PDB: 82129 件ウェブページステータス検索Chemie searchBIRD

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8ELE	Co-crystal structure of Chaetomium glucosidase with compound 16 分子名称: (2R,3R,4R,5S)-2-(hydroxymethyl)-1-{[4-({2-nitro-4-[(1R,5S)-3-oxa-8-azabicyclo[3.2.1]octan-8-yl]anilino}methyl)phenyl]methyl}piperidine-3,4,5-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Chaetomium alpha glucosidase, ... 著者 Karade, S.S, Mariuzza, R.A. 登録日 2022-09-23 公開日 2023-02-22 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure-Based Design of Potent Iminosugar Inhibitors of Endoplasmic Reticulum alpha-Glucosidase I with Anti-SARS-CoV-2 Activity. J.Med.Chem., 66, 2023
8EL9	Cryo-EM structure of human catalase 分子名称: Catalase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROTOPORPHYRIN IX CONTAINING FE 著者 Su, C.C. 登録日 2022-09-23 公開日 2023-10-04 実験手法 ELECTRON MICROSCOPY (2.27 Å) 主引用文献 Cryo-EM structure of human catalase To Be Published
8EL8	CryoEM structure of Resistance to Inhibitors of Cholinesterase-8B (Ric-8B) in complex with olfactory G protein alpha olf 分子名称: Guanine nucleotide-binding protein G(olf) subunit alpha, Isoform 1 of Synembryn-B 著者 Papasergi-Scott, M.M, Skiniotis, G. 登録日 2022-09-23 公開日 2023-03-01 最終更新日 2023-05-17 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structures of Ric-8B in complex with G alpha protein folding clients reveal isoform specificity mechanisms. Structure, 31, 2023
8EL7	CryoEM structure of Resistance to Inhibitors of Cholinesterase-8B (Ric-8B) in complex with G alpha s 分子名称: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Isoform 1 of Synembryn-B 著者 Papasergi-Scott, M.M, Skiniotis, G. 登録日 2022-09-23 公開日 2023-03-01 最終更新日 2023-05-17 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structures of Ric-8B in complex with G alpha protein folding clients reveal isoform specificity mechanisms. Structure, 31, 2023
8EL6	Light harvesting phycobiliprotein HaPE555 from the cryptophyte Hemiselmis andersenii CCMP644 with an altered helix hA/hY conformation 分子名称: DiCys-(15,16)-Dihydrobiliverdin, PHYCOERYTHROBILIN, Phycoerythrin alpha-1 subunit, ... 著者 Rathbone, H.W, Michie, K.A, Laos, A.L, Curmi, P.M.G. 登録日 2022-09-23 公開日 2023-10-25 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Molecular dissection of the soluble photosynthetic antenna from the cryptophyte alga Hemiselmis andersenii. Commun Biol, 6, 2023
8EL5	Light harvesting phycobiliprotein HaPE555 from the cryptophyte Hemiselmis andersenii CCMP644 in an alternating tight to loose interface filament 分子名称: DiCys-(15,16)-Dihydrobiliverdin, GLYCEROL, PHYCOERYTHROBILIN, ... 著者 Rathbone, H.W, Michie, K.A, Laos, A.L, Curmi, P.M.G. 登録日 2022-09-23 公開日 2023-10-25 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Molecular dissection of the soluble photosynthetic antenna from the cryptophyte alga Hemiselmis andersenii. Commun Biol, 6, 2023
8EL4	Light harvesting phycobiliprotein HaPE555 from the cryptophyte Hemiselmis andersenii CCMP644 in a tight interface filament 分子名称: DiCys-(15,16)-Dihydrobiliverdin, PHYCOERYTHROBILIN, Phycoerythrin alpha-1 subunit, ... 著者 Rathbone, H.W, Michie, K.A, Laos, A.L, Curmi, P.M.G. 登録日 2022-09-23 公開日 2023-10-25 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Molecular dissection of the soluble photosynthetic antenna from the cryptophyte alga Hemiselmis andersenii. Commun Biol, 6, 2023
8EL3	Light harvesting phycobiliprotein HaPE555 from the cryptophyte Hemiselmis andersenii CCMP644 in a loose interface filament 分子名称: DiCys-(15,16)-Dihydrobiliverdin, PHYCOERYTHROBILIN, Phycoerythrin alpha-1 subunit, ... 著者 Rathbone, H.W, Michie, K.A, Laos, A.L, Curmi, P.M.G. 登録日 2022-09-23 公開日 2023-10-25 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Molecular dissection of the soluble photosynthetic antenna from the cryptophyte alga Hemiselmis andersenii. Commun Biol, 6, 2023
8EL2	SARS-CoV-2 RBD bound to neutralizing antibody Fab ICO-hu23 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab ICO-hu23 Heavy Chain, Fab ICO-hu23 Light Chain, ... 著者 Besaw, J.E, Kuo, A, Morizumi, T, Ernst, O.P. 登録日 2022-09-22 公開日 2023-07-19 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Broadly neutralizing humanized SARS-CoV-2 antibody binds to a conserved epitope on Spike and provides antiviral protection through inhalation-based delivery in non-human primates. Plos Pathog., 19, 2023
8EKZ	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGGAGAAGTAGG) 分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*GP*AP*GP*AP*AP*GP*TP*AP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*TP*AP*CP*TP*TP*CP*TP*CP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... 著者 Terrell, J.R, Poon, G.M.K. 登録日 2022-09-22 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8EKX	Structure of MBP-Mcl-1 in complex with MIK665 分子名称: (2~{R})-2-[5-[3-chloranyl-2-methyl-4-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl]-6-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-yl]oxy-3-[2-[[2-(2-methoxyphenyl)pyrimidin-4-yl]methoxy]phenyl]propanoic acid, Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Judge, R.A, Judd, A.S, Souers, A.J. 登録日 2022-09-22 公開日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Selective MCL-1 inhibitor ABBV-467 is efficacious in tumor models but is associated with cardiac troponin increases in patients. Commun Med (Lond), 3, 2023
8EKV	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGATGTGGG) 分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*TP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*AP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... 著者 Terrell, J.R, Poon, G.M.K. 登録日 2022-09-22 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8EKU	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAATGGAATGGGG) 分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*AP*TP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*AP*TP*TP*TP*AP*T)-3'), Transcription factor PU.1 著者 Terrell, J.R, Poon, G.M.K. 登録日 2022-09-22 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8EKT	CYP51 from Acanthamoeba castellanii in complex with the tetrazole-based IND inhibitor VT-1161(VT1) 分子名称: (R)-2-(2,4-Difluorophenyl)-1,1-difluoro-3-(1H-tetrazol-1-yl)-1-(5-(4-(2,2,2-trifluoroethoxy)phenyl)pyridin-2-yl)propan-2-ol, PROTOPORPHYRIN IX CONTAINING FE, sterol 14a-demethylase 著者 Hargrove, T.Y, Wawrzak, Z, Lepesheva, G.I. 登録日 2022-09-21 公開日 2023-08-02 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Identification of Potent and Selective Inhibitors of Acanthamoeba : Structural Insights into Sterol 14 alpha-Demethylase as a Key Drug Target. J.Med.Chem., 67, 2024
8EKS	rat TRPV2 in nanodiscs in the presence of weak acid at pH 5 分子名称: 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Transient receptor potential cation channel subfamily V member 2 著者 Pumroy, R.A, Moiseenkova-Bell, V.Y. 登録日 2022-09-21 公開日 2023-09-27 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Functional and structural insights into activation of TRPV2 by weak acids. Embo J., 43, 2024
8EKR	Apo rat TRPV2 in nanodiscs, state 3 分子名称: 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Transient receptor potential cation channel subfamily V member 2 著者 Pumroy, R.A, Moiseenkova-Bell, V.Y. 登録日 2022-09-21 公開日 2023-09-27 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Functional and structural insights into activation of TRPV2 by weak acids. Embo J., 43, 2024
8EKQ	Apo rat TRPV2 in nanodiscs, state 2 分子名称: 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Transient receptor potential cation channel subfamily V member 2 著者 Pumroy, R.A, Moiseenkova-Bell, V.Y. 登録日 2022-09-21 公開日 2023-09-27 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Functional and structural insights into activation of TRPV2 by weak acids. Embo J., 43, 2024
8EKP	Apo rat TRPV2 in nanodiscs, state 1 分子名称: 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Transient receptor potential cation channel subfamily V member 2 著者 Pumroy, R.A, Moiseenkova-Bell, V.Y. 登録日 2022-09-21 公開日 2023-09-27 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.75 Å) 主引用文献 Functional and structural insights into activation of TRPV2 by weak acids. Embo J., 43, 2024
8EKN	Co-crystal structure of Chaetomium glucosidase with compound 15 分子名称: (2R,3R,4R,5S)-2-(hydroxymethyl)-1-{[4-({[(5P)-3-methyl-5-(pyridazin-3-yl)phenyl]amino}methyl)phenyl]methyl}piperidine-3,4,5-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Chaetomium alpha glucosidase, ... 著者 Karade, S.S, Mariuzza, R.A. 登録日 2022-09-21 公開日 2023-02-22 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Structure-Based Design of Potent Iminosugar Inhibitors of Endoplasmic Reticulum alpha-Glucosidase I with Anti-SARS-CoV-2 Activity. J.Med.Chem., 66, 2023
8EKJ	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAATGGAAGTGGG) 分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*AP*TP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*AP*TP*TP*TP*AP*T)-3'), Transcription factor PU.1 著者 Terrell, J.R, Poon, G.M.K. 登録日 2022-09-21 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8EKF	X-ray crystal structure of 311R Fab in complex with the PfCSP peptide NPNA-3 分子名称: 311R Heavy Chain, 311R Light Chain, PfCSP peptide NPNA-3 著者 Moskovitz, R, Wilson, I.A. 登録日 2022-09-20 公開日 2022-10-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection. Nat Commun, 14, 2023
8EKD	Cryo-EM map of SARS-CoV-2 Omicron BA.2 spike in complex with 2130-1-0114-112 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab LLNL-199 HC, Fab LLNL-199 LC, ... 著者 Binshtein, E, Crowe, J.E. 登録日 2022-09-20 公開日 2024-02-21 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Computationally restoring the potency of a clinical antibody against Omicron. Nature, 629, 2024
8EKA	Cryo-EM structure of a potent anti-malarial antibody L9 in complex with Plasmodium falciparum circumsporozoite protein (PfCSP)(class 2) 分子名称: Circumsporozoite protein, L9 Fab heavy chain, L9 Fab light chain 著者 Tripathi, P, Kwong, P.D. 登録日 2022-09-20 公開日 2023-03-15 最終更新日 2023-09-27 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Cryo-EM structures of anti-malarial antibody L9 with circumsporozoite protein reveal trimeric L9 association and complete 27-residue epitope. Structure, 31, 2023
8EK8	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAAAGGAGAAGGG) 分子名称: DNA (5'-D(*AP*TP*AP*AP*AP*AP*GP*GP*AP*GP*AP*AP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*TP*TP*CP*TP*CP*CP*TP*TP*TP*TP*AP*T)-3'), Transcription factor PU.1 著者 Terrell, J.R, Poon, G.M.K. 登録日 2022-09-20 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8EK5	Engineered scFv 10LH bound to PHOX2B/HLA-A24:02 分子名称: 10LH single chain fragment variable (scFv), Beta-2-microglobulin, GLYCEROL, ... 著者 Garfinkle, S.E, Florio, T.J, Sgourakis, N.G. 登録日 2022-09-20 公開日 2023-12-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion. Sci Immunol, 8, 2023

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