PDB: 5653 件ウェブページステータス検索Chemie searchBIRD

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1UNW	Structure Based Engineering of Internal Molecular Surfaces Of Four Helix Bundles 分子名称: GENERAL CONTROL PROTEIN GCN4 著者 Yadav, M.K, Redman, J.E, Alvarez-Gutierrez, J.M, Zhang, Y, Stout, C.D, Ghadiri, M.R. 登録日 2003-09-15 公開日 2004-10-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure-Based Engineering of Internal Cavities in Coiled-Coil Peptides Biochemistry, 44, 2005
3MEN	Crystal structure of acetylpolyamine aminohydrolase from Burkholderia pseudomallei, iodide soak 分子名称: Acetylpolyamine aminohydrolase, IODIDE ION, POTASSIUM ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-03-31 公開日 2010-04-21 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 SAD phasing using iodide ions in a high-throughput structural genomics environment. J Struct Funct Genomics, 12, 2011
1CG3	STRUCTURE OF THE MUTANT (R143L) OF ADENYLOSUCCINATE SYNTHETASE FROM E. COLI COMPLEXED WITH HADACIDIN, GDP, 6-PHOSPHORYL-IMP, AND MG2+ 分子名称: 6-O-PHOSPHORYL INOSINE MONOPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, HADACIDIN, ... 著者 Choe, J.Y, Poland, B.W, Fromm, H, Honzatko, R. 登録日 1999-03-26 公開日 1999-06-17 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Mechanistic implications from crystalline complexes of wild-type and mutant adenylosuccinate synthetases from Escherichia coli. Biochemistry, 38, 1999
3NPU	Optimization of the in silico designed Kemp eliminase KE70 by computational design and directed evolution 分子名称: deoxyribose phosphate aldolase 著者 Khersonsky, O, Rothlisberge, D, Wollacott, A.M, Dym, O, Baker, D, Tawfik, D.S, Israel Structural Proteomics Center (ISPC) 登録日 2010-06-29 公開日 2011-02-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Optimization of the in-silico-designed kemp eliminase KE70 by computational design and directed evolution J.Mol.Biol., 407, 2011
3NPW	In silico designed of an improved Kemp eliminase KE70 mutant by computational design and directed evolution 分子名称: deoxyribose phosphate aldolase 著者 Khersonsky, O, Rothlisberge, D, Wollacott, A.M, Dym, O, Baker, D, Tawfik, D.S, Israel Structural Proteomics Center (ISPC) 登録日 2010-06-29 公開日 2011-02-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Optimization of the in-silico-designed kemp eliminase KE70 by computational design and directed evolution J.Mol.Biol., 407, 2011
3I1C	Crystal Structure of a Novel Engineered Diels-Alderase: DA_20_00_A74I 分子名称: Diisopropyl-fluorophosphatase, GLYCEROL 著者 Lambert, A.R, Stoddard, B.L. 登録日 2009-06-26 公開日 2009-08-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Computational design of an enzyme catalyst for a stereoselective bimolecular Diels-Alder reaction. Science, 329, 2010
3O3Q	Crystal structure of "L44F/M67I/L73V/A103G/deletion 104-106/F108Y/V109L/L111I/C117V/R119G/deletion 120-122" mutant form of Human acidic fibroblast growth factor 分子名称: GLYCEROL, Heparin-binding growth factor 1 著者 Lee, J, Blaber, M. 登録日 2010-07-25 公開日 2011-02-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 A polypeptide "building block"top-down symmetric deconstruction". J.Mol.Biol., 407, 2011
3Q24	X-ray crystal structure of the N4 mini-VRNAP and P2_7a promoter transcription initiation complex with pppGpG and pyrophosphate: product complex 分子名称: DIHYDROGENPHOSPHATE ION, DNA (5'-D(*TP*GP*CP*CP*TP*CP*CP*CP*AP*GP*GP*CP*AP*TP*CP*CP*AP*AP*AP*AP*GP*AP*AP*GP*CP*GP*GP*AP*GP*CP*TP*TP*CP*TP*TP*C)-3'), GUANOSINE-5'-MONOPHOSPHATE, ... 著者 Gleghorn, M.L, Murakami, K.S. 登録日 2010-12-19 公開日 2011-02-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 X-ray crystal structures elucidate the nucleotidyl transfer reaction of transcript initiation using two nucleotides. Proc.Natl.Acad.Sci.USA, 108, 2011
3Q23	X-ray crystal structure of the N4 mini-VRNAP and P2_7a promoter transcription initiation complex with GMPCPP and Manganese: sustrate complex II 分子名称: DIHYDROGENPHOSPHATE ION, DNA (5'-D(*TP*GP*CP*CP*TP*CP*CP*CP*AP*GP*GP*CP*AP*TP*CP*CP*AP*AP*AP*AP*GP*AP*AP*GP*CP*GP*GP*AP*GP*CP*TP*TP*CP*TP*TP*C)-3'), MANGANESE (II) ION, ... 著者 Gleghorn, M.L, Murakami, K.S. 登録日 2010-12-19 公開日 2011-02-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 X-ray crystal structures elucidate the nucleotidyl transfer reaction of transcript initiation using two nucleotides. Proc.Natl.Acad.Sci.USA, 108, 2011
3PI5	Crystal Structure of Human Beta Secretase in Complex with BFG356 分子名称: (3S,4S,5R)-3-(3-bromo-4-hydroxybenzyl)-5-[(3-cyclopropylbenzyl)amino]tetrahydro-2H-thiopyran-4-ol 1,1-dioxide, Beta-secretase 1 著者 Rondeau, J.M. 登録日 2010-11-05 公開日 2011-03-23 最終更新日 2017-03-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure based design, synthesis and SAR of cyclic hydroxyethylamine (HEA) BACE-1 inhibitors. Bioorg.Med.Chem.Lett., 21, 2011
3Q36	Crystal structure of the 4Fe-4S cluster domain of human DNA primase large subunit 分子名称: DNA primase large subunit, FE (III) ION, IRON/SULFUR CLUSTER 著者 Agarkar, V.B, Babayeva, N.D, Tahirov, T.H. 登録日 2010-12-21 公開日 2011-04-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of the C-terminal domain of human DNA primase large subunit: Implications for the mechanism of the primase - polymerase alpha switch. Cell Cycle, 10, 2011
1AJZ	STRUCTURE OF DIHYDROPTEROATE PYROPHOSPHORYLASE 分子名称: DIHYDROPTEROATE SYNTHASE, SULFATE ION 著者 Achari, A, Somers, D.O, Champness, J.N, Bryant, P.K, Rosemond, J, Stammers, D.K. 登録日 1997-05-13 公開日 1998-05-13 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of the anti-bacterial sulfonamide drug target dihydropteroate synthase. Nat.Struct.Biol., 4, 1997
1A0M	1.1 ANGSTROM CRYSTAL STRUCTURE OF A-CONOTOXIN [TYR15]-EPI 分子名称: ALPHA-CONOTOXIN [TYR15]-EPI 著者 Hu, S.-H, Loughnan, M, Miller, R, Weeks, C.M, Blessing, R.H, Alewood, P.F, Lewis, R.J, Martin, J.L. 登録日 1997-12-03 公開日 1999-01-13 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 The 1.1 A resolution crystal structure of [Tyr15]EpI, a novel alpha-conotoxin from Conus episcopatus, solved by direct methods. Biochemistry, 37, 1998
3KM3	Crystal structure of eoxycytidine triphosphate deaminase from anaplasma phagocytophilum at 2.1A resolution 分子名称: Deoxycytidine triphosphate deaminase, IODIDE ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2009-11-09 公開日 2009-11-24 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 SAD phasing using iodide ions in a high-throughput structural genomics environment. J.Struct.Funct.Genom., 12, 2011
1AJ0	CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF E. COLI DIHYDROPTEROATE SYNTHASE 分子名称: 2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE, DIHYDROPTEROATE SYNTHASE, SULFANILAMIDE, ... 著者 Achari, A, Somers, D.O, Champness, J.N, Bryant, P.K, Rosemond, J, Stammers, D.K. 登録日 1997-05-14 公開日 1998-05-20 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of the anti-bacterial sulfonamide drug target dihydropteroate synthase. Nat.Struct.Biol., 4, 1997
1TD1	Crystal Structure of the Purine Nucleoside Phosphorylase from Schistosoma mansoni in complex with acetate 分子名称: ACETATE ION, purine-nucleoside phosphorylase 著者 Pereira, H.D, Franco, G.R, Cleasby, A, Garratt, R.C. 登録日 2004-05-21 公開日 2005-05-24 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structures for the Potential Drug Target Purine Nucleoside Phosphorylase from Schistosoma mansoni Causal Agent of Schistosomiasis. J.Mol.Biol., 353, 2005
1B6S	STRUCTURE OF N5-CARBOXYAMINOIMIDAZOLE RIBONUCLEOTIDE SYNTHETASE 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (N5-CARBOXYAMINOIMIDAZOLE RIBONUCLEOTIDE SYNTHETASE) 著者 Thoden, J.B, Kappock, T.J, Stubbe, J, Holden, H.M. 登録日 1999-01-18 公開日 1999-11-30 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Three-dimensional structure of N5-carboxyaminoimidazole ribonucleotide synthetase: a member of the ATP grasp protein superfamily. Biochemistry, 38, 1999
3NBK	Phosphopantetheine Adenylyltransferase from Mycobacterium tuberculosis in complex with 4'-phosphopantetheine 分子名称: 4'-PHOSPHOPANTETHEINE, NICKEL (II) ION, Phosphopantetheine adenylyltransferase 著者 Wubben, T.J, Mesecar, A.D. 登録日 2010-06-03 公開日 2010-09-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Kinetic, thermodynamic, and structural insight into the mechanism of phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis. J.Mol.Biol., 404, 2010
1UO4	Structure Based Engineering of Internal Molecular Surfaces Of Four Helix Bundles 分子名称: CHLORIDE ION, GENERAL CONTROL PROTEIN GCN4, iodobenzene 著者 Yadav, M.K, Redman, J.E, Alvarez-Gutierrez, J.M, Zhang, Y, Stout, C.D, Ghadiri, M.R. 登録日 2003-09-15 公開日 2004-10-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure-Based Engineering of Internal Cavities in Coiled-Coil Peptides Biochemistry, 44, 2005
3PT9	Crystal structure of mouse DNMT1(731-1602) in the free state 分子名称: DNA (cytosine-5)-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION 著者 Song, J, Patel, D.J. 登録日 2010-12-02 公開日 2010-12-29 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation. Science, 331, 2011
3Q2D	Optimization of the in silico designed Kemp eliminase KE70 by computational design and directed evolution 分子名称: 5-nitro-1H-benzotriazole, Deoxyribose phosphate aldolase 著者 Khersonsky, O, Rothlisberge, D, Wollacott, A.M, Murphy, P, Dym, O, Albeck, S, Kiss, G, Houk, K.N, Baker, D, Tawfik, D.S, Israel Structural Proteomics Center (ISPC) 登録日 2010-12-20 公開日 2011-02-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Optimization of the in-silico-designed kemp eliminase KE70 by computational design and directed evolution J.Mol.Biol., 407, 2011
3Q22	X-ray crystal structure of the N4 mini-VRNAP and P2_7a promoter transcription initiation complex with GTP and Magnesium: substrate complex I 分子名称: DIHYDROGENPHOSPHATE ION, DNA (5'-D(*TP*GP*CP*CP*TP*CP*CP*CP*AP*GP*GP*CP*AP*TP*CP*CP*AP*AP*AP*AP*GP*AP*AP*GP*CP*GP*GP*AP*GP*CP*TP*TP*CP*TP*TP*C)-3'), GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Gleghorn, M.L, Murakami, K.S. 登録日 2010-12-19 公開日 2011-02-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 X-ray crystal structures elucidate the nucleotidyl transfer reaction of transcript initiation using two nucleotides. Proc.Natl.Acad.Sci.USA, 108, 2011
3NBA	Phosphopantetheine Adenylyltranferase from Mycobacterium tuberculosis in complex with adenosine-5'-[(alpha,beta)-methyleno]triphosphate (AMPCPP) 分子名称: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MAGNESIUM ION, Phosphopantetheine adenylyltransferase 著者 Wubben, T.J, Mesecar, A.D. 登録日 2010-06-03 公開日 2010-09-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.68 Å) 主引用文献 Kinetic, thermodynamic, and structural insight into the mechanism of phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis. J.Mol.Biol., 404, 2010
1DGM	CRYSTAL STRUCTURE OF ADENOSINE KINASE FROM TOXOPLASMA GONDII 分子名称: ACETIC ACID, ADENOSINE, ADENOSINE KINASE, ... 著者 Cook, W.J, DeLucas, L.J, Chattopadhyay, D. 登録日 1999-11-24 公開日 2000-11-29 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of adenosine kinase from Toxoplasma gondii at 1.8 A resolution. Protein Sci., 9, 2000
1DHN	1.65 ANGSTROM RESOLUTION STRUCTURE OF 7,8-DIHYDRONEOPTERIN ALDOLASE FROM STAPHYLOCOCCUS AUREUS 分子名称: 7,8-DIHYDRONEOPTERIN ALDOLASE 著者 Hennig, M, D'Arcy, A, Hampele, I.C, Page, M.G.P, Oefner, C.H, Dale, G. 登録日 1998-03-31 公開日 1999-04-20 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure and reaction mechanism of 7,8-dihydroneopterin aldolase from Staphylococcus aureus. Nat.Struct.Biol., 5, 1998

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