8PK1
 
 | | Cas1-Cas2 CRISPR integrase bound to prespacer DNA, Streptococcus thermophilus DGCC 7710 CRISPR3 system | | 分子名称: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, Chains: G,J, ... | | 著者 | Sasnauskas, G, Gaizauskaite, U, Tamulaitiene, G. | | 登録日 | 2023-06-23 | | 公開日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | | 主引用文献 | Structural basis for spacer acquisition in a type II-A CRISPR-Cas system
To Be Published
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8Q2N
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6QXT
 | | Cas1-Cas2-Csn2-DNA dimer complex from the Type II-A CRISPR-Cas system | | 分子名称: | CALCIUM ION, CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, ... | | 著者 | Wilkinson, M, Drabavicius, G, Silanskas, A, Gasiunas, G, Siksnys, V, Wigley, D.B. | | 登録日 | 2019-03-08 | | 公開日 | 2019-05-08 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (8.9 Å) | | 主引用文献 | Structure of the DNA-Bound Spacer Capture Complex of a Type II CRISPR-Cas System.
Mol.Cell, 75, 2019
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6QY3
 | | Segment of the Cas1-Cas2-Csn2-DNA filament complex from the Type II-A CRISPR-Cas system | | 分子名称: | CALCIUM ION, CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, ... | | 著者 | Wilkinson, M, Drabavicius, G, Silanskas, A, Gasiunas, G, Siksnys, V, Wigley, D.B. | | 登録日 | 2019-03-08 | | 公開日 | 2019-05-08 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (9.1 Å) | | 主引用文献 | Structure of the DNA-Bound Spacer Capture Complex of a Type II CRISPR-Cas System.
Mol.Cell, 75, 2019
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6QXF
 | | Cas1-Cas2-Csn2-DNA complex from the Type II-A CRISPR-Cas system | | 分子名称: | CALCIUM ION, CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, ... | | 著者 | Wilkinson, M, Drabavicius, G, Silanskas, A, Gasiunas, G, Siksnys, V, Wigley, D.B. | | 登録日 | 2019-03-07 | | 公開日 | 2019-05-08 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structure of the DNA-Bound Spacer Capture Complex of a Type II CRISPR-Cas System.
Mol.Cell, 75, 2019
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7CR6
 | | Synechocystis Cas1-Cas2/prespacer binary complex | | 分子名称: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2 1, DNA (36-MER) | | 著者 | Yu, Y, Chen, Q. | | 登録日 | 2020-08-12 | | 公開日 | 2021-03-31 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.72 Å) | | 主引用文献 | Mechanisms of spacer acquisition by sequential assembly of the adaptation module in Synechocystis.
Nucleic Acids Res., 49, 2021
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7CR8
 | | Synechocystis Cas1-Cas2-prespacerL complex | | 分子名称: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2 1, DNA (36-MER) | | 著者 | Yu, Y, Chen, Q. | | 登録日 | 2020-08-12 | | 公開日 | 2021-03-31 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Mechanisms of spacer acquisition by sequential assembly of the adaptation module in Synechocystis.
Nucleic Acids Res., 49, 2021
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7EI1
 | | Structure of Pyrococcus furiosus Cas1Cas2 complex | | 分子名称: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2 | | 著者 | Yu, Y, Chen, Q. | | 登録日 | 2021-03-30 | | 公開日 | 2021-11-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | A distinct structure of Cas1-Cas2 complex provides insights into the mechanism for the longer spacer acquisition in Pyrococcus furiosus.
Int.J.Biol.Macromol., 183, 2021
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8D3Q
 | | Type I-C Cas4-Cas1-Cas2 complex bound to a PAM/NoPAM prespacer | | 分子名称: | CRISPR-associated endonuclease Cas1, CRISPR-associated endonuclease Cas2, CRISPR-associated exonuclease Cas4, ... | | 著者 | Dhingra, Y, Suresh, S.K, Juneja, P, Sashital, D.G. | | 登録日 | 2022-06-01 | | 公開日 | 2022-11-02 | | 最終更新日 | 2025-05-28 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | PAM binding ensures orientational integration during Cas4-Cas1-Cas2-mediated CRISPR adaptation.
Mol.Cell, 82, 2022
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8D3M
 | | Type I-C Cas4-Cas1-Cas2 complex bound to a PAM/Processed prespacer | | 分子名称: | CRISPR-associated endonuclease Cas1, CRISPR-associated endonuclease Cas2, CRISPR-associated exonuclease Cas4, ... | | 著者 | Dhingra, Y, Suresh, S.K, Juneja, P, Sashital, D.G. | | 登録日 | 2022-06-01 | | 公開日 | 2022-11-02 | | 最終更新日 | 2025-05-28 | | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | | 主引用文献 | PAM binding ensures orientational integration during Cas4-Cas1-Cas2-mediated CRISPR adaptation.
Mol.Cell, 82, 2022
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8D3L
 | | Type I-C Cas4-Cas1-Cas2 complex bound to a PAM/PAM prespacer | | 分子名称: | CRISPR-associated endonuclease Cas1, CRISPR-associated endonuclease Cas2, CRISPR-associated exonuclease Cas4, ... | | 著者 | Dhingra, Y, Suresh, S.K, Juneja, P, Sashital, D.G. | | 登録日 | 2022-06-01 | | 公開日 | 2022-11-02 | | 最終更新日 | 2025-05-28 | | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | | 主引用文献 | PAM binding ensures orientational integration during Cas4-Cas1-Cas2-mediated CRISPR adaptation.
Mol.Cell, 82, 2022
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8D3P
 | | Type I-C Cas4-Cas1-Cas2 complex bound to half-site integration intermediate (HSI) | | 分子名称: | CRISPR-associated endonuclease Cas1, CRISPR-associated endonuclease Cas2, CRISPR-associated exonuclease Cas4, ... | | 著者 | Dhingra, Y, Suresh, S.K, Juneja, P, Sashital, D.G. | | 登録日 | 2022-06-01 | | 公開日 | 2022-11-02 | | 最終更新日 | 2024-12-25 | | 実験手法 | ELECTRON MICROSCOPY (4.26 Å) | | 主引用文献 | PAM binding ensures orientational integration during Cas4-Cas1-Cas2-mediated CRISPR adaptation.
Mol.Cell, 82, 2022
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7MID
 | | Sub-complex of Cas4-Cas1-Cas2 bound PAM containing DNA | | 分子名称: | CRISPR-associated endoribonuclease Cas2, CRISPR-associated exonuclease Cas4/endonuclease Cas1 fusion, DNA (33-MER), ... | | 著者 | Hu, C.Y, Ke, A.K. | | 登録日 | 2021-04-16 | | 公開日 | 2021-11-17 | | 最終更新日 | 2024-12-25 | | 実験手法 | ELECTRON MICROSCOPY (3.56 Å) | | 主引用文献 | Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas.
Nature, 598, 2021
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7MI4
 | | Symmetrical PAM-PAM prespacer bound Cas4/Cas1/Cas2 complex | | 分子名称: | CRISPR-associated endoribonuclease Cas2, CRISPR-associated exonuclease Cas4/endonuclease Cas1 fusion, DNA (35-MER), ... | | 著者 | Hu, C.Y, Ke, A.K. | | 登録日 | 2021-04-16 | | 公開日 | 2021-11-17 | | 最終更新日 | 2025-06-04 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas.
Nature, 598, 2021
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7MI9
 | | Full integration complex of Cas1/Cas2 from Cas4-containing system | | 分子名称: | CRISPR-associated endoribonuclease Cas2, CRISPR-associated exonuclease Cas4/endonuclease Cas1 fusion, DNA (5'-D(P*CP*GP*GP*AP*AP*AP*AP*GP*AP*GP*CP*C)-3'), ... | | 著者 | Hu, C.Y, Ke, A.K. | | 登録日 | 2021-04-16 | | 公開日 | 2021-11-17 | | 最終更新日 | 2025-05-28 | | 実験手法 | ELECTRON MICROSCOPY (3.89 Å) | | 主引用文献 | Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas.
Nature, 598, 2021
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7MI5
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7MIB
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7KFU
 | | Cas6-RT-Cas1--Cas2 complex | | 分子名称: | Cas2, Cas6-RT-Cas1 | | 著者 | Hoel, C.M, Wang, J.Y, Doudna, J.A, Brohawn, S.G. | | 登録日 | 2020-10-14 | | 公開日 | 2021-03-31 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural coordination between active sites of a CRISPR reverse transcriptase-integrase complex.
Nat Commun, 12, 2021
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7KFT
 | | Partial Cas6-RT-Cas1--Cas2 complex | | 分子名称: | Cas2, Cas6-RT-Cas1 | | 著者 | Hoel, C.M, Wang, J.Y, Doudna, J.A, Brohawn, S.G. | | 登録日 | 2020-10-14 | | 公開日 | 2021-03-31 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural coordination between active sites of a CRISPR reverse transcriptase-integrase complex.
Nat Commun, 12, 2021
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