PDB: 738 件ウェブページステータス検索Chemie searchBIRD

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1I83	BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH N1,N14-BIS((S-METHYL)ISOTHIOUREIDO)TETRADECANE (H4B FREE) 分子名称: ACETATE ION, GLYCEROL, N1,N14-BIS((S-METHYL)ISOTHIOUREIDO)TETRADECANE, ... 著者 Raman, C.S, Li, H, Martasek, P, Babu, B.R, Griffith, O.W, Masters, B.S.S, Poulos, T.L. 登録日 2001-03-12 公開日 2001-08-08 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Implications for isoform-selective inhibitor design derived from the binding mode of bulky isothioureas to the heme domain of endothelial nitric-oxide synthase. J.Biol.Chem., 276, 2001
1JWJ	Murine Inducible Nitric Oxide Synthase Oxygenase Dimer (Delta 65) with W457F Mutation at Tetrahydrobiopterin Binding Site 分子名称: 1,2-ETHANEDIOL, 5,6,7,8-TETRAHYDROBIOPTERIN, GLYCEROL, ... 著者 Aoyagi, M, Arvai, A.S, Ghosh, S, Stuehr, D.J, Tainer, J.A, Getzoff, E.D. 登録日 2001-09-04 公開日 2001-10-31 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structures of tetrahydrobiopterin binding-site mutants of inducible nitric oxide synthase oxygenase dimer and implicated roles of Trp457. Biochemistry, 40, 2001
1JWK	Murine Inducible Nitric Oxide Synthase Oxygenase Dimer (Delta 65) with W457A Mutation at Tetrahydrobiopterin Binding Site 分子名称: 1,2-ETHANEDIOL, 7,8-DIHYDROBIOPTERIN, GLYCEROL, ... 著者 Aoyagi, M, Arvai, A.S, Ghosh, S, Stuehr, D.J, Tainer, J.A, Getzoff, E.D. 登録日 2001-09-04 公開日 2001-10-31 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structures of tetrahydrobiopterin binding-site mutants of inducible nitric oxide synthase oxygenase dimer and implicated roles of Trp457. Biochemistry, 40, 2001
1K2R	Structure of rat brain nNOS heme domain complexed with NG-nitro-L-arginine 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, N-OMEGA-NITRO-L-ARGININE, ... 著者 Li, H, Martasek, P, Masters, B.S.S, Poulos, T.L, Raman, C.S. 登録日 2001-09-28 公開日 2003-03-04 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structure of rat brain nNOS heme domain To be Published
1K2S	Structure of rat brain nNOS heme domain complexed with NG-allyl-L-arginine 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, 5-N-ALLYL-ARGININE, ACETATE ION, ... 著者 Li, H, Martasek, P, Masters, B.S.S, Poulos, T.L, Raman, C.S. 登録日 2001-09-28 公開日 2003-03-04 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structure of rat brain nNOS heme domain To be Published
1K2T	Structure of rat brain nNOS heme domain complexed with S-ethyl-N-phenyl-isothiourea 分子名称: 2-ETHYL-1-PHENYL-ISOTHIOUREA, 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ... 著者 Li, H, Martasek, P, Masters, B.S.S, Poulos, T.L, Raman, C.S. 登録日 2001-09-28 公開日 2003-03-04 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of rat brain nNOS heme domain To be Published
1K2U	Structure of rat brain nNOS heme domain complexed with S-ethyl-N-[4-(trifluoromethyl)phenyl] isothiourea 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Li, H, Martasek, P, Masters, B.S.S, Poulos, T.L, Raman, C.S. 登録日 2001-09-28 公開日 2003-03-04 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of rat brain nNOS heme domain To be Published
1LZX	Rat neuronal NOS heme domain with NG-hydroxy-L-arginine bound 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, N-OMEGA-HYDROXY-L-ARGININE, ... 著者 Li, H, Shimizu, H, Flinspach, M, Jamal, J, Yang, W, Xian, M, Cai, T, Wen, E.Z, Jia, Q, Wang, P.G, Poulos, T.L. 登録日 2002-06-11 公開日 2002-11-27 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The Novel Binding Mode of N-Alkyl-N'-Hydroxyguanidine to Neuronal Nitric Oxide Synthase Provides Mechanistic Insights into NO Biosynthesis Biochemistry, 41, 2002
1LZZ	Rat neuronal NOS heme domain with N-isopropyl-N'-hydroxyguanidine bound 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, N-ISOPROPYL-N'-HYDROXYGUANIDINE, ... 著者 Li, H, Shimizu, H, Flinspach, M, Jamal, J, Yang, W, Xian, M, Cai, T, Wen, E.Z, Jia, Q, Wang, P.G, Poulos, T.L. 登録日 2002-06-11 公開日 2002-11-27 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 The Novel Binding Mode of N-Alkyl-N'-Hydroxyguanidine to Neuronal Nitric Oxide Synthase Provides Mechanistic Insights into NO Biosynthesis Biochemistry, 41, 2002
1M00	Rat neuronal NOS heme domain with N-butyl-N'-hydroxyguanidine bound 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, N-BUTYL-N'-HYDROXYGUANIDINE, ... 著者 Li, H, Shimizu, H, Flinspach, M, Jamal, J, Yang, W, Xian, M, Cai, T, Wen, E.Z, Jia, Q, Wang, P.G, Poulos, T.L. 登録日 2002-06-11 公開日 2002-11-27 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 The Novel Binding Mode of N-Alkyl-N'-Hydroxyguanidine to Neuronal Nitric Oxide Synthase Provides Mechanistic Insights into NO Biosynthesis Biochemistry, 41, 2002
1M7V	STRUCTURE OF A NITRIC OXIDE SYNTHASE HEME PROTEIN FROM BACILLUS SUBTILIS WITH TETRAHYDROFOLATE AND ARGININE BOUND 分子名称: (6S)-5,6,7,8-TETRAHYDROFOLATE, ARGININE, Nitric Oxide Synthase, ... 著者 Pant, K, Bilwes, A.M, Adak, S, Stuehr, D.J, Crane, B.R. 登録日 2002-07-22 公開日 2002-10-30 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure of a nitric oxide synthase heme protein from Bacillus subtilis. Biochemistry, 41, 2002
1M7Z	Structure of Nitric Oxide Synthase Heme Protein from Bacillus Subtilis with N-Hydroxy-Arginine and Tetrahydrofolate Bound 分子名称: (6S)-5,6,7,8-TETRAHYDROFOLATE, N-OMEGA-HYDROXY-L-ARGININE, Nitric oxide synthase, ... 著者 Pant, K, Bilwes, A.M, Adak, S, Stuehr, D.J, Crane, B.R. 登録日 2002-07-23 公開日 2002-10-30 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Structure of a nitric oxide synthase heme protein from Bacillus subtilis. Biochemistry, 41, 2002
1M8D	inducible nitric oxide synthase with Chlorzoxazone bound 分子名称: 1,2-ETHANEDIOL, 5,6,7,8-TETRAHYDROBIOPTERIN, CHLORZOXAZONE, ... 著者 Rosenfeld, R.J, Garcin, E.D, Panda, K, Andersson, G, Aberg, A, Wallace, A.V, Stuehr, D.J, Tainer, J.A, Getzoff, E.D. 登録日 2002-07-24 公開日 2002-08-14 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Conformational Changes in Nitric Oxide Synthases Induced by Chlorzoxazone and Nitroindazoles: Crystallographic and Computational Analyses of Inhibitor Potency Biochemistry, 41, 2002
1M8E	inducible nitric oxide synthase with 7-nitroindazole bound 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, 7-NITROINDAZOLE, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Rosenfeld, R.J, Garcin, E.D, Panda, K, Andersson, G, Aberg, A, Wallace, A.V, Stuehr, D.J, Tainer, J.A, Getzoff, E.D. 登録日 2002-07-24 公開日 2002-08-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Conformational Changes in Nitric Oxide Synthases Induced by Chlorzoxazone and Nitroindazoles: Crystallographic and Computational Analyses of Inhibitor Potency Biochemistry, 41, 2002
1M8H	inducible nitric oxide synthase with 6-nitroindazole bound 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, 6-NITROINDAZOLE, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Rosenfeld, R.J, Garcin, E.D, Panda, K, Andersson, G, Aberg, A, Wallace, A.V, Stuehr, D.J, Tainer, J.A, Getzoff, E.D. 登録日 2002-07-24 公開日 2002-08-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Conformational Changes in Nitric Oxide Synthases Induced by Chlorzoxazone and Nitroindazoles: Crystallographic and Computational Analyses of Inhibitor Potency Biochemistry, 41, 2002
1M8I	inducible nitric oxide synthase with 5-nitroindazole bound 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, 5-NITROINDAZOLE, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Rosenfeld, R.J, Garcin, E.D, Panda, K, Andersson, G, Aberg, A, Wallace, A.V, Stuehr, D.J, Tainer, J.A, Getzoff, E.D. 登録日 2002-07-24 公開日 2002-08-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Conformational Changes in Nitric Oxide Synthases Induced by Chlorzoxazone and Nitroindazoles: Crystallographic and Computational Analyses of Inhibitor Potency Biochemistry, 41, 2002
1M9J	human endothelial nitric oxide synthase with chlorzoxazone bound 分子名称: CHLORZOXAZONE, PROTOPORPHYRIN IX CONTAINING FE, ZINC ION, ... 著者 Rosenfeld, R.J, Garcin, E.D, Panda, K, Andersson, G, Aberg, A, Wallace, A.V, Stuehr, D.J, Tainer, J.A, Getzoff, E.D. 登録日 2002-07-29 公開日 2002-08-14 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Conformational Changes in Nitric Oxide Synthases Induced by Chlorzoxazone and Nitroindazoles: Crystallographic and Computational Analyses of Inhibitor Potency Biochemistry, 41, 2002
1M9K	Human Endothelial Nitric Oxide Synthase with 7-Nitroindazole Bound 分子名称: 7-NITROINDAZOLE, PROTOPORPHYRIN IX CONTAINING FE, ZINC ION, ... 著者 Rosenfeld, R.J, Garcin, E.D, Panda, K, Andersson, G, Aberg, A, Wallace, A.V, Stuehr, D.J, Tainer, J.A, Getzoff, E.D. 登録日 2002-07-29 公開日 2002-08-14 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Conformational Changes in Nitric Oxide Synthases Induced by Chlorzoxazone and Nitroindazoles: Crystallographic and Computational Analyses of Inhibitor Potency Biochemistry, 41, 2002
1M9M	human endothelial nitric oxide synthase with 6-nitroindazole bound 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 6-NITROINDAZOLE, ISOPROPYL ALCOHOL, ... 著者 Rosenfeld, R.J, Garcin, E.D, Panda, K, Andersson, G, Aberg, A, Wallace, A.V, Stuehr, D.J, Tainer, J.A, Getzoff, E.D. 登録日 2002-07-29 公開日 2002-08-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Conformational Changes in Nitric Oxide Synthases Induced by Chlorzoxazone and Nitroindazoles: Crystallographic and Computational Analyses of Inhibitor Potency Biochemistry, 41, 2002
1M9Q	human endothelial nitric oxide synthase with 5-nitroindazole bound 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 5-NITROINDAZOLE, ISOPROPYL ALCOHOL, ... 著者 Rosenfeld, R.J, Garcin, E.D, Panda, K, Andersson, G, Aberg, A, Wallace, A.V, Stuehr, D.J, Tainer, J.A, Getzoff, E.D. 登録日 2002-07-29 公開日 2002-08-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Conformational Changes in Nitric Oxide Synthases Induced by Chlorzoxazone and Nitroindazoles: Crystallographic and Computational Analyses of Inhibitor Potency Biochemistry, 41, 2002
1M9R	human endothelial nitric oxide synthase with 3-Bromo-7-Nitroindazole bound 分子名称: 3-BROMO-7-NITROINDAZOLE, PROTOPORPHYRIN IX CONTAINING FE, ZINC ION, ... 著者 Rosenfeld, R.J, Garcin, E.D, Panda, K, Andersson, G, Aberg, A, Wallace, A.V, Stuehr, D.J, Tainer, J.A, Getzoff, E.D. 登録日 2002-07-29 公開日 2002-08-14 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Conformational Changes in Nitric Oxide Synthases Induced by Chlorzoxazone and Nitroindazoles: Crystallographic and Computational Analyses of Inhibitor Potency Biochemistry, 41, 2002
1M9T	Inducible Nitric Oxide Synthase with 3-Bromo-7-Nitroindazole bound 分子名称: 1,2-ETHANEDIOL, 3-BROMO-7-NITROINDAZOLE, 5,6,7,8-TETRAHYDROBIOPTERIN, ... 著者 Rosenfeld, R.J, Garcin, E.D, Panda, K, Andersson, G, Aberg, A, Wallace, A.V, Stuehr, D.J, Tainer, J.A, Getzoff, E.D. 登録日 2002-09-05 公開日 2002-09-11 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Conformational Changes in Nitric Oxide Synthases Induced by Chlorzoxazone and Nitroindazoles: Crystallographic and Computational Analyses of Inhibitor Potency Biochemistry, 41, 2002
1MJT	CRYSTAL STRUCTURE OF SANOS, A BACTERIAL NITRIC OXIDE SYNTHASE OXYGENASE PROTEIN, IN COMPLEX WITH NAD+ AND SEITU 分子名称: ETHYLISOTHIOUREA, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, NITRIC-OXIDE SYNTHASE HOMOLOG, ... 著者 Bird, L.E, Ren, J, Stammers, D.K. 登録日 2002-08-28 公開日 2003-01-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of SANOS, a Bacterial Nitric Oxide Synthase Oxygenase Protein from Staphylococcus aureus Structure, 10, 2002
1MMV	Rat neuronal NOS heme domain with NG-propyl-L-arginine bound 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, N-OMEGA-PROPYL-L-ARGININE, ... 著者 Bretscher, L.E, Li, H, Poulos, T.L, Griffith, O.W. 登録日 2002-09-04 公開日 2003-09-16 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural characterization and kinetics of nitric-oxide synthase inhibition by novel N5-(iminoalkyl)- and N5-(iminoalkenyl)-ornithines J.Biol.Chem., 278, 2003
1MMW	Rat neuronal NOS heme domain with vinyl-L-NIO bound 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, N5-(1-IMINO-3-BUTENYL)-L-ORNITHINE, ... 著者 Bretscher, L.E, Li, H, Poulos, T.L, Griffith, O.W. 登録日 2002-09-04 公開日 2003-09-16 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural characterization and kinetics of nitric-oxide synthase inhibition by novel N5-(iminoalkyl)- and N5-(iminoalkenyl)-ornithines J.Biol.Chem., 278, 2003

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