8YOU
 
 | | The pmTcDH complex structure with an inhibitor SeCN | | 分子名称: | COPPER (II) ION, GLYCEROL, SELENIUM ATOM, ... | | 著者 | Varfolomeeva, L.A, Polyakov, K.M, Shipkov, N.S, Dergousova, N.I, Boyko, K.M, Tikhonova, T.V, Popov, V.O. | | 登録日 | 2024-03-13 | | 公開日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The pmTcDH complex structure with an inhibitor SeCN
To Be Published
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8YNJ
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8YM7
 | | Crystal structure of Lysine Specific Demethylase 1 (LSD1) with JH-45 | | 分子名称: | 4-[5-(4-azanylpiperidin-1-yl)-8-(4-methylphenyl)pyrido[3,4-b]pyrazin-7-yl]-2-fluoranyl-benzenecarbonitrile, FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1A, ... | | 著者 | Zhiyan, D, Danyan, C, Hong, J, Tongchao, L, Bing, X. | | 登録日 | 2024-03-08 | | 公開日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | | 主引用文献 | Discovery of Novel LSD1 Inhibitors for the Treatment of Autosomal Dominant Polycystic Kidney Disease
To Be Published
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8YM2
 | | Crystal structure of AIDA-1 PTB domain in complex with SynGAP NPxF motif | | 分子名称: | Ankyrin repeat and sterile alpha motif domain-containing protein 1B, Ras/Rap GTPase-activating protein SynGAP | | 著者 | Wang, X, Wang, Y, Cai, Q, Zhang, M. | | 登録日 | 2024-03-08 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | AIDA-1/ANKS1B Binds to the SynGAP Family RasGAPs with High Affinity and Specificity.
J.Mol.Biol., 436, 2024
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8YLZ
 | | Structure of a cis-Geranylfarnesyl Diphosphate Synthase from Streptomyces clavuligerus | | 分子名称: | Isoprenyl transferase | | 著者 | Li, F.R, Wang, Q.L, Pan, X.M, Dong, L.B. | | 登録日 | 2024-03-07 | | 公開日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Discovery, Structure, and Engineering of a cis-Geranylfarnesyl Diphosphate Synthase.
Angew.Chem.Int.Ed.Engl., 2024
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8YLE
 | | Crystal structure of Werner syndrome helicase complexed with AMP-PCP | | 分子名称: | 1,2-ETHANEDIOL, Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | | 著者 | Yang, Y, Fu, L, Sun, X, Cheng, H, Chen, R. | | 登録日 | 2024-03-06 | | 公開日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Structure of werner syndrome helicase complexed with AMP-PCP at 1.86 Angstroms resolution.
To Be Published
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8YLC
 | | The crystal structure of PDE4D with Amentoflavone | | 分子名称: | 3',5'-cyclic-AMP phosphodiesterase 4D, 8-[5-[5,7-bis(oxidanyl)-4-oxidanylidene-chromen-2-yl]-2-oxidanyl-phenyl]-2-(4-hydroxyphenyl)-5,7-bis(oxidanyl)chromen-4-one, MAGNESIUM ION, ... | | 著者 | Huang, Y.-Y, Luo, H.-B. | | 登録日 | 2024-03-06 | | 公開日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (2.30003715 Å) | | 主引用文献 | Discovery of amentoflavone as a natural PDE4 inhibitor with anti-fibrotic effects
Chin.Chem.Lett., 2024
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8YLB
 | | Cocrystal structures of agonists compound 1 with HsClpP | | 分子名称: | 5-[(2-methylphenyl)methyl]-11-(phenylmethyl)-2,5,7,11-tetrazatricyclo[7.4.0.0^{2,6}]trideca-1(9),6-dien-8-one, ATP-dependent Clp protease proteolytic subunit, mitochondrial | | 著者 | Zhao, N, Zhu, Y, Bao, R. | | 登録日 | 2024-03-06 | | 公開日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Rational Design of a Novel Class of Human ClpP Agonists through a Ring-Opening Strategy with Enhanced Antileukemia Activity.
J.Med.Chem., 67, 2024
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8YLA
 | | Crystal structures of terpene synthases complexed with a substrate mimic | | 分子名称: | MAGNESIUM ION, N-benzyl-N,N-diethylethanaminium, PYROPHOSPHATE, ... | | 著者 | Xu, M, Ma, M. | | 登録日 | 2024-03-05 | | 公開日 | 2024-04-24 | | 最終更新日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structural Insights Into the Terpene Cyclization Domains of Two Fungal Sesterterpene Synthases and Enzymatic Engineering for Sesterterpene Diversification.
Angew.Chem.Int.Ed.Engl., 63, 2024
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8YL9
 | | Crystal structures of terpene synthases complexed with a substrate mimic | | 分子名称: | MAGNESIUM ION, N-benzyl-N,N-diethylethanaminium, PYROPHOSPHATE, ... | | 著者 | Xu, M, Ma, M. | | 登録日 | 2024-03-05 | | 公開日 | 2024-04-24 | | 最終更新日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structural Insights Into the Terpene Cyclization Domains of Two Fungal Sesterterpene Synthases and Enzymatic Engineering for Sesterterpene Diversification.
Angew.Chem.Int.Ed.Engl., 63, 2024
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8YKX
 | | Cryo-EM structure of succinate receptor SUCR1 bound to maleic acid | | 分子名称: | Antibody fragment ScFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Li, C, Liu, H, Li, J, Zhu, H, Fu, W, Xu, H.E. | | 登録日 | 2024-03-05 | | 公開日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.69 Å) | | 主引用文献 | Cryo-EM structure of succinate receptor SUCR1 bound to maleic acid
To Be Published
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8YKW
 | | Cryo-EM structure of succinate receptor SUCR1 bound to succinic acid | | 分子名称: | Antibody fragment ScFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Li, C, Liu, H, Li, J, Zhu, H, Fu, W, Xu, H.E. | | 登録日 | 2024-03-05 | | 公開日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | | 主引用文献 | Cryo-EM structure of succinate receptor SUCR1 bound to succinic acid
To Be Published
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8YKV
 | | Cryo-EM structure of succinate receptor SUCR1 bound to compound 31 | | 分子名称: | (2~{S})-2-[[6-[4-(trifluoromethyloxy)phenyl]pyridin-2-yl]carbonylamino]butanedioic acid, Antibody fragment ScFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Li, C, Liu, H, Li, J, Zhu, H, Fu, W, Xu, H.E. | | 登録日 | 2024-03-05 | | 公開日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.48 Å) | | 主引用文献 | Cryo-EM structure of succinate receptor SUCR1 bound to compound 31
To Be Published
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8YKI
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8YK5
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8YJY
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8YJX
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8YJM
 | | Structure of human SPT16 MD-CTD and MCM2 HBD chaperoning a histone H3-H4 tetramer and a single chain H2B-H2A chimera | | 分子名称: | DNA replication licensing factor MCM2, FACT complex subunit SPT16, Histone H2B 1/2/3/4/6,Histone H2A type 1-D, ... | | 著者 | Gan, S.L, Yang, W.S, Xu, R.M. | | 登録日 | 2024-03-02 | | 公開日 | 2024-03-20 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (4.15 Å) | | 主引用文献 | Structure of a histone hexamer bound by the chaperone domains of SPT16 and MCM2.
Sci China Life Sci, 2024
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8YJJ
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8YJI
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8YJF
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8YIB
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8YHW
 | | The Crystal Structure of NF-kB-inducing Kinase (NIK) from Biortus | | 分子名称: | 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, MAGNESIUM ION, ... | | 著者 | Wang, F, Cheng, W, Lv, Z, Meng, Q, Xu, Y. | | 登録日 | 2024-02-28 | | 公開日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | The Crystal Structure of NF-kB-inducing Kinase (NIK) from Biortus
To Be Published
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8YHV
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8YHS
 | | The Crystal Structure of BRDT from Biortus. | | 分子名称: | 1,2-ETHANEDIOL, 2,4-dimethyl-6-[6-(oxan-4-yl)-1-[(1~{S})-1-phenylethyl]imidazo[4,5-c]pyridin-2-yl]pyridazin-3-one, Bromodomain testis-specific protein | | 著者 | Wang, F, Cheng, W, Lv, Z, Meng, Q, Lu, Y. | | 登録日 | 2024-02-28 | | 公開日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The Crystal Structure of BRDT from Biortus.
To Be Published
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