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4C1L

Crystal structure of pyrococcus furiosus 3-deoxy-D-arabino- heptulosonate 7-phosphate synthase I181D interface mutant

Functional Information from GO Data
ChainGOidnamespacecontents
A0003849molecular_function3-deoxy-7-phosphoheptulonate synthase activity
A0009058biological_processbiosynthetic process
A0009073biological_processaromatic amino acid family biosynthetic process
A0016740molecular_functiontransferase activity
A0016832molecular_functionaldehyde-lyase activity
A0046872molecular_functionmetal ion binding
B0003849molecular_function3-deoxy-7-phosphoheptulonate synthase activity
B0009058biological_processbiosynthetic process
B0009073biological_processaromatic amino acid family biosynthetic process
B0016740molecular_functiontransferase activity
B0016832molecular_functionaldehyde-lyase activity
B0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE MN A 1263
ChainResidue
ACYS31
AHIS201
AGLU227
AASP238

site_idAC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE CL A 1264
ChainResidue
ALYS136
AARG166
AHIS201
AHOH2120
AHOH2127

site_idAC3
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MN B 1263
ChainResidue
BCYS31
BHIS201
BGLU227
BASP238
BCL1267

site_idAC4
Number of Residues4
DetailsBINDING SITE FOR RESIDUE 1PE B 1264
ChainResidue
BMET1
BLYS2
BSER4
BGLU6

site_idAC5
Number of Residues5
DetailsBINDING SITE FOR RESIDUE CL B 1265
ChainResidue
BLYS136
BARG166
BHIS201
BHOH2122
BHOH2125

site_idAC6
Number of Residues5
DetailsBINDING SITE FOR RESIDUE CL B 1266
ChainResidue
BARG55
BGLN111
BLYS136
BHIS201
BCL1267

site_idAC7
Number of Residues6
DetailsBINDING SITE FOR RESIDUE CL B 1267
ChainResidue
BARG55
BLYS60
BHIS201
BMN1263
BCL1266
BHOH2061

site_idAC8
Number of Residues6
DetailsBINDING SITE FOR RESIDUE K B 1268
ChainResidue
BTHR170
BGLU172
BHOH2152
BHOH2154
BHOH2157
BHOH2159

site_idAC9
Number of Residues6
DetailsBINDING SITE FOR RESIDUE K A 1265
ChainResidue
ATHR170
AGLU172
AHOH2170
AHOH2171
AHOH2172
AHOH2174

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PDB entries from 2024-11-06

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