor Plos One, 8, 2013
3C1P	Crystal Structure of an alternating D-Alanyl, L-Homoalanyl PNA 分子名称: Peptide Nucleic Acid DLY-HGL-AGD-LHC-AGD-LHC-CUD-LYS 著者 Cuesta-Seijo, J.A, Sheldrick, G.M, Zhang, J, Diederichsen, U. 登録日 2008-01-23 公開日 2009-01-27 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 Continuous beta-turn fold of an alternating alanyl/homoalanyl peptide nucleic acid. Acta Crystallogr.,Sect.D, 68, 2012
3BLD	tRNA guanine transglycosylase V233G mutant preQ1 complex structure 分子名称: 7-DEAZA-7-AMINOMETHYL-GUANINE, GLYCEROL, Queuine tRNA-ribosyltransferase, ... 著者 Tidten, N, Heine, A, Reuter, K, Klebe, G. 登録日 2007-12-11 公開日 2008-12-16 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.19 Å) 主引用文献 Investigation of Specificity Determinants in Bacterial tRNA-Guanine Transglycosylase Reveals Queuine, the Substrate of Its Eucaryotic Counterpart, as Inhibitor Plos One, 8, 2013

<212213214215216217218219220221222223224225226227>