1CG3
STRUCTURE OF THE MUTANT (R143L) OF ADENYLOSUCCINATE SYNTHETASE FROM E. COLI COMPLEXED WITH HADACIDIN, GDP, 6-PHOSPHORYL-IMP, AND MG2+
Summary for 1CG3
Entry DOI | 10.2210/pdb1cg3/pdb |
Descriptor | PROTEIN (ADENYLOSUCCINATE SYNTHETASE), MAGNESIUM ION, HADACIDIN, ... (6 entities in total) |
Functional Keywords | ligase, gtp-hydrolysing enzymes, purine 2 nucleotide biosynthesis, 6-phosporyl- imp |
Biological source | Escherichia coli K12 |
Cellular location | Cytoplasm: P0A7D4 |
Total number of polymer chains | 1 |
Total formula weight | 48240.33 |
Authors | Choe, J.Y.,Poland, B.W.,Fromm, H.,Honzatko, R. (deposition date: 1999-03-26, release date: 1999-06-17, Last modification date: 2023-08-09) |
Primary citation | Choe, J.Y.,Poland, B.W.,Fromm, H.J.,Honzatko, R.B. Mechanistic implications from crystalline complexes of wild-type and mutant adenylosuccinate synthetases from Escherichia coli. Biochemistry, 38:6953-6961, 1999 Cited by PubMed: 10346917DOI: 10.1021/bi990159s PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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