PDB: 37044 件ウェブページステータス検索Chemie searchBIRD

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6MNH	ULK1 Unc-51 like autophagy activating kinase in complex with inhibitor BTC 分子名称: CHLORIDE ION, DIMETHYL SULFOXIDE, N-[(2R)-3-methylbutan-2-yl]-1H-benzotriazole-6-carboxamide, ... 著者 Hendle, J, Sauder, J.M, Hickey, M.J, Rauch, C.T, Maletic, M, Schwinn, K.D. 登録日 2018-10-01 公開日 2019-03-27 最終更新日 2019-11-13 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Idea2Data: Toward a New Paradigm for Drug Discovery. Acs Med.Chem.Lett., 10, 2019
8OUQ	Clr-11 from Rattus norvegicus 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C-type lectin domain family 2 member D11 著者 Skalova, T, Blaha, J, Kalouskova, B, Skorepa, O, Vanek, O, Dohnalek, J. 登録日 2023-04-24 公開日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Clr-11 from Rattus norvegicus To Be Published
6MQI	Crystal Structure of the All-trans Retinal bound R111K:Y134F:T54V:R132Q:P39Y:R59Y:L121Q mutant of Human Cellular Retinoic Acid Binding Protein II Irradiated with 400 nm Laser for 5 minutes at 1.87 Angstrom Resolution 分子名称: Cellular retinoic acid-binding protein 2, RETINAL 著者 Ghanbarpour, A, Geiger, J. 登録日 2018-10-09 公開日 2019-01-09 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Mimicking Microbial Rhodopsin Isomerization in a Single Crystal. J. Am. Chem. Soc., 141, 2019
6BZS	Human ABCC6 NBD1 in Apo state 分子名称: Multidrug resistance-associated protein 6, SULFATE ION 著者 Zheng, A, Thibodeau, P.H. 登録日 2017-12-26 公開日 2018-09-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.29990458 Å) 主引用文献 Structural analysis reveals pathomechanisms associated with pseudoxanthoma elasticum-causing mutations in the ABCC6 transporter. J. Biol. Chem., 293, 2018
6MQV	Structure of HEWL from LCP injector using synchrotron radiation 分子名称: Lysozyme C, SODIUM ION 著者 Caradoc-Davies, T.T, Aishima, J, Berntsen, P, Hadian-Jazi, M. 登録日 2018-10-10 公開日 2019-09-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The serial millisecond crystallography instrument at the Australian Synchrotron incorporating the "Lipidico" injector. Rev Sci Instrum, 90, 2019
6MQZ	Crystal Structure of the 13-cis Product of the All-trans Retinal-Bound R111K:Y134F:T54V:R132Q:P39Y:R59Y:L121E Mutant of Human Cellular Retinoic Acid Binding Protein II Irradiated with 400 nm Laser (5 minutes) at 2.07 Angstrom 分子名称: Cellular retinoic acid-binding protein 2, GLYCEROL, RETINAL 著者 Ghanbarpour, A, Geiger, J. 登録日 2018-10-11 公開日 2019-01-09 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Mimicking Microbial Rhodopsin Isomerization in a Single Crystal. J. Am. Chem. Soc., 141, 2019
8OUK	Arf GTPase from the asgard Hodarchaea : HodArfR1 bound to GTP 分子名称: Arf GTPase, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION 著者 Menetrey, J, Jackson, C, Dacks, J, Elias, M, Vargova, R. 登録日 2023-04-23 公開日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Arf Family GTPases are present in Asgard archaea To Be Published
6MQX	Crystal Structure of All-trans Retinal-Bound R111K:Y134F:T54V:R132Q:P39Y:R59Y:L121E Human Cellular Retinoic Acid Binding Protein II Irradiated with 400 nm Laser (30 seconds) and Subsequently Dark Adapted (25 minutes) at 2.0 Angstrom Resolution 分子名称: Cellular retinoic acid-binding protein 2, GLYCEROL, RETINAL 著者 Ghanbarpour, A, Geiger, J. 登録日 2018-10-11 公開日 2019-01-09 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Mimicking Microbial Rhodopsin Isomerization in a Single Crystal. J. Am. Chem. Soc., 141, 2019
8OUN	Arf GTPase from the asgard Gerdarchaea : GerdArfR1 bound to GDP 分子名称: GTP-binding protein, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION 著者 Menetrey, J, Jackson, C, Dacks, J.B, Elias, M, Vargova, R. 登録日 2023-04-24 公開日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.653 Å) 主引用文献 Arf Family GTPases are present in Asgard archaea To Be Published
6MS9	GDP-bound KRAS P34R mutant 分子名称: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION 著者 Bera, A.K, Westover, K.D. 登録日 2018-10-16 公開日 2020-04-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 GTP hydrolysis is modulated by Arg34 in the RASopathy-associated KRASP34R. Birth Defects Res, 112, 2020
8P7G	Structural characterization of PHOX2B and its DNA interactions shed lights into the molecular basis of the + 7Ala variant pathogenicity in CCHS 分子名称: Paired mesoderm homeobox protein 2B 著者 Russo, L, Diana, D, Fattorusso, R. 登録日 2023-05-30 公開日 2024-05-15 最終更新日 2024-06-26 実験手法 SOLUTION NMR 主引用文献 Structural characterization of PHOX2B and its DNA interaction shed light on the molecular basis of the +7Ala variant pathogenicity in CCHS. Chem Sci, 15, 2024
8OUL	Arf GTPase from the asgard Hodarchaea : HodArfR1 bound to GDP 分子名称: Arf GTPase, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION 著者 Menetrey, J, Jackson, C. 登録日 2023-04-23 公開日 2024-05-01 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Arf Family GTPases are present in Asgard archaea To Be Published
5JLF	Structure of the F-actin-tropomyosin complex (Reprocessed) 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 von der Ecken, J, Raunser, S. 登録日 2016-04-27 公開日 2016-06-15 最終更新日 2020-02-12 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution. Nature, 534, 2016
6C7Z	Crystal structure of the Q108K:K40L:T51V:R58F mutant of human Cellular Retinol Binding Protein II in complex with synthetic Ligand Julolidine 分子名称: (2E,4E)-3-methyl-5-(2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-9-yl)penta-2,4-dienal, ACETATE ION, Retinol-binding protein 2 著者 Nosrati, M, Geiger, J.H. 登録日 2018-01-23 公開日 2018-04-25 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 A Genetically Encoded Ratiometric pH Probe: Wavelength Regulation-Inspired Design of pH Indicators. Chembiochem, 19, 2018
8OSN	GTPASE HRAS IN COMPLEX WITH ZN-CYCLEN AT AMBIENT PRESSURE 分子名称: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Colloc'h, N, Prange, T, Girard, E, Kalbitzer, H.R. 登録日 2023-04-19 公開日 2024-05-08 最終更新日 2024-07-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 High Pressure Promotes Binding of the Allosteric Inhibitor Zn 2+ -Cyclen in Crystals of Activated H-Ras. Chemistry, 30, 2024
6C93	Effects of the E310A Mutation of Cytochrome P450 4B1 (CYP4B1) on n-Octane binding and Heme Ruffling 分子名称: Cytochrome P450 4B1, N-OCTANE, PROTOPORPHYRIN IX CONTAINING FE 著者 Hsu, M.-H, Johnson, E.F. 登録日 2018-01-25 公開日 2018-06-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.674 Å) 主引用文献 Noncovalent interactions dominate dynamic heme distortion in cytochrome P450 4B1. J. Biol. Chem., 293, 2018
5L92	The 2.1 A crystal structure of CYP109E1 from Bacillus megaterium in complex with corticosterone 分子名称: CORTICOSTERONE, Cytochrome P450, MALONIC ACID, ... 著者 Jozwik, I.K, Thunnissen, A.M.W.H. 登録日 2016-06-09 公開日 2016-10-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis of steroid binding and oxidation by the cytochrome P450 CYP109E1 from Bacillus megaterium. Febs J., 283, 2016
8OSO	GTPase HRAS in complex with Zn-cyclen under 500 MPa pressure 分子名称: 1,4,7,10-tetraazacyclododecane, GTPase HRas, MAGNESIUM ION, ... 著者 Colloc'h, N, Prange, T, Girard, E, Kalbitzer, H.R. 登録日 2023-04-19 公開日 2024-05-08 最終更新日 2024-07-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 High Pressure Promotes Binding of the Allosteric Inhibitor Zn 2+ -Cyclen in Crystals of Activated H-Ras. Chemistry, 30, 2024
6N3I	Crystal structure of a double Trp XylE mutants (G58W/L315W) 分子名称: D-xylose transporter 著者 Jiang, X, Wu, J.P, Yan, N. 登録日 2018-11-15 公開日 2019-03-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.69 Å) 主引用文献 Engineered XylE as a tool for mechanistic investigation and ligand discovery of the glucose transporters GLUTs. Cell Discov, 5, 2019
8OSM	GTPASE HRAS IN COMPLEX WITH ZN-CYCLEN AT 200 MPA PRESSURE 分子名称: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Colloc'h, N, Girard, E, Prange, T, Kalbitzer, H.R. 登録日 2023-04-19 公開日 2024-05-08 最終更新日 2024-07-03 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 High Pressure Promotes Binding of the Allosteric Inhibitor Zn 2+ -Cyclen in Crystals of Activated H-Ras. Chemistry, 30, 2024
6N4T	Crystal structure of Matriptase1 in complex with a peptidomimetic benzothiazole 分子名称: ETHANOL, GLUTATHIONE, MAGNESIUM ION, ... 著者 Campobasso, N. 登録日 2018-11-20 公開日 2019-10-02 最終更新日 2019-12-04 実験手法 X-RAY DIFFRACTION (1.945 Å) 主引用文献 Discovery and Development of TMPRSS6 Inhibitors Modulating Hepcidin Levels in Human Hepatocytes. Cell Chem Biol, 26, 2019
5KXW	Hen Egg White Lysozyme at 278K, Data set 6 分子名称: Lysozyme C, SODIUM ION 著者 Russi, S, Gonzalez, A, Kenner, L.R, Keedy, D.A, Fraser, J.S, van den Bedem, H. 登録日 2016-07-20 公開日 2016-09-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Conformational variation of proteins at room temperature is not dominated by radiation damage. J Synchrotron Radiat, 24, 2017
6N6Q	Crystal structure of a Cytochrome P450 (CYP102L1) 分子名称: CACODYLATE ION, Cytochrome P450 (CYP102L1), PROTOPORPHYRIN IX CONTAINING FE 著者 Follmer, A.H, Poulos, T.L. 登録日 2018-11-26 公開日 2019-06-05 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 On the occurrence of cytochrome P450 in viruses. Proc.Natl.Acad.Sci.USA, 116, 2019
5L14	The crystal structure of neuraminidase from A/Shanghai/2/2013 (H7N9) influenza virus 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neuraminidase, ... 著者 Yang, H, Stevens, J. 登録日 2016-07-28 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Drug Susceptibility Evaluation of an Influenza A(H7N9) Virus by Analyzing Recombinant Neuraminidase Proteins. J. Infect. Dis., 216, 2017
5L1U	X-ray Structure of M81A mutant of Cytochrome P450 PntM with pentalenolactone F 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Pentalenolactone synthase, pentalenolactone F 著者 Duan, L, Jogl, G, Cane, D.E. 登録日 2016-07-29 公開日 2016-09-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.074 Å) 主引用文献 The Cytochrome P450-Catalyzed Oxidative Rearrangement in the Final Step of Pentalenolactone Biosynthesis: Substrate Structure Determines Mechanism. J.Am.Chem.Soc., 138, 2016

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