PDB: 48 件ウェブページステータス検索Chemie searchBIRD

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4TU8	STRUCTURE OF U2AF65 VARIANT WITH BRU5A6 DNA 分子名称: 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*UP*UP*UP*UP*(BRU)P*DA*U)-3'), ... 著者 MCLAUGHLIN, K.J, JENKINS, J.L, Agrawal, A.A, KIELKOPF, C.L. 登録日 2014-06-24 公開日 2014-11-26 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.918 Å) 主引用文献 Structure-guided U2AF65 variant improves recognition and splicing of a defective pre-mRNA. Proc.Natl.Acad.Sci.USA, 111, 2014
4TU7	Structure of U2AF65 D231V variant with BrU5 DNA 分子名称: 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*UP*UP*UP*UP*(BRU)P*UP*U)-3'), GLYCEROL, ... 著者 Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L. 登録日 2014-06-24 公開日 2014-11-26 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.087 Å) 主引用文献 Structure-guided U2AF65 variant improves recognition and splicing of a defective pre-mRNA. Proc.Natl.Acad.Sci.USA, 111, 2014
4RU2	Crystal structure of a RNA-binding protein 39 (RBM39) in complex with fragment of splicing factor (U2AF) from Mus musculus at 2.20 A resolution 分子名称: RNA-binding protein 39 (RBM39), Splicing factor U2AF 65 kDa subunit 著者 Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) 登録日 2014-11-17 公開日 2015-02-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of a RNA-binding protein 39 (RBM39) in complex with fragment of splicing factor (U2AF) from Mus musculus at 2.20 A resolution To be published
5CXT	Crystal structure of a RNA-binding protein 39 (RBM39) in complex with fragment of splicing factor (U2AF) from Unknown at 2.20 A resolution 分子名称: RNA-binding protein 39, Splicing factor U2AF 65 kDa subunit 著者 Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) 登録日 2015-07-29 公開日 2015-10-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 UHM-ULM interactions in the RBM39-U2AF65 splicing-factor complex. Acta Crystallogr D Struct Biol, 72, 2016
5EV1	Structure I of Intact U2AF65 Recognizing a 3' Splice Site Signal 分子名称: DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(*UP*UP*U)-D(P*UP*UP*(BRU)P*U)-R(P*UP*U)-3'), SODIUM ION, ... 著者 Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L. 登録日 2015-11-19 公開日 2016-02-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.037 Å) 主引用文献 An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal. Nat Commun, 7, 2016
5EV2	Structure II of Intact U2AF65 Recognizing the 3' Splice Site Signal 分子名称: 1,4-DIETHYLENE DIOXIDE, DI(HYDROXYETHYL)ETHER, DNA (5'-R(P*UP*U)-D(P*UP*U)-R(P*U)-D(P*UP*(BRU)P*U)-3'), ... 著者 Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L. 登録日 2015-11-19 公開日 2016-02-24 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal. Nat Commun, 7, 2016
5EV3	Structure III of Intact U2AF65 Recognizing the 3' Splice Site Signal 分子名称: DNA/RNA (5'-R(P*UP*U)-D(P*U)-R(P*UP*U)-D(P*(BRU)P*UP*U)-3'), Splicing factor U2AF 65 kDa subunit 著者 Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L. 登録日 2015-11-19 公開日 2016-02-24 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal. Nat Commun, 7, 2016
5EV4	Structure IV of Intact U2AF65 Recognizing the 3' Splice Site Signal 分子名称: DNA/RNA (5'-R(P*UP*UP*UP*(UD)P*UP*U)-D(P*(BRU)P*(UD))-R(P*C)-3'), GLYCEROL, Splicing factor U2AF 65 kDa subunit 著者 Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L. 登録日 2015-11-19 公開日 2016-02-24 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal. Nat Commun, 7, 2016
2G4B	Structure of U2AF65 variant with polyuridine tract 分子名称: 1,4-DIETHYLENE DIOXIDE, 5'-R(P*UP*UP*UP*UP*UP*UP*U)-3', Splicing factor U2AF 65 kDa subunit 著者 Sickmier, E.A, Kielkopf, C.L. 登録日 2006-02-21 公開日 2006-07-25 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis of polypyrimidine tract recognition by the essential splicing factor U2AF65. Mol.Cell, 23, 2006
2YH0	Solution structure of the closed conformation of human U2AF65 tandem RRM1 and RRM2 domains 分子名称: SPLICING FACTOR U2AF 65 KDA SUBUNIT 著者 Mackereth, C.D, Madl, T, Simon, B, Zanier, K, Gasch, A, Sattler, M. 登録日 2011-04-26 公開日 2011-07-20 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Multi-Domain Conformational Selection Underlies Pre-Mrna Splicing Regulation by U2Af Nature, 475, 2011
2YH1	Model of human U2AF65 tandem RRM1 and RRM2 domains with eight-site uridine binding 分子名称: 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP)-3', SPLICING FACTOR U2AF 65 KDA SUBUNIT 著者 Mackereth, C.D, Madl, T, Simon, B, Zanier, K, Gasch, A, Sattler, M. 登録日 2011-04-26 公開日 2011-07-20 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Multi-Domain Conformational Selection Underlies Pre-Mrna Splicing Regulation by U2Af Nature, 475, 2011
7C06	Crystal structure of yeast U2AF1 complex bound to 3' splice site RNA, 5'-UAGGU. 分子名称: RNA (5'-R(*U*UP*AP*GP*GP*U)-3'), Splicing factor U2AF 23 kDa subunit, Splicing factor U2AF 59 kDa subunit, ... 著者 Yoshida, H, Park, S.Y, Urano, T, Obayashi, E. 登録日 2020-04-30 公開日 2020-09-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.02 Å) 主引用文献 Elucidation of the aberrant 3' splice site selection by cancer-associated mutations on the U2AF1. Nat Commun, 11, 2020
7C08	Crystal structure of S34Y mutant of yeast U2AF1 complex bound to 3' splice site RNA, 5'-UAGGU. 分子名称: RNA (5'-R(*U*UP*AP*GP*GP*U)-3'), Splicing factor U2AF 23 kDa subunit, Splicing factor U2AF 59 kDa subunit, ... 著者 Yoshida, H, Park, S.Y, Urano, T, Obayashi, E. 登録日 2020-04-30 公開日 2020-09-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 Elucidation of the aberrant 3' splice site selection by cancer-associated mutations on the U2AF1. Nat Commun, 11, 2020
7C07	Crystal structure of yeast U2AF1 complex bound to 5'-AAGGU RNA. 分子名称: RNA (5'-R(*U*AP*AP*GP*GP*U)-3'), Splicing factor U2AF 23 kDa subunit, Splicing factor U2AF 59 kDa subunit, ... 著者 Yoshida, H, Park, S.Y, Urano, T, Obayashi, E. 登録日 2020-04-30 公開日 2020-09-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Elucidation of the aberrant 3' splice site selection by cancer-associated mutations on the U2AF1. Nat Commun, 11, 2020
3VAK	Structure of U2AF65 variant with BrU5 DNA 分子名称: 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*UP*UP*UP*UP*(BRU)P*UP*U)-3'), GLYCEROL, ... 著者 Jenkins, J.L, Kielkopf, C.L. 登録日 2011-12-29 公開日 2013-02-13 最終更新日 2017-08-16 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res., 41, 2013
3VAF	Structure of U2AF65 variant with BrU3 DNA 分子名称: 1,4-DIETHYLENE DIOXIDE, DNA 5'-D(*UP*UP*(BRU)P*(BRU)P*UP*UP*U)-3', GLYCEROL, ... 著者 Jenkins, J.L, Kielkopf, C.L. 登録日 2011-12-29 公開日 2013-02-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res., 41, 2013
3VAM	Structure of U2AF65 variant with BrU5C2 DNA 分子名称: 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*UP*CP*UP*UP*(BRU)P*UP*U)-3'), GLYCEROL, ... 著者 Jenkins, J.L, Kielkopf, C.L. 登録日 2011-12-29 公開日 2013-02-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res., 41, 2013
3VAJ	Structure of U2AF65 variant with BrU5C6 DNA 分子名称: 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*UP*UP*UP*UP*(BRU)P*CP*U)-3'), GLYCEROL, ... 著者 Jenkins, J.L, Kielkopf, C.L. 登録日 2011-12-29 公開日 2013-02-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res., 41, 2013
3VAI	Structure of U2AF65 variant with BrU3C5 DNA 分子名称: 1,4-DIETHYLENE DIOXIDE, DNA 5'-D(*UP*UP*(BRU)P*UP*CP*UP*U)-3', GLYCEROL, ... 著者 Jenkins, J.L, Frato, K.H, Kielkopf, C.L. 登録日 2011-12-29 公開日 2013-02-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res., 41, 2013
3V4M	Crystal structure of a RNA binding domain of a U2 small nuclear ribonucleoprotein auxiliary factor 2 (U2AF) from Mus musculus at 1.80 A resolution 分子名称: CHLORIDE ION, SODIUM ION, Splicing factor U2AF 65 kDa subunit 著者 Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) 登録日 2011-12-15 公開日 2012-06-13 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of a RNA binding domain of a U2 small nuclear ribonucleoprotein auxiliary factor 2 (U2AF) from Mus musculus at 1.80 A resolution To be published
3VAH	Structure of U2AF65 variant with BrU3C4 DNA 分子名称: 1,4-DIETHYLENE DIOXIDE, DNA 5'-D(P*UP*UP*(BRU)P*CP*UP*UP*U)-3', GLYCEROL, ... 著者 Jenkins, J.L, Kielkopf, C.L. 登録日 2011-12-29 公開日 2013-02-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res., 41, 2013
3VAL	Structure of U2AF65 variant with BrU5C1 DNA 分子名称: 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*C*UP*UP*UP*(BRU)P*UP*U)-3'), SULFATE ION, ... 著者 Jenkins, J.L, Frato, K.H, Kielkopf, C.L. 登録日 2011-12-29 公開日 2013-02-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res., 41, 2013
3VAG	Structure of U2AF65 variant with BrU3C2 DNA 分子名称: 1,4-DIETHYLENE DIOXIDE, DNA 5'-D(*U*CP*(BRU)P*UP*UP*UP*U)-3', GLYCEROL, ... 著者 Jenkins, J.L, Kielkopf, C.L. 登録日 2011-12-29 公開日 2013-02-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res., 41, 2013

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