PDB: 45118 件ウェブページステータス検索Chemie searchBIRD

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4NI7	Crystal structure of human interleukin 6 in complex with a modified nucleotide aptamer (SOMAMER SL1025) 分子名称: Interleukin-6, SODIUM ION, SOMAmer SL1025 著者 Davies, D, Edwards, T, Gelinas, A, Jarvis, T, Clifton, M.C. 登録日 2013-11-05 公開日 2014-01-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of interleukin-6 in complex with a modified nucleic Acid ligand. J.Biol.Chem., 289, 2014
4NI9	Crystal structure of human interleukin 6 in complex with a modified nucleotide aptamer (SOMAMER SL1025), FORM 2 分子名称: Interleukin-6, SODIUM ION, SOMAmer SL1025 著者 Davies, D, Edwards, T, Gelinas, A, Jarvis, T, Clifton, M.C. 登録日 2013-11-05 公開日 2014-01-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Crystal structure of interleukin-6 in complex with a modified nucleic Acid ligand. J.Biol.Chem., 289, 2014
4TMX	Translation initiation factor eIF5B (517-858) mutant D533N from C. thermophilum, bound to GTP and sodium 分子名称: 1,2-ETHANEDIOL, ACETIC ACID, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Kuhle, B, Ficner, R. 登録日 2014-06-02 公開日 2014-09-24 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 A monovalent cation acts as structural and catalytic cofactor in translational GTPases. Embo J., 33, 2014
3P8N	Crystal structure of HCV NS3/NS4A protease complexed with BI 201335 分子名称: HCV non-structural protein 4A, HCV serine protease NS3, N-[(cyclopentyloxy)carbonyl]-3-methyl-L-valyl-(4R)-4-[(8-bromo-7-methoxy-2-{2-[(2-methylpropanoyl)amino]-1,3-thiazol-4-yl}quinolin-4-yl)oxy]-N-[(1R,2S)-1-carboxy-2-ethenylcyclopropyl]-L-prolinamide, ... 著者 Lemke, C.T. 登録日 2010-10-14 公開日 2011-01-26 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Combined X-ray, NMR, and kinetic analyses reveal uncommon binding characteristics of the hepatitis C virus NS3-NS4A protease inhibitor BI 201335. J.Biol.Chem., 286, 2011
4MUV	M. loti cyclic-nucleotide binding domain mutant displaying inverted ligand selectivity, cyclic-GMP bound 分子名称: CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated potassium channel mll3241, SODIUM ION 著者 Fonseca, F, Pessoa, J, Morais-Cabral, J.H. 登録日 2013-09-23 公開日 2014-06-25 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Determinants of ligand selectivity in a cyclic nucleotide-regulated potassium channel. J.Gen.Physiol., 144, 2014
4MMA	Crystal structure of LeuBAT (delta13 mutant) in complex with clomipramine 分子名称: 3-(3-CHLORO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE, SODIUM ION, Transporter 著者 Wang, H, Gouaux, E. 登録日 2013-09-08 公開日 2013-10-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structural basis for action by diverse antidepressants on biogenic amine transporters. Nature, 503, 2013
4MPP	Crystal Structure of Benzoylformate Decarboxylase Mutant H281Y/T377P/F397T/A460I 分子名称: 2-{3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-4-METHYL-2-OXO-2,3-DIHYDRO-1,3-THIAZOL-5-YL}ETHYL TRIHYDROGEN DIPHOSPHATE, Benzoylformate decarboxylase, CALCIUM ION, ... 著者 Andrews, F.H, McLeish, M.J. 登録日 2013-09-13 公開日 2015-03-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.501 Å) 主引用文献 A pseudo study of thiamin diphosphate-dependent decarboxylases To be Published
4U1P	Human Fyn-SH2 domain in complex with a synthetic high-affinity phospho-peptide 分子名称: Middle T antigen, POLYETHYLENE GLYCOL (N=34), SODIUM ION, ... 著者 Garcia-Pino, A, Huculeci, R, Lenaerts, T, van Nuland, N.A.J. 登録日 2014-07-16 公開日 2015-07-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Human Fyn-SH2 domain in complex with a synthetic high-affinity phospho-peptide To Be Published
4MM6	Crystal structure of LeuBAT (delta13 mutant) in complex with (S)-duloxetine 分子名称: (3S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine, SODIUM ION, Transporter 著者 Wang, H, Gouaux, E. 登録日 2013-09-08 公開日 2013-10-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural basis for action by diverse antidepressants on biogenic amine transporters. Nature, 503, 2013
4NLN	Structure of human DNA polymerase beta complexed with nicked DNA containing a template 8BrG and incoming CTP 分子名称: 5'-D(*CP*CP*GP*AP*CP*(BGM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... 著者 Koag, M.-C, Min, K, Monzingo, A.F, Lee, S. 登録日 2013-11-14 公開日 2014-01-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.261 Å) 主引用文献 Structural basis for promutagenicity of 8-halogenated Guanine. J.Biol.Chem., 289, 2014
4NLZ	Structure of human DNA polymerase beta complexed with nicked DNA containing a mismatched template 8BrG and incoming GTP 分子名称: 5'-D(*CP*CP*GP*AP*CP*(BGM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*AP*G)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... 著者 Koag, M.-C, Min, K, Monzingo, A.F, Lee, S. 登録日 2013-11-14 公開日 2014-01-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.683 Å) 主引用文献 Structural basis for promutagenicity of 8-halogenated Guanine. J.Biol.Chem., 289, 2014
4NTL	Crystal structure of a lipoprotein, YaeC family (EF3198) from Enterococcus faecalis V583 at 1.80 A resolution 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Lipoprotein, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2013-12-02 公開日 2013-12-11 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.799 Å) 主引用文献 Crystal structure of a lipoprotein, YaeC family (EF3198) from Enterococcus faecalis V583 at 1.80 A resolution To be published
1XOG	N9 Tern Influenza neuraminidase complexed with a 2,5-Disubstituted tetrahydrofuran-5-carboxylic acid 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-[1-(ACETYLAMINO)-3-METHYLBUTYL]-2,5-ANHYDRO-3,4-DIDEOXY-4-(METHOXYCARBONYL)PENTONIC ACID, Neuraminidase, ... 著者 Wang, G.T, Wang, S, Gentles, R, Sowin, T, Maring, C.J, Kempf, D.J, Kati, W.M, Stoll, V, Stewart, K.D, Laver, G. 登録日 2004-10-06 公開日 2005-01-11 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Design, synthesis, and structural analysis of inhibitors of influenza neuraminidase containing a 2,3-disubstituted tetrahydrofuran-5-carboxylic acid core. Bioorg.Med.Chem.Lett., 15, 2005
3OGU	DNA Polymerase beta mutant 5P20 complexed with 6bp of DNA 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-D(*CP*AP*TP*CP*TP*G)-3', 5'-D(P*CP*AP*GP*AP*TP*G)-3', ... 著者 Marx, A, Diederichs, K, Bergen, K. 登録日 2010-08-17 公開日 2010-11-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.845 Å) 主引用文献 Human DNA polymerase beta mutations allowing efficient abasic site bypass. J.Biol.Chem., 286, 2011
4NTP	Crystal structure of macrocycles containing A 17-23 (LV(PHI)FAED) and A 30-36 (AII(SAR)L(ORN)V) 分子名称: CHLORIDE ION, Cyclic hexadecapeptide (ORN)LV(PHI)FAED(ORN)AII(SAR)L(ORN)V, SODIUM ION 著者 Nowick, J.S, Spencer, R.K, Li, H. 登録日 2013-12-02 公開日 2014-04-02 最終更新日 2020-10-21 実験手法 X-RAY DIFFRACTION (1.987 Å) 主引用文献 X-ray crystallographic structures of trimers and higher-order oligomeric assemblies of a peptide derived from A beta (17-36). J.Am.Chem.Soc., 136, 2014
4O0H	Crystal structure of human L-asparaginase protein with covalently linked substrate L-asparagine 分子名称: BETA-L-ASPARTIC ACID, Isoaspartyl peptidase/L-asparaginase, SODIUM ION 著者 Nomme, J, Lavie, A. 登録日 2013-12-13 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Elucidation of the Specific Function of the Conserved Threonine Triad Responsible for Human l-Asparaginase Autocleavage and Substrate Hydrolysis. J.Mol.Biol., 426, 2014
1VCJ	Influenza B virus neuraminidase complexed with 1-(4-Carboxy-2-(3-pentylamino)phenyl)-5-aminomethyl-5-hydroxymethyl-pyrrolidin-2-one 分子名称: 4-[(2R)-2-(AMINOMETHYL)-2-(HYDROXYMETHYL)-5-OXOPYRROLIDIN-1-YL]-3-[(1-ETHYLPROPYL)AMINO]BENZOIC ACID, NEURAMINIDASE 著者 Lommer, B.S, Ali, S.M, Bajpai, S.N, Brouillette, W.J, Air, G.M, Luo, M. 登録日 2004-03-09 公開日 2004-03-23 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A benzoic acid inhibitor induces a novel conformational change in the active site of Influenza B virus neuraminidase. Acta Crystallogr.,Sect.D, 60, 2004
4NXZ	DNA polymerase beta with O6mG in the template base opposite to incoming non-hydrolyzable TTP with manganese in the active site 分子名称: 5'-D(*CP*CP*GP*AP*CP*(6OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... 著者 Koag, M.-C, Min, K, Monzingo, A.F, Lee, S. 登録日 2013-12-09 公開日 2014-04-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.557 Å) 主引用文献 Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta. J.Am.Chem.Soc., 136, 2014
4NY8	DNA polymerase beta with O6mG in the template base opposite to incoming non-hydrolyzable CTP with manganese in the active site 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, 5'-D(*CP*CP*GP*AP*CP*(6OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3', ... 著者 Koag, M.-C, Min, K, Monzingo, A.F, Lee, S. 登録日 2013-12-10 公開日 2014-04-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.246 Å) 主引用文献 Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta. J.Am.Chem.Soc., 136, 2014
4NT8	Formyl-methionine-alanine complex structure of peptide deformylase from Xanthomoonas oryzae pv. oryzae 分子名称: ACETATE ION, ALANINE, CADMIUM ION, ... 著者 Ngo, H.P.T, Kim, J.K, Kang, L.W. 登録日 2013-12-02 公開日 2014-12-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Substrate complex structure of Xoo1075, a peptide deformylase, from Xanthomonas oryzae pv. oryzae To be Published
4O0D	Crystal structure of the human L-asparaginase protein T168S mutant 分子名称: GLYCINE, Isoaspartyl peptidase/L-asparaginase, SODIUM ION 著者 Nomme, J, Lavie, A. 登録日 2013-12-13 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Elucidation of the Specific Function of the Conserved Threonine Triad Responsible for Human l-Asparaginase Autocleavage and Substrate Hydrolysis. J.Mol.Biol., 426, 2014
4O0I	Crystal structure of fragment DNA polymerase I from Bacillus stearothermophilus with 2'-MeSe-arabino-guanosine derivatized DNA 分子名称: 5'-D(*C*(1TW)P*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', DNA polymerase I, GLYCEROL, ... 著者 Jiang, S, Gan, J, Sun, H, Huang, Z. 登録日 2013-12-13 公開日 2014-12-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.203 Å) 主引用文献 Crystal structure of fragment DNA polymerase I from Bacillus stearothermophilus with 2'-MeSe-arabino-guanosine derivatized DNA TO BE PUBLISHED
3PEC	Siderocalin Recognitin of Carboxymycobactins: Interference by the immune system in intracellular iron acquisition by Mycobacteria tuberculosis 分子名称: 9-{hydroxy[(5S,6R)-6-hydroxy-6-{[(1S)-3-{[(3S)-1-hydroxy-2-oxoazepan-3-yl]amino}-1-methyl-3-oxopropyl]oxy}-5-({[(4S)-2-(2-hydroxyphenyl)-4,5-dihydro-1,3-oxazol-4-yl]carbonyl}amino)hexyl]amino}-9-oxononanoic acid, FE (III) ION, GLYCEROL, ... 著者 Clifton, M.C. 登録日 2010-10-25 公開日 2011-10-05 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Siderocalin Recognitin of Carboxymycobactins: Interference by the immune system in intracellular iron acquisition by Mycobacteria tuberculosis To be Published
4O0E	Crystal structure of the human L-asparaginase protein T186V mutant 分子名称: Isoaspartyl peptidase/L-asparaginase, SODIUM ION 著者 Nomme, J, Lavie, A. 登録日 2013-12-13 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Elucidation of the Specific Function of the Conserved Threonine Triad Responsible for Human l-Asparaginase Autocleavage and Substrate Hydrolysis. J.Mol.Biol., 426, 2014
4O47	Crystal structure of uncleaved guinea pig L-asparaginase type III 分子名称: SODIUM ION, Uncharacterized protein 著者 Schalk, A.M, Lavie, A. 登録日 2013-12-18 公開日 2014-04-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and Kinetic Characterization of Guinea Pig l-Asparaginase Type III. Biochemistry, 53, 2014

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