7ZD9
 
 | | Crystal structure of the E352T mutant of S-adenosyl-L-homocysteine hydrolase from Synechocystis sp. PCC 6803 cocrystallized with adenosine in the presence of Rb+ cations | | 分子名称: | ADENOSINE, Adenosylhomocysteinase, CHLORIDE ION, ... | | 著者 | Malecki, P.H, Imiolczyk, B, Wozniak, K, Brzezinski, K. | | 登録日 | 2022-03-29 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Biochemical and structural insights into an unusual, alkali-metal-independent S-adenosyl-L-homocysteine hydrolase from Synechocystis sp. PCC 6803.
Acta Crystallogr D Struct Biol, 78, 2022
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1K0U
 | | Inhibition of S-adenosylhomocysteine Hydrolase by "acyclic sugar" Adenosine Analogue D-eritadenine | | 分子名称: | D-ERITADENINE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE | | 著者 | Takusagawa, F, Huang, Y, Komoto, J, Takata, Y, Gomi, T, Ogawa, H, Fujioka, M, Powell, D. | | 登録日 | 2001-09-20 | | 公開日 | 2001-10-17 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Inhibition of S-adenosylhomocysteine hydrolase by acyclic sugar adenosine analogue D-eritadenine. Crystal structure of S-adenosylhomocysteine hydrolase complexed with D-eritadenine.
J.Biol.Chem., 277, 2002
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5AXD
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5AXC
 | | Crystal structure of mouse SAHH complexed with 3'-keto aristeromycin | | 分子名称: | (2S,3R,5R)-3-(6-amino-9H-purin-9-yl)-2-hydroxy-5-(hydroxymethyl)cyclopentanone, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Kusakabe, Y, Ishihara, M, Tanaka, N. | | 登録日 | 2015-07-24 | | 公開日 | 2016-07-27 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Crystal structure of mouse SAHH complexed with 3'-keto aristeromycin
To Be Published
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5M5K
 | | S-adenosyl-L-homocysteine hydrolase from Bradyrhizobium elkanii in complex with adenosine and cordycepin | | 分子名称: | 3'-DEOXYADENOSINE, ACETATE ION, ADENOSINE, ... | | 著者 | Manszewski, T, Mueller-Dieckamann, J, Jaskolski, M. | | 登録日 | 2016-10-21 | | 公開日 | 2017-05-10 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Crystallographic and SAXS studies of S-adenosyl-l-homocysteine hydrolase from Bradyrhizobium elkanii.
IUCrJ, 4, 2017
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5M65
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1KY4
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5M66
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1KY5
 | | D244E mutant S-Adenosylhomocysteine hydrolase refined with noncrystallographic restraints | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 3'-OXO-ADENOSINE, S-adenosylhomocysteine hydrolase | | 著者 | Takata, Y, Takusagawa, F. | | 登録日 | 2002-02-03 | | 公開日 | 2002-09-25 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Catalytic Mechanism of S-adenosylhomocysteine hydrolase. Site-directed
mutagenesis of Asp-130, Lys-185, Asp-189, and Asn-190.
J.Biol.Chem., 277, 2002
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5M67
 | | Crystal structure of S-adenosyl-L-homocysteine hydrolase from Bradyrhizobium elkanii in complex with adenine and 2'-deoxyadenosine | | 分子名称: | (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol, ACETATE ION, ADENINE, ... | | 著者 | Manszewski, T, Jaskolski, M. | | 登録日 | 2016-10-24 | | 公開日 | 2017-05-10 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Crystallographic and SAXS studies of S-adenosyl-l-homocysteine hydrolase from Bradyrhizobium elkanii.
IUCrJ, 4, 2017
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1LI4
 | | Human S-adenosylhomocysteine hydrolase complexed with neplanocin | | 分子名称: | 3-(6-AMINO-PURIN-9-YL)-5-HYDROXYMETHYL-CYCLOPENTANE-1,2-DIOL, ISOPROPYL ALCOHOL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Yang, X, Hu, Y, Yin, D.H, Turner, M.A, Wang, M, Borchardt, R.T, Howell, P.L, Kuczera, K, Schowen, R.L. | | 登録日 | 2002-04-17 | | 公開日 | 2003-05-20 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Catalytic strategy of S-adenosyl-L-homocysteine hydrolase: Transition-state
stabilization and the avoidance of abortive reactions
Biochemistry, 42, 2003
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7R39
 | | Crystal structure of S-adenosyl-L-homocysteine hydrolase from Sulfolobus acidocaldarius in complex with adenosine | | 分子名称: | ADENOSINE, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Saleem-Batcha, R, Popadic, D, Andexer, J.N. | | 登録日 | 2022-02-06 | | 公開日 | 2023-02-15 | | 最終更新日 | 2024-09-18 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure, function and substrate preferences of archaeal S-adenosyl-L-homocysteine hydrolases.
Commun Biol, 7, 2024
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7R3A
 | | Crystal structure of S-adenosyl-L-homocysteine hydrolase from Methanococcus maripaludis in complex with inosine | | 分子名称: | INOSINE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, S-inosyl-L-homocysteine hydrolase, ... | | 著者 | Saleem-Batcha, R, Popadic, D, Andexer, J.N. | | 登録日 | 2022-02-06 | | 公開日 | 2023-02-15 | | 最終更新日 | 2024-09-18 | | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | | 主引用文献 | Structure, function and substrate preferences of archaeal S-adenosyl-L-homocysteine hydrolases.
Commun Biol, 7, 2024
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7R37
 | | Crystal structure of S-adenosyl-L-homocysteine hydrolase from Pyrococcus furiosus in complex with inosine | | 分子名称: | Adenosylhomocysteinase, INOSINE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Saleem-Batcha, R, Popadic, D, Andexer, J.N. | | 登録日 | 2022-02-06 | | 公開日 | 2023-02-15 | | 最終更新日 | 2024-09-18 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Structure, function and substrate preferences of archaeal S-adenosyl-L-homocysteine hydrolases.
Commun Biol, 7, 2024
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7R38
 | | Crystal structure of S-adenosyl-L-homocysteine hydrolase from Pyrococcus furiosus in complex with S-inosyl-L-homocysteine | | 分子名称: | (2S)-2-AMINO-4-({[(2S,3S,4R,5R)-3,4-DIHYDROXY-5-(6-OXO-1,6-DIHYDRO-9H-PURIN-9-YL)TETRAHYDROFURAN-2-YL]METHYL}THIO)BUTANOIC ACID, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Saleem-Batcha, R, Popadic, D, Andexer, J.N. | | 登録日 | 2022-02-06 | | 公開日 | 2023-02-15 | | 最終更新日 | 2024-09-18 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structure, function and substrate preferences of archaeal S-adenosyl-L-homocysteine hydrolases.
Commun Biol, 7, 2024
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3GLQ
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3GVP
 | | Human SAHH-like domain of human adenosylhomocysteinase 3 | | 分子名称: | Adenosylhomocysteinase 3, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Siponen, M.I, Wisniewska, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Karlberg, T, Kotenyova, T, Lehtio, L, Moche, M, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Schutz, P, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Schueler, H. | | 登録日 | 2009-03-31 | | 公開日 | 2009-06-09 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Human S-adenosyl homocysteine hydrolase-like 2 protein crystal structure
To be Published
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5AXA
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5AXB
 | | Crystal structure of mouse SAHH complexed with noraristeromycin | | 分子名称: | (1S,2R,3S,4R)-4-(6-aminopurin-9-yl)cyclopentane-1,2,3-triol, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Kusakabe, Y, Ishihara, M, Tanaka, N. | | 登録日 | 2015-07-24 | | 公開日 | 2016-07-27 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Crystal structure of mouse SAHH complexed with noraristeromycin
To Be Published
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3G1U
 | | Crystal structure of Leishmania major S-adenosylhomocysteine hydrolase | | 分子名称: | ADENOSINE, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Siponen, M.I, Welin, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Karlberg, T, Kotenyova, T, Lehtio, L, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Schutz, P, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Wisniewska, M, Schueler, H, Structural Genomics Consortium (SGC) | | 登録日 | 2009-01-30 | | 公開日 | 2009-02-10 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of Leishmania major S-adenosylhomocysteine hydrolase
To be Published
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3H9U
 | | S-adenosyl homocysteine hydrolase (SAHH) from Trypanosoma brucei | | 分子名称: | ADENOSINE, Adenosylhomocysteinase, GLYCEROL, ... | | 著者 | Siponen, M.I, Schutz, P, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Karlberg, T, Kragh Nielsen, T, Kotenyova, T, Kotzsch, A, Moche, M, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Schueler, H, Structural Genomics Consortium (SGC) | | 登録日 | 2009-04-30 | | 公開日 | 2009-09-29 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of S-adenosyl homocysteine hydrolase (SAHH) from Trypanosoma brucei
To be Published
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7ZD4
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7ZD0
 | | Crystal structure of Pseudomonas aeruginosa S-adenosyl-L-homocysteine hydrolase inhibited by Cd2+ ions | | 分子名称: | 1,3-PROPANDIOL, 1,4-BUTANEDIOL, ADENOSINE, ... | | 著者 | Malecki, P.H, Gawel, M, Brzezinski, K. | | 登録日 | 2022-03-29 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Crystal structure of Pseudomonas aeruginosa S-adenosyl-L-homocysteine hydrolase inhibited by Cd2+ ions
To Be Published
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7ZD1
 | | Crystal structure of Pseudomonas aeruginosa S-adenosyl-L-homocysteine hydrolase inhibited by Hg2+ ions | | 分子名称: | 1,3-PROPANDIOL, 1,4-BUTANEDIOL, ADENOSINE, ... | | 著者 | Malecki, P.H, Gawel, M, Brzezinski, K. | | 登録日 | 2022-03-29 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | Crystal structure of Pseudomonas aeruginosa S-adenosyl-L-homocysteine hydrolase inhibited by Hg2+ ions
To Be Published
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7ZD3
 | | Crystal structure of Pseudomonas aeruginosa S-adenosyl-L-homocysteine hydrolase inhibited by Zn2+ ions | | 分子名称: | 1,3-PROPANDIOL, 1,4-BUTANEDIOL, ADENOSINE, ... | | 著者 | Malecki, P.H, Gawel, M, Brzezinski, K. | | 登録日 | 2022-03-29 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of Pseudomonas aeruginosa S-adenosyl-L-homocysteine hydrolase inhibited by Zn2+ ions
To Be Published
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