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5XUK
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Crystal structure of Helicobacter pylori holo-[acyl-carrier-protein] synthase (AcpS) in complex with coenzyme A
分子名称: COENZYME A, Holo-[acyl-carrier-protein] synthase
著者Liao, Y.P, Wang, D.L, Yin, D.P, Zhang, Q.Y, Wang, Y.M, Wang, D.Q, Zhu, H.X, Chen, S.
登録日2017-06-23
公開日2018-06-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of acyl carrier protein synthases (AcpS) from three Gram-negative bacteria
To Be Published
5XU7
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Crystal structure of Escherichia coli holo-[acyl-carrier-protein] synthase (AcpS)
分子名称: CHLORIDE ION, GLYCEROL, Holo-[acyl-carrier-protein] synthase
著者Liao, Y.P, Wang, D.L, Yin, D.P, Zhang, Q.Y, Wang, Y.M, Wang, D.Q, Zhu, H.X, Chen, S.
登録日2017-06-22
公開日2018-06-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Crystal structures of acyl carrier protein synthases (AcpS) from three Gram-negative bacteria
To Be Published
5XUH
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Crystal structure of Escherichia coli holo-[acyl-carrier-protein] synthase (AcpS) D9A mutant in complex with CoA
分子名称: CHLORIDE ION, COENZYME A, GLYCEROL, ...
著者Liao, Y.P, Wang, D.L, Yin, D.P, Zhang, Q.Y, Wang, Y.M, Wang, D.Q, Zhu, H.X, Chen, S.
登録日2017-06-23
公開日2018-06-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Crystal structures of acyl carrier protein synthases (AcpS) from three Gram-negative bacteria
To Be Published
5XUM
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BU of 5xum by Molmil
Crystal structure of Thermotoga maritima holo-[acyl-carrier-protein] synthase (AcpS)
分子名称: GLYCEROL, Holo-[acyl-carrier-protein] synthase
著者Liao, Y.P, Wang, D.L, Yin, D.P, Zhang, Q.Y, Wang, Y.M, Wang, D.Q, Zhu, H.X, Chen, S.
登録日2017-06-23
公開日2018-06-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of acyl carrier protein synthases (AcpS) from three Gram-negative bacteria
To Be Published
2BDD
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BU of 2bdd by Molmil
Crystal Structure of Holo-ACP-synthase from Plasmodium yoelii
分子名称: ACP-synthase
著者Dong, A, Melone, M, Zhao, Y, Lew, J, Koeieradzki, I, Alam, Z, Wasney, G, Vedadi, M, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Amani, M, Structural Genomics Consortium (SGC)
登録日2005-10-20
公開日2005-11-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
3GWM
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BU of 3gwm by Molmil
Crystal structure of the holo-[Acyl-Carrier-Protein] Synthase (ACPS) from Mycobacterium smegmatis
分子名称: Holo-[acyl-carrier-protein] synthase, SULFATE ION
著者Poulsen, C, Wilmanns, M, Song, Y.H.
登録日2009-04-01
公開日2010-04-07
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of the holo-[Acyl-Carrier-Protein] Synthase (ACPS) from Mycobacterium
To be Published
3H7Q
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BU of 3h7q by Molmil
Crystal structure of the holo-[Acyl-Carrier-Protein] Synthase (ACPS) from Mycobacterium tuberculosis
分子名称: BICINE, Holo-[acyl-carrier-protein] synthase
著者Poulsen, C, Wilmanns, M, Song, Y.H.
登録日2009-04-28
公開日2010-04-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structure of the holo-[Acyl-Carrier-Protein] Synthase (ACPS) from Mycobacterium
To be Published
3HQJ
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BU of 3hqj by Molmil
Structure-function analysis of Mycobacterium tuberculosis acyl carrier protein synthase (AcpS).
分子名称: COENZYME A, Holo-[acyl-carrier-protein] synthase, MAGNESIUM ION
著者Dym, O, Albeck, S, Peleg, Y, Schwarz, A, Shakked, Z, Burstein, Y, Zimhony, O, Israel Structural Proteomics Center (ISPC)
登録日2009-06-07
公開日2009-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure-function analysis of the acyl carrier protein synthase (AcpS) from Mycobacterium tuberculosis.
J.Mol.Biol., 393, 2009
3HYK
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BU of 3hyk by Molmil
2.31 Angstrom resolution crystal structure of a holo-(acyl-carrier-protein) synthase from Bacillus anthracis str. Ames in complex with CoA (3',5'-ADP)
分子名称: ADENOSINE-3'-5'-DIPHOSPHATE, CHLORIDE ION, Holo-[acyl-carrier-protein] synthase, ...
著者Halavaty, A.S, Minasov, G, Skarina, T, Onopriyenko, O, Papazisi, L, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2009-06-22
公開日2009-06-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structural characterization and comparison of three acyl-carrier-protein synthases from pathogenic bacteria.
Acta Crystallogr.,Sect.D, 68, 2012
1QR0
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BU of 1qr0 by Molmil
CRYSTAL STRUCTURE OF THE 4'-PHOSPHOPANTETHEINYL TRANSFERASE SFP-COENZYME A COMPLEX
分子名称: 4'-PHOSPHOPANTETHEINYL TRANSFERASE SFP, COENZYME A, MAGNESIUM ION
著者Reuter, K, Mofid, R.M, Marahiel, A.M, Ficner, R.
登録日1999-06-17
公開日1999-12-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the surfactin synthetase-activating enzyme sfp: a prototype of the 4'-phosphopantetheinyl transferase superfamily.
EMBO J., 18, 1999
8GKF
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BU of 8gkf by Molmil
Phosphopantetheinyl transferase PptT from Mycobacterium tuberculosis in complex with Raltitrexed.
分子名称: 4'-phosphopantetheinyl transferase PptT, TOMUDEX
著者Krieger, I.V, Singh, A, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2023-03-18
公開日2024-03-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Redirecting raltitrexed from cancer cell thymidylate synthase to Mycobacterium tuberculosis phosphopantetheinyl transferase.
Sci Adv, 10, 2024
7B4R
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BU of 7b4r by Molmil
Structure of the 4'-phosphopantetheinyl transferase PptAb from Mycobacterium abscessus in complex with Coenzyme A and N-(2,6-diethylphenyl)-N'-(N-ethylcarbamimidoyl)urea
分子名称: COENZYME A, MANGANESE (II) ION, N-(2,6-diethylphenyl)-N'-(N-ethylcarbamimidoyl)urea, ...
著者Maveyraud, L, Carivenc, C, Blanger, C, Mourey, L.
登録日2020-12-02
公開日2021-11-10
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Phosphopantetheinyl transferase binding and inhibition by amidino-urea and hydroxypyrimidinethione compounds.
Sci Rep, 11, 2021
7B4S
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BU of 7b4s by Molmil
Structure of the 4'-phosphopantetheinyl transferase PptAb from Mycobacterium abscessus in complex with Coenzyme A and compound 153786 from the NCI Open Database
分子名称: 5-[(4-chlorophenyl)methyl]-6-[[2-(dimethylamino)ethylamino]methyl]-4-oxidanyl-1~{H}-pyrimidine-2-thione, COENZYME A, MANGANESE (II) ION, ...
著者Maveyraud, L, Carivenc, C, Mourey, L.
登録日2020-12-02
公開日2021-11-10
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献Phosphopantetheinyl transferase binding and inhibition by amidino-urea and hydroxypyrimidinethione compounds.
Sci Rep, 11, 2021
7N8L
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PptT PAP(CoA) 9016 complex
分子名称: 4'-phosphopantetheinyl transferase PptT, COENZYME A, DIMETHYL SULFOXIDE, ...
著者Mosior, J.W, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2021-06-15
公開日2022-02-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献In Vitro and In Vivo Inhibition of the Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT by Amidinoureas.
J.Med.Chem., 65, 2022
7N8E
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PptT PAP(CoA) 9056 complex
分子名称: 4'-phosphopantetheinyl transferase PptT, COENZYME A, DIMETHYL SULFOXIDE, ...
著者Mosior, J.W, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2021-06-14
公開日2022-02-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献In Vitro and In Vivo Inhibition of the Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT by Amidinoureas.
J.Med.Chem., 65, 2022
7N8M
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BU of 7n8m by Molmil
PptT PAP(CoA) 8978B complex
分子名称: 4'-phosphopantetheinyl transferase PptT, COENZYME A, DIMETHYL SULFOXIDE, ...
著者Mosior, J.W, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2021-06-15
公開日2022-02-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献In Vitro and In Vivo Inhibition of the Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT by Amidinoureas.
J.Med.Chem., 65, 2022
4QJK
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BU of 4qjk by Molmil
Crystal structure of M. tuberculosis phosphopantetheinyl transferase PptT
分子名称: COENZYME A, Phosphopantetheinyl transferase PptT, SULFATE ION
著者Noel, J.P, Burkart, M.D, Vickery, C.R.
登録日2014-06-04
公開日2014-07-16
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Structure, biochemistry, and inhibition of essential 4'-phosphopantetheinyl transferases from two species of mycobacteria.
Acs Chem.Biol., 9, 2014
4QJL
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BU of 4qjl by Molmil
Crystal structure of M. ulcerans phosphopantetheinyl transferase MuPPT
分子名称: COENZYME A, MAGNESIUM ION, Phosphopantetheinyl transferase, ...
著者Noel, J.P, Burkart, M.D, Vickery, C.R.
登録日2014-06-04
公開日2014-07-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure, biochemistry, and inhibition of essential 4'-phosphopantetheinyl transferases from two species of mycobacteria.
Acs Chem.Biol., 9, 2014
2BYD
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BU of 2byd by Molmil
Structure of aminoadipate-semialdehyde dehydrogenase- phosphopantetheinyl transferase
分子名称: BROMIDE ION, HSPC223
著者Bunkoczi, G, Wu, X, Dubinina, E, Johansson, C, Smee, C, Turnbull, A, Oppermann, U, von Delft, F, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J.
登録日2005-07-29
公開日2005-08-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mechanism and substrate recognition of human holo ACP synthase.
Chem. Biol., 14, 2007
4U89
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BU of 4u89 by Molmil
4'-phosphopantetheinyl transferase PptT from Mycobacterium tuberculosis
分子名称: COENZYME A, IMIDAZOLE, PHOSPHATE ION, ...
著者Faille, A, Mourey, L, Pedelacq, J.D.
登録日2014-08-01
公開日2015-08-26
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献X-ray structure of the 4'-phosphopantetheinyl transferase PptT from Mycobacterium tuberculosis
to be published
2C43
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STRUCTURE OF AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE- PHOSPHOPANTETHEINYL TRANSFERASE IN COMPLEX WITH COENZYME A
分子名称: AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINYL TRANSFERASE, CHLORIDE ION, COENZYME A, ...
著者Bunkoczi, G, Wu, X, Dubinina, E, Johansson, C, Smee, C, Turnbull, A, von Delft, F, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, Oppermann, U.
登録日2005-10-14
公開日2005-10-24
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Mechanism and substrate recognition of human holo ACP synthase.
Chem. Biol., 14, 2007
7ED2
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BU of 7ed2 by Molmil
Transferase from Mycobacterium smegmatis
分子名称: 4'-phosphopantetheinyl transferase, ADENOSINE-3'-5'-DIPHOSPHATE, MAGNESIUM ION
著者Kim, D.-G, Lee, B.-J, Lee, S.J.
登録日2021-03-15
公開日2022-03-16
最終更新日2024-08-14
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Transferase from Mycobacterium tuberculosis
To Be Published
7ED1
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Transferase from Mycobacterium smegmatis
分子名称: 4'-phosphopantetheinyl transferase, COENZYME A, MAGNESIUM ION, ...
著者Kim, D.-G, Lee, B.-J, Lee, S.J.
登録日2021-03-15
公開日2022-03-16
最終更新日2024-08-14
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Transferase from Mycobacterium smegmatis
To Be Published
7ED0
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Transferase from Mycobacterium tuberculosis
分子名称: 4'-phosphopantetheinyl transferase superfamily protein, COENZYME A, SULFATE ION
著者Kim, D.-G, Lee, B.-J, Lee, S.J.
登録日2021-03-15
公開日2022-03-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Transferase from Mycobacterium tuberculosis
To Be Published
7BCZ
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Structure of the 4'-phosphopantetheinyl transferase PcpS from Pseudomonas aeruginosa
分子名称: 4'-phosphopantetheinyl transferase EntD, COENZYME A, MAGNESIUM ION, ...
著者Carivenc, C, Mourey, L, Pedelacq, J.D.
登録日2020-12-21
公開日2021-11-10
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Phosphopantetheinyl transferase binding and inhibition by amidino-urea and hydroxypyrimidinethione compounds.
Sci Rep, 11, 2021

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件を2024-09-11に公開中

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