PDB: 140 件ウェブページステータス検索Chemie searchBIRD

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1LRO	Aquifex aeolicus KDO8P synthase H185G mutant in complex with PEP and Cadmium 分子名称: CADMIUM ION, KDO-8-phosphate synthetase, PHOSPHATE ION, ... 著者 Wang, J, Duewel, H.S, Stuckey, J.A, Woodard, R.W, Gatti, D.L. 登録日 2002-05-15 公開日 2002-11-27 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Function of His185 in Aquifex aeolicus 3-Deoxy-D-manno-octulosonate 8-Phosphate Synthase J.Mol.Biol., 324, 2002
2A21	Aquifex aeolicus KDO8PS in complex with PEP, PO4, and Zn2+ 分子名称: 2-dehydro-3-deoxyphosphooctonate aldolase, PHOSPHATE ION, PHOSPHOENOLPYRUVATE, ... 著者 Kona, F, Xu, X, Lu, J, Martin, P, Gatti, D.L. 登録日 2005-06-21 公開日 2006-06-20 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Electronic structure of the metal center in the Cd(2+), Zn(2+), and Cu(2+) substituted forms of KDO8P synthase: implications for catalysis. Biochemistry, 48, 2009
1T8X	r106g kdo8ps with pep and a5p 分子名称: 2-dehydro-3-deoxyphosphooctonate aldolase, ARABINOSE-5-PHOSPHATE, CADMIUM ION, ... 著者 Gatti, D.L. 登録日 2004-05-13 公開日 2005-06-14 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Effects of the Arg106==>Gly mutation on the catalytic and conformational cycle of Aquifex aeolicus KDO8P synthase. To be Published
1LRQ	Aquifex aeolicus KDO8P synthase H185G mutant in complex with PEP, A5P and Cadmium 分子名称: ARABINOSE-5-PHOSPHATE, CADMIUM ION, KDO-8-phosphate synthetase, ... 著者 Wang, J, Duewel, H.S, Stuckey, J.A, Woodard, R.W, Gatti, D.L. 登録日 2002-05-15 公開日 2002-11-27 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Function of His185 in Aquifex aeolicus 3-Deoxy-D-manno-octulosonate 8-Phosphate Synthase J.Mol.Biol., 324, 2002
4C1L	Crystal structure of pyrococcus furiosus 3-deoxy-D-arabino- heptulosonate 7-phosphate synthase I181D interface mutant 分子名称: 2-dehydro-3-deoxyphosphoheptonate aldolase, CHLORIDE ION, MANGANESE (II) ION, ... 著者 Nazmi, A.R, Schofield, L.R, Dobson, R.C.J, Jameson, G.B, Parker, E.J. 登録日 2013-08-13 公開日 2013-11-20 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Destabilization of the homotetrameric assembly of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from the hyperthermophile Pyrococcus furiosus enhances enzymatic activity. J. Mol. Biol., 426, 2014
5D03	Neisseria meningitidis 3 deoxy-D-arabino-heptulosonate 7-phosphate synthase Val223Ala variant 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Heyes, L.C, Parker, E.J. 登録日 2015-08-02 公開日 2016-08-10 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Neisseria meningitidis 3 deoxy-D-arabino-heptulosonate 7-phosphate synthase Val223Ala variant at 1.84 Angstroms resolution To Be Published
1PCW	Aquifex aeolicus KDO8PS in complex with cadmium and APP, a bisubstrate inhibitor 分子名称: 1-DEOXY-6-O-PHOSPHONO-1-[(PHOSPHONOMETHYL)AMINO]-L-THREO-HEXITOL, 2-dehydro-3-deoxyphosphooctonate aldolase, CADMIUM ION 著者 Xu, X, Wang, J, Grison, C, Petek, S, Coutrot, P, Birck, M, Woodard, R.W, Gatti, D.L. 登録日 2003-05-17 公開日 2004-02-17 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure-Based Design of Novel Inhibitors of 3-Deoxy-D-manno-octulosonate 8-Phosphate Synthase. Drug DES.DISCOVERY, 18, 2003
1FWW	AQUIFEX AEOLICUS KDO8P SYNTHASE IN COMPLEX WITH PEP, A5P AND CADMIUM 分子名称: 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATE ALDOLASE, ARABINOSE-5-PHOSPHATE, CADMIUM ION, ... 著者 Duewel, H.S, Radaev, S, Wang, J, Woodard, R.W, Gatti, D.L. 登録日 2000-09-24 公開日 2001-04-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Electronic structure of the metal center in the Cd(2+), Zn(2+), and Cu(2+) substituted forms of KDO8P synthase: implications for catalysis. Biochemistry, 48, 2009
1T96	r106g kdo8ps with pep 分子名称: 2-dehydro-3-deoxyphosphooctonate aldolase, CADMIUM ION, PHOSPHATE ION, ... 著者 Gatti, D.L. 登録日 2004-05-14 公開日 2005-06-14 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Effects of the Arg106==>Gly mutation on the catalytic and conformational cycle of Aquifex aeolicus KDO8P synthase. To be Published
4JTG	Crystal structure of F114R/R117A mutant of 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis 分子名称: 2-dehydro-3-deoxyphosphooctonate aldolase, CHLORIDE ION, GLYCEROL, ... 著者 Allison, T.M, Cochrane, F.C, Jameson, G.B, Parker, E.J. 登録日 2013-03-23 公開日 2013-06-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Examining the Role of Intersubunit Contacts in Catalysis by 3-Deoxy-d-manno-octulosonate 8-Phosphate Synthase. Biochemistry, 52, 2013
3FS2	Crystal structure of 2-Dehydro-3-Deoxyphosphooctonate aldolase from Bruciella melitensis at 1.85A resolution 分子名称: 2-dehydro-3-deoxyphosphooctonate aldolase, PHOSPHATE ION, TETRAETHYLENE GLYCOL 著者 SSGCID, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2009-01-09 公開日 2009-01-20 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal structure of 2-Dehydro-3-Deoxyphosphooctonate aldolase from Bruciella melitensis at 1.85A resolution To be Published
3FYP	Crystal structure of the quadruple mutant (N23C/C246S/D247E/P249A) of 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis 分子名称: 3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase, CHLORIDE ION, GLYCEROL, ... 著者 Jameson, G.B, Parker, E.J, Cochrane, F.P, Patchett, M.L. 登録日 2009-01-22 公開日 2009-03-31 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Reversing evolution: re-establishing obligate metal ion dependence in a metal-independent KDO8P synthase J.Mol.Biol., 390, 2009
1T99	r106g kdo8ps without substrates 分子名称: 2-dehydro-3-deoxyphosphooctonate aldolase, CADMIUM ION, PHOSPHATE ION 著者 Gatti, D.L. 登録日 2004-05-16 公開日 2005-06-14 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Effects of the Arg106==>Gly mutation on the catalytic and conformational cycle of Aquifex aeolicus KDO8P synthase. To be Published
4JTK	Crystal structure of R117Q mutant of 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis 分子名称: 2-dehydro-3-deoxyphosphooctonate aldolase, CHLORIDE ION, SODIUM ION 著者 Allison, T.M, Cochrane, F.C, Jameson, G.B, Parker, E.J. 登録日 2013-03-23 公開日 2013-06-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Examining the Role of Intersubunit Contacts in Catalysis by 3-Deoxy-d-manno-octulosonate 8-Phosphate Synthase. Biochemistry, 52, 2013
1OFO	Crystal Structure of the Tyrosine Regulated 3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate Synthase from Saccharomyces Cerevisiae in Complex with 2-Phosphoglycolate 分子名称: 2-PHOSPHOGLYCOLIC ACID, PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE 著者 Koenig, V, Pfeil, A, Heinrich, G, Braus, G, Schneider, T.R. 登録日 2003-04-17 公開日 2004-04-15 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Substrate and Metal Complexes of 3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate Synthase from Saccharomyces Cerevisiae Provide New Insights Into the Catalytic Mechanism. J.Mol.Biol., 337, 2004
5D02	Neisseria meningitidis 3 deoxy-D-arabino-heptulosonate 7-phosphate synthase Glu176Gln variant 分子名称: 1,2-ETHANEDIOL, MANGANESE (II) ION, PHOSPHOENOLPYRUVATE, ... 著者 Heyes, L.C. 登録日 2015-08-02 公開日 2016-08-10 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Neisseria meningitidis 3 deoxy-D-arabino-heptulosonate 7-phosphate synthase Glu176Gln variant at 1.87 Angstroms resolution To Be Published
1FY6	AQUIFEX AEOLICUS KDO8P SYNTHASE IN COMPLEX WITH CADMIUM AND A5P 分子名称: 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATE ALDOLASE, ARABINOSE-5-PHOSPHATE, CADMIUM ION, ... 著者 Duewel, H.S, Radaev, S, Wang, J, Woodard, R.W, Gatti, D.L. 登録日 2000-09-28 公開日 2001-04-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Substrate and metal complexes of 3-deoxy-D-manno-octulosonate-8-phosphate synthase from Aquifex aeolicus at 1.9-A resolution. Implications for the condensation mechanism. J.Biol.Chem., 276, 2001
4JTE	Crystal structure of F114A mutant of 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis 分子名称: 2-dehydro-3-deoxyphosphooctonate aldolase, CHLORIDE ION, SODIUM ION 著者 Allison, T.M, Cochrane, F.C, Jameson, G.B, Parker, E.J. 登録日 2013-03-23 公開日 2013-06-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Examining the Role of Intersubunit Contacts in Catalysis by 3-Deoxy-d-manno-octulosonate 8-Phosphate Synthase. Biochemistry, 52, 2013
1FWS	AQUIFEX AEOLICUS KDO8P SYNTHASE IN COMPLEX WITH PEP AND CADMIUM 分子名称: 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATE ALDOLASE, CADMIUM ION, PHOSPHATE ION, ... 著者 Duewel, H.S, Radaev, S, Wang, J, Woodard, R.W, Gatti, D.L. 登録日 2000-09-24 公開日 2001-04-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Electronic structure of the metal center in the Cd(2+), Zn(2+), and Cu(2+) substituted forms of KDO8P synthase: implications for catalysis. Biochemistry, 48, 2009
1FWT	AQUIFEX AEOLICUS KDO8P SYNTHASE IN COMPLEX WITH PEP, E4P AND CADMIUM 分子名称: 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATE ALDOLASE, CADMIUM ION, ERYTHOSE-4-PHOSPHATE, ... 著者 Duewel, H.S, Radaev, S, Wang, J, Woodard, R.W, Gatti, D.L. 登録日 2000-09-24 公開日 2001-04-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Substrate and metal complexes of 3-deoxy-D-manno-octulosonate-8-phosphate synthase from Aquifex aeolicus at 1.9-A resolution. Implications for the condensation mechanism. J.Biol.Chem., 276, 2001
1HFB	Crystal structure of the tyrosine-regulated 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Saccharomyces cerevisiae complexed with phosphoenolpyruvate 分子名称: PHOSPHOENOLPYRUVATE, TYROSINE-REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE 著者 Schneider, T.R, Hartmann, M, Braus, G.H. 登録日 2000-11-30 公開日 2003-01-14 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Evolution of Feedback-Inhibited Beta /Alpha Barrel Isoenzymes by Gene Duplication and a Single Mutation Proc.Natl.Acad.Sci.USA, 100, 2003
1OAB	CRYSTAL STRUCTURE OF THE TYROSINE REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE FROM SACCHAROMYCES CEREVISIAE IN COMPLEX WITH PHOSPHOENOLPYRUVATE AND MANGANESE(II) 分子名称: MANGANESE (II) ION, PHOSPHOENOLPYRUVATE, TYROSINE-REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE 著者 Koenig, V, Pfeil, A, Heinrich, G, Braus, G.H, Schneider, T.R. 登録日 2003-01-06 公開日 2004-01-23 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Substrate and Metal Complexes of 3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate Synthase from Saccharomyces Cerevisiae Provide New Insights Into the Catalytic Mechanism J.Mol.Biol., 337, 2004
3STF	Crystal structure of a mutant (S211A) of 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis 分子名称: 2-dehydro-3-deoxyphosphooctonate aldolase, CHLORIDE ION, GLYCEROL, ... 著者 Allison, T.M, Jameson, G.B, Gloyne, B.J, Parker, E.J. 登録日 2011-07-09 公開日 2011-11-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 An Extended (beta)7(alpha)7 Substrate-Binding Loop Is Essential for Efficient Catalysis by 3-Deoxy-D-manno-Octulosonate 8-Phosphate Synthase Biochemistry, 50, 2011
1JCY	Aquifex aeolicus KDO8P synthase in complex with R5P, PEP and Cadmium 分子名称: 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATE ALDOLASE, CADMIUM ION, PHOSPHATE ION, ... 著者 Wang, J, Duewel, H.S, Woodard, R.W, Gatti, D.L. 登録日 2001-06-11 公開日 2002-01-16 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structures of Aquifex aeolicus KDO8P synthase in complex with R5P and PEP, and with a bisubstrate inhibitor: role of active site water in catalysis. Biochemistry, 40, 2001
3FYO	Crystal structure of the triple mutant (N23C/D247E/P249A) of 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis 分子名称: 3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase, CHLORIDE ION, MANGANESE (II) ION, ... 著者 Jameson, G.B, Parker, E.J, Cochrane, F.P, Patchett, M.L. 登録日 2009-01-22 公開日 2009-03-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Reversing evolution: re-establishing obligate metal ion dependence in a metal-independent KDO8P synthase J.Mol.Biol., 390, 2009

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