4C1L
Crystal structure of pyrococcus furiosus 3-deoxy-D-arabino- heptulosonate 7-phosphate synthase I181D interface mutant
Summary for 4C1L
| Entry DOI | 10.2210/pdb4c1l/pdb |
| Related | 4C1K |
| Descriptor | 2-dehydro-3-deoxyphosphoheptonate aldolase, MANGANESE (II) ION, CHLORIDE ION, ... (6 entities in total) |
| Functional Keywords | transferase, shikimate pathway, interface mutant |
| Biological source | Pyrococcus furiosus |
| Total number of polymer chains | 2 |
| Total formula weight | 59093.45 |
| Authors | Nazmi, A.R.,Schofield, L.R.,Dobson, R.C.J.,Jameson, G.B.,Parker, E.J. (deposition date: 2013-08-13, release date: 2013-11-20, Last modification date: 2023-12-20) |
| Primary citation | Nazmi, A.R.,Schofield, L.R.,Dobson, R.C.,Jameson, G.B.,Parker, E.J. Destabilization of the homotetrameric assembly of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from the hyperthermophile Pyrococcus furiosus enhances enzymatic activity. J. Mol. Biol., 426:656-673, 2014 Cited by PubMed: 24239948DOI: 10.1016/j.jmb.2013.11.008 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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