PDB: 41 件ウェブページステータス検索Chemie searchBIRD

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6N9G	Crystal Structure of RGS7-Gbeta5 dimer 分子名称: Guanine nucleotide-binding protein subunit beta-5, Regulator of G-protein signaling 7 著者 Patil, D.N, Rangarajan, E, Izard, T, Martemyanov, K.A. 登録日 2018-12-03 公開日 2019-01-09 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.129 Å) 主引用文献 Structural organization of a major neuronal G protein regulator, the RGS7-G beta 5-R7BP complex. Elife, 7, 2018
2PBI	The multifunctional nature of Gbeta5/RGS9 revealed from its crystal structure 分子名称: GLYCEROL, Guanine nucleotide-binding protein subunit beta 5, Regulator of G-protein signaling 9 著者 Cheever, M.L, Snyder, J.T, Gershburg, S, Siderovski, D.P, Harden, T.K, Sondek, J. 登録日 2007-03-28 公開日 2008-01-29 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of the multifunctional Gbeta5-RGS9 complex. Nat.Struct.Mol.Biol., 15, 2008
6H7E	GEF regulatory domain 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SULFATE ION, cDNA FLJ56134, ... 著者 Ferrandez, Y, Cherfils, J, Peurois, F. 登録日 2018-07-31 公開日 2020-02-19 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Membranes prime the RapGEF EPAC1 to transduce cAMP signaling. Nat Commun, 14, 2023
2BYV	Structure of the cAMP responsive exchange factor Epac2 in its auto- inhibited state 分子名称: RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 4 著者 Rehmann, H, Wittinghofer, A, Bos, J.L. 登録日 2005-08-08 公開日 2006-02-02 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure of the Cyclic-AMP Responsive Exchange Factor Epac2 in its Auto-Inhibited State Nature, 439, 2006
8ADL	Cryo-EM structure of the SEA complex 分子名称: Maintenance of telomere capping protein 5, Nitrogen permease regulator 2, Nitrogen permease regulator 3, ... 著者 Tafur, L, Loewith, R. 登録日 2022-07-08 公開日 2022-11-02 最終更新日 2023-05-10 実験手法 ELECTRON MICROSCOPY (2.95 Å) 主引用文献 Cryo-EM structure of the SEA complex. Nature, 611, 2022
8AE6	Cryo-EM structure of the SEA complex wing (SEACIT) 分子名称: Maintenance of telomere capping protein 5, Nitrogen permease regulator 2, Nitrogen permease regulator 3, ... 著者 Tafur, L, Loewith, R. 登録日 2022-07-12 公開日 2022-11-02 最終更新日 2023-05-10 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Cryo-EM structure of the SEA complex. Nature, 611, 2022
7SHF	Cryo-EM structure of GPR158 coupled to the RGS7-Gbeta5 complex 分子名称: (2S)-1-{[(S)-hydroxy{[(1s,2R,3R,4R,5S,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl (5E,8E,11E,14E)-icosa-5,8,11,14-tetraenoate, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, CHOLESTEROL, ... 著者 Patil, D.N, Singh, S, Singh, A.K, Martemyanov, K.A. 登録日 2021-10-08 公開日 2021-12-01 最終更新日 2022-01-19 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Cryo-EM structure of human GPR158 receptor coupled to the RGS7-G beta 5 signaling complex. Science, 375, 2022
7EWP	Cryo-EM structure of human GPR158 in complex with RGS7-Gbeta5 in a 2:1:1 ratio 分子名称: Guanine nucleotide-binding protein subunit beta-5, Probable G-protein coupled receptor 158, Regulator of G-protein signaling 7 著者 Kim, Y, Jeong, E, Jeong, J, Cho, Y. 登録日 2021-05-25 公開日 2021-12-01 最終更新日 2022-02-16 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Structure of the class C orphan GPCR GPR158 in complex with RGS7-G beta 5. Nat Commun, 12, 2021
7EWR	Cryo-EM structure of human GPR158 in complex with RGS7-Gbeta5 in a 2:2:2 ratio 分子名称: Guanine nucleotide-binding protein subunit beta-5, Probable G-protein coupled receptor 158, Regulator of G-protein signaling 7 著者 Kim, Y, Jeong, E, Jeong, J, Cho, Y. 登録日 2021-05-26 公開日 2021-12-01 最終更新日 2022-02-16 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Structure of the class C orphan GPCR GPR158 in complex with RGS7-G beta 5. Nat Commun, 12, 2021
7OWG	human DEPTOR in a complex with mutant human mTORC1 A1459P 分子名称: DEP domain-containing mTOR-interacting protein, Regulatory-associated protein of mTOR, Serine/threonine-protein kinase mTOR, ... 著者 Heimhalt, M, Berndt, A, Wagstaff, J, Anandapadamanaban, M, Perisic, O, Maslen, S, McLaughlin, S, Yu, W.-H, Masson, G.R, Boland, A, Ni, X, Yamashita, K, Murshudov, G.N, Skehel, M, Freund, S.M, Williams, R.L. 登録日 2021-06-18 公開日 2021-09-08 最終更新日 2022-02-23 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Bipartite binding and partial inhibition links DEPTOR and mTOR in a mutually antagonistic embrace. Elife, 10, 2021
7PEC	cryo-EM structure of DEPTOR bound to human mTOR complex 1, DEPt-bound subset local refinement 分子名称: DEP domain-containing mTOR-interacting protein, INOSITOL HEXAKISPHOSPHATE, Regulatory-associated protein of mTOR, ... 著者 Waelchli, M, Maier, T. 登録日 2021-08-09 公開日 2021-09-08 最終更新日 2021-09-29 実験手法 ELECTRON MICROSCOPY (4.24 Å) 主引用文献 Regulation of human mTOR complexes by DEPTOR. Elife, 10, 2021
7PEB	cryo-EM structure of DEPTOR bound to human mTOR complex 1, focussed on one protomer 分子名称: DEP domain-containing mTOR-interacting protein, INOSITOL HEXAKISPHOSPHATE, Regulatory-associated protein of mTOR, ... 著者 Waelchli, M, Maier, T. 登録日 2021-08-09 公開日 2021-09-08 最終更新日 2021-09-29 実験手法 ELECTRON MICROSCOPY (3.67 Å) 主引用文献 Regulation of human mTOR complexes by DEPTOR. Elife, 10, 2021
7PE8	cryo-EM structure of DEPTOR bound to human mTOR complex 2, focussed on one protomer 分子名称: ACETYL GROUP, DEP domain-containing mTOR-interacting protein, INOSITOL HEXAKISPHOSPHATE, ... 著者 Waelchli, M, Maier, T. 登録日 2021-08-09 公開日 2021-09-08 最終更新日 2021-09-29 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Regulation of human mTOR complexes by DEPTOR. Elife, 10, 2021
7PE9	cryo-EM structure of DEPTOR bound to human mTOR complex 2, DEPt-bound subset local refinement 分子名称: ACETYL GROUP, DEP domain-containing mTOR-interacting protein, INOSITOL HEXAKISPHOSPHATE, ... 著者 Waelchli, M, Maier, T. 登録日 2021-08-09 公開日 2021-09-08 最終更新日 2021-09-29 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Regulation of human mTOR complexes by DEPTOR. Elife, 10, 2021
7PEA	cryo-EM structure of DEPTOR bound to human mTOR complex 1, overall refinement 分子名称: DEP domain-containing mTOR-interacting protein, INOSITOL HEXAKISPHOSPHATE, Regulatory-associated protein of mTOR, ... 著者 Waelchli, M, Maier, T. 登録日 2021-08-09 公開日 2021-09-08 最終更新日 2021-09-29 実験手法 ELECTRON MICROSCOPY (4.07 Å) 主引用文献 Regulation of human mTOR complexes by DEPTOR. Elife, 10, 2021
7PE7	cryo-EM structure of DEPTOR bound to human mTOR complex 2, overall refinement 分子名称: ACETYL GROUP, DEP domain-containing mTOR-interacting protein, INOSITOL HEXAKISPHOSPHATE, ... 著者 Waelchli, M, Maier, T. 登録日 2021-08-09 公開日 2021-09-15 最終更新日 2021-09-29 実験手法 ELECTRON MICROSCOPY (3.41 Å) 主引用文献 Regulation of human mTOR complexes by DEPTOR. Elife, 10, 2021

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