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2LB3
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BU of 2lb3 by Molmil
Structure of the WW domain of PIN1 in complex with a human phosphorylated Smad3 derived peptide
分子名称: Mothers against decapentaplegic homolog 2, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J.
登録日2011-03-22
公開日2011-07-06
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
4ZFJ
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BU of 4zfj by Molmil
Ergothioneine-biosynthetic Ntn hydrolase EgtC, apo form
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL, Amidohydrolase EgtC
著者Vit, A, Seebeck, F.P, Blankenfeldt, W.
登録日2015-04-21
公開日2015-07-01
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure of the Ergothioneine-Biosynthesis Amidohydrolase EgtC.
Chembiochem, 16, 2015
7P71
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BU of 7p71 by Molmil
The PDZ domain of MAGI1_2 complexed with the PDZ-binding motif of HPV35-E6
分子名称: CALCIUM ION, CITRIC ACID, GLYCEROL, ...
著者Gogl, G, Cousido-Siah, A, Trave, G.
登録日2021-07-19
公開日2022-07-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Quantitative fragmentomics allow affinity mapping of interactomes.
Nat Commun, 13, 2022
1G3P
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BU of 1g3p by Molmil
CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAINS OF BACTERIOPHAGE MINOR COAT PROTEIN G3P
分子名称: MINOR COAT PROTEIN, SULFATE ION
著者Lubkowski, J, Hennecke, F, Pluckthun, A, Wlodawer, A.
登録日1997-12-22
公開日1998-01-28
最終更新日2019-08-14
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献The structural basis of phage display elucidated by the crystal structure of the N-terminal domains of g3p.
Nat.Struct.Biol., 5, 1998
8B5L
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BU of 8b5l by Molmil
Cryo-EM structure of ribosome-Sec61-TRAP (TRanslocon Associated Protein) translocon complex
分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Pauwels, E, Shewakramani, N.R, De Wijngaert, B, Vermeire, K, Das, K.
登録日2022-09-23
公開日2023-03-01
最終更新日2023-03-15
実験手法ELECTRON MICROSCOPY (2.86 Å)
主引用文献Structural insights into TRAP association with ribosome-Sec61 complex and translocon inhibition by a CADA derivative.
Sci Adv, 9, 2023
8B6C
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BU of 8b6c by Molmil
Cryo-EM structure of ribosome-Sec61 in complex with cyclotriazadisulfonamide derivative CK147
分子名称: 28S rRNA, 4-[[9-(cyclohexylmethyl)-3-methylidene-5-(4-methylphenyl)sulfonyl-1,5,9-triazacyclododec-1-yl]sulfonyl]-~{N},~{N}-dimethyl-aniline, 5.8S rRNA, ...
著者Pauwels, E, Shewakramani, N.R, De Wijngaert, B, Vermeire, K, Das, K.
登録日2022-09-26
公開日2023-02-22
最終更新日2023-03-15
実験手法ELECTRON MICROSCOPY (2.79 Å)
主引用文献Structural insights into TRAP association with ribosome-Sec61 complex and translocon inhibition by a CADA derivative.
Sci Adv, 9, 2023
1GKF
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BU of 1gkf by Molmil
Crystal structures of penicillin acylase enzyme-substrate complexes: Structural insights into the catalytic mechanism
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, PENICILLIN G ACYLASE ALPHA SUBUNIT, ...
著者McVey, C.E, Walsh, M.A, Dodson, G.G, Wilson, K.S, Brannigan, J.A.
登録日2001-08-13
公開日2002-01-04
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Crystal Structures of Penicillin Acylase Enzyme- Substrate Complexes: Structural Insights Into the Catalytic Mechanism
J.Mol.Biol., 313, 2001
1GK9
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BU of 1gk9 by Molmil
Crystal structures of penicillin acylase enzyme-substrate complexes: Structural insights into the catalytic mechanism
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, PENICILLIN G ACYLASE ALPHA SUBUNIT, ...
著者McVey, C.E, Walsh, M.A, Dodson, G.G, Wilson, K.S, Brannigan, J.A.
登録日2001-08-10
公開日2002-01-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal Structures of Penicillin Acylase Enzyme-Substrate Complexes: Structural Insights Into the Catalytic Mechanism
J.Mol.Biol., 313, 2001
5OOM
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BU of 5oom by Molmil
Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded interfacial rRNA
分子名称: 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ...
著者Brown, A, Rathore, S, Kimanius, D, Aibara, S, Bai, X.C, Rorbach, J, Amunts, A, Ramakrishnan, V.
登録日2017-08-08
公開日2017-09-13
最終更新日2023-03-15
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献Structures of the human mitochondrial ribosome in native states of assembly.
Nat. Struct. Mol. Biol., 24, 2017
2LXM
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BU of 2lxm by Molmil
Lip5-chmp5
分子名称: Charged multivesicular body protein 5, Vacuolar protein sorting-associated protein VTA1 homolog
著者Skalicky, J.J, Sundquist, W.I.
登録日2012-08-29
公開日2012-11-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Interactions of the Human LIP5 Regulatory Protein with Endosomal Sorting Complexes Required for Transport.
J.Biol.Chem., 287, 2012
2MDJ
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BU of 2mdj by Molmil
Solution structure of WW domain with polyproline stretch (PP2WW) of HYPB
分子名称: Histone-lysine N-methyltransferase SETD2
著者Gao, Y, Hu, H.
登録日2013-09-11
公開日2014-09-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Autoinhibitory structure of the WW domain of HYPB/SETD2 regulates its interaction with the proline-rich region of huntingtin
Structure, 22, 2014
2MDC
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BU of 2mdc by Molmil
Solution structure of the WW domain of HYPB
分子名称: Histone-lysine N-methyltransferase SETD2
著者Gao, Y.G.
登録日2013-09-10
公開日2014-09-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Autoinhibitory structure of the WW domain of HYPB/SETD2 regulates its interaction with the proline-rich region of huntingtin
Structure, 22, 2014
7W3O
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BU of 7w3o by Molmil
Crystal structure of human CYB5R3
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, NADH-cytochrome b5 reductase 3 soluble form
著者Noda, N.N.
登録日2021-11-25
公開日2022-12-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献The UFM1 system regulates ER-phagy through the ufmylation of CYB5R3.
Nat Commun, 13, 2022
7D0E
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BU of 7d0e by Molmil
Crystal structure of FIP200 Claw/p-CCPG1 FIR2
分子名称: 3-(2-hydroxyethyloxy)-2-[2-(2-hydroxyethyloxy)ethoxymethyl]-2-(2-hydroxyethyloxymethyl)propan-1-ol, Cell cycle progression protein 1 FIR2, DI(HYDROXYETHYL)ETHER, ...
著者Zhou, Z.X, Pan, L.F.
登録日2020-09-09
公開日2021-03-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Phosphorylation regulates the binding of autophagy receptors to FIP200 Claw domain for selective autophagy initiation.
Nat Commun, 12, 2021
7CZG
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BU of 7czg by Molmil
Crystal structure of FIP200 Claw domain apo form
分子名称: DI(HYDROXYETHYL)ETHER, RB1-inducible coiled-coil protein 1
著者Zhou, Z.X, Pan, L.F.
登録日2020-09-08
公開日2021-03-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Phosphorylation regulates the binding of autophagy receptors to FIP200 Claw domain for selective autophagy initiation.
Nat Commun, 12, 2021
7CZM
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BU of 7czm by Molmil
Crystal structure of FIP200 Claw/p-OPtineurin LIR complex
分子名称: CHLORIDE ION, GLYCEROL, Optineurin LIR, ...
著者Zhou, Z.X, Pan, L.F.
登録日2020-09-09
公開日2021-03-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Phosphorylation regulates the binding of autophagy receptors to FIP200 Claw domain for selective autophagy initiation.
Nat Commun, 12, 2021
7UOO
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BU of 7uoo by Molmil
Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ...
著者Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P.
登録日2022-04-13
公開日2023-03-15
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.34 Å)
主引用文献rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly.
Nat Commun, 14, 2023
7UQZ
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BU of 7uqz by Molmil
Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a SPB1 D52A strain
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ...
著者Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P.
登録日2022-04-20
公開日2023-03-15
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.44 Å)
主引用文献rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly.
Nat Commun, 14, 2023
7UQB
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BU of 7uqb by Molmil
Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a SPB1-D52A strain with AlF4
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ...
著者Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P.
登録日2022-04-19
公開日2023-03-15
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.43 Å)
主引用文献rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly.
Nat Commun, 14, 2023
7V08
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BU of 7v08 by Molmil
Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a Spb1 D52A suppressor 3 strain
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ...
著者Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P.
登録日2022-05-10
公開日2023-03-15
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.36 Å)
主引用文献rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly.
Nat Commun, 14, 2023
3HVC
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BU of 3hvc by Molmil
Crystal structure of human p38alpha MAP kinase
分子名称: 4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE, Mitogen-activated protein kinase 14
著者Perry, J.J, Tainer, J.A.
登録日2009-06-15
公開日2009-06-30
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献p38alpha MAP kinase C-terminal domain binding pocket characterized by crystallographic and computational analyses.
J.Mol.Biol., 391, 2009
2WCV
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BU of 2wcv by Molmil
Crystal structure of bacterial FucU
分子名称: L-FUCOSE MUTAROTASE, alpha-L-fucopyranose
著者Lee, K.-H, Kim, M.-S, Suh, H.-Y, Ku, B, Song, Y.-L, Oh, B.-H.
登録日2009-03-17
公開日2009-11-10
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structures and Enzyme Mechanism of a Dual Fucose Mutarotase/Ribose Pyranase
J.Mol.Biol., 391, 2009
5XJL
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BU of 5xjl by Molmil
Crystal Structure of the Gemin2-binding domain of SMN, Gemin2 in Complex with SmD1/D2/F/E/G from Human
分子名称: Gem-associated protein 2, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, ...
著者Zhang, R.
登録日2017-05-02
公開日2018-05-02
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of a key intermediate of the SMN complex reveals Gemin2's crucial function in snRNP assembly
Cell, 146, 2011
2WCU
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BU of 2wcu by Molmil
Crystal structure of mammalian FucU
分子名称: PROTEIN FUCU HOMOLOG, alpha-L-fucopyranose
著者Lee, K.-H, Kim, M.-S, Suh, H.-Y, Ku, B, Song, Y.-L, Oh, B.-H.
登録日2009-03-17
公開日2009-11-10
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structures and Enzyme Mechanism of a Dual Fucose Mutarotase/Ribose Pyranase
J.Mol.Biol., 391, 2009
2LEH
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BU of 2leh by Molmil
Solution structure of the core SMN-Gemin2 complex
分子名称: Survival motor neuron protein, Survival of motor neuron protein-interacting protein 1
著者Sarachan, K.L, Valentine, K, Gupta, K, Moorman, V, Gledhill, J, Bernens, M, Tommos, C, Wand, A.J, Van Duyne, G.
登録日2011-06-15
公開日2012-06-27
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of the core SMN-Gemin2 complex.
Biochem.J., 445, 2012

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