PDB: 5515 件ウェブページステータス検索Chemie searchBIRD

---

8DEP	Cryo-EM structure of the human reduced folate carrier, apo condition 分子名称: Digitonin, Reduced folate transporter,Soluble cytochrome b562 著者 Wright, N.J, Fedor, J.G, Lee, S.-Y. 登録日 2022-06-21 公開日 2022-09-21 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Methotrexate recognition by the human reduced folate carrier SLC19A1. Nature, 609, 2022
7QAZ	Prim-Pol Domain of CRISPR-associated Prim-Pol (CAPP) from Marinitoga sp. 1137 - Primer Initiation Complex 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, COBALT (II) ION, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Li, A.W.H, Doherty, A.J. 登録日 2021-11-17 公開日 2022-05-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Molecular basis for the initiation of DNA primer synthesis. Nature, 605, 2022
7TIO	B Domain of Staphylococcal protein A: Native backbone 分子名称: Immunoglobulin G binding protein A 著者 Santhouse, J.R, Leung, J.M.G, Chong, L.T, Horne, W.S. 登録日 2022-01-14 公開日 2022-11-23 実験手法 SOLUTION NMR 主引用文献 Implications of the unfolded state in the folding energetics of heterogeneous-backbone protein mimetics. Chem Sci, 13, 2022
7TIR	Backbone-modified variant of the B domain of Staphylococcal protein A: beta3-residues in helix 3 分子名称: Immunoglobulin G binding protein A 著者 Santhouse, J.R, Leung, J.M.G, Chong, L.T, Horne, W.S. 登録日 2022-01-14 公開日 2022-12-21 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Implications of the unfolded state in the folding energetics of heterogeneous-backbone protein mimetics. Chem Sci, 13, 2022
7TIP	Backbone-modified variant of the B domain of Staphylococcal protein A: beta3-residues in helix 2 分子名称: Immunoglobulin G binding protein A 著者 Santhouse, J.R, Leung, J.M.G, Chong, L.T, Horne, W.S. 登録日 2022-01-14 公開日 2022-12-21 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Implications of the unfolded state in the folding energetics of heterogeneous-backbone protein mimetics. Chem Sci, 13, 2022
7TIS	Backbone-modified variant of the B domain of Staphylococcal protein A: Aib residues in helix 3 分子名称: Immunoglobulin G binding protein A 著者 Santhouse, J.R, Leung, J.M.G, Chong, L.T, Horne, W.S. 登録日 2022-01-14 公開日 2022-12-21 実験手法 SOLUTION NMR 主引用文献 Implications of the unfolded state in the folding energetics of heterogeneous-backbone protein mimetics. Chem Sci, 13, 2022
7TIQ	Backbone-modified variant of the B domain of Staphylococcal protein A: Aib residues in helix 2 分子名称: Immunoglobulin G binding protein A 著者 Santhouse, J.R, Leung, J.M.G, Chong, L.T, Horne, W.S. 登録日 2022-01-14 公開日 2022-12-21 実験手法 SOLUTION NMR 主引用文献 Implications of the unfolded state in the folding energetics of heterogeneous-backbone protein mimetics. Chem Sci, 13, 2022
7URG	cryo-EM structure of ribonucleotide reductase from Synechococcus phage S-CBP4 bound with TTP 分子名称: Ribonucleotide reductase, THYMIDINE-5'-TRIPHOSPHATE 著者 Xu, D, Burnim, A.A, Ando, N. 登録日 2022-04-21 公開日 2022-09-07 最終更新日 2022-10-05 実験手法 ELECTRON MICROSCOPY (3.46 Å) 主引用文献 Comprehensive phylogenetic analysis of the ribonucleotide reductase family reveals an ancestral clade. Elife, 11, 2022
5WS5	Native XFEL structure of photosystem II (preflash dark dataset) 分子名称: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... 著者 Suga, M, Shen, J.R. 登録日 2016-12-05 公開日 2017-03-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Light-induced structural changes and the site of O=O bond formation in PSII caught by XFEL. Nature, 543, 2017
7UHY	Human GATOR2 complex 分子名称: GATOR complex protein MIOS, GATOR complex protein WDR24, GATOR complex protein WDR59, ... 著者 Rogala, K.B, Valenstein, M.L, Lalgudi, P.V. 登録日 2022-03-27 公開日 2022-07-20 最終更新日 2022-08-03 実験手法 ELECTRON MICROSCOPY (3.66 Å) 主引用文献 Structure of the nutrient-sensing hub GATOR2. Nature, 607, 2022
7RIV	human PXR LBD bound to GSK001 分子名称: Dabrafenib, Isoform 1C of Nuclear receptor subfamily 1 group I member 2 著者 Williams, S.P, Wisely, G.B, Ward, P. 登録日 2021-07-20 公開日 2021-08-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Overcoming the Pregnane X Receptor Liability: Rational Design to Eliminate PXR-Mediated CYP Induction. Acs Med.Chem.Lett., 12, 2021
7RIO	human PXR LBD bound to GSK003 分子名称: Isoform 1C of Nuclear receptor subfamily 1 group I member 2, N-[3-(2-tert-butyl-5-{2-[2-(methanesulfonyl)ethyl]pyrimidin-4-yl}-1,3-thiazol-4-yl)-2-fluorophenyl]-2,5-difluorobenzene-1-sulfonamide 著者 Williams, S.P, Wisely, G.B, Ward, P. 登録日 2021-07-20 公開日 2021-08-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Overcoming the Pregnane X Receptor Liability: Rational Design to Eliminate PXR-Mediated CYP Induction. Acs Med.Chem.Lett., 12, 2021
7RTK	Structure of the (NIAU)2 complex with N-terminal mutation of ISCU2 Y35D at 2.5 A resolution 分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, ... 著者 Boniecki, M.T, Cygler, M. 登録日 2021-08-13 公開日 2021-08-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The essential function of ISCU2 and its conserved N-terminus in Fe/S cluster biogenesis To Be Published
7RIU	human PXR LBD bound to GSK002 分子名称: Isoform 1C of Nuclear receptor subfamily 1 group I member 2, N-{3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl}thiophene-3-sulfonamide 著者 Williams, S.P, Wisely, G.B, Ward, P. 登録日 2021-07-20 公開日 2021-08-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Overcoming the Pregnane X Receptor Liability: Rational Design to Eliminate PXR-Mediated CYP Induction. Acs Med.Chem.Lett., 12, 2021
7V0F	Structure of 6-carboxy-5,6,7,8-tetrahydropterin synthase paralog QueD2 from Acinetobacter baumannii 分子名称: 1,2-ETHANEDIOL, 6-carboxy-5,6,7,8-tetrahydropterin synthase, DI(HYDROXYETHYL)ETHER, ... 著者 Jordan, M.R, Gonzalez-Gutierrez, G, Giedroc, D.P. 登録日 2022-05-10 公開日 2022-12-07 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Metal retention and replacement in QueD2 protect queuosine-tRNA biosynthesis in metal-starved Acinetobacter baumannii. Proc.Natl.Acad.Sci.USA, 119, 2022
7UKJ	In situ cryo-EM structure of bacteriophage Sf6 portal:gp7 complex at 2.7A resolution 分子名称: Gene 14 protein 著者 Li, F, Cingolani, G, Hou, C. 登録日 2022-04-01 公開日 2022-12-21 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 High-resolution cryo-EM structure of the Shigella virus Sf6 genome delivery tail machine. Sci Adv, 8, 2022
7R9D	Crystal structure of Nb_0 in complex with Fab_8D3 分子名称: Fab 8D3 heavy chain, Fab 8D3 light chain, Nanobody N0 著者 Wu, X.D, Rapoport, T.A. 登録日 2021-06-29 公開日 2021-10-06 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Cryo-EM structure determination of small proteins by nanobody-binding scaffolds (Legobodies). Proc.Natl.Acad.Sci.USA, 118, 2021
7RFB	Crystal structure of broadly neutralizing antibody mAb1198 in complex with Hepatitis C virus envelope glycoprotein E2 ectodomain 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Flyak, A.I, Bjorkman, P.J. 登録日 2021-07-14 公開日 2022-01-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Analysis of antibodies from HCV elite neutralizers identifies genetic determinants of broad neutralization. Immunity, 55, 2022
7RFC	Crystal structure of broadly neutralizing antibody mAb1382 in complex with Hepatitis C virus envelope glycoprotein E2 ectodomain 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Flyak, A.I, Bjorkman, P.J. 登録日 2021-07-14 公開日 2022-01-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.24 Å) 主引用文献 Analysis of antibodies from HCV elite neutralizers identifies genetic determinants of broad neutralization. Immunity, 55, 2022
8E4Y	Cryo-EM structure of human glycerol-3-phosphate acyltransferase 1 (GPAT1) in complex with 2-oxohexadecyl-CoA 分子名称: (2R)-2-hydroxy-3-(phosphonooxy)propyl hexadecanoate, Glycerol-3-phosphate acyltransferase 1, mitochondrial, ... 著者 Johnson, Z.L, Wasilko, D.J, Ammirati, M, Chang, J.S, Han, S, Wu, H. 登録日 2022-08-19 公開日 2022-12-21 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural basis of the acyl-transfer mechanism of human GPAT1. Nat.Struct.Mol.Biol., 30, 2023
8E50	Cryo-EM structure of human glycerol-3-phosphate acyltransferase 1 (GPAT1) in complex with CoA and palmitoyl-LPA 分子名称: (2R)-2-hydroxy-3-(phosphonooxy)propyl hexadecanoate, COENZYME A, Glycerol-3-phosphate acyltransferase 1, ... 著者 Wasilko, D.J, Johnson, Z.L, Ammirati, M, Chang, J.S, Han, S, Wu, H. 登録日 2022-08-19 公開日 2022-12-21 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.67 Å) 主引用文献 Structural basis of the acyl-transfer mechanism of human GPAT1. Nat.Struct.Mol.Biol., 30, 2023
7R79	Histoplasma capsulatum H88 Calcium Binding Protein 1 (Cbp1) 分子名称: Calcium-binding protein 著者 Herrera, N, Azimova, D, Sil, A, Rosenberg, O.S. 登録日 2021-06-24 公開日 2022-04-13 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Cbp1, a fungal virulence factor under positive selection, forms an effector complex that drives macrophage lysis. Plos Pathog., 18, 2022
7R6U	Paracoccidioides americana Pb03 Calcium Binding Protein 1 (Cbp1) 分子名称: CBP domain-containing protein 著者 Herrera, N, Azimova, D, Sil, A, Rosenberg, O.S. 登録日 2021-06-23 公開日 2022-04-13 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Cbp1, a fungal virulence factor under positive selection, forms an effector complex that drives macrophage lysis. Plos Pathog., 18, 2022
7R6N	Exon-free state of the Tetrahymena group I intron, symmetry-expanded monomer from a synthetic trimeric construct 分子名称: Group I intron, MAGNESIUM ION 著者 Thelot, F, Liu, D, Liao, M, Yin, P. 登録日 2021-06-22 公開日 2022-05-04 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Sub-3- angstrom cryo-EM structure of RNA enabled by engineered homomeric self-assembly. Nat.Methods, 19, 2022
7R6M	Post-2S intermediate of the Tetrahymena group I intron, symmetry-expanded monomer from a synthetic dimeric construct 分子名称: Group I intron, Ligated exon mimic of the Group I intron, MAGNESIUM ION 著者 Thelot, F, Liu, D, Liao, M, Yin, P. 登録日 2021-06-22 公開日 2022-05-04 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.68 Å) 主引用文献 Sub-3- angstrom cryo-EM structure of RNA enabled by engineered homomeric self-assembly. Nat.Methods, 19, 2022

<196197198199200201202203204205206207208209210211>