PDB: 19255 件ウェブページステータス検索Chemie searchBIRD

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2D2K	Crystal Structure of a minimal, native (U39) all-RNA hairpin ribozyme 分子名称: 5'-R(*CP*GP*GP*UP*GP*AP*GP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*G)-3', ... 著者 Alam, S, Grum-Tokars, V, Krucinska, J, Kundracik, M.L, Wedekind, J.E. 登録日 2005-09-11 公開日 2005-11-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Conformational heterogeneity at position U37 of an all-RNA hairpin ribozyme with implications for metal binding and the catalytic structure of the S-turn Biochemistry, 44, 2005
2D2L	Crystal Structure of a minimal, all-RNA hairpin ribozyme with a propyl linker (C3) at position U39 分子名称: 5'-R(*CP*GP*GP*UP*GP*AP*GP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*G)-3', ... 著者 Alam, S, Grum-Tokars, V, Krucinska, J, Kundracik, M.L, Wedekind, J.E. 登録日 2005-09-11 公開日 2005-11-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Conformational heterogeneity at position U37 of an all-RNA hairpin ribozyme with implications for metal binding and the catalytic structure of the S-turn Biochemistry, 44, 2005
2EXG	Making Protein-Protein Interactions Drugable: Discovery of Low-Molecular-Weight Ligands for the AF6 PDZ Domain 分子名称: (5R)-2-SULFANYL-5-[4-(TRIFLUOROMETHYL)BENZYL]-1,3-THIAZOL-4-ONE, Afadin 著者 Joshi, M, Vargas, C, Boisguerin, P, Krause, G, Schade, M, Oschkinat, H. 登録日 2005-11-08 公開日 2006-10-17 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Discovery of low-molecular-weight ligands for the AF6 PDZ domain. Angew.Chem.Int.Ed.Engl., 45, 2006
6I12	CRYSTAL STRUCTURE OF FASCIN IN COMPLEX WITH COMPOUND 5 分子名称: 2-[(4-chlorophenyl)methyl]-~{N}-(1-methylpyrazol-4-yl)-1-oxidanylidene-isoquinoline-4-carboxamide, ACETATE ION, Fascin 著者 Schuettelkopf, A.W. 登録日 2018-10-27 公開日 2019-02-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents. Bioorg.Med.Chem.Lett., 29, 2019
8OUY	Human RAD51B-RAD51C-RAD51D-XRCC2 (BCDX2) complex, 3.4 A resolution 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA repair protein RAD51 homolog 2, ... 著者 Greenhough, L.A, Liang, C.C, West, S.C. 登録日 2023-04-25 公開日 2023-06-21 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structure and function of the RAD51B-RAD51C-RAD51D-XRCC2 tumour suppressor. Nature, 619, 2023
8OUZ	Human RAD51B-RAD51C-RAD51D-XRCC2 (BCDX2) complex, 2.2 A resolution 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA repair protein RAD51 homolog 2, ... 著者 Greenhough, L.A, Liang, C.C, West, S.C. 登録日 2023-04-25 公開日 2023-06-21 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (2.2 Å) 主引用文献 Structure and function of the RAD51B-RAD51C-RAD51D-XRCC2 tumour suppressor. Nature, 619, 2023
7UGA	Solution structure of NPSL2 分子名称: NPSL2 RNA (43-MER) 著者 Liu, Y, Keane, S.C. 登録日 2022-03-24 公開日 2022-04-13 最終更新日 2024-05-15 実験手法 SOLUTION NMR, SOLUTION SCATTERING 主引用文献 Solution Structure of NPSL2, A Regulatory Element in the oncomiR-1 RNA. J.Mol.Biol., 434, 2022
6I16	CRYSTAL STRUCTURE OF FASCIN IN COMPLEX WITH COMPOUND 15 分子名称: 6-[(3,4-dichlorophenyl)methyl]-~{N}-(1-methylpyrazol-4-yl)-5-oxidanylidene-1,6-naphthyridine-8-carboxamide, ACETATE ION, Fascin 著者 Schuettelkopf, A.W. 登録日 2018-10-27 公開日 2019-02-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents. Bioorg.Med.Chem.Lett., 29, 2019
8BCM	Structure of Synechococcus elongatus PCC 7942 Rubisco recombinantly expressed from E.coli 分子名称: Ribulose 1,5-bisphosphate carboxylase small subunit, Ribulose bisphosphate carboxylase large chain 著者 Ni, T, Sun, Y, Liu, L.N, Zhang, P. 登録日 2022-10-17 公開日 2023-11-01 実験手法 ELECTRON MICROSCOPY (2.15 Å) 主引用文献 Structure of Rubisco To Be Published
8S9P	1:1:1 agrin/LRP4/MuSK complex 分子名称: Agrin, Low-density lipoprotein receptor-related protein 4, Muscle, ... 著者 Xie, T, Xu, G.J, Liu, Y, Quade, B, Lin, W.C, Bai, X.C. 登録日 2023-03-29 公開日 2023-05-17 最終更新日 2023-06-14 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural insights into the assembly of the agrin/LRP4/MuSK signaling complex. Proc.Natl.Acad.Sci.USA, 120, 2023
5KHO	Rasip1 RA domain in complex with Rap1B 分子名称: GLYCEROL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Gingras, A.R. 登録日 2016-06-15 公開日 2016-10-19 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 Structural Basis of Dimeric Rasip1 RA Domain Recognition of the Ras Subfamily of GTP-Binding Proteins. Structure, 24, 2016
8C9M	HERV-K Gag immature lattice 分子名称: Gag protein 著者 Krebs, A.-S, Liu, H.-F, Zhou, Y, Rey, J.S, Levintov, L, Perilla, J.R, Bartesaghi, A, Zhang, P. 登録日 2023-01-23 公開日 2023-02-01 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Molecular architecture and conservation of an immature human endogenous retrovirus. Biorxiv, 2023
4U90	GephE in complex with PEG crosslinked GABA receptor alpha3 subunit derived dimeric peptide 分子名称: 1,1'-[ethane-1,2-diylbis(oxyethane-2,1-diyl)]bis(1H-pyrrole-2,5-dione), 1,4-BUTANEDIOL, Gamma-aminobutyric acid receptor subunit alpha-3, ... 著者 Kasaragod, V.B, Maric, H.M, Schindelin, H. 登録日 2014-08-05 公開日 2014-12-10 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Design and Synthesis of High-Affinity Dimeric Inhibitors Targeting the Interactions between Gephyrin and Inhibitory Neurotransmitter Receptors. Angew.Chem.Int.Ed.Engl., 54, 2015
4UJA	Protein Kinase A in complex with an Inhibitor 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 7-{(3S,4R)-4-[(5-bromothiophen-2-yl)carbonyl]pyrrolidin-3-yl}quinazolin-4(3H)-one, BROMIDE ION, ... 著者 Alam, K.A, Engh, R.A. 登録日 2015-04-09 公開日 2016-04-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Addressing the Glycine-Rich Loop of Protein Kinases by a Multi-Facetted Interaction Network: Inhibition of Pka and a Pkb Mimic. Chemistry, 22, 2016
4UJ2	Protein Kinase A in complex with an Inhibitor 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 7-[(3S,4R)-4-(3-iodanylphenyl)carbonylpyrrolidin-3-yl]-3H-quinazolin-4-one, CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA, ... 著者 Alam, K.A, Engh, R.A. 登録日 2015-04-07 公開日 2016-04-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.019 Å) 主引用文献 Addressing the Glycine-Rich Loop of Protein Kinases by a Multi-Facetted Interaction Network: Inhibition of Pka and a Pkb Mimic. Chemistry, 22, 2016
4UJB	Protein Kinase A in complex with an Inhibitor 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 7-[(3S,4R)-4-(3-fluorophenyl)carbonylpyrrolidin-3-yl]-3H-quinazolin-4-one, CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA, ... 著者 Alam, K.A, Engh, R.A. 登録日 2015-04-09 公開日 2016-04-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.949 Å) 主引用文献 Addressing the Glycine-Rich Loop of Protein Kinases by a Multi-Facetted Interaction Network: Inhibition of Pka and a Pkb Mimic. Chemistry, 22, 2016
4UJ9	Protein Kinase A in complex with an Inhibitor 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 7-[(3S,4R)-4-[4-(trifluoromethyl)phenyl]carbonylpyrrolidin-3-yl]-3H-quinazolin-4-one, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Alam, K.A, Engh, R.A. 登録日 2015-04-09 公開日 2016-04-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Addressing the Glycine-Rich Loop of Protein Kinases by a Multi-Facetted Interaction Network: Inhibition of Pka and a Pkb Mimic. Chemistry, 22, 2016
4UJ1	Protein Kinase A in complex with an Inhibitor 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 7-[(3S,4R)-4-(3-chlorophenyl)carbonylpyrrolidin-3-yl]-3H-quinazolin-4-one, CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA, ... 著者 Alam, K.A, Engh, R.A. 登録日 2015-04-07 公開日 2016-04-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.768 Å) 主引用文献 Addressing the Glycine-Rich Loop of Protein Kinases by a Multi-Facetted Interaction Network: Inhibition of Pka and a Pkb Mimic. Chemistry, 22, 2016
6AJ4	Crystal structure of the DHR-2 domain of DOCK7 in complex with Cdc42 分子名称: Cell division control protein 42 homolog, Dedicator of cytokinesis protein 7 著者 Kukimoto-Niino, M, Shirouzu, M. 登録日 2018-08-27 公開日 2019-03-20 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.256 Å) 主引用文献 Structural Basis for the Dual Substrate Specificity of DOCK7 Guanine Nucleotide Exchange Factor. Structure, 27, 2019
6AJL	DOCK7 mutant I1836Y complexed with Cdc42 分子名称: Cell division control protein 42 homolog, Dedicator of cytokinesis protein 7 著者 Kukimoto-Niino, M, Shirouzu, M. 登録日 2018-08-28 公開日 2019-03-20 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.23 Å) 主引用文献 Structural Basis for the Dual Substrate Specificity of DOCK7 Guanine Nucleotide Exchange Factor. Structure, 27, 2019
4V6C	Crystal structure of the E. coli 70S ribosome in an intermediate state of ratcheting 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Zhang, W, Dunkle, J.A, Cate, J.H.D. 登録日 2009-06-27 公開日 2014-07-09 最終更新日 2014-12-10 実験手法 X-RAY DIFFRACTION (3.19 Å) 主引用文献 Structures of the ribosome in intermediate States of ratcheting. Science, 325, 2009
4WB7	Crystal structure of a chimeric fusion of human DnaJ (Hsp40) and cAMP-dependent protein kinase A (catalytic alpha subunit) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DnaJ homolog subfamily B member 1,cAMP-dependent protein kinase catalytic subunit alpha, PKI (5-24), ... 著者 Cheung, J, Ginter, C, Cassidy, M, Franklin, M.C, Rudolph, M.J, Hendrickson, W.A. 登録日 2014-09-02 公開日 2015-01-21 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural insights into mis-regulation of protein kinase A in human tumors. Proc.Natl.Acad.Sci.USA, 112, 2015
4V9D	Structures of the bacterial ribosome in classical and hybrid states of tRNA binding 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Dunkle, J.A, Wang, L, Feldman, M.B, Pulk, A, Chen, V.B, Kapral, G.J, Noeske, J, Richardson, J.S, Blanchard, S.C, Cate, J.H.D. 登録日 2012-07-31 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structures of the bacterial ribosome in classical and hybrid states of tRNA binding. Science, 332, 2011
4WB8	Crystal structure of human cAMP-dependent protein kinase A (catalytic alpha subunit), exon 1 deletion 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Cheung, J, Ginter, C, Cassidy, M, Franklin, M.C, Rudolph, M.J, Hendrickson, W.A. 登録日 2014-09-02 公開日 2015-01-21 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structural insights into mis-regulation of protein kinase A in human tumors. Proc.Natl.Acad.Sci.USA, 112, 2015
4WBB	Single Turnover Autophosphorylation Cycle of the PKA RIIb Holoenzyme 分子名称: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Zhang, P, Knape, M.J, Ahuja, L.G, Keshwani, M.M, King, C.C, Sastri, M, Herberg, F.W, Taylor, S.S. 登録日 2014-09-02 公開日 2015-05-20 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Single Turnover Autophosphorylation Cycle of the PKA RII beta Holoenzyme. Plos Biol., 13, 2015

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