PDB: 1139 件ウェブページステータス検索Chemie searchBIRD

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6HXK	Structure of the citryl-CoA lyase core module of human ATP citrate lyase in complex with citrate 分子名称: 1,2-ETHANEDIOL, ATP-citrate synthase, CITRATE ANION, ... 著者 Verstraete, K, Verschueren, K. 登録日 2018-10-17 公開日 2019-04-10 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019
6HXM	Structure of the citryl-CoA lyase core module of human ATP citrate lyase in complex with citrate and CoASH in space group C2221 分子名称: ATP-citrate synthase, CITRATE ANION, COENZYME A 著者 Verstraete, K, Verschueren, K. 登録日 2018-10-17 公開日 2019-04-10 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019
6HXL	Structure of the citryl-CoA lyase core module of human ATP citrate lyase in complex with citrate and CoASH (space group P21) 分子名称: 1,2-ETHANEDIOL, ATP-citrate synthase, CITRATE ANION, ... 著者 Verstraete, K, Verschueren, K. 登録日 2018-10-17 公開日 2019-04-10 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019
3EUQ	X-ray structural of a type III pentaketide synthase from Neurospora crassa 分子名称: HEXAETHYLENE GLYCOL, Putative uncharacterized protein 著者 Zhang, H, Brunzelle, J.S, Nair, S.K. 登録日 2008-10-10 公開日 2008-11-11 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Distinct Structural Elements Dictate the Specificity of the Type III Pentaketide Synthase from Neurospora crassa. Chem.Biol., 15, 2008
2WWP	Crystal structure of the human lipocalin-type prostaglandin D synthase 分子名称: CHLORIDE ION, PROSTAGLANDIN-H2 D-ISOMERASE, THIOCYANATE ION 著者 Roos, A.K, Tresaugues, L, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Karlberg, T, Kotyenova, T, Kotzch, A, Kraulis, P, Markova, N, Moche, M, Nielsen, T.K, Nyman, T, Persson, C, Schuler, H, Schutz, P, Siponen, M.I, Svensson, L, Thorsell, A.G, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Wisniewska, M, Nordlund, P, Structural Genomics Consortium (SGC) 登録日 2009-10-26 公開日 2010-01-12 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and Dynamic Insights Into Substrate Binding and Catalysis of Human Lipocalin Prostaglandin D Synthase. J.Lipid Res., 54, 2013
3DSK	Crystal Structure of Arabidopsis thaliana Allene Oxide Synthase variant (F137L) (At-AOS(F137L), Cytochrome P450 74A, CYP74A) Complexed with 12R,13S-Vernolic Acid at 1.55 A Resolution 分子名称: (9Z)-11-[(2R,3S)-3-pentyloxiran-2-yl]undec-9-enoic acid, Cytochrome P450 74A, chloroplast, ... 著者 Lee, D.S, Nioche, P, Raman, C.S. 登録日 2008-07-12 公開日 2008-08-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structural insights into the evolutionary paths of oxylipin biosynthetic enzymes Nature, 455, 2008
2ALM	Crystal structure analysis of a mutant beta-ketoacyl-[acyl carrier protein] synthase II from Streptococcus pneumoniae 分子名称: 3-oxoacyl-(acyl-carrier-protein) synthase II, MAGNESIUM ION 著者 Zhang, Y.M, Hurlbert, J, White, S.W, Rock, C.O. 登録日 2005-08-07 公開日 2005-08-30 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Roles of the active site water, histidine 303, and phenylalanine 396 in the catalytic mechanism of the elongation condensing enzyme of Streptococcus pneumoniae. J.Biol.Chem., 281, 2006
4RYB	Crystal structure of beta-ketoacyl-ACP synthase III (FabH) from Neisseria meningitidis 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 3, GLYCEROL 著者 Nanson, J.D, Forwood, J.K. 登録日 2014-12-14 公開日 2014-12-31 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Crystal structure of beta-ketoacyl-ACP synthase III (FabH) from Neisseria meningitidis to be published
3DSJ	Crystal Structure of Arabidopsis thaliana Allene Oxide Synthase Variant (F137L) (At-AOS(F137L), cytochrome P450 74A, CYP74A) Complexed with 13(S)-HOD at 1.60 A Resolution 分子名称: (9Z,11E,13S)-13-hydroxyoctadeca-9,11-dienoic acid, Cytochrome P450 74A, chloroplast, ... 著者 Lee, D.S, Nioche, P, Raman, C.S. 登録日 2008-07-12 公開日 2008-08-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural insights into the evolutionary paths of oxylipin biosynthetic enzymes Nature, 455, 2008
3DSI	Crystal Structure of Arabidopsis thaliana Allene Oxide Synthase (AOS, cytochrome P450 74A, CYP74A) Complexed with 13(S)-HOT at 1.60 A resolution 分子名称: (9Z,11E,13S,15Z)-13-hydroxyoctadeca-9,11,15-trienoic acid, Cytochrome P450 74A, chloroplast, ... 著者 Lee, D.S, Nioche, P, Raman, C.S. 登録日 2008-07-12 公開日 2008-08-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural insights into the evolutionary paths of oxylipin biosynthetic enzymes Nature, 455, 2008
3EL6	Crystal Structure of the Erythromycin Dehydratase 分子名称: CHLORIDE ION, Erythromycin dehydratase, SULFATE ION 著者 Keatinge-Clay, A.T. 登録日 2008-09-20 公開日 2008-11-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal structure of the erythromycin polyketide synthase dehydratase. J.Mol.Biol., 384, 2008
4MZ0	Structure of a ketosynthase-acyltransferase di-domain from module CurL of the curacin A polyketide synthase 分子名称: CALCIUM ION, CurL 著者 Whicher, J.R, Smaga, S.S, Smith, J.L. 登録日 2013-09-28 公開日 2014-01-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Cyanobacterial polyketide synthase docking domains: a tool for engineering natural product biosynthesis. Chem.Biol., 20, 2013
5SXO	1.35 angstrom resolution crystal structure of beta-ketoacyl-ACP synthase II (FabF) from Listeria monocytogenes 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2 著者 Soares da Costa, T.P, Nanson, J.D, Forwood, J.K. 登録日 2016-08-09 公開日 2016-11-02 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 1.35 angstrom resolution crystal structure of beta-ketoacyl-ACP synthase II (FabF) from Listeria monocytogenes To Be Published
2VR1	Crystal structure of Biotin carboxylase from E. coli in complex with ATP analog, ADPCF2P. 分子名称: BIOTIN CARBOXYLASE, CHLORIDE ION, PHOSPHODIFLUOROMETHYLPHOSPHONIC ACID-ADENYLATE ESTER 著者 Mochalkin, I, Waldrop, G.L. 登録日 2008-03-24 公開日 2008-09-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase. Protein Sci., 17, 2008
2CZU	lipocalin-type prostaglandin D synthase 分子名称: Prostaglandin-H2 D-isomerase 著者 Kumasaka, T, Irikura, D, Ago, H, Aritake, K, Yamamoto, M, Inoue, T, Miyano, M, Urade, Y, Hayaishi, O, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-07-17 公開日 2006-10-03 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis of the catalytic mechanism operating in open-closed conformers of lipocalin type prostaglandin D synthase. J.Biol.Chem., 284, 2009
2CZT	lipocalin-type prostaglandin D synthase 分子名称: Prostaglandin-H2 D-isomerase 著者 Kumasaka, T, Irikura, D, Ago, H, Aritake, K, Yamamoto, M, Inoue, T, Miyano, M, Urade, Y, Hayaishi, O, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-07-17 公開日 2006-10-03 最終更新日 2021-11-10 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis of the catalytic mechanism operating in open-closed conformers of lipocalin type prostaglandin D synthase. J.Biol.Chem., 284, 2009
8G7W	Type I modPKS reducing region 分子名称: GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION, ... 著者 McCullough, T.M, Smith, J.L. 登録日 2023-02-17 公開日 2023-06-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structure of a modular polyketide synthase reducing region. Structure, 31, 2023
4IMN	Crystal structure of wild type human Lipocalin PGDS bound with PEG MME 2000 分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, Lipocalin-type prostaglandin-D synthase 著者 Lim, S.M, Chen, D, Teo, H, Roos, A, Nyman, T, Tresaugues, L, Pervushin, K, Nordlund, P. 登録日 2013-01-03 公開日 2013-03-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Structural and dynamic insights into substrate binding and catalysis of human lipocalin prostaglandin D synthase. J.Lipid Res., 54, 2013
3E60	Crystal structure of 3-oxoacyl-(acyl carrier protein) synthase II from Bartonella henselae 分子名称: 3-oxoacyl-[acyl-carrier-protein ] synthase II, POTASSIUM ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2008-08-14 公開日 2008-08-26 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of 3-oxoacyl-(acyl carrier protein) synthase II from Bartonella henselae To be Published
4E1G	X-ray crystal structure of alpha-linolenic acid bound to the cyclooxygenase channel of cyclooxygenase-2 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Vecchio, A.J, Malkowski, M.G. 登録日 2012-03-06 公開日 2012-04-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Investigating Substrate Promiscuity in Cyclooxygenase-2: THE ROLE OF ARG-120 AND RESIDUES LINING THE HYDROPHOBIC GROOVE. J.Biol.Chem., 287, 2012
7LIW	Local refinement of human ATP citrate lyase E599Q mutant ASH domain 分子名称: (2S)-2-hydroxy-2-[2-oxo-2-(phosphonooxy)ethyl]butanedioic acid, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ... 著者 Wei, X, Marmorstein, R. 登録日 2021-01-28 公開日 2021-05-19 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.85 Å) 主引用文献 Reply to: Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase. Nat.Struct.Mol.Biol., 28, 2021
6OFY	Crystal Structure of Arachidonic Acid bound to V349I murine COX-2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACRYLIC ACID, ARACHIDONIC ACID, ... 著者 Malkowski, M.G. 登録日 2019-04-01 公開日 2020-02-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Arg-513 and Leu-531 Are Key Residues Governing Time-Dependent Inhibition of Cyclooxygenase-2 by Aspirin and Celebrex. Biochemistry, 58, 2019
1DDX	CRYSTAL STRUCTURE OF A MIXTURE OF ARACHIDONIC ACID AND PROSTAGLANDIN BOUND TO THE CYCLOOXYGENASE ACTIVE SITE OF COX-2: PROSTAGLANDIN STRUCTURE 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7-[6-(3-HYDROPEROXY-OCT-1-ENYL)-2,3-DIOXA-BICYCLO[2.2.1]HEPT-5-YL]-HEPT-5-ENOIC ACID, ... 著者 Kiefer, J.R, Pawlitz, J.L, Moreland, K.T, Stegeman, R.A, Gierse, J.K, Stevens, A.M, Goodwin, D.C, Rowlinson, S.W, Marnett, L.J, Stallings, W.C, Kurumbail, R.G. 登録日 1999-11-11 公開日 2000-05-16 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural insights into the stereochemistry of the cyclooxygenase reaction. Nature, 405, 2000
1UB7	The Crystal Analysis of Beta-Keroacyl-[Acyl Carrier Protein] Synthase III (FABH)From Thermus Thermophilus. 分子名称: 3-oxoacyl-[acyl-carrier protein] synthase, GLYCEROL 著者 Inagaki, E, Miyano, M, Tahirov, T.H, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2003-03-31 公開日 2003-04-15 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The Crystal Structure of Beta-Ketoacyl-[Acyl Carrier Protein] Synthase III (Fabh) from Thermus Thermophilus To be Published
4XOX	Structure of beta-ketoacyl-ACP synthase I (FabB) from Vibrio Cholerae 分子名称: 3-oxoacyl-ACP synthase 著者 Hou, J, Grabowski, M, Cymborowski, M, Zheng, H, Cooper, D.R, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2015-01-16 公開日 2015-01-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Structure of beta-ketoacyl-ACP synthase I (FabB) from Vibrio Cholerae to be published

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