PDB: 222624 件ウェブページステータス検索Chemie searchBIRD

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1E90	Structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin and staurosporine 分子名称: 3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT 著者 Walker, E.H, Pacold, M.E, Perisic, O, Stephens, L, Hawkins, P.T, Wymann, M.P, Williams, R.L. 登録日 2000-10-03 公開日 2000-11-17 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural Determinations of Phosphoinositide 3-Kinase Inhibition by Wortmannin, Ly294002, Quercetin, Myricetin and Staurosporine Mol.Cell, 6, 2000
1E91	Structure of the complex of the Mad1-Sin3B interaction domains 分子名称: MAD PROTEIN (MAX DIMERIZER), PAIRED AMPHIPATHIC HELIX PROTEIN SIN3B 著者 Spronk, C.A.E.M, Tessari, M, Kaan, A.M, Jansen, J.F.A, Vermeulen, M, Stunnenberg, H.G, Vuister, G.W. 登録日 2000-10-04 公開日 2000-11-20 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The MAD1-Sin3B Interaction Involves a Novel Helical Fold Nat.Struct.Biol., 7, 2000
1E92	Pteridine reductase 1 from Leishmania major complexed with NADP+ and dihydrobiopterin 分子名称: 1,2-ETHANEDIOL, 7,8-DIHYDROBIOPTERIN, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Schuettelkopf, A.W, Hunter, W.N. 登録日 2000-10-04 公開日 2001-10-05 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Pteridine Reductase Mechanism Correlates Pterin Metabolism with Drug Resistance in Trypanosomatid Parasites Nat.Struct.Biol., 8, 2001
1E93	High resolution structure and biochemical properties of a recombinant catalase depleted in iron 分子名称: ACETATE ION, CATALASE, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Andreoletti, P, Sainz, G, Jaquinod, M, Gagnon, J, Jouve, H.M. 登録日 2000-10-05 公開日 2000-10-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 High-Resolution Structure and Biochemical Properties of a Recombinant Proteus Mirabilis Catalase Depleted in Iron. Proteins: Struct.,Funct., Genet., 50, 2003
1E94	HslV-HslU from E.coli 分子名称: HEAT SHOCK PROTEIN HSLU, HEAT SHOCK PROTEIN HSLV, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Song, H.K, Hartmann, C, Ravishankar, R, Bochtler, M. 登録日 2000-10-07 公開日 2000-11-17 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Mutational Studies on Hslu and its Docking Mode with Hslv Proc.Natl.Acad.Sci.USA, 97, 2000
1E95	Solution structure of the pseudoknot of SRV-1 RNA, involved in ribosomal frameshifting 分子名称: RNA (5'-(*GP*CP*GP*GP*CP*CP*AP*GP*CP*UP*CP* CP*AP*GP*GP*CP*CP*GP*CP*CP*AP*AP*AP*CP* AP*AP*UP*AP*UP*GP*GP*AP*GP*CP*AP*C)-3') 著者 Michiels, P.J.A, Versleyen, A, Pleij, C.W.A, Hilbers, C.W, Heus, H.A. 登録日 2000-10-09 公開日 2001-08-23 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution Structure of the Pseudoknot of Srv-1 RNA, Involved in Ribosomal Frameshifting J.Mol.Biol., 310, 2001
1E96	Structure of the Rac/p67phox complex 分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, NEUTROPHIL CYTOSOL FACTOR 2 (NCF-2) TPR DOMAIN, ... 著者 Lapouge, K, Smith, S.J.M, Walker, P.A, Gamblin, S.J, Smerdon, S.J, Rittinger, K. 登録日 2000-10-10 公開日 2000-11-17 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of the TPR domain of p67phox in complex with Rac.GTP. Mol.Cell, 6, 2000
1E97	Crystal structure of ketosteroid isomerase from Pseudomonas putida ; triple mutant y16f/y32f/y57f 分子名称: STEROID DELTA-ISOMERASE 著者 Ha, N.-C, Oh, B.-H. 登録日 2000-10-10 公開日 2001-10-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Peudoreversion of the Catalytic Activity of Y14F by the Additional Substitution(S) of Tyrosine with Phenylalanine in the Hydrogen Bond Network of Delta 5-3-Ketosteroid Isomerase from Pseudomonas Putida Biotype B Biochemistry, 40, 2001
1E98	Wild type human thymidylate kinase complexed with AZTMP and ADP 分子名称: 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Ostermann, N, Lavie, A, Padiyar, S, Brundiers, R, Veit, T, Reintein, J, Goody, R.S, Konrad, M, Schlichting, I. 登録日 2000-10-10 公開日 2001-10-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Potentiating Azt Activation: Structures of Wildtype and Mutant Human Thymidylate Kinase Suggest Reasons for the Mutants' Improved Kinetics with the HIV Prodrug Metabolite Aztmp J.Mol.Biol., 304, 2000
1E99	Human thymidylate kinase complexed with AZTMP and ADP 分子名称: 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Ostermann, N, Lavie, A, Padiyar, S, Brundiers, R, Veit, T, Reinstein, J, Goody, R.S, Konrad, M, Schlichting, I. 登録日 2000-10-10 公開日 2001-10-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Potentiating Azt Activation: Structures of Wildtype and Mutant Human Thymidylate Kinase Suggest Reasons for the Mutants' Improved Kinetics with the HIV Prodrug Metabolite Aztmp J.Mol.Biol., 304, 2000
1E9A	Human thymidylate kinase complexed with the bisubstrate inhibitor AZTP5A 分子名称: MAGNESIUM ION, P1-(5'-ADENOSYL)P5-(5'-(3'AZIDO-3'-DEOXYTHYMIDYL))PENTAPHOSPHATE, THYMIDYLATE KINASE 著者 Ostermann, N, Lavie, A, Padiyar, S, Brundiers, R, Veit, T, Reintein, J, Goody, R.S, Konrad, M, Schlichting, I. 登録日 2000-10-10 公開日 2001-10-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Potentiating Azt Activation: Structures of Wildtype and Mutant Human Thymidylate Kinase Suggest Reasons for the Mutants' Improved Kinetics with the HIV Prodrug Metabolite Aztmp J.Mol.Biol., 304, 2000
1E9B	Human thymidylate kinase complexed with AZTMP and APPNP 分子名称: 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Ostermann, N, Lavie, A, Padiyar, S, Brundiers, R, Veit, T, Reintein, J, Goody, R.S, Konrad, M, Schlichting, I. 登録日 2000-10-10 公開日 2001-10-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Potentiating Azt Activation: Structures of Wildtype and Mutant Human Thymidylate Kinase Suggest Reasons for the Mutants' Improved Kinetics with the HIV Prodrug Metabolite Aztmp J.Mol.Biol., 304, 2000
1E9C	Mutant human thymidylate kinase complexed with TMP and APPNP 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Ostermann, N, Lavie, A, Padiyar, S, Brundiers, R, Veit, T, Reintein, J, Goody, R.S, Konrad, M, Schlichting, I. 登録日 2000-10-10 公開日 2001-10-11 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Potentiating Azt Activation: Structures of Wildtype and Mutant Human Thymidylate Kinase Suggest Reasons for the Mutants' Improved Kinetics with the HIV Prodrug Metabolite Aztmp J.Mol.Biol., 304, 2000
1E9D	Mutant human thymidylate kinase (F105Y) complexed with AZTMP and ADP 分子名称: 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Ostermann, N, Lavie, A, Padiyar, S, Brundiers, R, Veit, T, Reintein, J, Goody, R.S, Konrad, M, Schlichting, I. 登録日 2000-10-10 公開日 2001-10-11 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Potentiating Azt Activation: Structures of Wildtype and Mutant Human Thymidylate Kinase Suggest Reasons for the Mutants' Improved Kinetics with the HIV Prodrug Metabolite Aztmp J.Mol.Biol., 304, 2000
1E9E	Mutant human thymidylate kinase (F105Y) complexed with dTMP and ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, THYMIDINE-5'-PHOSPHATE, ... 著者 Ostermann, N, Lavie, A, Padiyar, S, Brundiers, R, Veit, T, Reintein, J, Goody, R.S, Konrad, M, Schlichting, I. 登録日 2000-10-11 公開日 2001-10-11 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Potentiating Azt Activation: Structures of Wildtype and Mutant Human Thymidylate Kinase Suggest Reasons for the Mutants' Improved Kinetics with the HIV Prodrug Metabolite Aztmp J.Mol.Biol., 304, 2000
1E9F	Mutant human thymidylate kinase complexed with TMP and ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, THYMIDINE-5'-PHOSPHATE, ... 著者 Ostermann, N, Lavie, A, Padiyar, S, Brundiers, R, Veit, T, Reinstein, J, Goody, R.S, Konrad, M, Schlichting, I. 登録日 2000-10-11 公開日 2001-10-11 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Potentiating Azt Activation: Structures of Wildtype and Mutant Human Thymidylate Kinase Suggest Reasons for the Mutants' Improved Kinetics with the HIV Prodrug Metabolite Aztmp J.Mol.Biol., 304, 2000
1E9G	STRUCTURE OF INORGANIC PYROPHOSPHATASE 分子名称: INORGANIC PYROPHOSPHATASE, MANGANESE (II) ION, PHOSPHATE ION 著者 Heikinheimo, P, Tuominen, V, Ahonen, A.-K, Teplyakov, A, Cooperman, B.S, Baykov, A.A, Lahti, R, Goldman, A. 登録日 2000-10-12 公開日 2001-03-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Toward a Quantum-Mechanical Description of Metal-Assisted Phosphoryl Transfer in Pyrophosphatase Proc.Natl.Acad.Sci.USA, 98, 2001
1E9H	Thr 160 phosphorylated CDK2 - Human cyclin A3 complex with the inhibitor indirubin-5-sulphonate bound 分子名称: 2',3-DIOXO-1,1',2',3-TETRAHYDRO-2,3'-BIINDOLE-5'-SULFONIC ACID, CELL DIVISION PROTEIN KINASE 2, CYCLIN A3 著者 Davies, T.G, Tunnah, P, Noble, M.E.M, Endicott, J.A. 登録日 2000-10-16 公開日 2001-10-11 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Inhibitor Binding to Active and Inactive Cdk2: The Crystal Structure of Cdk2-Cyclin A/Indirubin-5-Sulphonate Structure, 9, 2001
1E9I	Enolase from E.coli 分子名称: ENOLASE, MAGNESIUM ION, SULFATE ION 著者 Kuhnel, K, Carpousis, A.J, Luisi, B. 登録日 2000-10-17 公開日 2001-03-15 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Crystal Structure of the Escherichia Coli RNA Degradosome Component Enolase J.Mol.Biol., 313, 2001
1E9J	SOLUTION STRUCTURE OF THE A-SUBUNIT OF HUMAN CHORIONIC GONADOTROPIN [INCLUDING A SINGLE GLCNAC RESIDUE AT ASN52 AND ASN78] 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHORIONIC GONADOTROPIN 著者 Erbel, P.J.A, Karimi-Nejad, Y, van Kuik, J.A, Boelens, R, Kamerling, J.P, Vliegenthart, J.F.G. 登録日 2000-10-18 公開日 2002-07-25 最終更新日 2020-07-29 実験手法 SOLUTION NMR 主引用文献 Effects of the N-linked glycans on the 3D structure of the free alpha-subunit of human chorionic gonadotropin. Biochemistry, 39, 2000
1E9K	The structure of the RACK1 interaction sites located within the unique N-terminal region of the cAMP-specific phosphodiesterase, PDE4D5. 分子名称: cAMP-specific 3',5'-cyclic phosphodiesterase 4D 著者 Bolger, G.B, Smith, K.J, McCahill, A, Hyde, E.I, Steele, M.R, Houslay, M.D. 登録日 2000-10-20 公開日 2001-10-18 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 1H NMR structural and functional characterisation of a cAMP-specific phosphodiesterase-4D5 (PDE4D5) N-terminal region peptide that disrupts PDE4D5 interaction with the signalling scaffold proteins, beta-arrestin and RACK1. Cell. Signal., 19, 2007
1E9L	The crystal structure of novel mammalian lectin Ym1 suggests a saccharide binding site 分子名称: 2-amino-2-deoxy-beta-D-glucopyranose, YM1 SECRETORY PROTEIN 著者 Hsiao, C.D, Sun, Y.J. 登録日 2000-10-21 公開日 2001-03-01 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The Crystal Structure of a Novel Mammalian Lectin, Ym1, Suggests a Saccharide Binding Site J.Biol.Chem., 276, 2001
1E9M	Ferredoxin VI from Rhodobacter Capsulatus 分子名称: FE2/S2 (INORGANIC) CLUSTER, FERREDOXIN VI 著者 Sainz, G, Armengaud, J, Stojanoff, V, Sanishvili, N, Jouanneau, Y, Larry, S. 登録日 2000-10-24 公開日 2001-04-09 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Crystallization and Preliminary X-Ray Diffraction Analysis of a [2Fe-2S] Ferredoxin (Fdvi) from Rhodobacter Capsulatus Acta Crystallogr.,Sect.D, 57, 2001
1E9N	A second divalent metal ion in the active site of a new crystal form of human apurinic/apyrimidinic endonuclease, Ape1, and its implications for the catalytic mechanism 分子名称: DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE, LEAD (II) ION 著者 Beernink, P.T, Segelke, B.W, Rupp, B. 登録日 2000-10-24 公開日 2001-02-16 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Two Divalent Metal Ions in the Active Site of a New Crystal Form of Human Apurinic/Apyrimidinic Endonuclease, Ape1: Implications for the Catalytic Mechanism J.Mol.Biol., 307, 2001
1E9O	Crystal structure of bovine SOD - 1 of 3 分子名称: COPPER (II) ION, SUPEROXIDE DISMUTASE 著者 Hough, M.A, Samar Hasnain, S. 登録日 2000-10-25 公開日 2000-12-03 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Conformational Variability of the Cu Site in One Subunit of Bovine Cuzn Superoxide Dismutase: The Importance of Mobility in the Glu119-Leu142 Loop Region for Catalytic Function J.Mol.Biol., 304, 2000

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