1CG3
STRUCTURE OF THE MUTANT (R143L) OF ADENYLOSUCCINATE SYNTHETASE FROM E. COLI COMPLEXED WITH HADACIDIN, GDP, 6-PHOSPHORYL-IMP, AND MG2+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PROTEIN (ADENYLOSUCCINATE SYNTHETASE) | polymer | 431 | 47225.6 | 1 | UniProt (P0A7D4) Pfam (PF00709) | Escherichia coli K12 | AMPSASE |
| 2 | B (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | C (A) | HADACIDIN | non-polymer | 119.1 | 1 | Chemie (HDA) | |||
| 4 | D (A) | 6-O-PHOSPHORYL INOSINE MONOPHOSPHATE | non-polymer | 428.2 | 1 | Chemie (IMO) | |||
| 5 | E (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 6 | F (A) | water | water | 18.0 | 247 | Chemie (HOH) |
Sequence modifications
A: 1 - 431 (UniProt: P0A7D4)
| PDB | External Database | Details |
|---|---|---|
| Leu 143 | Arg 143 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 47225.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1014.8 | |
| All* | Total formula weight | 48240.3 |
