PDB: 179 件ウェブページステータス検索Chemie searchBIRD

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8F3N	Crystal structure of Penicillin Binding Protein 5 (PBP5) T485A variant with S466 insertion penicillin bound form from Enterococcus faecium 分子名称: OPEN FORM - PENICILLIN G, Penicillin binding protein 5, SULFATE ION 著者 D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W. 登録日 2022-11-10 公開日 2023-07-05 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics Nat Commun, 2023
8F3R	Crystal structure of Penicillin Binding Protein 5 (PBP5) T485M T499I variant apo form from Enterococcus faecium 分子名称: Penicillin binding protein 5, SULFATE ION 著者 D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W. 登録日 2022-11-10 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics Nat Commun, 2023
8F3P	Crystal structure of Penicillin Binding Protein 5 (PBP5) R464A variant penicillin bound form from Enterococcus faecium 分子名称: OPEN FORM - PENICILLIN G, Penicillin binding protein 5, SULFATE ION 著者 D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W. 登録日 2022-11-10 公開日 2023-07-05 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.09 Å) 主引用文献 The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics Nat Commun, 2023
8F3M	Crystal structure of Penicillin Binding Protein 5 (PBP5) T485A variant with S466 insertion apo form from Enterococcus faecium 分子名称: Penicillin binding protein 5, SULFATE ION 著者 D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W. 登録日 2022-11-10 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics Nat Commun, 2023
8F3J	Crystal structure of Penicillin Binding Protein 5 (PBP5) T485A variant apo form from Enterococcus faecium 分子名称: Penicillin binding protein 5, SULFATE ION 著者 D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W. 登録日 2022-11-10 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics Nat Commun, 2023
8F3G	Crystal structure of Penicillin Binding Protein 5 (PBP5) T485M variant in the penicillin bound form from Enterococcus faecium 分子名称: OPEN FORM - PENICILLIN G, Penicillin binding protein 5, SULFATE ION 著者 D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W. 登録日 2022-11-10 公開日 2023-07-05 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.59 Å) 主引用文献 The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics Nat Commun, 2023
8F3Q	Crystal structure of Penicillin Binding Protein 5 (PBP5) Y460A variant apo form from Enterococcus faecium 分子名称: Penicillin binding protein 5, SULFATE ION 著者 D'Andrea, E.D, Schoenle, M.V, Choy, M.S, Page, R, Peti, W. 登録日 2022-11-10 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics Nat Commun, 2023
8BH1	Core divisome complex FtsWIQBL from Pseudomonas aeruginosa 分子名称: Cell division protein FtsB, Cell division protein FtsL, Cell division protein FtsQ, ... 著者 Kaeshammer, L, van den Ent, F, Jeffery, M, Lowe, J. 登録日 2022-10-28 公開日 2023-04-19 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Cryo-EM structure of the bacterial divisome core complex and antibiotic target FtsWIQBL. Nat Microbiol, 8, 2023
7ZG8	Crystal structure of A. baumannii penicillin-binding protein 2 分子名称: Peptidoglycan D,D-transpeptidase MrdA, ZINC ION 著者 Micelli, C, Crow, A, Roper, D.I. 登録日 2022-04-02 公開日 2023-02-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 A conserved zinc-binding site in Acinetobacter baumannii PBP2 required for elongasome-directed bacterial cell shape. Proc.Natl.Acad.Sci.USA, 120, 2023
7RD0	Crystal structure of C. difficile penicillin-binding protein 3 in apo form 分子名称: GLYCEROL, Penicillin-binding protein, ZINC ION 著者 Sacco, M, Chen, Y. 登録日 2021-07-08 公開日 2022-03-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A unique class of Zn 2+ -binding serine-based PBPs underlies cephalosporin resistance and sporogenesis in Clostridioides difficile. Nat Commun, 13, 2022
7RCW	Crystal structure of C. difficile penicillin-binding protein 2 in complex with ampicillin 分子名称: (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Sacco, M, Chen, Y. 登録日 2021-07-08 公開日 2022-03-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A unique class of Zn 2+ -binding serine-based PBPs underlies cephalosporin resistance and sporogenesis in Clostridioides difficile. Nat Commun, 13, 2022
7RCX	Crystal structure of C. difficile penicillin-binding protein 2 in apo form 分子名称: GLYCEROL, Penicillin-binding protein, SULFATE ION, ... 著者 Sacco, M, Chen, Y. 登録日 2021-07-08 公開日 2022-03-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 A unique class of Zn 2+ -binding serine-based PBPs underlies cephalosporin resistance and sporogenesis in Clostridioides difficile. Nat Commun, 13, 2022
7RCZ	Crystal structure of C. difficile SpoVD in complex with ampicillin 分子名称: (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... 著者 Sacco, M, Chen, Y. 登録日 2021-07-08 公開日 2022-03-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 A unique class of Zn 2+ -binding serine-based PBPs underlies cephalosporin resistance and sporogenesis in Clostridioides difficile. Nat Commun, 13, 2022
7RCY	Crystal structure of C. difficile penicillin-binding protein 2 in complex with ceftobiprole 分子名称: (2R)-2-[(1R)-1-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(hydroxyimino)acetyl]amino}-2-oxoethyl]-5-({2-oxo-1-[(3R)-pyr rolidin-3-yl]-2,5-dihydro-1H-pyrrol-3-yl}methyl)-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Penicillin-binding protein, ZINC ION 著者 Sacco, M, Chen, Y. 登録日 2021-07-08 公開日 2022-03-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A unique class of Zn 2+ -binding serine-based PBPs underlies cephalosporin resistance and sporogenesis in Clostridioides difficile. Nat Commun, 13, 2022
7ONY	Crystal structure of PBP3 from P. aeruginosa 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Freischem, S, Grimm, I, Weiergraeber, O.H. 登録日 2021-05-26 公開日 2021-08-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Interaction Mode of the Novel Monobactam AIC499 Targeting Penicillin Binding Protein 3 of Gram-Negative Bacteria. Biomolecules, 11, 2021
7ONZ	Crystal structure of PBP3 from P. aeruginosa 分子名称: GLYCEROL, Peptidoglycan D,D-transpeptidase FtsI 著者 Freischem, S, Grimm, I, Weiergraeber, O.H. 登録日 2021-05-26 公開日 2021-08-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Interaction Mode of the Novel Monobactam AIC499 Targeting Penicillin Binding Protein 3 of Gram-Negative Bacteria. Biomolecules, 11, 2021
7ONW	Crystal structure of PBP3 from E. coli in complex with AIC499 分子名称: (2S)-2-[(Z)-[1-(2-azanyl-1,3-thiazol-4-yl)-2-[[(2S)-3-methyl-1-oxidanylidene-3-(sulfooxyamino)butan-2-yl]amino]-2-oxidanylidene-ethylidene]amino]oxy-3-[4-[N-[(3R)-piperidin-3-yl]carbamimidoyl]phenoxy]propanoic acid, (4S)-2-METHYL-2,4-PENTANEDIOL, PHOSPHATE ION, ... 著者 Freischem, S, Grimm, I, Weiergraeber, O.H. 登録日 2021-05-26 公開日 2021-08-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Interaction Mode of the Novel Monobactam AIC499 Targeting Penicillin Binding Protein 3 of Gram-Negative Bacteria. Biomolecules, 11, 2021
7ONX	Crystal structure of PBP3 from P. aeruginosa 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, Peptidoglycan D,D-transpeptidase FtsI 著者 Freischem, S, Grimm, I, Weiergraeber, O.H. 登録日 2021-05-26 公開日 2021-08-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 Interaction Mode of the Novel Monobactam AIC499 Targeting Penicillin Binding Protein 3 of Gram-Negative Bacteria. Biomolecules, 11, 2021
7ONO	Crystal structure of PBP3 transpeptidase domain from E. coli 分子名称: Peptidoglycan D,D-transpeptidase FtsI, trimethylamine oxide 著者 Freischem, S, Grimm, I, Weiergraeber, O.H. 登録日 2021-05-25 公開日 2021-08-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Interaction Mode of the Novel Monobactam AIC499 Targeting Penicillin Binding Protein 3 of Gram-Negative Bacteria. Biomolecules, 11, 2021
7ONK	Crystal structure of PBP3 from P. aeruginosa in complex with AIC499 分子名称: (2S)-2-[(Z)-[1-(2-azanyl-1,3-thiazol-4-yl)-2-[[(2S)-3-methyl-1-oxidanylidene-3-(sulfooxyamino)butan-2-yl]amino]-2-oxidanylidene-ethylidene]amino]oxy-3-[4-[N-[(3R)-piperidin-3-yl]carbamimidoyl]phenoxy]propanoic acid, CHLORIDE ION, GLYCEROL, ... 著者 Freischem, S, Grimm, I, Weiergraeber, O.H. 登録日 2021-05-25 公開日 2021-08-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Interaction Mode of the Novel Monobactam AIC499 Targeting Penicillin Binding Protein 3 of Gram-Negative Bacteria. Biomolecules, 11, 2021
7ONN	Crystal structure of PBP3 transpeptidase domain from E. coli in complex with AIC499 分子名称: (2S)-2-[(Z)-[1-(2-azanyl-1,3-thiazol-4-yl)-2-[[(2S)-3-methyl-1-oxidanylidene-3-(sulfooxyamino)butan-2-yl]amino]-2-oxidanylidene-ethylidene]amino]oxy-3-[4-[N-[(3R)-piperidin-3-yl]carbamimidoyl]phenoxy]propanoic acid, DODECAETHYLENE GLYCOL, Peptidoglycan D,D-transpeptidase FtsI 著者 Freischem, S, Grimm, I, Weiergraeber, O.H. 登録日 2021-05-25 公開日 2021-08-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Interaction Mode of the Novel Monobactam AIC499 Targeting Penicillin Binding Protein 3 of Gram-Negative Bacteria. Biomolecules, 11, 2021
7OK9	Crystal structure of Penicillin-Binding Protein 1 (PBP1) from Staphylococcus aureus in complex with pentaglycine 分子名称: CADMIUM ION, CHLORIDE ION, Penicillin-binding protein 1, ... 著者 Martinez Caballero, S, Hermoso, J.A. 登録日 2021-05-17 公開日 2021-11-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.36 Å) 主引用文献 Integrative structural biology of the penicillin-binding protein-1 from Staphylococcus aureus , an essential component of the divisome machinery. Comput Struct Biotechnol J, 19, 2021
7O4B	Crystal structure of Penicillin-Binding Protein 1 (PBP1) from Staphylococcus aureus in complex with penicillin G 分子名称: CITRIC ACID, OPEN FORM - PENICILLIN G, Penicillin-binding protein 1, ... 著者 Martinez Caballero, S, Hermoso, J.A. 登録日 2021-04-05 公開日 2021-11-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.593 Å) 主引用文献 Integrative structural biology of the penicillin-binding protein-1 from Staphylococcus aureus , an essential component of the divisome machinery. Comput Struct Biotechnol J, 19, 2021
7O4A	Crystal structure of Penicillin-Binding Protein 1 (PBP1) from Staphylococcus aureus in complex with piperacillin 分子名称: Hydrolyzed piperacillin, Penicillin-binding protein 1 著者 Martinez Caballero, S, Hermoso, J.A. 登録日 2021-04-05 公開日 2021-11-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.028 Å) 主引用文献 Integrative structural biology of the penicillin-binding protein-1 from Staphylococcus aureus , an essential component of the divisome machinery. Comput Struct Biotechnol J, 19, 2021
7O49	Crystal structure of Penicillin-Binding Protein 1 (PBP1) from Staphylococcus aureus 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CADMIUM ION, CHLORIDE ION, ... 著者 Martinez Caballero, S, Hermoso, J.A. 登録日 2021-04-05 公開日 2021-11-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.03 Å) 主引用文献 Integrative structural biology of the penicillin-binding protein-1 from Staphylococcus aureus , an essential component of the divisome machinery. Comput Struct Biotechnol J, 19, 2021

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