2WWP

Crystal structure of the human lipocalin-type prostaglandin D synthase

Summary for 2WWP

• Entry DOI: 10.2210/pdb2wwp/pdb
• Descriptor: PROSTAGLANDIN-H2 D-ISOMERASE, CHLORIDE ION, THIOCYANATE ION, ... (4 entities in total)
• Functional Keywords: cytoplasm, transport, endoplasmic reticulum, fatty acid biosynthesis, golgi apparatus, beta-trace protein, isomerase, lipid synthesis
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 2
• Total formula weight: 39683.36

Authors

Roos, A.K.,Tresaugues, L.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Collins, R.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, A.,Johansson, I.,Kallas, A.,Karlberg, T.,Kotyenova, T.,Kotzch, A.,Kraulis, P.,Markova, N.,Moche, M.,Nielsen, T.K.,Nyman, T.,Persson, C.,Schuler, H.,Schutz, P.,Siponen, M.I.,Svensson, L.,Thorsell, A.G.,Van Den Berg, S.,Wahlberg, E.,Weigelt, J.,Welin, M.,Wisniewska, M.,Nordlund, P.,Structural Genomics Consortium (SGC) (deposition date: 2009-10-26, release date: 2010-01-12, Last modification date: 2023-12-20)

• Primary citation: Lim, S.M.,Chen, D.,Teo, H.,Roos, A.,Jansson, A.E.,Nyman, T.,Tresaugues, L.,Pervushin, K.,Nordlund, P.; Structural and Dynamic Insights Into Substrate Binding and Catalysis of Human Lipocalin Prostaglandin D Synthase.; J.Lipid Res., 54:1630-, 2013; PubMed: 23526831; DOI: 10.1194/JLR.M035410

Experimental method

X-RAY DIFFRACTION (2 Å)